Your routine
Skinbetter ScienceTrio Luxe Moisture Treatment
Why it fits
Trio Luxe Moisture Treatment seals in the hydration from Ampra and adds rich comfort over AlphaRet.
Skinbetter Science Volumizing & Resurfacing Duo
Tax excluded. Shipping calculated at checkout
Your ritual, rewarded 220 estimated La Crem points
Your ritual, rewarded. Choose your La Crem tier to estimate your points.
Estimated on eligible spend before tax, shipping and discounts. Your account confirms the final balance.
Explore La Crem rewardsLoss of fullness, fine lines, uneven texture
A two-step duo for skin that looks less full, with fine lines and uneven texture. Ampra helps skin look plumper and more defined, while AlphaRet refines texture and softens the look of lines overnight.
Discover the formula & ingredientsPickup in Edmonton
Usually ready in 24 hours
Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
Wait for your ready-for-pickup email before visiting.
Visit the boutiqueNeed expert guidance?
Let’s talk about your skin and what belongs in your routine.
From our boutique to your door
Shipping, on usRegular $149+ · Priority $249+ CAD
Discover something newComplimentary samples with every order
30-day returnsUnopened products · View policy
On its way to youTrack your order
Selected with care.
Skinbetter Science
Volumizing & Resurfacing Duo
Your ritual begins with the right choice.
$220.00 CAD
Taxes calculated at checkout.
The skincare focus
Fuller-looking skin meets smoother texture.
A two-step duo for skin that looks less full, with fine lines and uneven texture. Ampra helps skin look plumper and more defined, while AlphaRet refines texture and softens the look of lines overnight.
Explore our ingredient glossarySkinbetter Science
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Sodium Thioctoyl/Formoyl Hyaluronate (Ampra)
HYAsync technology, two weights of hyaluronic acid bonded with alpha lipoic acid, for a visibly plumper look.
Palmitoyl Tripeptide-38 (Ampra)
A peptide that helps skin look smoother and fuller.
Ethyl Lactyl Retinoate (AlphaRet)
AlphaRet technology, a retinoid bonded to lactic acid, for smoother-looking texture and softer-looking lines.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Follow with a moisturizer such as Trio and a daily sunscreen. Avoid other retinoids, peel pads or exfoliating toners while you introduce AlphaRet.
Your routine
Skinbetter ScienceAlto Advanced Defense and Repair Serum
Why it fits
An antioxidant serum, applied after cleansing and before treatments and moisturizer.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
Skinbetter Science Volumizing & Resurfacing Duo
The Skinbetter Science Volumizing & Resurfacing Duo pairs Ampra Volumizing Macro HA Serum (15 ml) with AlphaRet Overnight Cream (15 ml), with a travel pouch. Two patented technologies, each with a clear role.
Ampra is a silky serum built around HYAsync technology, which bonds two weights of hyaluronic acid with alpha lipoic acid, plus a peptide and teff extract. It helps skin look plumper, smoother and more contoured. AlphaRet Overnight Cream combines a retinoid bonded to lactic acid with glycolic acid, peptides and ceramides to smooth the look of rough texture, fine lines and wrinkles.
Use Ampra morning and evening, and AlphaRet in the evening after Ampra. Because AlphaRet contains a retinoid and alpha hydroxy acids, introduce it gradually and wear a daily sunscreen.
Why we love it
Skin can look less full and more textured at the same time, and these concerns need different tools. Ampra focuses on visible plumpness and contour, while AlphaRet brings resurfacing to the evening. Each formula stays in its lane, which makes the ritual easy to follow. We like it for clients who want hydration and renewal in one focused routine.
Benefits
- Helps skin look plumper and fuller
- Improves the look of facial contours
- Smooths the look of rough texture
- Softens the look of fine lines and wrinkles
- Supports hydrated, supple-feeling skin
Best for
Loss of fullness, fine lines, uneven texture
Press Ampra in with your palms along the cheekbones and jawline before AlphaRet goes on.
How to use
- Morning: on clean, dry skin, apply 1-2 pumps of Ampra to the face.
- Follow with moisturizer if needed and finish with a daily sunscreen.
- Evening: after cleansing, apply 1-2 pumps of Ampra.
- Follow with 1-2 pumps of AlphaRet in a thin layer, avoiding the eye area.
- Add moisturizer if your skin needs more comfort.
- If your skin is new to retinoids, start AlphaRet every second or third evening and build up.
- Wear a daily sunscreen, since AlphaRet contains alpha hydroxy acids.
- Avoid contact with eyes.
Precautions
Full Ingredient List
Ampra Volumizing Macro HA Serum:
Aqua/Water/Eau, Glycerin, Isocetyl Stearoyl Stearate, Niacinamide, Pentylene Glycol, Jojoba Esters, Hydrolyzed Yeast Extract, Squalane, Glycol Palmitate, Cetyl Alcohol, Lecithin, Sodium Methyl Stearoyl Taurate, Sodium Thioctoyl/Formoyl Hyaluronate, Palmitoyl Tripeptide-38, Hydrolyzed Eragrostis Tef Seed Extract, Hydrolyzed Sodium Hyaluronate, Hydroxypropyl Cyclodextrin, Tetrasodium Glutamate Diacetate, Citric Acid, Xanthan Gum, Polyglucuronic Acid, Cetyl Hydroxyethylcellulose, Tocopherol, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol
AlphaRet Overnight Cream:
Aqua/Water/Eau, Sodium Glycolate, Glycolic Acid, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide NP, Hyaluronic Acid, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii (Shea) Butter, Allantoin Glycyrrhetinic Acid, Sodium PCA, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Tromethamine, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, Titanium Dioxide (CI 77891)
Frequently Asked Questions
What is in the duo?
Ampra Volumizing Macro HA Serum (15 ml) and AlphaRet Overnight Cream (15 ml), with a travel pouch.
Do I use both products morning and night?
No. Ampra can be used morning and evening; AlphaRet is for the evening only.
What does volumizing mean for a serum?
It describes a visibly plumper, fuller-looking appearance. A topical serum is not the same as an injectable filler.
Do I need sunscreen?
Yes. AlphaRet contains alpha hydroxy acids, so wear a daily sunscreen and limit sun exposure.
Can I use it while pregnant or breastfeeding?
AlphaRet contains a retinoid. Speak with your physician before use if you are pregnant, breastfeeding or planning a pregnancy.
Shipping & returns
For delivery and return information, view our policy.
Fuller-looking skin meets smoother texture.
A two-step duo for skin that looks less full, with fine lines and uneven texture. Ampra helps skin look plumper and more defined, while AlphaRet refines texture and softens the look of lines overnight.
The Skinbetter Science Volumizing & Resurfacing Duo pairs Ampra Volumizing Macro HA Serum (15 ml) with AlphaRet Overnight Cream (15 ml), with a travel pouch. Two patented technologies, each with a clear role.
Ampra is a silky serum built around HYAsync technology, which bonds two weights of hyaluronic acid with alpha lipoic acid, plus a peptide and teff extract. It helps skin look plumper, smoother and more contoured. AlphaRet Overnight Cream combines a retinoid bonded to lactic acid with glycolic acid, peptides and ceramides to smooth the look of rough texture, fine lines and wrinkles.
Use Ampra morning and evening, and AlphaRet in the evening after Ampra. Because AlphaRet contains a retinoid and alpha hydroxy acids, introduce it gradually and wear a daily sunscreen.
Benefits
- Helps skin look plumper and fuller
- Improves the look of facial contours
- Smooths the look of rough texture
- Softens the look of fine lines and wrinkles
- Supports hydrated, supple-feeling skin
Why we love it
Skin can look less full and more textured at the same time, and these concerns need different tools. Ampra focuses on visible plumpness and contour, while AlphaRet brings resurfacing to the evening. Each formula stays in its lane, which makes the ritual easy to follow. We like it for clients who want hydration and renewal in one focused routine.
How to use
- Morning: on clean, dry skin, apply 1-2 pumps of Ampra to the face.
- Follow with moisturizer if needed and finish with a daily sunscreen.
- Evening: after cleansing, apply 1-2 pumps of Ampra.
- Follow with 1-2 pumps of AlphaRet in a thin layer, avoiding the eye area.
- Add moisturizer if your skin needs more comfort.
- If your skin is new to retinoids, start AlphaRet every second or third evening and build up.
- Wear a daily sunscreen, since AlphaRet contains alpha hydroxy acids.
- Avoid contact with eyes.
Key ingredients
- Sodium Thioctoyl/Formoyl Hyaluronate (Ampra): HYAsync technology, two weights of hyaluronic acid bonded with alpha lipoic acid, for a visibly plumper look.
- Palmitoyl Tripeptide-38 (Ampra): A peptide that helps skin look smoother and fuller.
- Ethyl Lactyl Retinoate (AlphaRet): AlphaRet technology, a retinoid bonded to lactic acid, for smoother-looking texture and softer-looking lines.
- Glycolic Acid (AlphaRet): An alpha hydroxy acid that helps refine the look of rough texture.
- Niacinamide and Squalane (both): Support the barrier and keep the skin soft and comfortable.
- Hydrolyzed Sodium Hyaluronate (Ampra): A small-fragment hyaluronic acid that hydrates the upper layers of the skin.
Full ingredient list
Ampra Volumizing Macro HA Serum
Aqua/Water/Eau, Glycerin, Isocetyl Stearoyl Stearate, Niacinamide, Pentylene Glycol, Jojoba Esters, Hydrolyzed Yeast Extract, Squalane, Glycol Palmitate, Cetyl Alcohol, Lecithin, Sodium Methyl Stearoyl Taurate, Sodium Thioctoyl/Formoyl Hyaluronate, Palmitoyl Tripeptide-38, Hydrolyzed Eragrostis Tef Seed Extract, Hydrolyzed Sodium Hyaluronate, Hydroxypropyl Cyclodextrin, Tetrasodium Glutamate Diacetate, Citric Acid, Xanthan Gum, Polyglucuronic Acid, Cetyl Hydroxyethylcellulose, Tocopherol, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol
AlphaRet Overnight Cream
Aqua/Water/Eau, Sodium Glycolate, Glycolic Acid, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide NP, Hyaluronic Acid, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii (Shea) Butter, Allantoin Glycyrrhetinic Acid, Sodium PCA, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Tromethamine, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, Titanium Dioxide (CI 77891)
Please refer to the packaging of your product for the most up-to-date ingredient list.
Important information
Sun sensitivity: This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing and limit sun exposure while using this product and for a week afterwards.
Pregnancy and breastfeeding: This product contains a topical retinoid. If you are pregnant, breastfeeding or planning a pregnancy, speak with your physician before use.
Caution: For external use only. Avoid contact with eyes; if contact occurs, rinse thoroughly with water. If irritation persists, discontinue use and consult a physician.
Discover Skinbetter Science at Loshen & Crem
Explore Skinbetter Science at Loshen & Crem, our skin-health boutique and facial studio in Edmonton. We ship across Canada, and our team is happy to help you find the right routine.
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your order01 · Across Canada
A good thing, on its way.
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Sodium Thioctoyl/Formoyl Hyaluronate (Ampra)
HYAsync technology, two weights of hyaluronic acid bonded with alpha lipoic acid, for a visibly plumper look.
Palmitoyl Tripeptide-38 (Ampra)
A peptide that helps skin look smoother and fuller.
Ethyl Lactyl Retinoate (AlphaRet)
AlphaRet technology, a retinoid bonded to lactic acid, for smoother-looking texture and softer-looking lines.
Glycolic Acid (AlphaRet)
An alpha hydroxy acid that helps refine the look of rough texture.
Niacinamide and Squalane (both)
Support the barrier and keep the skin soft and comfortable.
Hydrolyzed Sodium Hyaluronate (Ampra)
A small-fragment hyaluronic acid that hydrates the upper layers of the skin.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore Skinbetter Science.
Find your place to begin.
Discover Skinbetter Science Volumizing & Resurfacing Duo at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Skinbetter Science collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.