Your routine
Biologique RechercheCrème Biofixine
Why it fits
Crème Biofixine is a natural face-cream companion from the same Biofixine line, so the eye and lip contour and the rest of the face are cared for in the same spirit.

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Skincare Boutique & Facial Institute
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Explore La Crem rewardsDevitalized skin, visible signs of aging
A 2-in-1 cream for the eye and lip contour that smooths, hydrates and visibly reduces the look of wrinkles. Ideal for devitalized Skin Instants showing visible signs of aging.
Discover the formula & ingredientsPickup in Edmonton
Usually ready in 24 hours
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Biologique Recherche
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$195.00 CAD
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The skincare focus
A 2-in-1 cream for the eye and lip contour that smooths, hydrates and visibly reduces the look of wrinkles. Ideal for devitalized Skin Instants showing visible signs of aging.
Explore our ingredient glossaryBiologique Recherche
The ingredients behind this formula—and what they bring to your skin.
Complex of sugars, Hyaluronic acid, Shea butter and plant-based squalane
Moisturizing and lipid-restoring actives that restore hydration and comfort.
Watercress extract and Cassava extract
Smoothing and lifting actives for a smoother, lifted-looking contour.
Complex of proline, lysine and copper
A plumping active that helps the lips and contour look fuller.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Cleanse with the milk selected for your Skin Instant, then apply the Lotion P50 selected for your Skin Instant and any prescribed serums. Apply Crème Contour des Yeux et Lèvres Biofixine around the eyes and lips, then follow with your Biologique Recherche face cream, such as Crème Biofixine. Finish with sunscreen in the morning.
Your routine
Crème Biofixine is a natural face-cream companion from the same Biofixine line, so the eye and lip contour and the rest of the face are cared for in the same spirit.
Your routine
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Biologique Recherche Crème Contour des Yeux et Lèvres Biofixine smooths, relaxes and reduces the look of wrinkles around the eyes and lips. It was the first Biologique Recherche 2-in-1 product adapted to both the eye and mouth contour.
The formula revitalizes and restores hydration to these delicate areas, reinforcing the skin's barrier function. It lifts, tones and visibly increases skin elasticity, fills in the look of wrinkles around the mouth, and plumps up and reshapes the lips.
Grape juice extract enriched with δ-viniferin brings antioxidant properties that help protect the skin and help prevent visible signs of aging. The skin looks toned and firmer.
We love having one cream that cares for both the eye contour and the lip contour, two areas where fine lines often show first. It brings hydration and a smoother, firmer look without adding steps to the routine. We reach for it for devitalized Skin Instants that are starting to show visible signs of aging around the eyes and mouth. A small amount, gently massaged in, is all it takes.
Devitalized skin, visible signs of aging
A little goes a long way: use a small amount and massage gently until it is completely absorbed, without pulling the delicate skin.
WATER (AQUA), BUTYROSPERMUM PARKII (SHEA) BUTTER, PROPANEDIOL DICAPRYLATE, SQUALENE, GLYCERIN, PROPANEDIOL, CETYL ALCOHOL, GLYCERYL STEARATE, XYLITYLGLUCOSIDES, ANHYDROXYLITOL, XYLITOL, NASTURTIUM OFFICINALE EXTRACT, METHYLGLUCOSIDE PHOSPHATE, COPPER LYSINATE/PROLINATE, RHIZOBIAN GUM, SODIUM HYALURONATE, VITIS VINIFERA (GRAPE) JUICE EXTRACT, PALMITOYL OLIGOPEPTIDE, PALMITOYL TETRAPEPTIDE-7, PEG-75 STEARATE, METHYLPROPANEDIOL, BUTYLENE GLYCOL, TRIETHANOLAMINE, ETHYLHEXYLGLYCERIN, CETETH-20, STEARETH-20, HYDROLYZED MANIHOT ESCULENTA TUBER EXTRACT, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, CAPRYLHYDROXAMIC ACID, PHENOXYETHANOL, CARBOMER, SODIUM LACTATE, POLYSORBATE 20, CHLORPHENESIN.
Yes. It is a 2-in-1 cream adapted to both the eye contour and the lip contour.
It plumps up and reshapes the look of the lips and fills in the look of wrinkles around the mouth.
It is ideal for devitalized Skin Instants showing visible signs of aging around the eyes and lips.
Apply a small amount to cleansed skin and massage gently until completely absorbed.
A complex of sugars, hyaluronic acid, shea butter and plant-based squalane for hydration; watercress and cassava extracts for smoothing; a complex of proline, lysine and copper plus matrikines for plumping; and grape juice extract enriched with δ-viniferin for antioxidant protection.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
For delivery and return information, view our policy.
Biologique Recherche Crème Contour des Yeux et Lèvres Biofixine smooths, relaxes and reduces the look of wrinkles around the eyes and lips. It was the first Biologique Recherche 2-in-1 product adapted to both the eye and mouth contour.
The formula revitalizes and restores hydration to these delicate areas, reinforcing the skin's barrier function. It lifts, tones and visibly increases skin elasticity, fills in the look of wrinkles around the mouth, and plumps up and reshapes the lips.
Grape juice extract enriched with δ-viniferin brings antioxidant properties that help protect the skin and help prevent visible signs of aging. The skin looks toned and firmer.
WATER (AQUA), BUTYROSPERMUM PARKII (SHEA) BUTTER, PROPANEDIOL DICAPRYLATE, SQUALENE, GLYCERIN, PROPANEDIOL, CETYL ALCOHOL, GLYCERYL STEARATE, XYLITYLGLUCOSIDES, ANHYDROXYLITOL, XYLITOL, NASTURTIUM OFFICINALE EXTRACT, METHYLGLUCOSIDE PHOSPHATE, COPPER LYSINATE/PROLINATE, RHIZOBIAN GUM, SODIUM HYALURONATE, VITIS VINIFERA (GRAPE) JUICE EXTRACT, PALMITOYL OLIGOPEPTIDE, PALMITOYL TETRAPEPTIDE-7, PEG-75 STEARATE, METHYLPROPANEDIOL, BUTYLENE GLYCOL, TRIETHANOLAMINE, ETHYLHEXYLGLYCERIN, CETETH-20, STEARETH-20, HYDROLYZED MANIHOT ESCULENTA TUBER EXTRACT, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, CAPRYLHYDROXAMIC ACID, PHENOXYETHANOL, CARBOMER, SODIUM LACTATE, POLYSORBATE 20, CHLORPHENESIN.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Moisturizing and lipid-restoring actives that restore hydration and comfort.
Smoothing and lifting actives for a smoother, lifted-looking contour.
A plumping active that helps the lips and contour look fuller.
Plumping peptides that help smooth the look of wrinkles.
A protecting antioxidant active that helps prevent visible signs of aging.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Biologique Recherche Crème Contour des Yeux et Lèvres Biofixine at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Biologique Recherche collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.