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Calming & Barrier Serums

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29 products

Calming and barrier serums soothe reactive skin and help restore the skin barrier, the protective layer that keeps water in and irritants out. When that barrier is compromised, skin reacts to everything: redness, stinging, heat and sensitivity.

Who they're for

Sensitive, reactive and redness-prone skin, rosacea-prone skin, and skin that has been over-exfoliated, stressed by the weather or is recovering after a professional treatment.

Key ingredients to look for

Ceramides, niacinamide, panthenol, centella asiatica, azelaic acid, colloidal oat and microbiome-supporting ingredients such as pre- and postbiotics.

How to use

Apply morning and evening after cleansing, before moisturizer. While skin recovers, simplify your routine and pause strong actives such as acids and retinoids.

Expert insight from Loshen & Crem

Sensitivity is often a symptom, not a skin type. In our facial studio, a lot of the "sensitive skin" we see is a barrier that has been pushed too hard. Repair the barrier first, and the skin usually tolerates much more afterwards.

Frequently asked questions

Can a serum help with rosacea? Calming serums can make rosacea-prone skin more comfortable and less reactive. For diagnosis and medical treatment, see your physician or dermatologist.

How long does it take to repair the skin barrier? Most skin feels calmer within a few days, but rebuilding a resilient barrier usually takes several weeks of consistent, gentle care.

Rescue MD | Serum - Soothing | LOSHEN & CREM
Osmosis
Rescue MD Sale price$231.00 CAD
Rescue serum | Serum - Soothing | LOSHEN & CREM
Osmosis
Rescue serum Sale price$210.00 CAD
Serum Erythros | Serum - Rosacea | LOSHEN & CREM
Biologique Recherche
Serum Erythros Sale price$165.00 CAD
GlyMed Restoring Fulvic Elixir | Serum - Soothing | LOSHEN & CREM
PRO Biologique Recherche Serum Biosensible | Professional | LOSHEN & CREM
SIV™ Biome-Balancing Serum | Serum - Microbiome | LOSHEN & CREM
SIV™
SIV™ Biome-Balancing Serum Sale price$194.00 CAD
Sold outChrono-Calm Serum | Serum - Soothing | LOSHEN & CREM
Circadia
Chrono-Calm Serum Sale price$92.00 CAD
BIOJUVE™ Living Biome Essentials duo | Serum - Microbiome | LOSHEN & CREM
Sold outAugustinus Bader The Skin Infusion with Advanced TFC8® | Serum - Soothing | LOSHEN & CREM
BIOJUVE™ Biome Support Complex | Serum - Microbiome | LOSHEN & CREM
Remedy Serum | Serum - Soothing | LOSHEN & CREM
[comfort zone]
Remedy Serum Sale price$112.00 CAD
GlyMed Hemp soothing serum with micro silver | Serum - Soothing | LOSHEN & CREM
Vital Repair Serum | Serum - Soothing | LOSHEN & CREM
Nuori
Vital Repair Serum Sale price$95.00 CAD
Save 50%Avène Cicalfate+ Intensive Skin Recovery Serum | Serum - Soothing | LOSHEN & CREM
Save 10%Aqua Rescue Gel Lift | Serum - Soothing | LOSHEN & CREM
Aquafolia
Aqua Rescue Gel Lift Sale price$69.00 CAD
Bioderma Sensibio AR+ Bi-Serum | Serum - Anti-Redness | LOSHEN & CREM
Le Mieux Derma Relief Serum | Serum - Soothing | LOSHEN & CREM
Skinbetter Science Mystro Revive Renewing Serum | Serum - Barrier-replenishing | LOSHEN & CREM
SOS Neutralizing Serum | Serum - Soothing | LOSHEN & CREM
Aquafolia
SOS Neutralizing Serum Sale price$89.00 CAD
GlyMed Protective Skin Serum with Ceramides | Serum - Soothing | LOSHEN & CREM
Cold Plunge Facial Booster | Serum - Anti-Redness | LOSHEN & CREM
Osmosis
Cold Plunge Facial Booster Sale price$218.00 CAD
Alastin INhance Post-Injection Serum with TriHex Technology® | Serum - Soothing | LOSHEN & CREM
Save 10%CELLULAR Fusion Serum | Serum - Soothing | LOSHEN & CREM
Aquafolia
CELLULAR Fusion Serum Sale price$157.50 CAD
Skin Balance | Serum - Soothing | LOSHEN & CREM
mesoestetic®
Skin Balance Sale price$158.00 CAD
Sold outAvène Redness Expert Soothing Moisturizing Concentrated Cream | Serum - Anti-Redness | LOSHEN & CREM
Biophora Après Soothing Serum | Serum - Soothing | LOSHEN & CREM
RosaLieve® Redness Reducing Complex | Serum - Anti-Redness | LOSHEN & CREM
Sold outBioderma Sensibio Defensive Serum | Serum - Soothing | LOSHEN & CREM
GlyMed Essential Serum with Amino Acids | Serum - Barrier-replenishing | LOSHEN & CREM