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Concentrated, botanically based serums for every skin concern. Discover Active Serum for blemish-prone skin, Hydra-Cool Serum for hydration and comfort, Super Serum Advance+, Pro-Heal Serum Advance+ and GeneXC for vitamin C and brightness, Youth Serum for smoothing, and the Retinol+ Emulsions for texture and fine lines.

iS Clinical Active Serum | Serum - Clarifying | LOSHEN & CREMiS Clinical Active Serum | Serum - Clarifying | LOSHEN & CREM
iS Clinical Active Serum Regular price From $127.00 CAD 15 ml
iS Clinical Pro-Heal Serum Advance+ | Serum - Vitamin C | LOSHEN & CREMiS Clinical Pro-Heal Serum Advance+ | Serum - Vitamin C | LOSHEN & CREM
iS Clinical Pro-Heal Serum Advance+ Regular price From $137.00 CAD 15 ml
iS Clinical Hydra-Cool Serum | Serum - Hydrating | LOSHEN & CREMiS Clinical Hydra-Cool Serum | Serum - Hydrating | LOSHEN & CREM
iS Clinical Hydra-Cool Serum Regular price From $92.00 CAD 15 ml
iS Clinical Super Serum Advance+ | Serum - Vitamin C | LOSHEN & CREMiS Clinical Super Serum Advance+ | Serum - Vitamin C | LOSHEN & CREM
iS Clinical Super Serum Advance+ Regular price From $137.00 CAD 15 ml
iS Clinical Retinol+ Emulsion 0.3 | Cream - Retinol 0.3% | LOSHEN & CREM
iS Clinical Retinol+ Emulsion 0.3 Regular price $149.00 CAD 1 oz
Sold out iS Clinical Brightening Serum | Serum - Hyperpigmentation | LOSHEN & CREMiS Clinical Brightening Serum | Serum - Hyperpigmentation | LOSHEN & CREM
iS Clinical Poly-Vitamin Serum | Serum - Hydrating | LOSHEN & CREMiS Clinical Poly-Vitamin Serum | Serum - Hydrating | LOSHEN & CREM
iS Clinical Poly-Vitamin Serum Regular price From $104.00 CAD 15 ml
iS Clinical GeneXC Serum | Serum - Healthy Aging | LOSHEN & CREMiS Clinical GeneXC Serum | Serum - Healthy Aging | LOSHEN & CREM
iS Clinical GeneXC Serum Regular price From $151.00 CAD 15 ml
iS Clinical Retinol+ Emulsion 1.0 | Cream - Retinol 1% | LOSHEN & CREM
iS Clinical Retinol+ Emulsion 1.0 Regular price $179.00 CAD 30 g
iS Clinical Youth Serum | Serum - Lifting | Firming | LOSHEN & CREMiS Clinical Youth Serum | Serum - Lifting | Firming | LOSHEN & CREM
iS Clinical Youth Serum Regular price $229.00 CAD 30 ml

A closer look at iS Clinical Serums.

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Compare these products
What matters to you iS Clinical Active SerumiS Clinical Pro-Heal Serum Advance+iS Clinical Hydra-Cool Serum
At a glance Blemishes, Uneven texture, Dark spots & uneven tone, Oily skin & pores, Visible poresSensitive skin, Redness, BlemishesDehydrated skin, Sensitive skin, Redness
Product type Serum - ClarifyingSerum - Vitamin CSerum - Hydrating
Price From $127.00 CAD 15 ml From $137.00 CAD 15 ml From $92.00 CAD 15 ml

iS Clinical Active Serum

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iS Clinical Pro-Heal Serum Advance+

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iS Clinical Hydra-Cool Serum

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The Loshen & Crem experience.

Thoughtful skincare. People who care.

An illustrated Loshen & Crem parcel with branded tape and a gold oval seal.

From our boutique to your door

Your Loshen parcel.

A carefully prepared parcel, finished with our Loshen & Crem tape and signature gold oval seal.

Complimentary skincare samples are included with every order.

A question before or after your order? Our client-care team is here to help.

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Delivery & complimentary samples

In Canada, regular shipping is complimentary from $149 CAD and priority shipping from $249 CAD, after discounts and before tax. Complimentary skincare samples are included with every order. Product and destination restrictions apply. See our shipping policy for U.S. orders, transit estimates and applicable charges.

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La Crem Rewards

Join La Crem Rewards for free and earn points on eligible purchases according to your membership tier. Exchange points for an available reward in your account. Your points do not expire. Eligibility, minimum purchases and exclusions depend on the reward you choose.

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Returns, explained

For eligible regular-price items, request a return within 30 days of delivery. Products must be unopened, unused and in their original, undamaged packaging. Please wait for authorization before sending anything back. Return shipping is the client’s responsibility. Final-sale exclusions and the full policy apply.

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The people behind Loshen & Crem

Founded by facialist Sarah-Maude Cabana, Loshen & Crem is a skincare boutique and facial studio in Edmonton. Kassandra leads our client experience, and Abby leads our esthetics team. Start with client care for help with products, routines and orders.

Meet Loshen & Crem
Kassandra
Kassandra
Abby
Abby

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