Your routine
Jan MariniHyla3D® Face Cream Hyaluronic Acid Complex
Why it fits
A lightweight yet deeply hydrating face cream designed to replenish moisture, support the skin barrier, and restore a smoother, fuller-looking complexion.
Night Zyme™
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Explore La Crem rewardsAn overnight resurfacing complex designed to help transform dull, uneven skin while you sleep for a smoother, more polished, glass-like finish by morning.
Discover the formula & ingredientsPickup in Edmonton
Usually ready in 24 hours
Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Let’s talk about your skin and what belongs in your routine.
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Shipping, on usRegular $149+ · Priority $249+ CAD
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Selected with care.
Jan Marini
Night Zyme™
Your ritual begins with the right choice.
$173.00 CAD
Taxes calculated at checkout.
The skincare focus
Night Zyme™
An overnight resurfacing complex designed to help transform dull, uneven skin while you sleep for a smoother, more polished, glass-like finish by morning.
Explore our ingredient glossaryJan Marini
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Papaya Fruit Extract
A proteolytic enzyme that helps gently dissolve dead surface cells for smoother-looking skin.
Acetyl Tetrapeptide-2
Helps support skin renewal and improve the look of firmness and texture.
Acetyl Hexapeptide-8
Helps soften the appearance of expression lines for a smoother finish.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Explore another step in your face-care routine.
Your routine
Jan MariniC-ESTA® Cleansing Gel
Why it fits
A luxurious daily cleanser designed to cleanse while conditioning the skin with antioxidant support and a soft, refreshed finish. Enriched with vitamin C and DMAE, this lathering formula helps leave the skin feeling clean, smooth, and comfortably balanced while supporting a brighter, firmer-looking complexion. Suitable for all skin types, it brings a more treatment-focused feel to the cleansing step without compromising everyday ease.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
Night Zyme™
An overnight resurfacing complex designed to help transform dull, uneven skin while you sleep for a smoother, more polished, glass-like finish by morning. Powered by proteolytic enzyme technology, peptides, and deeply comforting hydrators, this overnight treatment helps digest dead surface cells without the feel of harsh exfoliation while supporting softer texture, improved skin quality, and a more refined-looking complexion. It is a beautiful final step for anyone wanting skin to look smoother, fresher, and more luminous with consistent nightly use.
Benefits
- Helps gently resurface the skin overnight
- Supports a smoother, more polished-looking complexion
- Helps improve the appearance of dullness and visible pores
- Encourages a more refined, glass-like skin finish
- Delivers hydration while supporting texture renewal
- Helps enhance overall skin quality and softness
- Suitable for combination, dry, and oily skin
How to use
- Apply as the final layer over all of your evening routine products
- Use nightly as directed
Full Ingredient List
Water/Aqua/Eau, Glycerin, Caprylic/Capric Triglyceride, Butyrospermum Parkii (Shea) Butter, Butylene Glycol, Polysilicone-11, Glyceryl Stearate, Cyclopentasiloxane, Cetyl Alcohol, Squalane, Carica Papaya (Papaya) Fruit Extract, Caryodendron Orinocense Seed Oil, Dimethicone, Palmitic Acid, Saccharide Isomerate, Stearic Acid, Echinacea Purpurea Extract, Glycine Soja (Soybean) Sterols, Persea Gratissima (Avocado) Oil, Polyglutamic Acid, Acetyl Tetrapeptide-2, Acetyl Hexapeptide-8, Mangifera Indica (Mango) Seed Butter, Panthenol, Olea Europaea (Olive) Leaf Extract, Hydrogenated Olive Oil Unsaponifiables, Tocopherol, Bisabolol, Sodium Stearoyl Glutamate, Laureth-12, Citric Acid, Sodium Citrate, Allantoin, Hydrolyzed Caesalpinia Spinosa Gum, Caesalpinia Spinosa Gum, Sodium Hydroxide, Carbomer, Myristic Acid, Potassium Sorbate, Sodium Benzoate, Caprylyl Glycol, Hexylene Glycol, Ethylhexylglycerin, Phenoxyethanol, CI 19140 (Yellow 5), CI 15985 (Yellow 6), CI 61570 (Green 5)
Shipping & returns
For delivery and return information, view our policy.
An overnight resurfacing complex designed to help transform dull, uneven skin while you sleep for a smoother, more polished, glass-like finish by morning. Powered by proteolytic enzyme technology, peptides, and deeply comforting hydrators, this overnight treatment helps digest dead surface cells without the feel of harsh exfoliation while supporting softer texture, improved skin quality, and a more refined-looking complexion. It is a beautiful final step for anyone wanting skin to look smoother, fresher, and more luminous with consistent nightly use.
Benefits:
- Helps gently resurface the skin overnight
- Supports a smoother, more polished-looking complexion
- Helps improve the appearance of dullness and visible pores
- Encourages a more refined, glass-like skin finish
- Delivers hydration while supporting texture renewal
- Helps enhance overall skin quality and softness
- Suitable for combination, dry, and oily skin
How to Use:
- Apply as the final layer over all of your evening routine products
- Use nightly as directed
Loshen & Crem’s Recommendation:
This is a beautiful option for anyone wanting a smoother, more polished complexion without relying on a stronger acid-based overnight treatment. It is especially lovely for skin that looks dull, textured, or less refined, and works beautifully as a finishing step when your goal is softer, more luminous skin by morning.
Ingredients:
Key Ingredients:
- Papaya Fruit Extract: A proteolytic enzyme that helps gently dissolve dead surface cells for smoother-looking skin.
- Acetyl Tetrapeptide-2: Helps support skin renewal and improve the look of firmness and texture.
- Acetyl Hexapeptide-8: Helps soften the appearance of expression lines for a smoother finish.
- Shea Butter: Helps nourish and support the skin barrier while adding comfort.
- Squalane: Helps moisturize and support skin softness without heaviness.
- Polyglutamic Acid: Helps attract and retain moisture for a plumper, more hydrated appearance.
- Panthenol: Helps support hydration and skin comfort.
- Bisabolol and Allantoin: Help calm and soothe the skin.
- Avocado Oil, Mango Seed Butter, Soybean Sterols, and Olive Unsaponifiables: Help replenish and soften the skin while supporting barrier function.
Full Ingredients List:
Water/Aqua/Eau, Glycerin, Caprylic/Capric Triglyceride, Butyrospermum Parkii (Shea) Butter, Butylene Glycol, Polysilicone-11, Glyceryl Stearate, Cyclopentasiloxane, Cetyl Alcohol, Squalane, Carica Papaya (Papaya) Fruit Extract, Caryodendron Orinocense Seed Oil, Dimethicone, Palmitic Acid, Saccharide Isomerate, Stearic Acid, Echinacea Purpurea Extract, Glycine Soja (Soybean) Sterols, Persea Gratissima (Avocado) Oil, Polyglutamic Acid, Acetyl Tetrapeptide-2, Acetyl Hexapeptide-8, Mangifera Indica (Mango) Seed Butter, Panthenol, Olea Europaea (Olive) Leaf Extract, Hydrogenated Olive Oil Unsaponifiables, Tocopherol, Bisabolol, Sodium Stearoyl Glutamate, Laureth-12, Citric Acid, Sodium Citrate, Allantoin, Hydrolyzed Caesalpinia Spinosa Gum, Caesalpinia Spinosa Gum, Sodium Hydroxide, Carbomer, Myristic Acid, Potassium Sorbate, Sodium Benzoate, Caprylyl Glycol, Hexylene Glycol, Ethylhexylglycerin, Phenoxyethanol, CI 19140 (Yellow 5), CI 15985 (Yellow 6), CI 61570 (Green 5)
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your order01 · Across Canada
A good thing, on its way.
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Papaya Fruit Extract
A proteolytic enzyme that helps gently dissolve dead surface cells for smoother-looking skin.
Acetyl Tetrapeptide-2
Helps support skin renewal and improve the look of firmness and texture.
Acetyl Hexapeptide-8
Helps soften the appearance of expression lines for a smoother finish.
Shea Butter
Helps nourish and support the skin barrier while adding comfort.
Squalane
Helps moisturize and support skin softness without heaviness.
Polyglutamic Acid
Helps attract and retain moisture for a plumper, more hydrated appearance.
Panthenol
Helps support hydration and skin comfort.
Bisabolol and Allantoin
Help calm and soothe the skin.
Avocado Oil, Mango Seed Butter, Soybean Sterols, and Olive Unsaponifiables
Help replenish and soften the skin while supporting barrier function.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore Jan Marini.
Find your place to begin.
Discover Night Zyme™ at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Jan Marini collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.