Your routine
Biologique RechercheLotion P50T
Why it fits
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsLoss of firmness; all skin types
A next-generation bi-gel firming cream that helps skin look firmer, denser and more resilient overall. For skin showing a visible loss of firmness, fine lines and early to advanced visible signs of aging, including sensitive skin.
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Biologique Recherche
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The skincare focus
A next-generation bi-gel firming cream that helps skin look firmer, denser and more resilient overall. For skin showing a visible loss of firmness, fine lines and early to advanced visible signs of aging, including sensitive skin.
Explore our ingredient glossaryBiologique Recherche
The ingredients behind this formula—and what they bring to your skin.
Collagen complex (including Hydrolyzed Collagen)
Helps condition the skin and leaves it looking smoother and denser.
Glycosaminoglycans (including Sodium Hyaluronate)
Hydrate the upper layers of the epidermis for a plumper, smoother look.
Elasticity-focused ingredients
Help skin look firmer and feel more supple.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Cleanse with the milk selected for your Skin Instant, then apply the Lotion P50 selected for your Skin Instant. Layer serums focused on hydration, radiance or barrier support, such as Sérum Colostrum VG, then finish with Crème M.E.C. and, in the morning, sunscreen. These pairings are suggestions; your routine should be personalized to your Skin Instant.
Your routine
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.
Your routine
We like to pair Crème M.E.C. with a serum focused on hydration, and Sérum Colostrum VG is a hydrating serum that fits naturally in the serum step before it.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Biologique Recherche Crème M.E.C. is the brand's next-generation answer to visible signs of aging. It is designed not simply to target wrinkles, but to help skin look firmer, denser and more resilient overall.
This bi-gel cream was formulated around four families of ingredients inspired by the skin's own structure: collagen, elastin, glycosaminoglycans (GAGs) and glycoproteins. Hydrolyzed collagen helps condition the skin, while glycosaminoglycans, including hyaluronic acid, hydrate the upper layers of the epidermis for a plumper, smoother look.
With regular use, the skin looks firmer and more cohesive, and fine lines across the face, neck and décolleté look visibly smoother. It leaves the skin with a refined, smooth, "porcelain-like" finish and suits all skin types, including sensitive skin.
Crème M.E.C. is ideal for clients who want to care for the overall look of their skin, not just one line at a time. We love this cream for skin that needs global care rather than targeted line correction. We like to pair it with serums focused on hydration, radiance or barrier support for beautiful long-term results. It is a sophisticated daily cream for those investing in the future of their skin.
Loss of firmness; all skin types
Don't stop at the jawline: massage Crème M.E.C. down over the neck and décolleté too, where fine lines also show.
WATER (AQUA), GLYCERIN, COCO-CAPRYLATE/CAPRATE, CAPRYLIC/CAPRIC TRIGLYCERIDE, ISOSTEARYL ALCOHOL, MALTODEXTRIN, METHYLPROPANEDIOL, BUTYLENE GLYCOL COCOATE, LAUROYL LYSINE, UNDECANE, MEDICAGO SATIVA (ALFALFA) EXTRACT, SACCHARIDE HYDROLYSATE, POLYGLUTAMIC ACID, HAEMATOCOCCUS PLUVIALIS EXTRACT, SODIUM HYALURONATE, HYDROLYZED COLLAGEN, ETHYLCELLULOSE, LECITHIN, TOCOPHEROL, PENTYLENE GLYCOL, SORBITAN ISOSTEARATE, 1,2-HEXANEDIOL, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, TRIDECANE, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, POLYSORBATE 60, CAPRYLYL GLYCOL, PHENYLPROPANOL, SODIUM HYDROXIDE, SODIUM BENZOATE, POTASSIUM SORBATE.
Skin showing a visible loss of firmness and density, fine lines and early to advanced visible signs of aging, or skin lacking resilience, elasticity or "bounce".
Yes. It is recommended for all skin types, including sensitive skin.
It was formulated around four families of ingredients inspired by the skin's own structure: collagen, elastin, glycosaminoglycans (GAGs) and glycoproteins.
Morning and/or evening on clean skin, after your recommended Biologique Recherche serums. Add sunscreen every morning.
Crème M.E.C. is designed for clients seeking long-term visible improvement rather than a quick fix. With regular use, the skin looks firmer and more cohesive.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
For delivery and return information, view our policy.
Biologique Recherche Crème M.E.C. is the brand's next-generation answer to visible signs of aging. It is designed not simply to target wrinkles, but to help skin look firmer, denser and more resilient overall.
This bi-gel cream was formulated around four families of ingredients inspired by the skin's own structure: collagen, elastin, glycosaminoglycans (GAGs) and glycoproteins. Hydrolyzed collagen helps condition the skin, while glycosaminoglycans, including hyaluronic acid, hydrate the upper layers of the epidermis for a plumper, smoother look.
With regular use, the skin looks firmer and more cohesive, and fine lines across the face, neck and décolleté look visibly smoother. It leaves the skin with a refined, smooth, "porcelain-like" finish and suits all skin types, including sensitive skin.
WATER (AQUA), GLYCERIN, COCO-CAPRYLATE/CAPRATE, CAPRYLIC/CAPRIC TRIGLYCERIDE, ISOSTEARYL ALCOHOL, MALTODEXTRIN, METHYLPROPANEDIOL, BUTYLENE GLYCOL COCOATE, LAUROYL LYSINE, UNDECANE, MEDICAGO SATIVA (ALFALFA) EXTRACT, SACCHARIDE HYDROLYSATE, POLYGLUTAMIC ACID, HAEMATOCOCCUS PLUVIALIS EXTRACT, SODIUM HYALURONATE, HYDROLYZED COLLAGEN, ETHYLCELLULOSE, LECITHIN, TOCOPHEROL, PENTYLENE GLYCOL, SORBITAN ISOSTEARATE, 1,2-HEXANEDIOL, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, TRIDECANE, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, POLYSORBATE 60, CAPRYLYL GLYCOL, PHENYLPROPANOL, SODIUM HYDROXIDE, SODIUM BENZOATE, POTASSIUM SORBATE.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Helps condition the skin and leaves it looking smoother and denser.
Hydrate the upper layers of the epidermis for a plumper, smoother look.
Help skin look firmer and feel more supple.
Help skin look more cohesive and resilient.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book your consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Biologique Recherche Crème M.E.C. at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Biologique Recherche collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.