Your routine
Biologique RechercheLotion P50T
Why it fits
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsDull, tired-looking skin needing hydration
A light, intensely moisturizing cream that visibly revitalizes the skin and brightens the complexion, for a fresher, renewed-looking glow.
Discover the formula & ingredientsPickup in Edmonton
Usually ready in 24 hours
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Selected with care.
Biologique Recherche
Your ritual begins with the right choice.
$232.00 CAD
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The skincare focus
A light, intensely moisturizing cream that visibly revitalizes the skin and brightens the complexion, for a fresher, renewed-looking glow.
Explore our ingredient glossaryBiologique Recherche
The ingredients behind this formula—and what they bring to your skin.
Sodium Hyaluronate
Helps attract and hold water for lasting hydration.
Ascorbyl Glucoside & Tocopherol
Antioxidants (vitamin C and E derivatives) that support a brighter-looking complexion and help protect the skin from environmental stress.
Hydrolyzed Silk
Helps soften and smooth the skin.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Cleanse with the milk selected for your Skin Instant, apply the Lotion P50 selected for your Skin Instant, then your Quintessential Serums before Crème Grand Millésime. For a complete ritual, pair the cream with Sérum Grand Millésime, a finishing serum used as one of the last steps, and add sunscreen in the morning. These pairings are suggestions; your routine should be personalized to your Skin Instant.
Your routine
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.
Your routine
Sérum Grand Millésime is the serum of the same Grand Millésime ritual: pairing the two gives a complete routine focused on a revitalized, radiant-looking complexion.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Biologique Recherche Crème Grand Millésime is a revitalizing and hydrating cream that brightens the complexion. It is so light that it doesn't sit on the surface or clog pores.
This multi-function, intensely moisturizing cream improves the look of skin elasticity while helping preserve the skin's natural defenses, for a fresher, renewed-looking complexion. Enriched with moisturizing ingredients, it provides intense, lasting hydration to the epidermis to restore comfort and suppleness.
The new formula helps prevent the appearance of visible signs of aging and fatigue. A new antioxidant platform enhances its hydrating and brightening effects for visibly revitalized skin.
Crème Grand Millésime proves that an intensely moisturizing cream does not have to feel heavy. We love its lightness: it hydrates deeply without sitting on the surface. It is the cream we think of when the complexion looks tired and dull and needs a fresher, more radiant look. Paired with Sérum Grand Millésime, it completes a ritual built around radiance and visible revitalization.
Dull, tired-looking skin needing hydration
A hazelnut-sized amount is enough for the face, neck and décolleté: this cream is light, so there is no need to layer on more for intense hydration.
Water (Aqua), Caprylic/Capric Triglyceride, Coco-Caprylate/Caprate, Propylene Glycol, Glycerin, Pentaerythrityl Distearate, Cetyl Alcohol, Xylitylglucoside, 1,2-Hexanediol, Butyrospermum Parkii (Shea) Butter, Jojoba Esters, Cucumis Sativus (Cucumber) Fruit Extract, Helianthus Annuus (Sunflower) Seed Wax, Medicago Sativa (Alfalfa) Extract, Hydrolyzed Silk, Myrtus Communis Leaf Extract, Allium Cepa (Onion) Bulb Extract, Centella Asiatica Extract, Commiphora Myrrha Resin Extract, Hamamelis Virginiana (Witch Hazel) Bark/Leaf Extract, Hypericum Perforatum Flower/Leaf/Stem Extract, Sophora Japonica Flower Extract, Anhydroxylitol, Ascorbyl Glucoside, Xylitol, Sodium Hyaluronate, Glyceryl Stearates, Caramel, Tocopherol, Sodium Stearoyl Glutamate, Stearyl Alcohol, Polyacrylate Crosspolymer-6, Propanediol, Polyglycerin-3, Caprylyl Glycol, Sodium Hydroxide, Potassium Sorbate, Sodium Benzoate.
No. It is so light that it doesn't sit on the surface or clog pores, while still providing intense, lasting hydration.
After the Lotion P50 selected for your Skin Instant and your Quintessential Serums, as the cream step.
A hazelnut-sized amount over the face, neck and décolleté.
No. Avoid the eye contour.
For a complete ritual, pair it with Sérum Grand Millésime. This is a suggestion; your esthetician will personalize your routine.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
For delivery and return information, view our policy.
Biologique Recherche Crème Grand Millésime is a revitalizing and hydrating cream that brightens the complexion. It is so light that it doesn't sit on the surface or clog pores.
This multi-function, intensely moisturizing cream improves the look of skin elasticity while helping preserve the skin's natural defenses, for a fresher, renewed-looking complexion. Enriched with moisturizing ingredients, it provides intense, lasting hydration to the epidermis to restore comfort and suppleness.
The new formula helps prevent the appearance of visible signs of aging and fatigue. A new antioxidant platform enhances its hydrating and brightening effects for visibly revitalized skin.
Water (Aqua), Caprylic/Capric Triglyceride, Coco-Caprylate/Caprate, Propylene Glycol, Glycerin, Pentaerythrityl Distearate, Cetyl Alcohol, Xylitylglucoside, 1,2-Hexanediol, Butyrospermum Parkii (Shea) Butter, Jojoba Esters, Cucumis Sativus (Cucumber) Fruit Extract, Helianthus Annuus (Sunflower) Seed Wax, Medicago Sativa (Alfalfa) Extract, Hydrolyzed Silk, Myrtus Communis Leaf Extract, Allium Cepa (Onion) Bulb Extract, Centella Asiatica Extract, Commiphora Myrrha Resin Extract, Hamamelis Virginiana (Witch Hazel) Bark/Leaf Extract, Hypericum Perforatum Flower/Leaf/Stem Extract, Sophora Japonica Flower Extract, Anhydroxylitol, Ascorbyl Glucoside, Xylitol, Sodium Hyaluronate, Glyceryl Stearates, Caramel, Tocopherol, Sodium Stearoyl Glutamate, Stearyl Alcohol, Polyacrylate Crosspolymer-6, Propanediol, Polyglycerin-3, Caprylyl Glycol, Sodium Hydroxide, Potassium Sorbate, Sodium Benzoate.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Helps attract and hold water for lasting hydration.
Antioxidants (vitamin C and E derivatives) that support a brighter-looking complexion and help protect the skin from environmental stress.
Helps soften and smooth the skin.
Botanical extracts that bring a fresh, soothing feel.
Help nourish and restore comfort without heaviness.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Biologique Recherche Crème Grand Millésime at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Biologique Recherche collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.