

Biologique Recherche Sérum Iso-Placenta
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A targeted serum for blemish-prone skin and the visible marks a breakout leaves behind. It helps reduce the look of recent and older post-blemish marks, soothe the look of redness and refine uneven texture.
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Regular $149+
Priority $249+
Régulière dès 149 $
Prioritaire dès 249 $
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Biologique Recherche Sérum Iso-Placenta
30 ml
Loshen & Crem
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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At a glance
- Step
- Serum, after Lotion P50
- When
- Daily
- Texture
- Fluid serum, fully absorbed
- Suits
- Blemish-prone skin with post-blemish marks
Choose options


Product details
A closer look.
Biologique Recherche Iso-Placenta is a facial serum created specifically for blemish-prone skin and the visible traces that can remain after a breakout. It helps reduce the appearance of both recent and older post-blemish marks, soothe the look of redness and refine uneven-looking texture for a smoother, more even-looking complexion. At its heart is Biologique Recherche's Biomimetic Placenta, an ingredient complex designed to reproduce key elements associated with human placenta. The current INCI does not list human placenta: the formula combines botanical extracts, peptides, amino-acid derivatives, ferment extracts and skin-conditioning ingredients. An active blemish and the mark it leaves are not the same concern. Rather than focusing on active oil, Iso-Placenta is centred on the visible aftermath of blemishes, the stage many routines forget. With consistent use, skin looks smoother, calmer and more even, and post-breakout marks become less noticeable. A cosmetic serum helps the look of flat marks; it cannot erase deep, indented or raised scars.
Why you’ll love it.
We recommend Iso-Placenta again and again because it addresses something so many blemish routines overlook: the breakout may be gone, but your skin doesn't look like it did before. We think of it when clients tell us the red mark stays forever, or that every breakout leaves something behind. It is not simply a breakout serum; it is the one we reach for when skin needs help looking smooth and even again after blemishes.
Pairs well with.
Ingredients, explained.
Explore the formulaFormula note 01
Camellia Sinensis Leaf Extract
A green tea-derived botanical extract that provides antioxidant and skin-conditioning support.
Formula note 02
Bacillus/Soybean Ferment Extract
A fermented ingredient included in the biomimetic, skin-conditioning complex.
Formula note 03
Oligopeptide-1, Oligopeptide-2 & Oligopeptide-3
Peptides included in the Biomimetic Placenta complex.
Formula note 04
Hexapeptide-11
A peptide included in the serum's targeted formulation.
Formula note 05
Acetyl Glutamine
An amino-acid derivative used in the formula's skin-conditioning complex.
Formula note 06
Sodium Hyaluronate
Helps support hydration and skin comfort.
The full formula
How to use
-
01
Apply after cleansing and the Lotion P50 selected for your Skin Instant, and before your moisturizer.
-
02
Apply approximately 1 ml to clean skin over the face, neck and décolleté.
-
03
Massage gently using light upward movements until completely absorbed.
-
04
It may also be applied more specifically to areas showing post-blemish marks, according to the needs of your Skin Instant.
-
05
If using several serums, apply your lighter, more fluid serums first.
-
06
For external use only.
Not sure if you're seeing a post-blemish mark, pigmentation or both? Ask us before choosing between Iso-Placenta and Sérum PIGM 400.
Your routine
Cleanse
Cleanse with the milk selected for your Skin Instant.
Lotion P50
Apply the Lotion P50 selected for your Skin Instant.
Biologique Recherche Lotion P50TSerum
If active blemishes and excess oil are also a concern, Complexe Iribiol may be part of the same routine; apply lighter formulas first.
Biologique Recherche Complexe IribiolThis product
Serum
About 1 ml massaged upward over the face, neck and décolleté, focusing on marked areas.
Biologique Recherche Sérum Iso-PlacentaCream
Finish with your moisturizer, such as Crème ISO-Placenta, if selected for your Skin Instant.
Biologique Recherche Crème Iso-PlacentaIn the morning
Apply a broad-spectrum sunscreen, always the last step.
For the marks a breakout leaves behind.
When to use it
Results build with consistent use.
Fluid and quickly absorbed.
Works well with
The Loshen & Crem experience
The pleasure is in the details.
Thoughtful skincare, from our Edmonton boutique to your daily ritual. Discover carefully chosen dermocosmetic brands, customized samples and the pleasure of a parcel prepared with care.
Knowledge behind the selection.
Our founder’s skincare education experience across Canada shapes how we explain ingredients, textures and the place of each product in a routine.
Samples with you in mind.
Customized samples to complement your order and introduce you to something worth discovering. A little curiosity, beautifully encouraged.
A gift to yourself.
Thoughtful preparation and finishing touches make receiving your skincare part of the pleasure.
A real boutique. A human point of view.
Loshen & Crem is a skincare boutique and facial studio in Edmonton. Our online selection carries that same considered approach.
Your questions, answered.
Is Iso-Placenta for active breakouts?
It focuses on the visible marks left after blemishes. If active blemishes, oiliness and excess sebum are the primary concerns, Complexe Iribiol may be more targeted.
Does Iso-Placenta help with scars?
It helps the look of flat post-blemish marks, redness and uneven microrelief. Deep, indented or raised scars are different: a cosmetic serum cannot erase them, and they should be assessed by a qualified professional.
Does it contain human placenta?
No human placenta is listed in the current ingredient list. Biologique Recherche describes its Biomimetic Placenta as designed to reproduce essential elements associated with human placenta.
Is it a brightening serum?
Its primary role is the look of post-blemish marks and uneven texture. The complexion may look brighter as marks fade, but it is not a general pigmentation serum; Sérum PIGM 400 is the dedicated choice for broader pigmentation.
Should I use the serum or Crème ISO-Placenta?
The serum is the targeted step, while Crème ISO-Placenta provides moisturizing and nourishing support. Depending on your Skin Instant, they can be used separately or together.
Does it contain fragrance ingredients?
The INCI lists fragrance allergens such as geraniol, limonene and linalool. If you have known sensitivities, review the full ingredient list or contact us before purchasing.
Skin Reaction Policy
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.

