Your routine
CircadiaVitamin C Reversal Serum
Why it fits
An antioxidant serum for the whole face and neck, morning and evening. It goes on after cleansing and before moisturizer.

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Skincare Boutique & Facial Institute
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Explore La Crem rewardsUneven tone, dullness, blemish-prone skin
An evening serum with mandelic, tranexamic and azelaic acids that gently exfoliates and visibly brightens. It helps reduce the look of discoloration and redness while supporting the skin barrier.
Discover the formula & ingredientsPickup in Edmonton
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Circadia
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$120.00 CAD
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The skincare focus
An evening serum with mandelic, tranexamic and azelaic acids that gently exfoliates and visibly brightens. It helps reduce the look of discoloration and redness while supporting the skin barrier.
Explore our ingredient glossaryCircadia
The ingredients behind this formula—and what they bring to your skin.
Mandelic Acid
A gentle alpha hydroxy acid, at 5%, that exfoliates and refines the look of skin texture.
Tranexamic Acid
At 2%, helps reduce the look of discoloration for a more even tone.
Azelaic Acid
At 0.3%, helps visibly brighten and reduce the look of redness and blemishes.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
In the morning, Vitamin C Reversal Serum makes a natural partner for antioxidant support and hydration. If you also use vitamin A or another exfoliant, ask us how to alternate them so your skin stays comfortable.
Your routine
An antioxidant serum for the whole face and neck, morning and evening. It goes on after cleansing and before moisturizer.
Your routine
Exfoliating acids call for daily sun protection, so a mineral SPF every morning protects the brighter, more even look this serum works on overnight.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Circadia Serum 71 is an evening serum for skin that looks uneven, dull or prone to blemishes. It brings together three acids to gently exfoliate and visibly brighten: mandelic acid (5%), tranexamic acid (2%) and azelaic acid (0.3%).
Together they help reduce the look of discoloration, redness and blemishes, for skin that looks clearer and more even. CM-Glucan Forte helps support and comfort the skin barrier, and NeoDermyl® (copper lysinate/prolinate) helps support the look of firmer, denser, more resilient skin.
Because it contains exfoliating acids, wear a daily sunscreen while you use it.
Some skin looks uneven and tired but does not tolerate stronger exfoliants. Serum 71 is our answer for it: three acids working gently every evening, with barrier support built in. Used steadily, with sunscreen every morning, it lets tone look more even without putting your skin through a harsh reset.
Uneven tone, dullness, blemish-prone skin
Let your skin dry fully after cleansing before you apply it, for the most comfortable feel.
Aqua/Water, Propanediol, Mandelic Acid (5%), Butylene Glycol, Tranexamic Acid (2%), Phenoxyethanol, Sodium PCA, Hydroxyethylcellulose, Sodium Hydroxide, Azelaic Acid (0.3%), Glycerin, Magnesium Carboxymethyl Beta-Glucan (CM-Glucan Forte), Methylglucoside Phosphate, Copper Lysinate/Prolinate (NeoDermyl®), Alcohol, Sodium Hydroxide.
In the evening, after cleansing. Smooth several drops over the face and neck, then follow with your moisturizer.
Yes. It contains exfoliating acids, so wear a daily sunscreen.
That is often why we suggest it. It is designed to gently resurface and visibly brighten without irritation.
We like Circadia Vitamin C Reversal Serum for antioxidant support and hydration, followed by sunscreen.
Book a consultation so we can look at your skin together and adjust your routine.
For delivery and return information, view our policy.
A brightening evening serum for uneven tone, dullness and blemish-prone skin
Circadia Serum 71 is an evening serum that combines mandelic, tranexamic and azelaic acids to gently exfoliate and visibly brighten the skin. It helps reduce the look of discoloration and redness while supporting the skin barrier. CM-Glucan Forte and NeoDermyl® (copper lysinate/prolinate) help support the look of firmer, denser, more resilient skin.
In the evening after cleansing, apply several drops to your fingertips and smooth over the face and neck. Avoid contact with the eyes. Because this serum contains exfoliating acids, wear a daily sunscreen.
We often suggest Serum 71 for skin that looks uneven or uninspired but does not tolerate stronger exfoliants. Use it at night, then in the morning apply Circadia Vitamin C Reversal Serum for antioxidant support and hydration, followed by a sunscreen such as Circadia Circa-Shield Mineral Sunscreen SPF 30 to protect your results. If you are working on persistent discoloration, book a consultation so we can look at your skin together.
Aqua/Water, Propanediol, Mandelic Acid (5%), Butylene Glycol, Tranexamic Acid (2%), Phenoxyethanol, Sodium PCA, Hydroxyethylcellulose, Sodium Hydroxide, Azelaic Acid (0.3%), Glycerin, Magnesium Carboxymethyl Beta-Glucan (CM-Glucan Forte), Methylglucoside Phosphate, Copper Lysinate/Prolinate (NeoDermyl®), Alcohol, Sodium Hydroxide.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
A gentle alpha hydroxy acid, at 5%, that exfoliates and refines the look of skin texture.
At 2%, helps reduce the look of discoloration for a more even tone.
At 0.3%, helps visibly brighten and reduce the look of redness and blemishes.
Helps support and comfort the skin barrier.
Helps support the look of firm, dense skin.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Circadia Serum 71 at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Circadia collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
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