Your routine
iS ClinicalSheald Recovery Balm
Why it fits
A rich moisturizer or targeted comfort balm.
iS Clinical Poly-Vitamin Serum
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Explore La Crem rewardsTired, dehydrated skin
A hydrating serum with vitamins B5, B3, A and E that smooths, refines the look of pores and revitalizes tired-looking skin.
Discover the formula & ingredientsPickup in Edmonton
Usually ready in 24 hours
Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Let’s talk about your skin and what belongs in your routine.
From our boutique to your door
Shipping, on usRegular $149+ · Priority $249+ CAD
Discover something newComplimentary samples with every order
30-day returnsUnopened products · View policy
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Selected with care.
iS Clinical
Poly-Vitamin Serum
Your ritual begins with the right choice.
$124.00 CAD
Taxes calculated at checkout.
The skincare focus
Vitamins, delivered.
A hydrating serum with vitamins B5, B3, A and E that smooths, refines the look of pores and revitalizes tired-looking skin.
Explore our ingredient glossaryiS Clinical
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Pantothenic Acid and Niacinamide
Vitamins B5 and B3.
Retinol and Alpha Tocopherol
Vitamins A and E.
Sodium Hyaluronate
Hydrates.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Explore another step in your face-care routine.
Your routine
iS ClinicalCleansing Complex
Why it fits
The cleansing step, before serums.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
iS Clinical Poly-Vitamin Serum
iS Clinical Poly-Vitamin Serum is a vitamin-rich hydrating serum.
Vitamins B5, B3, A and E, hyaluronic acid and amino acids hydrate and smooth.
Skin looks healthier, softer and more refined.
Benefits
- Hydrates
- Smooths and softens
- Refines the look of pores
- Evens the look of tone
Best for
Tired, dehydrated skin
How to use
- Apply sparingly after cleansing.
- A brief flush is normal.
- Follow with moisturizer and sunscreen.
- Contains retinol.
Full Ingredient List
Water/Aqua/Eau, Sodium Hyaluronate, Saccharum Officinarum (Sugar Cane) Extract, Zinc Sulfate, Pantothenic Acid, Niacinamide, Alpha Tocopherol, Retinol, Lysine, Glutamine, Vaccinium Myrtillus (Bilberry) Extract, Camellia Sinensis Leaf Extract (Green Tea), Phenoxyethanol.
Ingredients may be updated by the manufacturer. Please refer to the product packaging for the most current ingredient list.
Shipping & returns
For delivery and return information, view our policy.
A Hydrating Multi-Vitamin Serum
iS Clinical Poly-Vitamin Serum delivers vitamins B5 and B3 (niacinamide), A and E with hyaluronic acid, amino acids, sugarcane and bilberry. It hydrates, smooths and softens, helps refine the look of pores and even out tone, and brings back a healthier, revitalized look.
Benefits
- Hydrates and revitalizes
- Smooths and softens
- Helps refine the look of pores
- Evens the look of tone and blemishes
- Softens the look of fine lines
How to Use
- Apply sparingly to clean skin, smoothing over the face and neck.
- A brief, temporary flush can occur and is normal.
- Follow with moisturizer, and sunscreen every morning.
Loshen & Crem’s Recommendation
A lovely all-round serum for skin that looks tired or stressed. It contains retinol: introduce it gradually, and if you are pregnant or breastfeeding, ask your healthcare provider before use.
Full Ingredient List
Water/Aqua/Eau, Sodium Hyaluronate, Saccharum Officinarum (Sugar Cane) Extract, Zinc Sulfate, Pantothenic Acid, Niacinamide, Alpha Tocopherol, Retinol, Lysine, Glutamine, Vaccinium Myrtillus (Bilberry) Extract, Camellia Sinensis Leaf Extract (Green Tea), Phenoxyethanol.
Ingredients may be updated by the manufacturer. Please refer to the product packaging for the most current ingredient list.
Frequently Asked Questions
Why does my skin flush?
A brief, temporary flush can occur after application and fades quickly.
Where can I buy iS Clinical Poly-Vitamin Serum in Canada?
iS Clinical Poly-Vitamin Serum is available from Loshen & Crem online across Canada and at our Edmonton, Alberta boutique.
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your order01 · Across Canada
A good thing, on its way.
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Pantothenic Acid and Niacinamide
Vitamins B5 and B3.
Retinol and Alpha Tocopherol
Vitamins A and E.
Sodium Hyaluronate
Hydrates.
Lysine and Glutamine
Amino acids.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore iS Clinical.
Find your place to begin.
Discover iS Clinical Poly-Vitamin Serum at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the iS Clinical collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.