Your routine
BiodermaSensibio Defensive Serum
Why it fits
A soothing, hydrating serum applied after cleansing and before moisturizer.
Bioderma Sensibio Defensive
Tax excluded. Shipping calculated at checkout
Your ritual, rewarded 29 estimated La Crem points
Your ritual, rewarded. Choose your La Crem tier to estimate your points.
Estimated on eligible spend before tax, shipping and discounts. Your account confirms the final balance.
Explore La Crem rewardsSensitive, reactive skin
A lightweight, fragrance-free daily moisturizer for sensitive skin that feels dry or reactive. Carnosine, a peptide and red sage extract help soothe the skin and support its moisture barrier, leaving it soft and comfortable.
Discover the formula & ingredientsPickup in Edmonton
Usually ready in 24 hours
Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
Wait for your ready-for-pickup email before visiting.
Visit the boutiqueNeed expert guidance?
Let’s talk about your skin and what belongs in your routine.
From our boutique to your door
Shipping, on usRegular $149+ · Priority $249+ CAD
A little discoveryComplimentary samples with every order
30-day returnsUnopened products · View policy
On its way to youTrack your order
Selected with care.
Bioderma
Sensibio Defensive
Your ritual begins with the right choice.
$29.99 CAD
Taxes calculated at checkout.
The skincare focus
Everyday comfort for skin that reacts easily.
A lightweight, fragrance-free daily moisturizer for sensitive skin that feels dry or reactive. Carnosine, a peptide and red sage extract help soothe the skin and support its moisture barrier, leaving it soft and comfortable.
Explore our ingredient glossaryBioderma
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Carnosine
An antioxidant that helps protect the skin from daily stressors that contribute to dryness.
Palmitoyl Tetrapeptide-10
A peptide that helps support the skin barrier and its resilience.
Squalane
A lightweight emollient that helps soften the skin and support its moisture balance.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Cleanse first with Sensibio H2O Micellar Water. For extra comfort and hydration, layer Sensibio Defensive Serum underneath.
Your routine
BiodermaSensibio Eye+
Why it fits
A targeted eye care applied after cleansing and serum, before your moisturizer.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
Bioderma Sensibio Defensive
Bioderma Sensibio Defensive is a light, fresh moisturizer made for sensitive skin that feels dry, uncomfortable or reactive to everyday environmental stressors.
Carnosine and vitamin E (tocopherol) offer antioxidant support, palmitoyl tetrapeptide-10 helps support the skin barrier, and red sage extract helps soothe. Squalane and mango seed butter soften the skin and help keep its moisture balance.
The texture absorbs quickly and leaves the complexion soft, supple and comfortable. Fragrance-free, it is an easy everyday step and sits nicely under makeup.
Why we love it
Reactive skin often wants comfort without weight, and this is where Sensibio Defensive shines. It feels fresh going on, yet leaves the skin calm and supple for the rest of the day. We like it as the everyday moisturizer for anyone who finds richer creams too much. It also makes a smooth, unfussy base for makeup.
Benefits
- Helps soothe dry, sensitive skin
- Helps support the skin’s moisture barrier
- Antioxidant support with carnosine and vitamin E
- Leaves skin soft, supple and comfortable
- Lightweight texture that absorbs quickly
- Fragrance-free and paraben-free
Best for
Sensitive, reactive skin
When skin feels reactive, warm the cream between your fingertips and press it in rather than rubbing.
How to use
- Morning and evening.
- Apply to cleansed skin on the face and neck, ideally after a Sensibio cleanser.
- Massage gently until fully absorbed.
- In the morning, finish with a daily sunscreen.
Full Ingredient List
Aqua/Water/Eau, Glycerin, Dicaprylyl Ether, Propylheptyl Caprylate, Butylene Glycol, Glyceryl Stearate Citrate, Glycol Palmitate, Squalane, Sucrose Stearate, Mangifera Indica (Mango) Seed Butter, Pentylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Carnosine, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Mannitol, Xylitol, Tocopherol, Salvia Miltiorrhiza Flower/Leaf/Root Extract, Rhamnose, Glycine Soja (Soybean) Oil, Polysorbate 60, Sorbitan Isostearate, Palmitoyl Tetrapeptide-10. [BI 2012]
Frequently Asked Questions
Is Sensibio Defensive fragrance-free?
Yes. It is unfragranced and paraben-free, which suits sensitive skin.
Can I wear it under makeup?
Yes. The light texture absorbs quickly and makes a smooth makeup base.
Can I use it with Sensibio Defensive Serum?
Yes. Apply the serum first, then Sensibio Defensive to seal in comfort and hydration.
Do I still need sunscreen?
Yes. In the morning, finish with a daily sunscreen as the last step.
Shipping & returns
For delivery and return information, view our policy.
A lightweight, unfragranced daily moisturizer for sensitive skin that feels dry, uncomfortable or reactive to everyday environmental stressors. Sensibio Defensive helps soothe the skin, support its moisture barrier and defend it against daily aggressions. Its fresh texture absorbs quickly and leaves the complexion soft, supple and comfortable, making it an easy everyday step and a lovely makeup base.
Benefits:
- Helps soothe dry, sensitive skin
- Helps strengthen the skin’s moisture barrier
- Helps protect against daily aggressions that contribute to dryness
- Leaves skin hydrated, soft, supple and comfortable
- Lightweight texture that absorbs quickly; works well as a makeup base
- Unfragranced and paraben-free
How to Use:
- Apply morning and evening to the face and neck
- Use on cleansed skin, ideally after a Sensibio cleanser
- Gently massage until fully absorbed
- Follow with sunscreen in the morning
Loshen & Crem’s Recommendation:
The everyday moisturizer we suggest for skin that reacts easily but doesn’t want anything heavy. For extra comfort and hydration, layer Sensibio Defensive Serum underneath.
Ingredients:
Key Ingredients:
- Carnosine: An antioxidant that helps protect the skin from daily stressors that contribute to dryness.
- Palmitoyl Tetrapeptide-10: Helps support the skin barrier and its resilience.
- Salvia Miltiorrhiza Extract: Helps soothe the skin and support comfort.
- Squalane and Mango Seed Butter: Help soften and nourish the skin while supporting its moisture balance.
Full Ingredients List:
Aqua/Water/Eau, Glycerin, Dicaprylyl Ether, Propylheptyl Caprylate, Butylene Glycol, Glyceryl Stearate Citrate, Glycol Palmitate, Squalane, Sucrose Stearate, Mangifera Indica (Mango) Seed Butter, Pentylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Carnosine, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Mannitol, Xylitol, Tocopherol, Salvia Miltiorrhiza Flower/Leaf/Root Extract, Rhamnose, Glycine Soja (Soybean) Oil, Polysorbate 60, Sorbitan Isostearate, Palmitoyl Tetrapeptide-10. [BI 2012]
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your order01 · Across Canada
A good thing, on its way.
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Carnosine
An antioxidant that helps protect the skin from daily stressors that contribute to dryness.
Palmitoyl Tetrapeptide-10
A peptide that helps support the skin barrier and its resilience.
Squalane
A lightweight emollient that helps soften the skin and support its moisture balance.
Mango Seed Butter
Helps nourish and soften dry-feeling skin.
Salvia Miltiorrhiza (Red Sage) Extract
Helps soothe the skin and support its comfort.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore Bioderma.
Find your place to begin.
Discover Bioderma Sensibio Defensive at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Bioderma collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.