
Introducing
P.E.A.R.L.
A first-of-its-kind regenerative fusion combining advanced cell signaling and PDRN to redefine skin renewal. D
eveloped by pioneers in science-forward skin rejuvenation, AnteAGE introduces P.E.A.R.L.™, an innovative protocol designed to support recovery, strengthen skin function, and enhance overall skin quality.
This advanced regenerative approach helps improve firmness, elasticity, luminosity, and barrier resilience, making it ideal for supporting post-procedure skin or revitalizing compromised, tired, or aging skin. Suitable for all skin types.
Highest Standards from
Lab to Label
At AnteAGE®’s California headquarters, development follows academic best practices and internationally recognized scientific guidelines. Their processes evolve alongside ongoing breakthroughs in skin science, setting a high standard for regenerative ingredient sourcing, formulation integrity, and manufacturing excellence.

BIOSOMES
Bioengineered for proven precision. Our Biosomes behave just as Exosomes do, but in a biosynthetic, lipid-based formula, ideal for those seeking a non-human-derived solution.
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P.E.A.R.L
Transmitters of transformation. This advanced regenerative signaling system delivers biologically active messengers that support cellular communication, helping guide the skin’s natural repair and renewal processes from within.
Book hereYour Questions Answered
Yes.
At Loshen & Crem, P.E.A.R.L.™ is used exclusively as a post-microneedling booster to support optimal recovery and maximize treatment effectiveness.
This system is suitable for anyone looking to:
- Enhance the overall results of ablative aesthetic treatments
- Improve firmness, texture, and radiance
- Reduce the look of scars, pigmentation, or uneven tone
- Support hydration, elasticity, and youthful skin behavior
- Accelerate recovery and soothe irritated or sensitized skin
Microneedling creates micro-channels in the skin, allowing P.E.A.R.L.™ to penetrate deeply.
Its growth factors, regenerative actives, and PDRN work together to:
- Strengthen the repair response
- Boost collagen and elastin renewal
- Brighten and even the complexion
- Reduce visible inflammation more quickly
The result is smoother, more radiant, more resilient skin.
Yes. The formula is engineered to be compatible with all skin types, including sensitive or mature skin.
It is the only product on the market that combines both Regenerative actives and PDRN into one cohesive system. This dual-technology approach works synergistically to significantly boost skin repair and collagen production.
Most clients experience:
- Reduced redness and faster post-procedure comfort
- Brighter, more even-looking skin
- Improved firmness and elasticity
- A smoother texture with refined appearance of pores and scars
Results continue to progress over several weeks as regeneration unfolds.










