Your routine
Biologique RechercheLait VIP O₂
Why it fits
The cleansing step and the first step of your Biologique Recherche routine, removing makeup, sunscreen and impurities before your Lotion P50.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsDevitalized-looking skin
An intensive serum concentrate in single vials, over-boosted with 56 active ingredients, to visibly revitalize even the most devitalized-looking skin. One vial covers two applications.
Discover the formula & ingredientsPickup in Edmonton
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Biologique Recherche
Your ritual begins with the right choice.
$1,550.00 CAD
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The skincare focus
An intensive serum concentrate in single vials, over-boosted with 56 active ingredients, to visibly revitalize even the most devitalized-looking skin. One vial covers two applications.
Explore our ingredient glossaryBiologique Recherche
The ingredients behind this formula—and what they bring to your skin.
Oligopeptide-24, Acetyl Decapeptide-3, Decapeptide-4 & Tripeptide-6
Peptides included in the formula's smoothing and revitalizing complex.
Copper Tripeptide-1
A copper peptide that helps condition the skin.
Amino Acids
A blend of 24 amino acids, including Glycine, Proline, Serine and Arginine, that helps support skin hydration.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Cleanse with the milk selected for your Skin Instant, then apply the Lotion P50 selected for your Skin Instant before the vial. Continue with the cream chosen for your Skin Instant, and add a broad-spectrum sunscreen in the morning. The full protocol should be personalized by your esthetician.
Your routine
The cleansing step and the first step of your Biologique Recherche routine, removing makeup, sunscreen and impurities before your Lotion P50.
Your routine
Biologique Recherche’s exfoliating, purifying and balancing lotion for seborrheic Skin Instants. The first step after cleansing.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Biologique Recherche Cocktail d'Actifs Régénérants is an intensive concentrate designed to visibly revitalize the skin, one vial at a time. This serum is over-boosted with 56 active ingredients developed using cutting-edge biotechnology and vitamins, for a visible, multi-action result across six benefits, even on the most devitalized-looking skin.
Its formula brings together peptides, a copper peptide, a blend of 24 amino acids and a multivitamin complex including vitamin C, retinol, vitamin E, niacinamide and biotin, along with glutathione, coenzyme A and nicotinamide adenine dinucleotide. It helps reduce the appearance of fine lines and wrinkles, improves hydration and tone, and leaves the skin feeling smoother.
The kit contains 10 vials for a total of 20 applications: each vial is good for two applications, applied one day and then the next. Refrigerate after opening.
When skin looks tired, dull and devitalized, we like having a concentrate that does several things at once. Cocktail d'Actifs Régénérants packs peptides, amino acids, vitamins and antioxidants into one vial, so it covers fine lines, hydration, tone and texture in a single step. We also love the format: each vial is split over two days, which makes it easy to follow as a focused course. It is a beautiful way to give a tired-looking complexion a visible boost.
Devitalized-looking skin
Keep the opened vial in the fridge so the second half is ready for the next day's application.
WATER (AQUA), OLIGOPEPTIDE-24, TRIPEPTIDE-6, ACETYL DECAPEPTIDE-3, DECAPEPTIDE-4, GLUTAMINE, AMINOBUTYRIC ACID, ASCORBIC ACID, ALANINE, ARGININE, LYSINE, VALINE, HISTIDINE, LEUCINE, THREONINE, ISOLEUCINE, TRYPTOPHAN, PHENYLALANINE, TYROSINE, GLYCINE, SERINE, ADENOSINE CYCLIC PHOSPHATE, ASPARTIC ACID, COPPER TRIPEPTIDE-1, CYSTINE, CYTOSINE, GLUTATHIONE, GUANOSINE, NIACINAMIDE, THYMINE, ASPARAGINE, GLUTAMIC ACID, NICOTINAMIDE ADENINE DINUCLEOTIDE, ORNITHINE, PROLINE, HYDROXYPROLINE, METHIONINE, TAURINE, COENZYME A, DISODIUM FLAVINE ADENINE DINUCLEOTIDE, THIAMINE DIPHOSPHATE, CYANOCOBALAMIN, RETINOL, THIAMINE NITRATE, INOSITOL, BIOTIN, CALCIUM PANTOTHENATE, FOLIC ACID, MENADIONE, RIBOFLAVIN, CALCIUM CHLORIDE, TOCOPHEROL, SODIUM PHOSPHATE, MAGNESIUM SULFATE, PYRIDOXINE, POTASSIUM CHLORIDE.
The kit contains 10 vials for a total of 20 applications. Each vial is good for two applications.
After cleansing and Lotion P50, apply one half of the vial to the face, neck and décolleté, then repeat with the second half the following day.
Refrigerate after opening.
No. Avoid the eye contour area.
56 active ingredients, including peptides, a copper peptide, a blend of 24 amino acids, a multivitamin complex with retinol, and antioxidant ingredients such as vitamin C, vitamin E and glutathione.
It is designed for a visible, multi-action result, even on the most devitalized-looking skin. Our estheticians can confirm whether it suits your current Skin Instant.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
For delivery and return information, view our policy.
Biologique Recherche Cocktail d'Actifs Régénérants is an intensive concentrate designed to visibly revitalize the skin, one vial at a time. This serum is over-boosted with 56 active ingredients developed using cutting-edge biotechnology and vitamins, for a visible, multi-action result across six benefits, even on the most devitalized-looking skin.
Its formula brings together peptides, a copper peptide, a blend of 24 amino acids and a multivitamin complex including vitamin C, retinol, vitamin E, niacinamide and biotin, along with glutathione, coenzyme A and nicotinamide adenine dinucleotide. It helps reduce the appearance of fine lines and wrinkles, improves hydration and tone, and leaves the skin feeling smoother.
The kit contains 10 vials for a total of 20 applications: each vial is good for two applications, applied one day and then the next. Refrigerate after opening.
WATER (AQUA), OLIGOPEPTIDE-24, TRIPEPTIDE-6, ACETYL DECAPEPTIDE-3, DECAPEPTIDE-4, GLUTAMINE, AMINOBUTYRIC ACID, ASCORBIC ACID, ALANINE, ARGININE, LYSINE, VALINE, HISTIDINE, LEUCINE, THREONINE, ISOLEUCINE, TRYPTOPHAN, PHENYLALANINE, TYROSINE, GLYCINE, SERINE, ADENOSINE CYCLIC PHOSPHATE, ASPARTIC ACID, COPPER TRIPEPTIDE-1, CYSTINE, CYTOSINE, GLUTATHIONE, GUANOSINE, NIACINAMIDE, THYMINE, ASPARAGINE, GLUTAMIC ACID, NICOTINAMIDE ADENINE DINUCLEOTIDE, ORNITHINE, PROLINE, HYDROXYPROLINE, METHIONINE, TAURINE, COENZYME A, DISODIUM FLAVINE ADENINE DINUCLEOTIDE, THIAMINE DIPHOSPHATE, CYANOCOBALAMIN, RETINOL, THIAMINE NITRATE, INOSITOL, BIOTIN, CALCIUM PANTOTHENATE, FOLIC ACID, MENADIONE, RIBOFLAVIN, CALCIUM CHLORIDE, TOCOPHEROL, SODIUM PHOSPHATE, MAGNESIUM SULFATE, PYRIDOXINE, POTASSIUM CHLORIDE.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Peptides included in the formula's smoothing and revitalizing complex.
A copper peptide that helps condition the skin.
A blend of 24 amino acids, including Glycine, Proline, Serine and Arginine, that helps support skin hydration.
A multivitamin complex including Ascorbic Acid, Retinol, Tocopherol, Niacinamide and Biotin; Ascorbic Acid and Tocopherol provide antioxidant support.
Included in the formula's revitalizing complex; Glutathione is known for its antioxidant properties.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Biologique Recherche Cocktail d’Actifs Régénérants at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Biologique Recherche collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.