Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsPersistent dark spots and uneven-looking tone
A short-contact, rinse-off cream with 7% cysteamine and Isobionic-Amide™ for persistent dark spots and uneven-looking tone.
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For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
Selected with care.
Cyspera
Your ritual begins with the right choice.
$255.00 CAD
Taxes calculated at checkout.
The skincare focus
A short-contact, rinse-off cream with 7% cysteamine and Isobionic-Amide™ for persistent dark spots and uneven-looking tone.
Explore our ingredient glossaryCyspera
The ingredients behind this formula—and what they bring to your skin.
Cysteamine 7%
the targeted ingredient in this short-contact formula for uneven-looking pigmentation.
Isobionic-Amide™
part of Cyspera’s proprietary complex, used alongside cysteamine.
Glycerin
helps maintain a hydrated skin feel.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Explore another step in your face-care routine.
Your routine
The cream step for dehydrated, stressed skin, applied after Lotion P50 and your Sérums Quintessentiels. It brings lasting hydration and an immediate boost of radiance to finish the routine.
Your routine
The cleansing step and the first step of your Biologique Recherche routine, removing makeup, sunscreen and impurities before your Lotion P50.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Cyspera Intensive is the targeted dark-spot step in the routine. Its cysteamine complex helps reduce the look of dark spots and uneven tone over time, for a more even-looking complexion.
Apply it to dry, unwashed skin, leave on briefly, then cleanse it away. Follow with Ageless or your recommended moisturizer. Consistency and daily sun protection are central to the routine.
Why a short application? Intensive is designed to work during a limited contact time. Start with 5 minutes and build to 15 minutes as tolerated; leaving it on longer is not the goal. Use daily for 16 weeks, then twice weekly for maintenance. Progress varies: compare photos in the same lighting every four weeks.
Persistent dark spots and uneven-looking tone
Aqua/Water, Cysteamine HCl, Isobionic-Amide, Paraffinum Liquidum/Mineral Oil, Glycolic Acid, Potassium Cetyl Phosphate, Glycerin, Isopropyl Myristate, Cetyl Alcohol, Sodium Ascorbyl Phosphate, Arachidyl Alcohol, Butyrospermum Parkii (Shea Butter), Ascorbyl Palmitate, Xanthan Gum, Behenyl Alcohol, Propylheptyl Caprylate, Octyldodecanol, Ethylhexylglycerin, Parfum/Fragrance, Arachidyl Glucoside, Tocopherol, Helianthus Annuus (Sunflower) Seed Oil, Disodium EDTA, Acetyl Cedrene, Amyl Salicylate, Tetramethyl Acetyloctahydronaphthalenes.
Follow the 16-week daily phase and compare photos every four weeks in consistent lighting. The published cases are individual examples, not a promised timeline.
No. It is a rinse-off step. Begin at 5 minutes and do not exceed 15 minutes; follow your packaging and your skin’s tolerance.
Intensive is the short-contact dark-spot step; Neutralize cleanses it away; Ageless is the leave-on care that follows. Finish your morning routine with sunscreen.
Choose one short-contact formula for the same area. Ask our team which one fits your skin and existing routine.
For delivery and return information, view our policy.
Cyspera Intensive is the targeted dark-spot step in the routine. Its cysteamine complex helps reduce the look of dark spots and uneven tone over time, for a more even-looking complexion.
Format: One 30 ml bottle of Cyspera Intensive.
Apply it to dry, unwashed skin, leave on briefly, then cleanse it away. Follow with Ageless or your recommended moisturizer. Consistency and daily sun protection are central to the routine.
Why a short application? Intensive is designed to work during a limited contact time. Start with 5 minutes and build to 15 minutes as tolerated; leaving it on longer is not the goal. Use daily for 16 weeks, then twice weekly for maintenance. Progress varies: compare photos in the same lighting every four weeks.
1. Apply a thin layer to dry, unwashed skin. If you have cleansed, wait at least one hour.
2. Start with 5 minutes; gradually increase to a maximum of 15 minutes as tolerated.
3. Cleanse thoroughly and pat dry. If using Neutralize, massage two pumps directly over Intensive, then rinse.
4. Apply Ageless or your recommended moisturizer and leave on.
5. Use Intensive once daily for 16 weeks, then twice weekly for maintenance. Apply broad-spectrum SPF 30 or higher every morning.
Aqua/Water, Cysteamine HCl, Isobionic-Amide, Paraffinum Liquidum/Mineral Oil, Glycolic Acid, Potassium Cetyl Phosphate, Glycerin, Isopropyl Myristate, Cetyl Alcohol, Sodium Ascorbyl Phosphate, Arachidyl Alcohol, Butyrospermum Parkii (Shea Butter), Ascorbyl Palmitate, Xanthan Gum, Behenyl Alcohol, Propylheptyl Caprylate, Octyldodecanol, Ethylhexylglycerin, Parfum/Fragrance, Arachidyl Glucoside, Tocopherol, Helianthus Annuus (Sunflower) Seed Oil, Disodium EDTA, Acetyl Cedrene, Amyl Salicylate, Tetramethyl Acetyloctahydronaphthalenes.
The ingredient list on your packaging is the reference.
When should I assess my progress?
Follow the 16-week daily phase and compare photos every four weeks in consistent lighting. The published cases are individual examples, not a promised timeline.
Do I leave Intensive on overnight?
No. It is a rinse-off step. Begin at 5 minutes and do not exceed 15 minutes; follow your packaging and your skin’s tolerance.
Which product does what?
Intensive is the short-contact dark-spot step; Neutralize cleanses it away; Ageless is the leave-on care that follows. Finish your morning routine with sunscreen.
Can I use Intensive and Sensitive together?
Choose one short-contact formula for the same area. Ask our team which one fits your skin and existing routine.
Follow the directions on your packaging. Avoid eyes, mucous membranes and broken or irritated skin. Stop and seek advice if irritation persists. Ask our team before combining with exfoliating acids or retinoids. Daily sunscreen is essential.
Published Cyspera case photographs, with the original Day 0, Day 28 and Day 84 labels. View the change in uneven-looking tone across each series.
Individual results vary. These images are shown as published by Cyspera distributor Medevo. The exact formulation and full regimen are not identified for these panels; they do not show results for the current Intensive formula used on its own.
View the published Cyspera cases and source information.
The care behind your order
A few helpful details, before your next delivery.
Track your orderDelivery
For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
the targeted ingredient in this short-contact formula for uneven-looking pigmentation.
part of Cyspera’s proprietary complex, used alongside cysteamine.
helps maintain a hydrated skin feel.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Cyspera Intensive at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Cyspera collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
Curious about…
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