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PERCENT SCIENCE Dexynol-16.3™ Cream
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Explore La Crem rewardsDexynol-16.3™ Cream is a lightweight, gel-type moisturizer developed to calm, balance, and visibly refine acne-prone and troubled skin. Powered by PERCENT SCIENCE’s patented biotechnology, this daily-use cream helps regulate excess sebum, soothe visible redness, and improve skin texture while delivering essential hydration without heaviness.
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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PERCENT SCIENCE
Dexynol-16.3™ Cream
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$74.25 CAD
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The skincare focus
PERCENT SCIENCE Dexynol-16.3™ Cream
Dexynol-16.3™ Cream is a lightweight, gel-type moisturizer developed to calm, balance, and visibly refine acne-prone and troubled skin. Powered by PERCENT SCIENCE’s patented biotechnology, this daily-use cream helps regulate excess sebum, soothe visible redness, and improve skin texture while delivering essential hydration without heaviness.
Explore our ingredient glossaryPERCENT SCIENCE
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Vitamin B12 (Cyanocobalamin)
Helps visibly calm irritation and reduce redness, supporting clearer-looking skin
Bioflavonoids
Help regulate sebum production, protect against environmental stressors, and refine skin texture
Allantoin
Helps soothe, repair, and support skin comfort in sensitive or irritated skin
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
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EltaMDUV Daily Broad-Spectrum SPF 40
Why it fits
A moisturizing daily sunscreen with hyaluronic acid for normal to dry skin
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
PERCENT SCIENCE Dexynol-16.3™ Cream
Balancing gel-cream for acne-prone & sensitive skin
Dexynol-16.3™ Cream is a lightweight, gel-type moisturizer developed to calm, balance, and visibly refine acne-prone and troubled skin. Powered by PERCENT SCIENCE’s patented biotechnology, this daily-use cream helps regulate excess sebum, soothe visible redness, and improve skin texture while delivering essential hydration without heaviness.
Its cooling, fast-absorbing texture makes it ideal for sensitive skin experiencing oil imbalance, congestion, or irritation. With consistent use, skin appears clearer, smoother, and more balanced.
Benefits
- Helps regulate excess sebum and reduce shine
- Visibly calms redness and irritation
- Supports clearer-looking, more balanced skin
- Helps refine the appearance of pores and rough texture
- Provides lightweight hydration without a greasy feel
- Suitable for sensitive and acne-prone skin
- 94% saw reduced appearance of active blemishes
- 91% reported skin felt clearer and more balanced
- 88% saw visibly reduced redness and irritation
- 82% noticed improved skin texture and smoothness
How to use
- After cleansing, apply an appropriate amount evenly over the face
- Use morning and evening
- Can be layered after Dexynol-16.3™ Booster Essence and Serum
Precautions
Full Ingredient List
Purified Water, 2,3-Butanediol, Glycerin, Dipropylene Glycol, Pentylene Glycol, Propanediol, Niacinamide, Coco-Caprylate/Caprate, Butylene Glycol, Raffinose, Green Tea Extract, Tocopherol, Bioflavonoid, Glucosyl Rutin, Rutin, Cyanocobalamin, Allantoin, Soybean Extract, Yuzu Oil, Hydrolyzed Jojoba Ester, Hydrogenated Olive Oil Unsaponifiables, Dipotassium Glycyrrhizate, Centella Asiatica Extract, Matricaria Flower Extract, Rhizome Root Extract, Rosemary Leaf Extract, Gold Extract, Adenosine, C9-12 Alkane, Castor Oil/IPDI Copolymer, Cetearyl Olivate, Dilinoleic Acid/Butanediol Copolymer, Ethylhexyl Palmitate, Hydrogenated Polyisobutene, Polyacrylate-13, Polyglyceryl-10 Distearate, Polyglyceryl-10 Laurate, Sodium Phytate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sorbitan Isostearate, Sorbitan Olivate, Stearic Acid, Carbomer, Triheptanoin, Tromethamine, Fragrance
Shipping & returns
For delivery and return information, view our policy.
Balancing gel-cream for acne-prone & sensitive skin
Dexynol-16.3™ Cream is a lightweight, gel-type moisturizer developed to calm, balance, and visibly refine acne-prone and troubled skin. Powered by PERCENT SCIENCE’s patented biotechnology, this daily-use cream helps regulate excess sebum, soothe visible redness, and improve skin texture while delivering essential hydration without heaviness.
Its cooling, fast-absorbing texture makes it ideal for sensitive skin experiencing oil imbalance, congestion, or irritation. With consistent use, skin appears clearer, smoother, and more balanced.
Benefits:
- Helps regulate excess sebum and reduce shine
- Visibly calms redness and irritation
- Supports clearer-looking, more balanced skin
- Helps refine the appearance of pores and rough texture
- Provides lightweight hydration without a greasy feel
- Suitable for sensitive and acne-prone skin
Proven Efficacy:
- 94% saw reduced appearance of active blemishes
- 91% reported skin felt clearer and more balanced
- 88% saw visibly reduced redness and irritation
- 82% noticed improved skin texture and smoothness
Sebum regulation efficacy confirmed through 4 weeks of internal testing and external human application testing. Hypoallergenic testing completed.
How to Use:
- After cleansing, apply an appropriate amount evenly over the face
- Use morning and evening
- Can be layered after Dexynol-16.3™ Booster Essence and Serum
Precautions:
- Discontinue use and consult a professional if irritation or abnormal reactions occur
- Avoid use on compromised or wounded skin
- Keep out of reach of children
- Store away from direct sunlight
Loshen & Crem’s Recommendation:
An excellent daily moisturizer for acne-prone, oily, or sensitive skin. Pair with Dexynol-16.3™ Booster Essence and Dexynol-16.3™ Serum for a complete balancing routine that supports clearer, calmer skin without stripping.
Ingredients:
Key Ingredients:
- Vitamin B12 (Cyanocobalamin): Helps visibly calm irritation and reduce redness, supporting clearer-looking skin
- Bioflavonoids: Help regulate sebum production, protect against environmental stressors, and refine skin texture
- Allantoin: Helps soothe, repair, and support skin comfort in sensitive or irritated skin
- Niacinamide (Vitamin B3): Helps balance oil, improve texture, and support a more even-looking complexion
Full Ingredients List:
Purified Water, 2,3-Butanediol, Glycerin, Dipropylene Glycol, Pentylene Glycol, Propanediol, Niacinamide, Coco-Caprylate/Caprate, Butylene Glycol, Raffinose, Green Tea Extract, Tocopherol, Bioflavonoid, Glucosyl Rutin, Rutin, Cyanocobalamin, Allantoin, Soybean Extract, Yuzu Oil, Hydrolyzed Jojoba Ester, Hydrogenated Olive Oil Unsaponifiables, Dipotassium Glycyrrhizate, Centella Asiatica Extract, Matricaria Flower Extract, Rhizome Root Extract, Rosemary Leaf Extract, Gold Extract, Adenosine, C9-12 Alkane, Castor Oil/IPDI Copolymer, Cetearyl Olivate, Dilinoleic Acid/Butanediol Copolymer, Ethylhexyl Palmitate, Hydrogenated Polyisobutene, Polyacrylate-13, Polyglyceryl-10 Distearate, Polyglyceryl-10 Laurate, Sodium Phytate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sorbitan Isostearate, Sorbitan Olivate, Stearic Acid, Carbomer, Triheptanoin, Tromethamine, Fragrance
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your order01 · Across Canada
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Collect in Edmonton.
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Speak with our boutique03 · Care you can count on
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Vitamin B12 (Cyanocobalamin)
Helps visibly calm irritation and reduce redness, supporting clearer-looking skin
Bioflavonoids
Help regulate sebum production, protect against environmental stressors, and refine skin texture
Allantoin
Helps soothe, repair, and support skin comfort in sensitive or irritated skin
Niacinamide (Vitamin B3)
Helps balance oil, improve texture, and support a more even-looking complexion
Curious about your ingredients?
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Expert guidance. A considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore PERCENT SCIENCE.
Find your place to begin.
Discover PERCENT SCIENCE Dexynol-16.3™ Cream at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the PERCENT SCIENCE collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.