Your routine
iS ClinicalCleansing Complex
Why it fits
The cleansing step, before serums.
iS Clinical Retinol+ Emulsion 1.0
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Explore La Crem rewardsExperienced retinol users
A maximum-strength encapsulated retinol with bakuchiol for experienced retinol users, best used with professional guidance.
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Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Selected with care.
iS Clinical
Retinol+ Emulsion 1.0
Your ritual begins with the right choice.
$214.00 CAD
Taxes calculated at checkout.
The skincare focus
For experienced retinol users.
A maximum-strength encapsulated retinol with bakuchiol for experienced retinol users, best used with professional guidance.
Explore our ingredient glossaryiS Clinical
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Retinol
Refines and smooths.
Bakuchiol
Supports smoothing.
Butyrospermum Parkii (Shea) Butter and Squalane
Comfort.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Explore another step in your face-care routine.
Your routine
iS ClinicalHydra-Cool Serum
Why it fits
A hydrating serum before moisturizer.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
iS Clinical Retinol+ Emulsion 1.0
iS Clinical Retinol+ Emulsion 1.0 is the strongest retinol in the range.
Encapsulated retinol and bakuchiol work on lines, texture and tone, while shea butter, squalane and ectoin keep skin comfortable.
For skin already used to retinol.
Benefits
- Softens the look of fine lines
- Refines texture
- Evens the look of tone
- Firmer-looking skin
Best for
Experienced retinol users
Master 0.3 before moving to 1.0.
How to use
- Evenings only, 2 to 3 pumps.
- Every 2 to 3 days for a week, then a week off; repeat.
- Sunscreen every morning.
- Not during pregnancy or breastfeeding.
Full Ingredient List
Water/Aqua/Eau, Glycerin, Squalane, Pentylene Glycol, Sodium Hyaluronate, Butyrospermum Parkii (Shea) Butter, Ectoin, Polysorbate 20, Glyceryl Citrate/Lactate/Linoleate/Oleate, Polyglyceryl-4 Cocoate, Polyglyceryl-3 Cocoate, Glyceryl Caprylate, Tocopherol, Retinol, Butylene Glycol, Triethanolamine, Carbomer, Phragmites Communis Extract, Poria Cocos Extract, Oryza Sativa (Rice) Bran Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Phosphatidylcholine, Chlorella Vulgaris Extract, Propanediol, Caprylic/Capric Triglyceride, Lecithin, Lactic Acid, Polysorbate 40, Helianthus Annuus (Sunflower) Extract, Bakuchiol, Phenoxyethanol, Polyacrylamide, C13-14 Isoalkane, Laureth-7, Tripeptide-1, Dextran, Ascorbic Acid, Colloidal Gold, Glutathione, Panthenol, Heptyl Undecylenate, C13-16 Isoalkane, Dipotassium Glycyrrhizate, Bidens Pilosa Extract, Elaeis Guineensis (Palm) Oil, Gossypium Herbaceum (Cotton) Seed Oil, Linum Usitatissimum (Linseed) Seed Oil, Glycine Soja (Soybean) Extract, Sodium Hydroxide, Disodium EDTA, Phenylpropanol, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Diisopropyl Adipate, Triethyl Citrate, Xanthan Gum, Sorbitol, Fragrance/Parfum.
Ingredients may be updated by the manufacturer. Please refer to the product packaging for the most current ingredient list.
Shipping & returns
For delivery and return information, view our policy.
A Maximum-Strength Encapsulated Retinol
iS Clinical Retinol+ Emulsion 1.0 is the strongest retinol in the range, for skin already comfortable with retinol. Encapsulated retinol and bakuchiol work on the look of fine lines, deeper wrinkles, rough texture and uneven tone, while squalane, shea butter, hyaluronic acid and ectoin keep skin comfortable. We recommend using it with guidance from our team or your skincare professional.
Benefits
- Softens the look of fine lines and deeper wrinkles
- Refines rough texture and blemish-prone skin
- Evens the look of tone and brightens
- Helps skin look firmer and more elastic
- Antioxidant care
How to Use
- In the evening, apply 2 to 3 pumps over the face.
- Use every 2 to 3 days for one week, take one week off, then repeat the cycle, or as directed by your skincare professional.
- Follow with moisturizer. Apply sunscreen every morning.
Loshen & Crem’s Recommendation
Start with Retinol+ Emulsion 0.3 if you are new to retinol. Some dryness or flaking is normal as skin adjusts. Do not use on the same night as peels or exfoliants. Do not use retinol if you are pregnant or breastfeeding; ask your healthcare provider.
Ingredients
- Retinol: Encapsulated with phosphatidylcholine for easier delivery.
- Bakuchiol: A botanical that supports smoothing.
- Shea Butter and Squalane: Comfort and nourish.
- Ectoin: Helps protect against environmental stress.
- Vitamin C, Glutathione and Copper Tripeptide: Antioxidant care and firmer-looking skin.
Full Ingredient List
Water/Aqua/Eau, Glycerin, Squalane, Pentylene Glycol, Sodium Hyaluronate, Butyrospermum Parkii (Shea) Butter, Ectoin, Polysorbate 20, Glyceryl Citrate/Lactate/Linoleate/Oleate, Polyglyceryl-4 Cocoate, Polyglyceryl-3 Cocoate, Glyceryl Caprylate, Tocopherol, Retinol, Butylene Glycol, Triethanolamine, Carbomer, Phragmites Communis Extract, Poria Cocos Extract, Oryza Sativa (Rice) Bran Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Phosphatidylcholine, Chlorella Vulgaris Extract, Propanediol, Caprylic/Capric Triglyceride, Lecithin, Lactic Acid, Polysorbate 40, Helianthus Annuus (Sunflower) Extract, Bakuchiol, Phenoxyethanol, Polyacrylamide, C13-14 Isoalkane, Laureth-7, Tripeptide-1, Dextran, Ascorbic Acid, Colloidal Gold, Glutathione, Panthenol, Heptyl Undecylenate, C13-16 Isoalkane, Dipotassium Glycyrrhizate, Bidens Pilosa Extract, Elaeis Guineensis (Palm) Oil, Gossypium Herbaceum (Cotton) Seed Oil, Linum Usitatissimum (Linseed) Seed Oil, Glycine Soja (Soybean) Extract, Sodium Hydroxide, Disodium EDTA, Phenylpropanol, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Diisopropyl Adipate, Triethyl Citrate, Xanthan Gum, Sorbitol, Fragrance/Parfum.
Ingredients may be updated by the manufacturer. Please refer to the product packaging for the most current ingredient list.
Frequently Asked Questions
0.3 or 1.0?
Start with 0.3. Move to 1.0 only once your skin is comfortable with regular retinol, ideally with guidance from our team.
Where can I buy iS Clinical Retinol+ Emulsion 1.0 in Canada?
iS Clinical Retinol+ Emulsion 1.0 is available from Loshen & Crem online across Canada and at our Edmonton, Alberta boutique.
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your order01 · Across Canada
A good thing, on its way.
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Retinol
Refines and smooths.
Bakuchiol
Supports smoothing.
Butyrospermum Parkii (Shea) Butter and Squalane
Comfort.
Ectoin
Comforts stressed-feeling skin.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore iS Clinical.
Find your place to begin.
Discover iS Clinical Retinol+ Emulsion 1.0 at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the iS Clinical collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.