Your routine
Biologique RechercheLotion P50T
Why it fits
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsDry, dehydrated skin
An intensive, comforting lipid serum for skin that feels dry, tight and uncomfortable. Its blend of botanical oils forms a protective film that helps limit transepidermal water loss.
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Biologique Recherche
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The skincare focus
An intensive, comforting lipid serum for skin that feels dry, tight and uncomfortable. Its blend of botanical oils forms a protective film that helps limit transepidermal water loss.
Explore our ingredient glossaryBiologique Recherche
The ingredients behind this formula—and what they bring to your skin.
Vaccinium Macrocarpon (Cranberry) Seed Oil
A nourishing botanical oil that helps replenish surface lipids.
Hippophae Rhamnoides (Sea Buckthorn) Oils
Rich botanical oils that help comfort and soften dry-feeling skin.
Macadamia, Camellia Japonica & Sesame Seed Oils
Emollient oils that help smooth the skin and reduce the feeling of tightness.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Cleanse with the milk selected for your Skin Instant, apply your Lotion P50 and serums, then Crème Dermo-RL. Sérum T.E.W.L. follows the cream, in place of your usual finishing serum. Finish with sunscreen in the morning. These pairings are suggestions; your routine should be personalized to your Skin Instant.
Your routine
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.
Your routine
Sérum T.E.W.L. is designed to be applied after Crème Dermo-RL, adding a protective lipid film over the cream for skin that feels dry and tight.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Biologique Recherche Sérum T.E.W.L. is an intensive lipid serum for dry, dehydrated and lipid-deficient-feeling skin that feels tight and uncomfortable.
Its blend of botanical oils forms a protective film that helps limit transepidermal water loss (T.E.W.L.), helping the skin hold on to its moisture. It helps relieve the feeling of tightness and reduces the appearance of fine lines associated with dehydration.
Used after Crème Dermo-RL in place of your usual finishing serum, it is a great choice for those visiting or living in dry, cold climates.
We like to reach for Sérum T.E.W.L. during long stretches of cold, dry weather, or whenever the skin feels extremely dehydrated. It slips into the routine in place of the usual finishing serum, so nothing else needs to change. We also like that it brings a feeling of comfort immediately after application and throughout the day.
Dry, dehydrated skin
When the weather turns cold and dry, swap your usual finishing serum for Sérum T.E.W.L. rather than adding another layer.
COCO-CAPRYLATE/CAPRATE, SESAMUM INDICUM (SESAME) SEED OIL, APRICOT KERNEL OIL PEG-6 ESTERS, MACADAMIA TERNIFOLIA SEED OIL, CAMELLIA JAPONICA SEED OIL, VACCINIUM MACROCARPON (CRANBERRY) SEED OIL, HIPPOPHAE RHAMNOIDES OIL, HIPPOPHAE RHAMNOIDES SEED OIL, GOSSYPIUM HERBACEUM (COTTON) SEED OIL, ETHYLHEXYL PALMITATE, RASPBERRY SEED OIL/TOCOPHERYL SUCCINATE AMINOPROPANEDIOL ESTERS, OLEA EUROPAEA (OLIVE) FRUIT OIL, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, LUFFA CYLINDRICA SEED OIL, SUNFLOWER SEED OIL GLYCERIDES, SIMMONDSIA CHINENSIS (JOJOBA) SEED EXTRACT, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, SALICORNIA HERBACEA EXTRACT, UNDARIA PINNATIFIDA EXTRACT, CANANGA ODORATA FLOWER OIL, CITRUS AURANTIUM AMARA (BITTER ORANGE) FLOWER OIL, TOCOPHEROL, PHYTOSTEROLS, DATEM, CAPRYLIC/CAPRIC TRIGLYCERIDE, LINALOOL, LIMONENE, BENZYL BENZOATE, FARNESOL, GERANIOL, BENZYL SALICYLATE.
It stands for transepidermal water loss. The serum's botanical oils form a protective film that helps limit it, helping the skin hold on to its moisture.
Dry, dehydrated and lipid-deficient-feeling skin that feels tight and uncomfortable, especially in dry, cold climates.
After Crème Dermo-RL, in place of your usual finishing serum, over the face, neck and décolleté.
As an intensive course, 2 to 3 times a week, morning and/or evening, for about 28 days. It can also be used during long stretches of cold, dry weather.
4 drops for the face, neck and décolleté.
Yes. The ingredient list includes ylang-ylang and bitter orange flower oils as well as fragrance components such as linalool, limonene and geraniol. Check the full list if you are sensitive to fragrance ingredients.
Yes. The formula contains ingredients derived from macadamia. If you have a nut allergy, please book a consultation with one of our estheticians before purchasing.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
For delivery and return information, view our policy.
Biologique Recherche Sérum T.E.W.L. is an intensive lipid serum for dry, dehydrated and lipid-deficient-feeling skin that feels tight and uncomfortable.
Its blend of botanical oils forms a protective film that helps limit transepidermal water loss (T.E.W.L.), helping the skin hold on to its moisture. It helps relieve the feeling of tightness and reduces the appearance of fine lines associated with dehydration.
Used after Crème Dermo-RL in place of your usual finishing serum, it is a great choice for those visiting or living in dry, cold climates.
COCO-CAPRYLATE/CAPRATE, SESAMUM INDICUM (SESAME) SEED OIL, APRICOT KERNEL OIL PEG-6 ESTERS, MACADAMIA TERNIFOLIA SEED OIL, CAMELLIA JAPONICA SEED OIL, VACCINIUM MACROCARPON (CRANBERRY) SEED OIL, HIPPOPHAE RHAMNOIDES OIL, HIPPOPHAE RHAMNOIDES SEED OIL, GOSSYPIUM HERBACEUM (COTTON) SEED OIL, ETHYLHEXYL PALMITATE, RASPBERRY SEED OIL/TOCOPHERYL SUCCINATE AMINOPROPANEDIOL ESTERS, OLEA EUROPAEA (OLIVE) FRUIT OIL, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, LUFFA CYLINDRICA SEED OIL, SUNFLOWER SEED OIL GLYCERIDES, SIMMONDSIA CHINENSIS (JOJOBA) SEED EXTRACT, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, SALICORNIA HERBACEA EXTRACT, UNDARIA PINNATIFIDA EXTRACT, CANANGA ODORATA FLOWER OIL, CITRUS AURANTIUM AMARA (BITTER ORANGE) FLOWER OIL, TOCOPHEROL, PHYTOSTEROLS, DATEM, CAPRYLIC/CAPRIC TRIGLYCERIDE, LINALOOL, LIMONENE, BENZYL BENZOATE, FARNESOL, GERANIOL, BENZYL SALICYLATE.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
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Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
A nourishing botanical oil that helps replenish surface lipids.
Rich botanical oils that help comfort and soften dry-feeling skin.
Emollient oils that help smooth the skin and reduce the feeling of tightness.
Help protect the formula's lipids and support skin comfort.
Plant lipids that help support the skin's moisture barrier.
Botanical and marine extracts included in the formula's conditioning complex.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Biologique Recherche Sérum T.E.W.L. at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Biologique Recherche collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.