Your routine
iS ClinicalCleansing Complex
Why it fits
The cleansing step, before serums.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsNew to retinol
A gentle encapsulated retinol with bakuchiol that refines texture, softens fine lines and evens the look of tone. A good first retinol.
Discover the formula & ingredientsPickup in Edmonton
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Let’s talk about your skin and what belongs in your routine.
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Selected with care.
iS Clinical
Your ritual begins with the right choice.
$149.00 CAD
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The skincare focus
A gentle encapsulated retinol with bakuchiol that refines texture, softens fine lines and evens the look of tone. A good first retinol.
Explore our ingredient glossaryiS Clinical
The ingredients behind this formula—and what they bring to your skin.
Retinol
Refines and smooths.
Bakuchiol
Supports smoothing.
Ectoin and Squalane
Comfort.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Explore another step in your face-care routine.
Your routine
The cleansing step, before serums.
Your routine
A hydrating serum before moisturizer.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
iS Clinical Retinol+ Emulsion 0.3 is an easy introduction to retinol.
Encapsulated retinol and bakuchiol smooth and refine, while squalane, hyaluronic acid and ectoin keep skin comfortable.
Skin looks smoother, more even and refined.
New to retinol
Go slowly; no peels on retinol nights.
Water/Aqua/Eau, Glycerin, Squalane, Pentylene Glycol, Sodium Hyaluronate, Ectoin, Glyceryl Citrate/Lactate/Linoleate/Oleate, Polyglyceryl-4 Cocoate, Polyglyceryl-3 Cocoate, Glyceryl Caprylate, Chlorella Vulgaris Extract, Tocopherol, Butylene Glycol, Bakuchiol, Triethanolamine, Carbomer, Retinol, Phragmites Communis Extract, Poria Cocos Extract, Oryza Sativa (Rice) Bran Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Phosphatidylcholine, Propanediol, Butyrospermum Parkii (Shea) Butter, Polysorbate 20, Caprylic/Capric Triglyceride, Lecithin, Lactic Acid, Polysorbate 40, Helianthus Annuus (Sunflower) Extract, Phenoxyethanol, Polyacrylamide, C13-14 Isoalkane, Laureth-7, Tripeptide-1, Dextran, Ascorbic Acid, Colloidal Gold, Glutathione, Panthenol, Heptyl Undecylenate, C13-16 Isoalkane, Dipotassium Glycyrrhizate, Bidens Pilosa Extract, Elaeis Guineensis (Palm) Oil, Gossypium Herbaceum (Cotton) Seed Oil, Linum Usitatissimum (Linseed) Seed Oil, Glycine Soja (Soybean) Extract, Sodium Hydroxide, Disodium EDTA, Phenylpropanol, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Diisopropyl Adipate, Triethyl Citrate, Xanthan Gum, Sorbitol, Fragrance/Parfum.
Ingredients may be updated by the manufacturer. Please refer to the product packaging for the most current ingredient list.
For delivery and return information, view our policy.
iS Clinical Retinol+ Emulsion 0.3 is a lightweight evening emulsion with encapsulated retinol, bakuchiol and Extremozymes®. It helps refine rough texture, soften the look of fine lines and wrinkles, and even the look of tone, while squalane, hyaluronic acid and ectoin keep skin comfortable. A good first retinol from iS Clinical.
Go slowly: some dryness or flaking as skin adjusts is normal. Don’t use it on the same night as peels or other exfoliants. Do not use retinol if you are pregnant or breastfeeding; ask your healthcare provider.
Water/Aqua/Eau, Glycerin, Squalane, Pentylene Glycol, Sodium Hyaluronate, Ectoin, Glyceryl Citrate/Lactate/Linoleate/Oleate, Polyglyceryl-4 Cocoate, Polyglyceryl-3 Cocoate, Glyceryl Caprylate, Chlorella Vulgaris Extract, Tocopherol, Butylene Glycol, Bakuchiol, Triethanolamine, Carbomer, Retinol, Phragmites Communis Extract, Poria Cocos Extract, Oryza Sativa (Rice) Bran Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Phosphatidylcholine, Propanediol, Butyrospermum Parkii (Shea) Butter, Polysorbate 20, Caprylic/Capric Triglyceride, Lecithin, Lactic Acid, Polysorbate 40, Helianthus Annuus (Sunflower) Extract, Phenoxyethanol, Polyacrylamide, C13-14 Isoalkane, Laureth-7, Tripeptide-1, Dextran, Ascorbic Acid, Colloidal Gold, Glutathione, Panthenol, Heptyl Undecylenate, C13-16 Isoalkane, Dipotassium Glycyrrhizate, Bidens Pilosa Extract, Elaeis Guineensis (Palm) Oil, Gossypium Herbaceum (Cotton) Seed Oil, Linum Usitatissimum (Linseed) Seed Oil, Glycine Soja (Soybean) Extract, Sodium Hydroxide, Disodium EDTA, Phenylpropanol, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Diisopropyl Adipate, Triethyl Citrate, Xanthan Gum, Sorbitol, Fragrance/Parfum.
Ingredients may be updated by the manufacturer. Please refer to the product packaging for the most current ingredient list.
0.3 or 1.0?
Start with 0.3. Move to 1.0 only once your skin is comfortable with regular retinol use.
Where can I buy iS Clinical Retinol+ Emulsion 0.3 in Canada?
iS Clinical Retinol+ Emulsion 0.3 is available from Loshen & Crem online across Canada and at our Edmonton, Alberta boutique.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Refines and smooths.
Supports smoothing.
Comfort.
Hydrates.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover iS Clinical Retinol+ Emulsion 0.3 at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the iS Clinical collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.