Your routine
Jan MariniHyla3D® Face Cream Hyaluronic Acid Complex
Why it fits
A lightweight yet deeply hydrating face cream designed to replenish moisture, support the skin barrier, and restore a smoother, fuller-looking complexion.
NeuroSmooth®
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Explore La Crem rewardsA cutting-edge topical treatment designed to help create a smoother, more refined, glass-like complexion by addressing visible pores, texture irregularity, and the look of skin fatigue.
Discover the formula & ingredientsPickup in Edmonton
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Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Shipping, on usRegular $149+ · Priority $249+ CAD
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Jan Marini
NeuroSmooth®
Your ritual begins with the right choice.
$287.00 CAD
Taxes calculated at checkout.
The skincare focus
NeuroSmooth®
A cutting-edge topical treatment designed to help create a smoother, more refined, glass-like complexion by addressing visible pores, texture irregularity, and the look of skin fatigue.
Explore our ingredient glossaryJan Marini
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Acetyl Hexapeptide-8
Helps support a smoother-looking complexion by targeting the appearance of expression-related texture.
Acetyl Tetrapeptide-2
Helps support skin firmness and a more toned appearance.
Tripeptide-56
Helps support collagen-related skin quality and smoothness.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Explore another step in your face-care routine.
Your routine
Jan MariniC-ESTA® Cleansing Gel
Why it fits
A luxurious daily cleanser designed to cleanse while conditioning the skin with antioxidant support and a soft, refreshed finish. Enriched with vitamin C and DMAE, this lathering formula helps leave the skin feeling clean, smooth, and comfortably balanced while supporting a brighter, firmer-looking complexion. Suitable for all skin types, it brings a more treatment-focused feel to the cleansing step without compromising everyday ease.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
NeuroSmooth®
A cutting-edge topical treatment designed to help create a smoother, more refined, glass-like complexion by addressing visible pores, texture irregularity, and the look of skin fatigue. Formulated with a multi-faceted blend of neuropeptides, collagen-supporting actives, soothing technologies, and recovery-focused ingredients, NeuroSmooth® helps soften the appearance of pores, improve tone uniformity, and support a more rested, luminous look. It is a beautiful standalone treatment and an ideal companion to injectable procedures.
Benefits
- Helps visibly soften the appearance of pores
- Refines the look of uneven texture
- Supports a smoother, more glass-like complexion
- Helps improve the look of skin tone uniformity
- Supports a more rested, youthful-looking appearance
- Helps calm visible redness and support recovery
- Ideal on its own or alongside injectable procedures
- Suitable for combination, dry, and oily skin
How to use
- Apply to clean skin as part of your daily routine
- Smooth evenly over the face
- Use morning and evening as directed
- Follow with the rest of your skincare routine
- Use sunscreen during the day
Full Ingredient List
Water/Aqua/Eau, Glycerin, Cyclopentasiloxane, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Propanediol, Phytonadione Epoxide, Butyrospermum Parkii (Shea) Butter, Cyclohexasiloxane, Dimethicone, Cetyl Alcohol, Octyldodecyl Stearoyl Stearate, Acetyl Hexapeptide-8, sh-Oligopeptide-4, Dipeptide-2, Palmitoyl Tetrapeptide-7, Acetyl Tetrapeptide-2, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Arnica Montana Flower Extract, Anigozanthos Flavidus Flower/Leaf Extract, Sodium Hyaluronate, Pentylene Glycol, Caprylyl Glycol, Cetearyl Alcohol, Cetearyl Glucoside, Glyceryl Stearate, Sorbitan Stearate, Sodium Stearoyl Glutamate, Glycine Soja (Soybean) Oil, Allantoin, Steareth-20, Hesperidin Methyl Chalcone, Citric Acid, Hydrogenated Phosphatidylcholine, Butylene Glycol, Disodium EDTA, Sodium Oleate, Xanthan Gum, Benzoic Acid, Sorbic Acid, Sodium Citrate, Sodium Benzoate, Potassium Sorbate, Benzyl Alcohol, Chlorhexidine Digluconate, Phenoxyethanol
Shipping & returns
For delivery and return information, view our policy.
A cutting-edge topical treatment designed to help create a smoother, more refined, glass-like complexion by addressing visible pores, texture irregularity, and the look of skin fatigue. Formulated with a multi-faceted blend of neuropeptides, collagen-supporting actives, soothing technologies, and recovery-focused ingredients, NeuroSmooth® helps soften the appearance of pores, improve tone uniformity, and support a more rested, luminous look. It is a beautiful standalone treatment and an ideal companion to injectable procedures.
Benefits:
- Helps visibly soften the appearance of pores
- Refines the look of uneven texture
- Supports a smoother, more glass-like complexion
- Helps improve the look of skin tone uniformity
- Supports a more rested, youthful-looking appearance
- Helps calm visible redness and support recovery
- Ideal on its own or alongside injectable procedures
- Suitable for combination, dry, and oily skin
How to Use:
- Apply to clean skin as part of your daily routine
- Smooth evenly over the face
- Use morning and evening as directed
- Follow with the rest of your skincare routine
- Use sunscreen during the day
Loshen & Crem’s Recommendation:
This is a beautiful option for anyone focused on smoother texture, softer-looking pores, and a more polished, reflective complexion. It is especially lovely for skin that feels less refined, more reactive, or in need of additional support after injectable treatments, offering benefits that help elevate overall skin quality and finish.
Ingredients:
Key Ingredients:
- Acetyl Hexapeptide-8: Helps support a smoother-looking complexion by targeting the appearance of expression-related texture.
- Acetyl Tetrapeptide-2: Helps support skin firmness and a more toned appearance.
- Tripeptide-56: Helps support collagen-related skin quality and smoothness.
- sh-Oligopeptide-4 (Thymosin Beta-4): Helps support visible skin recovery and repair.
- Palmitoyl Tetrapeptide-7: Helps calm the look of redness and support smoother-looking skin.
- Dipeptide-2: Helps support a more refreshed appearance, especially in skin that looks tired or puffy.
- Kangaroo Paw Extract: Helps support firmer, more resilient-looking skin.
- Hesperidin Methyl Chalcone: Helps support skin tone uniformity and visible post-procedure recovery.
- Vitamin K1 Oxide: Helps support the look of redness and post-procedure discoloration.
- Arnica Montana Flower Extract: Helps comfort the skin and support visible recovery.
Full Ingredients List:
Water/Aqua/Eau, Glycerin, Cyclopentasiloxane, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Propanediol, Phytonadione Epoxide, Butyrospermum Parkii (Shea) Butter, Cyclohexasiloxane, Dimethicone, Cetyl Alcohol, Octyldodecyl Stearoyl Stearate, Acetyl Hexapeptide-8, sh-Oligopeptide-4, Dipeptide-2, Palmitoyl Tetrapeptide-7, Acetyl Tetrapeptide-2, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Arnica Montana Flower Extract, Anigozanthos Flavidus Flower/Leaf Extract, Sodium Hyaluronate, Pentylene Glycol, Caprylyl Glycol, Cetearyl Alcohol, Cetearyl Glucoside, Glyceryl Stearate, Sorbitan Stearate, Sodium Stearoyl Glutamate, Glycine Soja (Soybean) Oil, Allantoin, Steareth-20, Hesperidin Methyl Chalcone, Citric Acid, Hydrogenated Phosphatidylcholine, Butylene Glycol, Disodium EDTA, Sodium Oleate, Xanthan Gum, Benzoic Acid, Sorbic Acid, Sodium Citrate, Sodium Benzoate, Potassium Sorbate, Benzyl Alcohol, Chlorhexidine Digluconate, Phenoxyethanol
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your order01 · Across Canada
A good thing, on its way.
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Acetyl Hexapeptide-8
Helps support a smoother-looking complexion by targeting the appearance of expression-related texture.
Acetyl Tetrapeptide-2
Helps support skin firmness and a more toned appearance.
Tripeptide-56
Helps support collagen-related skin quality and smoothness.
sh-Oligopeptide-4 (Thymosin Beta-4)
Helps support visible skin recovery and repair.
Palmitoyl Tetrapeptide-7
Helps calm the look of redness and support smoother-looking skin.
Dipeptide-2
Helps support a more refreshed appearance, especially in skin that looks tired or puffy.
Kangaroo Paw Extract
Helps support firmer, more resilient-looking skin.
Hesperidin Methyl Chalcone
Helps support skin tone uniformity and visible post-procedure recovery.
Vitamin K1 Oxide
Helps support the look of redness and post-procedure discoloration.
Arnica Montana Flower Extract
Helps comfort the skin and support visible recovery.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore Jan Marini.
Find your place to begin.
Discover NeuroSmooth® at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Jan Marini collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.