Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsUltra-comforting, fragrance-free cream for sensitive and reactive skin
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For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
Selected with care.
Esthederm
Your ritual begins with the right choice.
$92.00 CAD
Taxes calculated at checkout.
The skincare focus
Ultra-comforting, fragrance-free cream for sensitive and reactive skin
Explore our ingredient glossaryEsthederm
The ingredients behind this formula—and what they bring to your skin.
Olive
An olive-derived ingredient used in skin-conditioning formulas. See the full list for its exact form.
Glycerin
A humectant that helps attract moisture and keep skin feeling hydrated.
Pentylene glycol
Helps retain moisture and contributes to a smooth, lightweight formula.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Explore another step in your face-care routine.
Your routine
A 3-in-1 micellar water that effortlessly removes makeup, cleanses, and tones in one calming sweep. Infused with Esthederm’s signature Cellular Water and soothing botanicals, this multitasking formula respects the skin’s natural balance while leaving it fresh, soft, and comforted. No rinsing required—just a radiant reset.
Your routine
A targeted protective cream designed to support skins prone to pigmentation while enhancing a more even, natural-looking tan. Formulated with Esthederm’s advanced sun care technology, this formula helps regulate melanin distribution, visibly reduce the appearance of dark spots, and protect the skin from UV-induced damage. The texture is smooth and comfortable, leaving the skin hydrated, balanced, and visibly more uniform over time.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Ultra-comforting, fragrance-free cream for sensitive and reactive skin
The Calming Biomimetic Cream is an ultra-soothing formula designed to comfort and rebalance sensitive or reactive skin. With its biomimetic composition and smooth, creamy texture, this treatment helps the skin “rest” by restoring its natural defenses and improving tolerance over time. Enriched with olive oil, rhamnose, and marine extracts, it delivers lasting hydration while reducing feelings of discomfort and tightness. Skin feels soothed, supple, and more resilient with every application.
Aqua/Water/Eau, Caprylic/Capric Triglyceride, Glycerin, Dicaprylyl Ether, Isostearyl Isostearate, Olea Europaea (Olive) Fruit Oil, C10-18 Triglycerides, Cetyl Alcohol, C12-16 Alcohols, Pentylene Glycol, Arachidyl Alcohol, Tocopheryl Acetate, Behenyl Alcohol, Hydrogenated Lecithin, Palmitic Acid, Rhamnose, Leuconostoc/Radish Root Ferment Filtrate, Arachidyl Glucoside, Xanthan Gum, 1,2-Hexanediol, Caprylyl Glycol, Creatine, Sodium Citrate, Salix Nigra (Willow) Bark Extract, Citric Acid, Laminaria Ochroleuca Extract, Hydrolyzed Sweet Almond Protein, Propylene Glycol, Alcohol, Sodium Benzoate, Tris(Tetramethylhydroxypiperidinol) Citrate, Carnosine, Disodium Adenosine Triphosphate, Tocopherol, Laminaria Digitata Extract, Phenoxyethanol, Superoxide Dismutase, Tromethamine.
For delivery and return information, view our policy.
Ultra-comforting, fragrance-free cream for sensitive and reactive skin
The Calming Biomimetic Cream is an ultra-soothing formula designed to comfort and rebalance sensitive or reactive skin. With its biomimetic composition and smooth, creamy texture, this treatment helps the skin “rest” by restoring its natural defenses and improving tolerance over time. Enriched with olive oil, rhamnose, and marine extracts, it delivers lasting hydration while reducing feelings of discomfort and tightness. Skin feels soothed, supple, and more resilient with every application.
Apply morning and/or evening to the face, neck, and décolleté after cleansing.
Use daily as a soothing moisturizer or as an intensive recovery treatment when the skin feels irritated or sensitized.
For optimal relief and balance, pair with the Institut Esthederm Cellular Concentrate Fundamental Serum to strengthen skin tolerance and enhance hydration before applying the Calming Biomimetic Cream.
Aqua/Water/Eau, Caprylic/Capric Triglyceride, Glycerin, Dicaprylyl Ether, Isostearyl Isostearate, Olea Europaea (Olive) Fruit Oil, C10-18 Triglycerides, Cetyl Alcohol, C12-16 Alcohols, Pentylene Glycol, Arachidyl Alcohol, Tocopheryl Acetate, Behenyl Alcohol, Hydrogenated Lecithin, Palmitic Acid, Rhamnose, Leuconostoc/Radish Root Ferment Filtrate, Arachidyl Glucoside, Xanthan Gum, 1,2-Hexanediol, Caprylyl Glycol, Creatine, Sodium Citrate, Salix Nigra (Willow) Bark Extract, Citric Acid, Laminaria Ochroleuca Extract, Hydrolyzed Sweet Almond Protein, Propylene Glycol, Alcohol, Sodium Benzoate, Tris(Tetramethylhydroxypiperidinol) Citrate, Carnosine, Disodium Adenosine Triphosphate, Tocopherol, Laminaria Digitata Extract, Phenoxyethanol, Superoxide Dismutase, Tromethamine.
The care behind your order
A few helpful details, before your next delivery.
Track your orderDelivery
For delivery in Canada: Standard is $25 CAD below $149 CAD. Priority is $30 CAD below $249 CAD and free from $249 CAD on eligible orders. Adding an item excluded from free Priority removes free Priority for the entire order.
This selected item excludes the entire order from free Priority shipping in Canada. Standard is $25 CAD below $149 CAD and free from $149 CAD. A paid Priority upgrade is $30 CAD where available, including orders of $249 CAD or more.
Thresholds apply after discounts, before taxes and shipping. Product, ground-shipping and destination restrictions may apply. Available services and final charges appear at checkout.
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
An olive-derived ingredient used in skin-conditioning formulas. See the full list for its exact form.
A humectant that helps attract moisture and keep skin feeling hydrated.
Helps retain moisture and contributes to a smooth, lightweight formula.
An emollient that gives formulas a smooth glide and helps soften skin.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Esthederm Eau Cellulaire Calming Biomimetic Cream at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Esthederm collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
Curious about…
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