Microneedling
A device with fine needles creates controlled, tiny punctures in the skin. This stimulates the skin’s natural repair response and collagen production, helping improve the appearance of texture and fine lines over time.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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AnteAGE · Advanced skin care in Edmonton
A professional skin-support formula applied after microneedling, for skin that looks smoother, feels more hydrated and appears more even.
From $649 CAD · At our Edmonton facial studio
Let’s make it simple
At Loshen & Crem, P.E.A.R.L. is used exclusively after microneedling. Understanding the role of each makes the whole treatment easier to understand.
A device with fine needles creates controlled, tiny punctures in the skin. This stimulates the skin’s natural repair response and collagen production, helping improve the appearance of texture and fine lines over time.
Your facialist applies AnteAGE’s professional formula to the skin after microneedling. It brings together Biosomes, PDRN and other skin-conditioning ingredients to support visible skin quality.
P.E.A.R.L. is the topical formula in this appointment. Microneedling is the procedure; the formula is applied afterwards.
Begin with what you notice
Your goals guide the conversation. Together, we’ll consider whether this approach belongs in your skin-care plan.
You notice uneven texture or fine lines and want to explore a treatment that works gradually.
Your complexion looks tired or uneven, and you’re looking for a more refreshed appearance.
Your skin looks depleted, and hydration and skin quality are priorities you’d like to discuss.
Your skin’s condition matters as much as your goal. Sensitivity, active breakouts and irritation should be assessed before booking a procedure.
The science, translated
Five ingredient groups, each with a role. Select a letter to understand the formula without getting lost in the terminology.
The Biosome formula uses engineered, lipid-based particles designed to support advanced skin care.
Purified fragments of salmon-derived DNA, included to support hydration and the appearance of elasticity.
Tiny, lipid-based particles made without human-derived material, included as part of AnteAGE’s professional skin-support formula.
Ingredients that help defend against environmental stress and support a more even-looking complexion. They do not replace sunscreen.
Laboratory-produced signalling proteins selected to support the appearance of firmer, brighter skin.
Building blocks used in the formula to support hydration and skin-barrier care.
Your appointment, explained
We’ll explain your treatment plan and aftercare before you begin, with space for every question.
Discuss your goals, routine, allergies, recent treatments and health history. Your facialist assesses whether the service is appropriate.
Your facialist explains the procedure and comfort measures. Sensation varies with the area and treatment settings.
The professional formula is applied after microneedling as part of your appointment.
Leave knowing what to use, what to pause and when to resume your routine. Follow your facialist’s individual instructions.
Allow time for recovery. Temporary redness or darkening, warmth, swelling and sensitivity can follow microneedling. These reactions commonly settle within a few days to a week, depending on the treatment and your skin. Plan ahead for events. Learn about microneedling recovery.
Before
After
A closer look at the results
AnteAGE reports the following participant feedback after two P.E.A.R.L. Fusion services over eight weeks:
Brand-reported, self-assessed outcomes from an internal evaluation, August 2025. The public summary does not specify sample size or formulation. These findings concern the combined protocol and do not establish the formula’s effect on its own or guarantee results with our Biosome service. Read AnteAGE’s summary.
Before you book
You don’t need to arrive knowing the science. That’s what we’re here to help with.
At Loshen, P.E.A.R.L. is a topical formula applied after microneedling. The appointment involves a needling procedure, and the P.E.A.R.L. formula is applied to the surface afterwards.
Microneedling is the procedure. The P.E.A.R.L. appointment adds AnteAGE’s multi-ingredient formula afterwards. Ask your facialist how it compares with our other microneedling options for your skin and budget.
At Loshen, we use it exclusively after microneedling. If you’d prefer a facial without a needling procedure, our team can guide you to another service.
Suitability needs an individual assessment. Tell us about active irritation, skin infections, painful breakouts, healing concerns, medications and recent procedures. We may recommend waiting or choosing a different service.
AnteAGE describes the PDRN as salmon-derived. Tell our team about any fish allergy before booking so the formula and your suitability can be reviewed. A non-human-derived Biosome formula does not mean the full product is animal-free.
Changes from microneedling develop gradually over weeks, with fuller results potentially taking months. The number and spacing of visits depend on your skin, goals and response. We’ll discuss a plan rather than promise a set result.
Your aftercare instructions will cover makeup, cleansing, sun protection and when to restart active ingredients. Arrange your appointment when you can follow that plan. Contact us if recovery feels unexpected or symptoms worsen.
Our current P.E.A.R.L. service is listed from $649 CAD. The booking page shows the available appointment and current price. If you’re unsure whether to book the service or a consultation, contact us first.
Your skin, thoughtfully considered
Tell us what you’re noticing and what you’d like to change. We’ll help you understand your options and choose your next step with confidence.
At our facial studio
View current pricing and availability in our booking calendar.
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