Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsWinner of the 2023 Aestheticians' Choice Awards - Favorite Retinol Serum
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From our boutique to your door
Selected with care.
Osmosis
Your ritual begins with the right choice.
$175.00 CAD
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The skincare focus
Winner of the 2023 Aestheticians' Choice Awards - Favorite Retinol Serum
Explore our ingredient glossaryOsmosis
The ingredients behind this formula—and what they bring to your skin.
Hyaluronic acid
A moisture-binding ingredient that helps skin feel hydrated and look smoother.
Niacinamide
A form of vitamin B3 used in skin care to support the moisture barrier and a more even-looking complexion.
Beta-glucan
A skin-conditioning ingredient that helps maintain a comfortable, hydrated skin feel.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Explore another step in your face-care routine.
Your routine
Prep your skin with the best daily moisturizer that delivers light, soothing hydration with a refreshing citrus scent. This natural moisturizer for dry skin features jojoba seed oil, lemon oil, and hyaluronic acid to hydrate your skin and help support the skin's barrier.
Your routine
This remarkable formula pampers your skin with nature's finest!
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Winner of the 2023 Aestheticians' Choice Awards - Favorite Retinol Serum
Spoil your skin with our most advanced, age-defying formula. Using the highest potency of our liposomal retinaldehyde, Renew offers sun-safe, barrier-protecting technology. Designed to increase nutrient delivery to the skin's surface enhanced by a professional-grade delivery system that delivers 9 scientifically validated, firming ingredients and 7 potent antioxidants.
Water, Niacinamide, Phosphatidylcholine, Glycerin, Pentylene Glycol, Cyclodextrin, Asiaticoside, Palmitoyl Tripeptide-38, Dipeptide-6, Retinal, Ectoin, Caprooyl Tetrapeptide-3, Thioctic Acid, Chlorella Vulgaris Extract, Epilobium Angustifolium Flower/Leaf/Stem Extract, Sodium Hyaluronate, Lactic Acid, Beta-Glucan, Fulvic Acid, Hydroxyproline, Santalum Austrocaledonicum (Sandalwood) Wood Oil, Rubus Chamaemorus (Cloud Berry) Seed Oil, Hamamelis Virginiana (Witch Hazel) Water, Dimethyl Sulfone, Pogostemon Cablin (Patchouli) Oil, Lavandula Angustifolia (Lavender) Oil, Lonicera Caprifolium (Honeysuckle) Flower Extract, Lonicera Japonica (Honeysuckle) Flower Extract, Dextran, Hydroxypropyl Cyclodextrin, Alcohol Denat., Citric Acid, Xanthan Gum, Sodium Hydroxide, Alcohol, Potassium Sorbate, Benzyl Alcohol.
*all-natural/tout naturel
For delivery and return information, view our policy.
Winner of the 2023 Aestheticians' Choice Awards - Favorite Retinol Serum
Spoil your skin with our most advanced, age-defying formula. Using the highest potency of our liposomal retinaldehyde, Renew offers sun-safe, barrier-protecting technology. Designed to increase nutrient delivery to the skin's surface enhanced by a professional-grade delivery system that delivers 9 scientifically validated, firming ingredients and 7 potent antioxidants.
Shake well. Apply 2 pumps or the desired amount on clean skin in the morning and evening. Follow with additional serum(s) and moisturizer if needed.
Please note that the deluxe trial-size item is shipped without a box containing the ingredient list. Therefore, the Osmosis policy is to stamp "not for resale" on the container.
Water, Niacinamide, Phosphatidylcholine, Glycerin, Pentylene Glycol, Cyclodextrin, Asiaticoside, Palmitoyl Tripeptide-38, Dipeptide-6, Retinal, Ectoin, Caprooyl Tetrapeptide-3, Thioctic Acid, Chlorella Vulgaris Extract, Epilobium Angustifolium Flower/Leaf/Stem Extract, Sodium Hyaluronate, Lactic Acid, Beta-Glucan, Fulvic Acid, Hydroxyproline, Santalum Austrocaledonicum (Sandalwood) Wood Oil, Rubus Chamaemorus (Cloud Berry) Seed Oil, Hamamelis Virginiana (Witch Hazel) Water, Dimethyl Sulfone, Pogostemon Cablin (Patchouli) Oil, Lavandula Angustifolia (Lavender) Oil, Lonicera Caprifolium (Honeysuckle) Flower Extract, Lonicera Japonica (Honeysuckle) Flower Extract, Dextran, Hydroxypropyl Cyclodextrin, Alcohol Denat., Citric Acid, Xanthan Gum, Sodium Hydroxide, Alcohol, Potassium Sorbate, Benzyl Alcohol.
*all-natural/tout naturel
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
A moisture-binding ingredient that helps skin feel hydrated and look smoother.
A form of vitamin B3 used in skin care to support the moisture barrier and a more even-looking complexion.
A skin-conditioning ingredient that helps maintain a comfortable, hydrated skin feel.
A moisture-binding ingredient that contributes to a soft, conditioned skin feel.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Renew MD at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Osmosis collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
Curious about…
Our team can help you find another option suited to your skin and routine.
Need help choosing? Ask our team.