Your routine
mesoesteticHydracream Fusion
Why it fits
Balancing, anti-pollution cleansing facial cream-oil. It provides nourishment and hydration to the skin, leaving it beautifully smooth.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsFor experienced skincare users. One of the most potent dark-spot treatments available for home use. Please speak with our team before starting.
Discover the formula & ingredientsPickup currently unavailable in Edmonton
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Selected with care.
mesoestetic
Your ritual begins with the right choice.
$150.00 CAD
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The skincare focus
For experienced skincare users. One of the most potent dark-spot treatments available for home use. Please speak with our team before starting.
Explore our ingredient glossarymesoestetic
The ingredients behind this formula—and what they bring to your skin.
Tranexamic acid
helps visibly reduce dark spots that appear with triggers such as sun exposure and hormonal changes.
Tyr control complex
the combination of kojic acid with an innovative peptide and an amino acid helps visibly fade dark spots and even the look of skin tone.
Niacinamide
helps even the look of skin tone and reduce the appearance of dark spots.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Explore another step in your face-care routine.
Your routine
Balancing, anti-pollution cleansing facial cream-oil. It provides nourishment and hydration to the skin, leaving it beautifully smooth.
Your routine
Intensive concentrate with a calming effect and high skin tolerance. It soothes sensitive and sensitized skin and visibly reduces localized redness and the look of irritation. With antioxidant and rebalancing ingredients for balanced, resilient-looking skin.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
For experienced skincare users. One of the most potent dark-spot treatments available for home use. Please speak with our team before starting.
Dark-spot correcting cream for daily use that acts gradually on visible dark spots to give a more uniform-looking skin tone. Helps prevent the look of new dark spots and keep them from reappearing. Quickly absorbed light gel cream texture.
Call us on 780-722-9086 or email us at info@loshen.ca. Our Skin Experts will guide you to the perfect selection of this advanced cosmeceutical product.
Aqua, Isodecyl Neopentanoate, Tranexamic Acid, Niacinamide, Jojoba Esters, Glycerin, Isostearyl Alcohol, Butylene Glycol, Polymethylsilsesquioxane, Sodium Citrate, Helianthus annuus Seed Wax, Butylene Glycol Cocoate, Caprylic/Capric Triglyceride, Isononyl Isononanoate, Polyacrylate Crosspolymer-6, Lactic acid, Kojic acid, Argania spinosa Kernel Oil, Salicylic acid, Aminoethylphosphinic acid, Glycogen, Acetyl Glycyl beta-Alanine, Acacia decurrens Flower Wax, Polyglycerin-3, Polyacrylate-13, Dimethicone, Polyisobutene, Ethylhexylglycerin, Sorbitan Isostearate, Ethylcellulose, Polysorbate 20, Sodium Hydroxide, Citric acid, Sodium Metabisulfite, BHT, Disodium EDTA, Phenoxyethanol, Parfum.
Mesoestetic products are designed to deliver real, visible results on dark spots and uneven tone. These are powerful, professional-grade treatments—not your everyday skincare—and they require a tailored approach to ensure safety and effectiveness. While we respect recommendations from other professionals, please note that if you purchase Mesoestetic from Loshen & Crem without a direct recommendation from our own team, we cannot accept returns, refunds, or credits in the event of sensitivity or an allergic reaction. Our professionals take great care to assess each client’s skin needs, knowing that these active ingredients, though transformative, may not be suitable for everyone. As an authorized retailer, Loshen & Crem provides only the latest formulations to ensure you’re getting the best results possible. Thank you for trusting Loshen & Crem with your skincare journey. We’re here to support you with expertise, care, and a commitment to helping you achieve safe, beautiful results.
For delivery and return information, view our policy.
For experienced skincare users. One of the most potent dark-spot treatments available for home use. Please speak with our team before starting.
Dark-spot correcting cream for daily use that acts gradually on visible dark spots to give a more uniform-looking skin tone. Helps prevent the look of new dark spots and keep them from reappearing. Quickly absorbed light gel cream texture.
Call us on 780-722-9086 or email us at info@loshen.ca. Our Skin Experts will guide you to the perfect selection of this advanced cosmeceutical product.
Precautions for use
Wash hands after application to avoid direct contact with eyes and mucous membranes, if necessary, rinse with plenty of water. Keep out of the reach of children.
Aqua, Isodecyl Neopentanoate, Tranexamic Acid, Niacinamide, Jojoba Esters, Glycerin, Isostearyl Alcohol, Butylene Glycol, Polymethylsilsesquioxane, Sodium Citrate, Helianthus annuus Seed Wax, Butylene Glycol Cocoate, Caprylic/Capric Triglyceride, Isononyl Isononanoate, Polyacrylate Crosspolymer-6, Lactic acid, Kojic acid, Argania spinosa Kernel Oil, Salicylic acid, Aminoethylphosphinic acid, Glycogen, Acetyl Glycyl beta-Alanine, Acacia decurrens Flower Wax, Polyglycerin-3, Polyacrylate-13, Dimethicone, Polyisobutene, Ethylhexylglycerin, Sorbitan Isostearate, Ethylcellulose, Polysorbate 20, Sodium Hydroxide, Citric acid, Sodium Metabisulfite, BHT, Disodium EDTA, Phenoxyethanol, Parfum.
Mesoestetic products are designed to deliver real, visible results on dark spots and uneven tone. These are powerful, professional-grade treatments—not your everyday skincare—and they require a tailored approach to ensure safety and effectiveness.
While we respect recommendations from other professionals, please note that if you purchase Mesoestetic from Loshen & Crem without a direct recommendation from our own team, we cannot accept returns, refunds, or credits in the event of sensitivity or an allergic reaction. Our professionals take great care to assess each client’s skin needs, knowing that these active ingredients, though transformative, may not be suitable for everyone.
As an authorized retailer, Loshen & Crem provides only the latest formulations to ensure you’re getting the best results possible.
Thank you for trusting Loshen & Crem with your skincare journey. We’re here to support you with expertise, care, and a commitment to helping you achieve safe, beautiful results.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
helps visibly reduce dark spots that appear with triggers such as sun exposure and hormonal changes.
the combination of kojic acid with an innovative peptide and an amino acid helps visibly fade dark spots and even the look of skin tone.
helps even the look of skin tone and reduce the appearance of dark spots.
offers protection from the oxidation produced by natural light and the radiation induced by technological sources (electromagnetic waves (REM), blue light (HEV)).
Curious about your ingredients?
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Expert guidance. A considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Melan Tran3x Gel Cream at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the mesoestetic collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
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