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Calecim Professional Serum

Regular price $160.00 CADAfterpay

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Mature, sensitive skin

The most concentrated PTT-6® serum in the range: lightweight, fragrance-free, for firmer, smoother-looking skin.

Discover the formula & ingredients
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Pickup in Edmonton

Usually ready in 24 hours

Boutique details

Your Edmonton boutique.

5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada

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ORIBE travel trio & La Pochette

Calecim Professional · Gift with purchase

ORIBE travel trio & La Pochette

Any two CALECIM® products

ORIBE Gold Lust Dry Shampoo, Dry Heat Protection Spray and Nourishing Hair Oil in travel sizes, with La Pochette.

Before taxes and shipping. One gift per qualifying order, while quantities last. Cannot be combined with discount codes, rewards or other gift offers.

Need expert guidance?

Let’s talk about your skin and what belongs in your routine.

From our boutique to your door

Shipping, on usRegular $149+ · Priority $249+ CAD
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PTT-6®

The skincare focus

Concentrated, yet weightless.

The most concentrated PTT-6® serum in the range: lightweight, fragrance-free, for firmer, smoother-looking skin.

Explore our ingredient glossary

Calecim Professional

The formula, explained.

The ingredients behind this formula—and what they bring to your skin.

PTT-6®

PTT-6®

PTT-6® (Glycoproteins, Soluble Collagens, Albumin, Fibronectins): Calecim's signature protein complex for the look of firmer, smoother skin.

Ingredient imagery is illustrative. Explore the full ingredient list below.

Made to work together

Pairs beautifully.

View the range

Explore another step in your face-care routine.

Biologique Recherche Crème Hydravit’s

Your routine

Biologique RechercheCrème Hydravit’s

Regular price $129.00 CAD 50 ml
View product
Why it fits


The cream step for dehydrated, stressed skin, applied after Lotion P50 and your Sérums Quintessentiels. It brings lasting hydration and an immediate boost of radiance to finish the routine.

Biologique Recherche Lait VIP O₂

Your routine

Biologique RechercheLait VIP O₂

Regular price From $36.00 CAD 50 ml
View product
Why it fits


The cleansing step and the first step of your Biologique Recherche routine, removing makeup, sunscreen and impurities before your Lotion P50.

Worth knowing

The finer details.

A closer look at your skin, your routine and what goes into the formula.

Calecim Professional Serum

Calecim Professional Serum is the most concentrated PTT-6® formula in the range.

It helps skin look firmer, smoother and more even, while hyaluronic acid binds water for a temporarily plumper look.

Fragrance-free, with a texture so light it layers under anything.

Why we love it

Our pick when skin needs something more focused, without adding a heavy layer.

Benefits

  • Firmer-looking skin
  • Softens fine lines
  • Refines texture
  • Water binding & visible plumping

Best for

Mature, sensitive skin

How to use

  1. Apply about one pipette to clean skin.
  2. Let it absorb, then moisturize.
  3. Morning and/or evening. Sunscreen in the morning.

Precautions

Loshen tip: apply to slightly damp skin for easier spreading. In the evening, you can follow with Recovery Night Complex.
Do not apply over active breakouts.
After a professional treatment, follow your practitioner’s aftercare advice on when to use it.

Full Ingredient List

Aqua (Water), Hyaluronic Acid, Glycoproteins, 1,2-Hexanediol, Soluble Collagens, Albumin, Fibronectins.

Ingredients may be updated by the manufacturer. Please refer to the product packaging for the most current ingredient list.

Frequently Asked Questions

Why is the serum pink?

It contains a pH indicator, so the colour can range from yellow-orange to deeper pink from batch to batch. This is normal.

Why does it have a scent if it is fragrance-free?

The scent comes from the PTT-6® complex, not added fragrance, and can vary slightly between batches.

Is it vegan?

No. PTT-6® is animal-derived (red deer). It contains no human-derived material.

Can I use it during pregnancy?

Calecim states its products are safe during pregnancy and breastfeeding. We suggest checking with your doctor or midwife.

Professional Serum or Multi-Action Cream?

The serum is the most concentrated PTT-6® step; Multi-Action Cream is the everyday moisturizer. They layer well together, serum first.

Where can I buy Calecim Professional Serum in Canada?

Calecim Professional Serum is available from Loshen & Crem online across Canada and at our Edmonton, Alberta boutique.

Shipping & returns

For delivery and return information, view our policy.

Curious about your ingredients?

Explore La Matière
Abby offering a personal skincare consultation online from the Loshen boutique.

A little guidance. A more considered routine.

Your skin.
Our attention.

Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.

Talk through your skin, the products you already use and the questions on your mind with one of our facialists.

Book a consultation Just a product question? Ask us.
Personal guidance, in Edmonton or online.

The care behind your care

A place in your routine.
A team in your corner.

From your first question to your next replenishment, there’s a real person here to help.

01 Make sense of what you already use

You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.

Ask our team
02 Get to know your skin

Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.

Find your starting point
03 Keep the conversation going

A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.

We’re here to help

From our Edmonton boutique

Explore Calecim Professional.
Find your place to begin.

Discover Calecim Professional Serum at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Calecim Professional collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.

A little care, to keep.

Your ritual, beautifully noted.

The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.

  • 5 stars: 15 (83%)
  • 4 stars: 2 (11%)
  • 3 stars: 1 (6%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
M
Mrs
Game-Changer for my skin

After only a week of usage, I have noticed a visible improvement in my skin’s texture, hydration, and overall glow. My skin feels smoother, healthier, and more refreshed. I am impressed with the difference it has made. Calecim is a game-changer for my skin.

R
Rhonda
Impressed so far

I haven't been using it long enough for real results, but the mornings after the nights I have used it - my skin has been magical.

M
M.H

Super smoothing and soothing. Skin seems much stronger.

A
Adrianna
Worthwhile investment

After only 2 weeks it’s hard to know the longer results but I feel my skin has a more glowing appearance youthful feel- bit bouncier, healthier and less saggy . It hasn’t done any miraculous reduction of major lines but so far I’m satisfied this is making a difference. I’m eager to see how it goes after a few months and I trust the science behind this product .

K
Kim
I love it

I honestly really don’t know what it does but it makes my skin phenomenal and definitely helps with tightness and wrinkles for the price. I thought I’d try it once but now I’m hooked. I just buy the six pack. It’s like gold to

M
Miriam
Effective serum

i

I have been using Calecim products for few months now . I love everything that i have tried so far . This serum however is one of the best . I use it daily and can honestly see big improvement in my skin . One is improvement in my skin firmness all over my face around the mouth , jowls and also the neck area . The lines in my forehead is less visible . I am not complaining with the plumpness of my skin either . Marionette lines are less noticeable as well. The radiance of my skin and smoother texture and more even complexion . Expensive but worth it .

A
Allison
Calecim Serum

I have used one vial and starting the 2nd. I am very impressed that already I see results specifically around my eye area.

L
Lesley
So far so good, I think.

The bottle is so tiny and I'm amazed that after two weeks, I still have half a bottle left. I only use this once a day in my nighttime routine. I use it before the multi-action cream which is also potent so I can't credit this product alone for the changes I'm seeing. I've also read that it is most effective after micro-needling and laser procedures, so I'm not really sure how penetrative it is as a daily use serum. I also find it hard to spread on a dry face so I make sure my face is slightly damp when I apply it. I have no idea if this hinders the effect. It's extremely expensive so I think my future purchases will be creams, rather than this serum.

J
Julia
Love it

This serum is amazing. My skin looks so much more even after just 1 week! It takes a little time to figure out the best way to apply, so you don’t have to use too much.

C
Carla

Love this formula!! My skin actualky feels differnet when i out it on and compliments my skin care routine! I am a 57 year old woman who has tried so many different and pricey brands! This is my go to!!

K
KD
For Bulletproof Skin

This product goes a long way (I can cover my entire face and eyelids with less than one dropper) and it works better than anything else to make my skin more resilient to tolerate harsh actives and to recover quickly. Highly recommend!

B
Birgit
Excellent

Love the product

C
Carla

Now that I have the hang of applying this serum I just love it. Skin feel is instantly firm! Have only been using for about three weeks, but I can’t wait to see more changes with longer use!

C
Carla
Not impressed

There is so little of this product than I decided to use it every other day and only in the morning. It doesn’t leave my skin feeling any particular way. I think it must be doing something but it is hard to say with the amount provided. I will not buy again.

C
Catherine
Loshen you are the best!

I’ve been a loyal customer of Loshen & Crem for a while now, and they never cease to impress me with their curated selection of top-tier skincare products. I was thrilled to discover that they now carry Calecim, a brand I've heard so much about.

As always, the shopping experience at Loshen & Crem was seamless. Their customer service is exceptional—they truly go above and beyond to make sure you’re satisfied. The team is knowledgeable and always ready to offer personalized advice, which is so rare to find these days.

Adding Calecim to their lineup just reaffirms that Loshen & Crem is committed to offering the best in skincare. I can’t wait to see the results from using Calecim, and I’m so glad I can get it from a store I trust.

B
B.M.
Great Serum

Love this serum, so glad it's being sold here! It's pricey, but I feel it has helped keep my skin smooth and free from wrinkles.

S
Sarah
Hands down to the best serum

Nothing beats this serum. So happy Loshen carries the line

T
T.
Unreal

I use this SPARINGLY under my eyes and other delicate areas that need some extra care.

Worth the wait.

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