



Creme PTO Metamorphique
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Formerly Crème ADN Métamorphique
firming – restructuring – tautening
Crème PTO Métamorphique is the next chapter in one of Biologique Recherche’s most iconic formulas. Formerly known as Crème ADN Métamorphique, this upgraded version builds on its firming legacy with new biomimetic actives and a clinically proven effect on facial ptosis.
Designed to support skin experiencing visible sagging, loss of tone, and a shift in facial contours, this cream works deeply to help restore structure and balance. With continued use, the skin appears firmer and more lifted, with a visibly redefined facial oval and neck contour.
It’s still the same philosophy: support the architecture of the skin, but with an even more modern formulation that absorbs beautifully and performs exceptionally.
Recommended for skin lacking firmness, tone, and definition—especially across the cheeks, jawline, and neck.
Benefits:
- firms and redefines the contours of the face and neck
- improves elasticity and lifts areas affected by ptosis
- stimulates collagen, elastin, and hyaluronic acid synthesis
- reinforces the skin’s underlying structure
- helps protect against external stressors
- hydrates and improves the skin’s natural regeneration process
How to use:
Apply a hazelnut-sized amount to clean skin of the face, neck, and décolleté. Massage gently with upward movements until completely absorbed. Use in the morning and/or evening.
Loshen & Crem's recommendations:
Clients transitioning from Crème ADN Métamorphique will find this new formulation slightly more fluid and fast-absorbing, with a similar sculpting result. For those using firming serums or tools like microcurrent, this cream pairs beautifully to reinforce the skin’s structural resilience.
Ingredients:
new formulation – Crème PTO Métamorphique
WATER (AQUA), COCO-CAPRYLATE/CAPRATE, CAPRYLIC/CAPRIC TRIGLYCERIDE, C10-18 TRIGLYCERIDES, SMITHSONITE EXTRACT, GLYCERIN, C12-16 ALCOHOLS, METHYLPROPANEDIOL, CETYL ALCOHOL, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, GLYCERYL STEARATE CITRATE, HYDROGENATED LECITHIN, PALMITIC ACID, TAPIOCA STARCH, SECALE CEREALE (RYE) SEED EXTRACT, PAEONIA ALBIFLORA ROOT EXTRACT, HELICHRYSUM STOECHAS EXTRACT, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, ADANSONIA DIGITATA PULP EXTRACT, PLANTAGO LANCEOLATA EXTRACT, LYCIUM BARBARUM FRUIT EXTRACT, VITIS VINIFERA (GRAPE) JUICE EXTRACT, ALTEROMONAS FERMENT EXTRACT, MALTODEXTRIN, TOCOPHEROL, LECITHIN, XANTHAN GUM, PENTAERYTHRITYL TETRASTEARATE, ISOMALT, 1,2-HEXANEDIOL, SORBITAN ISOSTEARATE, PROPANEDIOL, POLYSORBATE 60, CAPRYLYL GLYCOL, PHENYLPROPANOL, PHENETHYL ALCOHOL, SODIUM BENZOATE, POTASSIUM SORBATE
previous formulation – Crème ADN Métamorphique
WATER (AQUA), PROPYLENE GLYCOL, CETYL ALCOHOL, CAPRYLIC/CAPRIC TRIGLYCERIDE, STEARIC ACID, PALMITIC ACID, TRIETHANOLAMINE, LANOLIN OIL, DNA, NIACINAMIDE, PHENOXYETHANOL, YEAST EXTRACT (FAEX EXTRACT), ASCORBIC ACID, CARBOMER, BETULA ALBA BARK EXTRACT, EQUISETUM ARVENSE EXTRACT, CETEARYL ALCOHOL, ETHYLHEXYLGLYCERIN, HEDERA HELIX (IVY) LEAF/STEM EXTRACT, FUCUS VESICULOSUS EXTRACT, HYDROLYZED ELASTIN, CETEARETH-33, HYDROLYZED COLLAGEN, SORBIC ACID
BR Skin Reaction Policy 📄
At Loshen & Crem, we want to ensure you have the best experience possible with our brands. That's why we highly recommend having a consultation with one of our skin experts before purchasing any Biologique Recherche product.
In case of any reaction, they require images of the reaction, product, lot number on the bottom of the box OR product, and proof of an online consultation with one of our skin experts to ensure that they can assist you in the best possible way.
If you decide to purchase without a consultation and experience any reaction, we won't be able to provide a refund. However, we're always here to help you find the best products for your skin and answer any questions, so please don't hesitate to contact us.
Complimentary sample.
Free Express Shipping with orders over $189.99
Available at our Edmonton Boutique
Ship to Canada only
Pickup available at Loshen & Crem
Usually ready in 24 hours

Creme PTO Metamorphique
50 ml (ADN metamorphique)
Loshen & Crem
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
Returns & Refunds
At Loshen & Crem, we understand that sometimes, even the most carefully chosen product might not be "the one."
- Returns: You have 14 days from delivery to return any unopened and unused products in perfect condition—just as they arrived.
- Refunds: If your return reaches us within 30 days of purchase, you’ll have the choice between a refund or store credit (your preference, naturellement). After 30 days, store credit is your only option. Beyond 40 days, refunds and credits are no longer possible.
Shipping Policy
At Loshen & Crem, we take delivering your skincare treasures très seriously. From Canada to the U.S., we’re here to ensure your beauty cabinet is always well-stocked.
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Free Shipping:
- Canada: Complimentary EXPRESS shipping on orders over $189.99 CAD (after discounts and before taxes).
- United States: Complimentary EXPRESS shipping on orders over $250 USD. We are temporarily pausing USD payments at the moment. Apologies for the inconvenience, and thank you for your understanding!
- During our annual sales, enjoy free EXPEDITED shipping for orders over $250 CAD (or $350 USD).
- For smaller indulgences, shipping is $21.95 CAD within Canada and $30.95 USD to the U.S.
P.S. We ship to P.O. Boxes via Canada Post—but not during strikes. C’est compliqué.
Processing Time:
We aim to dispatch your order within 2 business days, though peak sales and payment verifications may require a touch more patience.
Please note that if you make any changes with the courier after the dispatch, our carrier will charge a $32 fee. In addition, we will have to withdraw the Free Express shipping option from your SkinSkinGlow points account. We appreciate your understanding.
Our processing time starts from the moment your order is successfully submitted and may take up to 2 business days to dispatch your order. However, please be aware that processing and handling time may be extended during peak sale periods. Before we can ship your order, we may need to hold your order for payment verification and confirm your details with your card issuer.
We will do our very best to minimize delays.
Shipping Rates & Delivery Times
Estimated Delivery Times (Canada):
- British Columbia & Alberta: 1–2 business days
- Manitoba & Saskatchewan: 1–2 business days
- Quebec & Ontario: 1–2 business days
- Atlantic Provinces: 1–3 business days
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United States: Delivery times vary by region:
- Zone 1: Eastern States – 3–4 business days
- Zone 2: Central States – 4–5 business days
- Zone 3: Western States – 5 business days
Remote areas may experience longer shipping times.
Please Note: Shipping windows are estimates and not guarantees. Delays may occur due to weather, traffic, or additional verification processes.
Shipping Address Details
For a smooth delivery, please provide all relevant information, including buzzer codes, directional suffixes (North, South, etc.), or special instructions.
- Address Changes: Once your package has left our warehouse, address updates cannot be made. If you need to make changes before dispatch, email us at info@loshen.ca with your order details.
- Carrier Fees: Any changes made with the courier after dispatch will incur a $32 CAD fee, and the Free Express Shipping option will be deducted from your La Crème Points account.
Tracking Your Order
All shipments include tracking information, so you can follow your package from our warehouse to your door. A confirmation email with your tracking number will be sent once your order is dispatched.
Damaged or Lost Packages
- Damaged Parcels: If your order arrives damaged, please contact us at info@loshen.ca with photos and details. We’ll work to resolve the issue promptly.
- Lost or Stolen Packages: If your package is marked "delivered" but hasn’t arrived, please contact the carrier directly to file a claim.
Tips to Avoid Lost or Stolen Packages:
- Opt for a signature upon receipt (required for orders over $350 CAD).
- Have your package delivered to your workplace.
- If you’re not home on the expected delivery date, ask a neighbor to receive your package.
Unclaimed Parcels
If your package is returned to us unclaimed, we’ll issue a refund minus a $23.95 CAD return shipping fee.
Free Samples
We believe every order deserves a little extra care! Expect 1–3 complimentary samples selected by our Skincare Specialists to perfectly complement your order.
Loyalty Rewards: La Crem Points
Earn La Crème Points with every purchase and redeem them for future orders. From time to time, we also offer Free Gifts With Purchase (GWP) for select brands, but these are available only while supplies last.
Clearance Items
Clearance items are FINAL SALE.
These products are offered at up to 75% off due to minor imperfections, nearing expiry dates (noted in descriptions), or other reasons. Returns, refunds, or credits are not available for these items.
At Loshen & Crem, we aim to deliver excellence at every step of your skincare journey, with care and a touch of elegance. Questions? Don’t hesitate to reach out—we’re always happy to assist!
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About Us
Loshen & Cream
Let's be clear, this is not about us. It's about you, it's about your skin health.
We are not your typical online skin care boutique. Although we are a virtual store, all of the experts behind Loshen & Crem are true professionals with an outstanding knowledge of the skin.
We choose the top skincare brands to provide you with the best options for healthy skin.
#Respectyourskin