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Deviant SkincarePro-Biome Hydrating Cleanser
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A luxurious gel-cream cleanser designed to respect the skin barrier while supporting a balanced microbiome.
Deviant Skincare Peptide + GF Advanced Restore Cream
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Explore La Crem rewardsA next-generation skin longevity moisturizer powered by bioengineered growth factors, signalling peptides and biomimetic lipids to visibly firm, replenish and strengthen the skin.
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Deviant Skincare
Peptide + GF Advanced Restore Cream
Your ritual begins with the right choice.
$139.00 CAD
Taxes calculated at checkout.
The skincare focus
Deviant Skincare Peptide + GF Advanced Restore Cream
A next-generation skin longevity moisturizer powered by bioengineered growth factors, signalling peptides and biomimetic lipids to visibly firm, replenish and strengthen the skin.
Explore our ingredient glossaryDeviant Skincare
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Hyaluronic acid
A moisture-binding ingredient that helps skin feel hydrated and look smoother.
Ceramides
Skin-conditioning lipids that help support the moisture barrier.
Shea butter
A rich plant-derived emollient that helps soften and condition the skin.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Explore another step in your face-care routine.
Your routine
Deviant SkincareEssential Hydration Serum
Why it fits
A unique milky emulsion designed to deeply hydrate, fortify, and support the skin barrier for lasting comfort and resilience.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
Deviant Skincare Peptide + GF Advanced Restore Cream
Peptide + GF Advanced Restore Cream
A next-generation skin longevity moisturizer powered by bioengineered growth factors, signalling peptides and biomimetic lipids to visibly firm, replenish and strengthen the skin.
Designed for skin that needs more than moisture alone, Peptide + GF Advanced Restore Cream supports the essential systems responsible for firmness, elasticity, hydration and recovery.
A seven-part network of growth factors and signalling peptides helps reinforce the skin’s collagen- and elastin-rich structural network, while 19 biomimetic ceramides, lipids and amino acids replenish the moisture barrier. Five bioadaptive technologies further support skin exposed to environmental stress, sensitivity or intensive active skincare.
Rich yet beautifully wearable, it leaves the complexion looking fuller, smoother and more resilient—with the cushioning comfort of a moisturizer and the corrective intelligence of a treatment.
Benefits
- Visibly improves firmness, density and elasticity
- Softens the appearance of fine lines and expression wrinkles
- Replenishes essential lipids to strengthen the moisture barrier
- Delivers immediate and lasting hydration
- Helps skin appear plumper, smoother and more rested
- Calms the look of redness, sensitivity and irritation
- Supports recovery from environmental stress and intensive skincare routines
- Helps restore radiance to dull or fatigued-looking skin
- Creates a smooth, hydrated base beneath sunscreen and makeup
How to use
- After cleansing and applying your treatment serums, massage one to three pumps over the face, neck and décolleté using gentle upward motions.
- Use morning and evening. During the day, always complete your routine with broad-spectrum sunscreen.
Full Ingredient List
Aqua (Water), Glycerin, Caprylic/Capric Triglyceride, Simmondsia Chinensis (Jojoba) Seed Oil, Bifida Ferment Lysate, Dimethicone, Linoleic Acid, Cetearyl Alcohol, Butyrospermum Parkii (Shea) Butter, Ethylhexyl Palmitate, Panthenyl Triacetate, Rosa Canina (Rosehip) Fruit Oil, Bentonite, Betaine, Acetyl Glutamine, Ectoin, Ceramide NP, Ceramide AP, Inulin, Linolenic Acid, Cholesterol, Sodium PCA, Phytosphingosine, PCA, Palmitoyl Pentapeptide-4, Proline, Palmitoyl Tripeptide-1, sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-11, sh-Polypeptide-9, Palmitoyl Tetrapeptide-7, Sodium Hyaluronate, Ceramide EOP, Bacillus/Folic Acid Ferment Filtrate Extract, Lecithin, Jojoba Esters, Serine, Alanine, Glycine, Polyglycerin-3, Coco-Glucoside, Sodium Benzoate, Glutamic Acid, Lysine HCl, Threonine, Arginine, Glyceryl Stearate, Stearyl Alcohol, Cetyl Alcohol, Butylene Glycol, Sodium Lauroyl Lactylate, Sodium Stearoyl Glutamate, Helianthus Annuus (Sunflower) Seed Wax, Xanthan Gum, Naringenin, Sodium Lactate, Ethylhexylglycerin, Phenoxyethanol, Trihydroxystearin, 1,2-Hexanediol, Caprylyl Glycol, Carbomer, Tocopherol, Glucomannan, Citric Acid.
Shipping & returns
For delivery and return information, view our policy.
Peptide + GF Advanced Restore Cream
A next-generation skin longevity moisturizer powered by bioengineered growth factors, signalling peptides and biomimetic lipids to visibly firm, replenish and strengthen the skin.
Designed for skin that needs more than moisture alone, Peptide + GF Advanced Restore Cream supports the essential systems responsible for firmness, elasticity, hydration and recovery.
A seven-part network of growth factors and signalling peptides helps reinforce the skin’s collagen- and elastin-rich structural network, while 19 biomimetic ceramides, lipids and amino acids replenish the moisture barrier. Five bioadaptive technologies further support skin exposed to environmental stress, sensitivity or intensive active skincare.
Rich yet beautifully wearable, it leaves the complexion looking fuller, smoother and more resilient—with the cushioning comfort of a moisturizer and the corrective intelligence of a treatment.
Benefits
- Visibly improves firmness, density and elasticity
- Softens the appearance of fine lines and expression wrinkles
- Replenishes essential lipids to strengthen the moisture barrier
- Delivers immediate and lasting hydration
- Helps skin appear plumper, smoother and more rested
- Calms the look of redness, sensitivity and irritation
- Supports recovery from environmental stress and intensive skincare routines
- Helps restore radiance to dull or fatigued-looking skin
- Creates a smooth, hydrated base beneath sunscreen and makeup
Best For
- Loss of firmness, density or elasticity
- Fine lines and visible changes in skin texture
- Dry, dehydrated or moisture-depleted skin
- A weakened or compromised moisture barrier
- Sensitive, reactive or redness-prone skin
- Skin using retinoids or exfoliating acids
- Post-procedure routines, once approved by your skincare professional
- Dull, tired-looking skin lacking bounce and vitality
Why It Is Different
Rather than focusing on a single sign of ageing, Advanced Restore Cream takes a multi-pathway approach to skin longevity.
Its formula combines the skin’s scaffolding, structure and recovery systems in one daily moisturizer:
- Five bioengineered growth factors and two signalling peptides support the communication pathways associated with firmness, elasticity and renewal.
- Nineteen biomimetic ceramides, lipids and amino acids replenish components naturally found within the skin’s barrier and Natural Moisturizing Factor.
- Five bioadaptive technologies help skin remain hydrated, calm and resilient when challenged by environmental or cellular stress.
Understanding the Growth Factor Complex
-
Epidermal Growth Factor—EGF
Supports pathways associated with epidermal renewal and the maintenance of smoother, more refined-looking skin. -
Insulin-Like Growth Factor—IGF-1
Supports processes associated with cellular renewal and the maintenance of collagen and elastin. -
Vascular Endothelial Growth Factor—VEGF
Supports pathways associated with microcirculation, cellular nourishment and overall skin vitality. -
Acidic Fibroblast Growth Factor—FGF-1
Supports the structural pathways associated with firmness, elasticity and skin recovery. -
Basic Fibroblast Growth Factor—FGF-2
Supports fibroblast activity and the maintenance of collagen, elastin and hyaluronic acid within the skin.
The growth factors used in this formula are bioengineered and non-animal-derived. They are created through biotechnology to mimic signalling molecules naturally present within the skin while providing a controlled and consistent source within the formula.
How to Use
After cleansing and applying your treatment serums, massage one to three pumps over the face, neck and décolleté using gentle upward motions.
Use morning and evening. During the day, always complete your routine with broad-spectrum sunscreen.
Loshen’s Recommendation
This is the moisturizer we recommend when hydration alone is no longer enough—particularly when the skin feels depleted, less resilient or increasingly reactive while using retinoids, exfoliating acids or other corrective formulas.
For a comprehensive evening routine, pair Advanced Restore Cream with Retinal Clarity Serum. Apply the serum first to support renewal and address uneven texture, followed by the cream to replenish the moisture barrier and support firmness, comfort and recovery.
After a professional procedure, follow the timeline recommended by your facialist, dermatologist or treatment provider before reintroducing active skincare.
Ingredients
- Growth Factors and Signalling Peptides: A sophisticated network of bioengineered growth factors and biomimetic peptides that acts as cellular messengers. Together, they support the skin’s collagen- and elastin-rich structural network to improve the appearance of firmness, density and elasticity over time.
- Lipid Restore Complex: Skin-identical ceramides, cholesterol, fatty acids and phytosphingosine help replenish the structural lipids that form the moisture barrier. This supports barrier integrity, reduces moisture loss and restores comfort, softness and bounce.
- Biomimetic Hydra Matrix: A blend of amino acids and Natural Moisturizing Factors helps replenish the skin’s intrinsic hydration system. It supports the skin’s ability to attract, retain and regulate water for hydration that extends beyond the surface.
- 3D Filling Spheres: Moisture-binding microspheres expand within the skin’s upper layers to create an immediate micro-filling effect, visibly smoothing and plumping fine lines. Advanced hyaluronan technology provides additional hydration and longer-term firming support.
- Ectoin: A protective molecule that creates a lightweight hydration shield around the skin, helping defend it against pollution, temperature changes and other environmental stressors.
- Panthenyl Triacetate and Naringenin : A calming complex that helps soothe visible redness and irritation while supporting a more comfortable, balanced-looking complexion.
- Prebiotic and Postbiotic Recovery Complex: Helps maintain a balanced skin microbiome and supports recovery following disruption. By nourishing beneficial microorganisms, it promotes a calmer and more resilient skin environment.
Ingredients:
Aqua (Water), Glycerin, Caprylic/Capric Triglyceride, Simmondsia Chinensis (Jojoba) Seed Oil, Bifida Ferment Lysate, Dimethicone, Linoleic Acid, Cetearyl Alcohol, Butyrospermum Parkii (Shea) Butter, Ethylhexyl Palmitate, Panthenyl Triacetate, Rosa Canina (Rosehip) Fruit Oil, Bentonite, Betaine, Acetyl Glutamine, Ectoin, Ceramide NP, Ceramide AP, Inulin, Linolenic Acid, Cholesterol, Sodium PCA, Phytosphingosine, PCA, Palmitoyl Pentapeptide-4, Proline, Palmitoyl Tripeptide-1, sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-11, sh-Polypeptide-9, Palmitoyl Tetrapeptide-7, Sodium Hyaluronate, Ceramide EOP, Bacillus/Folic Acid Ferment Filtrate Extract, Lecithin, Jojoba Esters, Serine, Alanine, Glycine, Polyglycerin-3, Coco-Glucoside, Sodium Benzoate, Glutamic Acid, Lysine HCl, Threonine, Arginine, Glyceryl Stearate, Stearyl Alcohol, Cetyl Alcohol, Butylene Glycol, Sodium Lauroyl Lactylate, Sodium Stearoyl Glutamate, Helianthus Annuus (Sunflower) Seed Wax, Xanthan Gum, Naringenin, Sodium Lactate, Ethylhexylglycerin, Phenoxyethanol, Trihydroxystearin, 1,2-Hexanediol, Caprylyl Glycol, Carbomer, Tocopherol, Glucomannan, Citric Acid.
Please consult the product packaging for the most current ingredient list. If you have allergies or ingredient sensitivities, contact us at info@loshen.ca before purchasing.
Is This a Moisturizer or a Treatment?
It is both. Advanced Restore Cream provides the hydration, nourishment and barrier support expected from a moisturizer while incorporating advanced ingredients that address visible changes in firmness, elasticity, texture and resilience.
It can replace a traditional moisturizer rather than adding another step to your routine.
Can I Use It Morning and Night?
Yes. Apply it as your final moisturizing step morning and evening. Its cushioned texture layers comfortably beneath sunscreen and makeup during the day while providing replenishing support overnight.
Can I Use It With Retinoids and Exfoliating Acids?
Yes. The formula was designed to complement routines containing retinoids and exfoliating acids. Ceramides, biomimetic lipids, ectoin and soothing ingredients help maintain hydration and barrier comfort when the skin is placed under greater stress.
If your skin is highly reactive, introduce one new product at a time.
Is It Only for Mature Skin?
No. Skin longevity is about maintaining the skin’s firmness, hydration and resilience before advanced signs of ageing become visible.
Advanced Restore Cream is suitable for anyone noticing early changes in bounce, texture or barrier strength, as well as more established signs of ageing.
Is It Suitable for Sensitive Skin?
Yes. The fragrance-free and essential-oil-free formula was developed with sensitive, reactive and easily disrupted skin in mind.
If your skin is particularly reactive or allergy-prone, patch test before applying it to the entire face.
Can I Wear It Under Makeup?
Yes. Its plumping, cushioned texture absorbs to a smooth and comfortable finish, creating a hydrated base beneath sunscreen and makeup without leaving the skin feeling greasy.
Is It Vegan?
Yes. Advanced Restore Cream is vegan and formulated without animal-derived ingredients. Its growth factor complex is created using biotechnology.
Can It Be Used During Pregnancy or Breastfeeding?
The formula does not contain retinoids and is considered suitable for use during pregnancy and breastfeeding by the manufacturer. Because individual circumstances differ, we always recommend confirming new skincare products with your physician.
Where Can I Buy Peptide + GF Advanced Restore Cream in Canada?
Peptide + GF Advanced Restore Cream is available from Loshen & Crem online and at our Edmonton skincare boutique. We ship across Canada and to the United States.
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your order01 · Across Canada
A good thing, on its way.
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Hyaluronic acid
A moisture-binding ingredient that helps skin feel hydrated and look smoother.
Ceramides
Skin-conditioning lipids that help support the moisture barrier.
Shea butter
A rich plant-derived emollient that helps soften and condition the skin.
Jojoba
A botanical emollient that helps soften the skin and gives formulas a smooth feel.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore Deviant Skincare.
Find your place to begin.
Discover Deviant Skincare Peptide + GF Advanced Restore Cream at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Deviant Skincare collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.