Your routine
Skinbetter ScienceAlto Advanced Defense and Repair Serum
Why it fits
Alto Advanced brings antioxidant care in the morning, so AlphaRet can focus on renewal at night.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsVisible lines, rough texture, uneven tone
A retinoid night cream for skin showing visible lines, rough texture and uneven tone. Patented AlphaRet technology pairs a retinoid with lactic acid, while glycolic acid, peptides and a moisturizing blend help skin look smoother and feel comfortable.
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Skinbetter Science
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The skincare focus
A retinoid night cream for skin showing visible lines, rough texture and uneven tone. Patented AlphaRet technology pairs a retinoid with lactic acid, while glycolic acid, peptides and a moisturizing blend help skin look smoother and feel comfortable.
Explore our ingredient glossarySkinbetter Science
The ingredients behind this formula—and what they bring to your skin.
Ethyl Lactyl Retinoate (AlphaRet)
Skinbetter Science's patented pairing of a retinoid and lactic acid, for smoother-looking skin.
Glycolic Acid
An alpha hydroxy acid that helps refine the look of rough texture.
Niacinamide
Vitamin B3, which helps hydration and the look of an even tone.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pair with Alto Advanced Defense and Repair Serum for antioxidant care and EyeMax AlphaRet Overnight Cream for the eye area. Avoid adding other retinoids or strong exfoliants on the same evening.
Your routine
Alto Advanced brings antioxidant care in the morning, so AlphaRet can focus on renewal at night.
Your routine
An evening eye treatment, applied after cleansing and before or after your face cream.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Skinbetter Science AlphaRet Overnight Cream is an evening cream that brings retinoid care and gentle exfoliation together in one step. At its centre is AlphaRet, a patented molecule that joins a retinoid with lactic acid, an alpha hydroxy acid.
Glycolic acid helps refine the look of rough texture, while peptides support a smoother, firmer-looking surface. Ceramide NP, squalane, niacinamide and hyaluronic acid help counter the dryness that often comes with retinoid use.
Vitamins C and E, coenzyme Q10 and green tea add antioxidant support. The result is an active night cream designed with comfort in mind, for skin that wants to look smoother and more even.
Retinoids work best when skin can tolerate them night after night. AlphaRet is built around that idea, pairing renewal with a generous moisturizing blend. It covers several visible concerns in a single evening step, which keeps a routine simple. We like it for anyone who wants smoother, more even-looking skin without a complicated regimen.
Visible lines, rough texture, uneven tone
If your skin feels dry while you adjust, apply your moisturizer first and AlphaRet on top to soften the experience.
Aqua/Water, Sodium Glycolate, Glycolic Acid, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide NP, Hyaluronic Acid, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii (Shea) Butter, Allantoin Glycyrrhetinic Acid, Sodium PCA, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Tromethamine, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, Titanium Dioxide (CI 77891).
It contains a retinoid, ethyl lactyl retinoate, which differs from conventional retinol. A retinol percentage is not a useful way to describe its strength.
It is designed for nightly use once your skin is comfortable. Start a few evenings a week if you are new to retinoids.
No. Use EyeMax AlphaRet Overnight Cream, which is formulated for the eye area.
Yes. It contains a retinoid and alpha hydroxy acids, so wear sunscreen every day and for a week after you stop.
It contains a topical retinoid. Speak with your physician before use if you are pregnant, breastfeeding or planning a pregnancy.
For delivery and return information, view our policy.
A retinoid night cream for skin showing visible lines, rough texture and uneven tone. Patented AlphaRet technology pairs a retinoid with lactic acid, while glycolic acid, peptides and a moisturizing blend help skin look smoother and feel comfortable.
Skinbetter Science AlphaRet Overnight Cream is an evening cream that brings retinoid care and gentle exfoliation together in one step. At its centre is AlphaRet, a patented molecule that joins a retinoid with lactic acid, an alpha hydroxy acid.
Glycolic acid helps refine the look of rough texture, while peptides support a smoother, firmer-looking surface. Ceramide NP, squalane, niacinamide and hyaluronic acid help counter the dryness that often comes with retinoid use.
Vitamins C and E, coenzyme Q10 and green tea add antioxidant support. The result is an active night cream designed with comfort in mind, for skin that wants to look smoother and more even.
Retinoids work best when skin can tolerate them night after night. AlphaRet is built around that idea, pairing renewal with a generous moisturizing blend. It covers several visible concerns in a single evening step, which keeps a routine simple. We like it for anyone who wants smoother, more even-looking skin without a complicated regimen.
Aqua/Water, Sodium Glycolate, Glycolic Acid, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide NP, Hyaluronic Acid, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii (Shea) Butter, Allantoin Glycyrrhetinic Acid, Sodium PCA, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Tromethamine, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, Titanium Dioxide (CI 77891).
Please refer to the packaging of your product for the most up-to-date ingredient list.
Sun sensitivity: This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing and limit sun exposure while using this product and for a week afterwards.
Pregnancy and breastfeeding: This product contains a topical retinoid. If you are pregnant, breastfeeding or planning a pregnancy, speak with your physician before use.
Caution: For external use only. Avoid contact with eyes; if contact occurs, rinse thoroughly with water. If irritation persists, discontinue use and consult a physician.
Explore Skinbetter Science at Loshen & Crem, our skin-health boutique and facial studio in Edmonton. We ship across Canada, and our team is happy to help you find the right routine.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Skinbetter Science's patented pairing of a retinoid and lactic acid, for smoother-looking skin.
An alpha hydroxy acid that helps refine the look of rough texture.
Vitamin B3, which helps hydration and the look of an even tone.
A lightweight lipid similar to skin's own oils that helps soften dryness.
A ceramide that helps support the skin's moisture barrier.
Curious about your ingredients?
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Expert guidance. A considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Skinbetter Science AlphaRet Overnight Cream at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Skinbetter Science collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
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