Your routine
Skinbetter ScienceTrio Rebalancing Moisture Treatment
Why it fits
Trio Rebalancing Moisture Treatment completes the duo with a moisturizer for both morning and evening.

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Explore La Crem rewardsAnyone starting a considered routine
A two-step introduction to Skinbetter Science for anyone starting a more considered routine. Alto Advanced brings antioxidant care day and night, while AlphaRet Overnight Cream adds retinoid renewal in the evening.
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5238 Windermere Boulevard
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The skincare focus
A two-step introduction to Skinbetter Science for anyone starting a more considered routine. Alto Advanced brings antioxidant care day and night, while AlphaRet Overnight Cream adds retinoid renewal in the evening.
Explore our ingredient glossarySkinbetter Science
The ingredients behind this formula—and what they bring to your skin.
Pyrroloquinoline Quinone Allyl Ester (Allyl PQQ)
Skinbetter Science's patented antioxidant technology in Alto, aimed at free radicals generated within the skin.
Tetrahexyldecyl Ascorbate
An oil-soluble form of vitamin C that helps defend skin against free radicals.
Ethyl Lactyl Retinoate (AlphaRet)
The patented pairing of a retinoid and lactic acid in AlphaRet Overnight Cream.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Add a gentle cleanser, a moisturizer and a daily sunscreen for a full routine. Avoid other retinoids or strong exfoliants with AlphaRet.
Your routine
Trio Rebalancing Moisture Treatment completes the duo with a moisturizer for both morning and evening.
Your routine
A gentle daily cleanser and the first step of your routine, before serum and moisturizer.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Skinbetter Science A-Team Duo Set pairs two of the brand's signature formulas in travel-friendly 15 ml sizes. It covers the two foundations of a thoughtful routine: antioxidant care and retinoid renewal.
Alto Advanced Defense and Repair Serum combines vitamins C and E with Allyl PQQ and a botanical antioxidant blend to help skin look brighter and more even. Use it morning and evening.
AlphaRet Overnight Cream pairs a patented retinoid with lactic and glycolic acids, plus a moisturizing blend, to help skin look smoother at night. Together they make a simple day-to-night ritual.
Two products, two clear roles: protect by day, renew by night. That simplicity is what makes a routine stick. The smaller sizes let you discover how your skin responds before investing in full sizes. We like it as a first step into Skinbetter Science.
Anyone starting a considered routine
Let Alto settle for a minute before applying AlphaRet so each layer spreads evenly.
Alto Advanced Defense and Repair Serum:
Aqua/Water/Eau, Butylene Glycol, Propanediol, Ethylhexyl Olivate, Cetearyl Alcohol, Chlorogenic Acids, Niacinamide, Lauryl Lactate, Dimethyl Isosorbide, Pyrroloquinoline Quinone Allyl Ester, Hydrolyzed Sodium Hyaluronate, Glycyrrhiza Glabra Root Extract / Licorice Root Extract, Tetrahexyldecyl Ascorbate, Ergothioneine, Taraxacum Officinale Rhizome / Root Extract – Dandelion Rhizome/Root Extract, Arabidopsis Thaliana Extract, Carnosine, Camellia Sinensis Leaf Extract, Vitis Vinifera Seed Extract / Grape Seed Extract, Theobroma Cacao Seed Extract / Cocoa Seed Extract, Curcuma Longa Root Extract / Turmeric Root Extract, Olea Europaea Fruit Extract / Olive Fruit Extract, Euterpe Oleracea Fruit Extract, Palmitoyl Tripeptide-1, Buddleja Officinalis Flower Extract, Coffea Arabica Seed Extract / Coffee Seed Extract, Crocus Sativus Callus Extract, Superoxide Dismutase, Ubiquinone, Plankton Extract, Micrococcus Lysate, Arginine, Zingiber Officinale Root Extract / Ginger Root Extract, Ceramide NP, Ceramide AP, Ceramide EOP, Linoleic Acid, Linolenic Acid, Ascorbic Acid, Bisabolol, Tocopherol, Tocopheryl Acetate, Cholesterol, Phytosphingosine, Jojoba Esters, Sodium PCA, Methyl Gluceth-20, Glycerin, Helianthus Annuus Seed Cera / Sunflower Seed Wax, Acacia Decurrens Flower Cera / Acacia Decurrens Flower Wax, Lecithin, Sodium Lauroyl Lactylate, Dicetyl Phosphate, Propanediol Dicaprylate / Caprate, Polyglycerin-3, Ceteth-20 Phosphate, Diisostearyl Malate, Xanthan Gum, Steareth-2, Acacia Senegal Gum, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Maltodextrin, Ricinoleth-40, Sodium Hydroxide, Citric Acid, Sodium Phytate, Ethylhexylglycerin, Phenoxyethanol, Ethylhexyl Palmitate, Alcohol, Lactic Acid, Pentylene Glycol, Sorbitan Isostearate, Tribehenin
AlphaRet Overnight Cream:
Aqua/Water, Sodium Glycolate, Glycolic Acid, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide NP, Hyaluronic Acid, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii (Shea) Butter, Allantoin Glycyrrhetinic Acid, Sodium PCA, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Tromethamine, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, Titanium Dioxide (CI 77891).
Alto Advanced Defense and Repair Serum and AlphaRet Overnight Cream, each in a 15 ml size.
Apply Alto first, then AlphaRet, then moisturizer if needed.
Yes, with a gradual start. Use AlphaRet a few evenings a week and increase as your skin is comfortable.
Yes. Antioxidants do not replace sunscreen, and AlphaRet contains a retinoid and alpha hydroxy acids.
AlphaRet contains a topical retinoid. Speak with your physician before use if you are pregnant, breastfeeding or planning a pregnancy.
For delivery and return information, view our policy.
A two-step introduction to Skinbetter Science for anyone starting a more considered routine. Alto Advanced brings antioxidant care day and night, while AlphaRet Overnight Cream adds retinoid renewal in the evening.
Skinbetter Science A-Team Duo Set pairs two of the brand's signature formulas in travel-friendly 15 ml sizes. It covers the two foundations of a thoughtful routine: antioxidant care and retinoid renewal.
Alto Advanced Defense and Repair Serum combines vitamins C and E with Allyl PQQ and a botanical antioxidant blend to help skin look brighter and more even. Use it morning and evening.
AlphaRet Overnight Cream pairs a patented retinoid with lactic and glycolic acids, plus a moisturizing blend, to help skin look smoother at night. Together they make a simple day-to-night ritual.
Two products, two clear roles: protect by day, renew by night. That simplicity is what makes a routine stick. The smaller sizes let you discover how your skin responds before investing in full sizes. We like it as a first step into Skinbetter Science.
Alto Advanced Defense and Repair Serum
Aqua/Water/Eau, Butylene Glycol, Propanediol, Ethylhexyl Olivate, Cetearyl Alcohol, Chlorogenic Acids, Niacinamide, Lauryl Lactate, Dimethyl Isosorbide, Pyrroloquinoline Quinone Allyl Ester, Hydrolyzed Sodium Hyaluronate, Glycyrrhiza Glabra Root Extract / Licorice Root Extract, Tetrahexyldecyl Ascorbate, Ergothioneine, Taraxacum Officinale Rhizome / Root Extract – Dandelion Rhizome/Root Extract, Arabidopsis Thaliana Extract, Carnosine, Camellia Sinensis Leaf Extract, Vitis Vinifera Seed Extract / Grape Seed Extract, Theobroma Cacao Seed Extract / Cocoa Seed Extract, Curcuma Longa Root Extract / Turmeric Root Extract, Olea Europaea Fruit Extract / Olive Fruit Extract, Euterpe Oleracea Fruit Extract, Palmitoyl Tripeptide-1, Buddleja Officinalis Flower Extract, Coffea Arabica Seed Extract / Coffee Seed Extract, Crocus Sativus Callus Extract, Superoxide Dismutase, Ubiquinone, Plankton Extract, Micrococcus Lysate, Arginine, Zingiber Officinale Root Extract / Ginger Root Extract, Ceramide NP, Ceramide AP, Ceramide EOP, Linoleic Acid, Linolenic Acid, Ascorbic Acid, Bisabolol, Tocopherol, Tocopheryl Acetate, Cholesterol, Phytosphingosine, Jojoba Esters, Sodium PCA, Methyl Gluceth-20, Glycerin, Helianthus Annuus Seed Cera / Sunflower Seed Wax, Acacia Decurrens Flower Cera / Acacia Decurrens Flower Wax, Lecithin, Sodium Lauroyl Lactylate, Dicetyl Phosphate, Propanediol Dicaprylate / Caprate, Polyglycerin-3, Ceteth-20 Phosphate, Diisostearyl Malate, Xanthan Gum, Steareth-2, Acacia Senegal Gum, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Maltodextrin, Ricinoleth-40, Sodium Hydroxide, Citric Acid, Sodium Phytate, Ethylhexylglycerin, Phenoxyethanol, Ethylhexyl Palmitate, Alcohol, Lactic Acid, Pentylene Glycol, Sorbitan Isostearate, Tribehenin
AlphaRet Overnight Cream
Aqua/Water, Sodium Glycolate, Glycolic Acid, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide NP, Hyaluronic Acid, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii (Shea) Butter, Allantoin Glycyrrhetinic Acid, Sodium PCA, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Tromethamine, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, Titanium Dioxide (CI 77891).
Please refer to the packaging of your product for the most up-to-date ingredient list.
Sun sensitivity: This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing and limit sun exposure while using this product and for a week afterwards.
Pregnancy and breastfeeding: This product contains a topical retinoid. If you are pregnant, breastfeeding or planning a pregnancy, speak with your physician before use.
Caution: For external use only. Avoid contact with eyes; if contact occurs, rinse thoroughly with water. If irritation persists, discontinue use and consult a physician.
Explore Skinbetter Science at Loshen & Crem, our skin-health boutique and facial studio in Edmonton. We ship across Canada, and our team is happy to help you find the right routine.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Skinbetter Science's patented antioxidant technology in Alto, aimed at free radicals generated within the skin.
An oil-soluble form of vitamin C that helps defend skin against free radicals.
The patented pairing of a retinoid and lactic acid in AlphaRet Overnight Cream.
An alpha hydroxy acid in AlphaRet that helps refine the look of rough texture.
Vitamin B3, found in both formulas, which helps hydration and the look of an even tone.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Skinbetter Science A-Team Duo Set at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Skinbetter Science collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.