Your routine
GlyMed PlusComfort Cream with Aloe Vera
Why it fits
A light yet deeply nourishing moisturizer designed to hydrate, soothe, and protect compromised, reactive, or sensitized skin.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsRetinol Rejuvenation Serum is a potent anti-aging serum that targets multiple skin concerns to leave your complexion smoother, brighter, and more youthful.
Discover the formula & ingredientsPickup in Edmonton
Usually ready in 24 hours
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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GlyMed Plus
Your ritual begins with the right choice.
$156.50 CAD
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The skincare focus
Retinol Rejuvenation Serum is a potent anti-aging serum that targets multiple skin concerns to leave your complexion smoother, brighter, and more youthful.
Explore our ingredient glossaryGlyMed Plus
The ingredients behind this formula—and what they bring to your skin.
Retinol
A derivative of vitamin A that accelerates cell turnover, improves skin texture, and stimulates collagen production to reduce fine lines and wrinkles.
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
A peptide cocktail that stimulates collagen production, firms, and strengthens the skin.
Hyaluronic Acid
Provides intense hydration, plumping the skin and helping to retain moisture for a healthy, youthful complexion.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Explore another step in your face-care routine.
Your routine
A light yet deeply nourishing moisturizer designed to hydrate, soothe, and protect compromised, reactive, or sensitized skin.
Your routine
GlyMed Plus Mega Cream Cleanser is an ultra-gentle cream cleanser that effectively dissolves makeup and oil, providing a deep, yet soothing and hydrating cleanse. It is designed to be both thorough and gentle, ensuring that the skin is left clean, soft, and moisturized.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Retinol Rejuvenation Serum is a potent anti-aging serum that targets multiple skin concerns to leave your complexion smoother, brighter, and more youthful. Formulated with a maximum concentration of 5% retinol, this serum accelerates cell turnover, boosts collagen production, and enhances skin texture while minimizing fine lines, wrinkles, pigmentation, and breakouts. The advanced micro-encapsulation technology ensures that the retinol is released slowly into the skin, reducing irritation for even sensitive skin. Infused with peptides and hyaluronic acid, it provides essential hydration, strengthening the skin and improving its overall appearance.
Ingredients (INCI): Aqua (Water), Cetearyl Ethylhexanoate, Caprylic/Capric Triglyceride, Hyaluronic Acid, Retinol (Vitamin A), Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate, Olea Europaea (Olive) Oil, Limnanthes Alba (Meadowfoam) Seed Oil, Tocopheryl Acetate (Vitamin E Acetate), Retinyl Palmitate (Vitamin A Ester), Glycerin, Sucrose Tristearate, Bis-Diglyceryl Polyacyladipate-2, Polysorbate 60, PEG-20, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Butylene Glycol, Rosmarinus Officinalis (Rosemary) Leaf Oil, Pelargonium Graveolens (Geranium) Oil, Phenoxyethanol, Ethylhexylglycerin, Triethanolamine.
For delivery and return information, view our policy.
Retinol Rejuvenation Serum is a potent anti-aging serum that targets multiple skin concerns to leave your complexion smoother, brighter, and more youthful. Formulated with a maximum concentration of 5% retinol, this serum accelerates cell turnover, boosts collagen production, and enhances skin texture while minimizing fine lines, wrinkles, pigmentation, and breakouts. The advanced micro-encapsulation technology ensures that the retinol is released slowly into the skin, reducing irritation for even sensitive skin. Infused with peptides and hyaluronic acid, it provides essential hydration, strengthening the skin and improving its overall appearance.
Ingredients (INCI): Aqua (Water), Cetearyl Ethylhexanoate, Caprylic/Capric Triglyceride, Hyaluronic Acid, Retinol (Vitamin A), Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate, Olea Europaea (Olive) Oil, Limnanthes Alba (Meadowfoam) Seed Oil, Tocopheryl Acetate (Vitamin E Acetate), Retinyl Palmitate (Vitamin A Ester), Glycerin, Sucrose Tristearate, Bis-Diglyceryl Polyacyladipate-2, Polysorbate 60, PEG-20, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Butylene Glycol, Rosmarinus Officinalis (Rosemary) Leaf Oil, Pelargonium Graveolens (Geranium) Oil, Phenoxyethanol, Ethylhexylglycerin, Triethanolamine.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
A derivative of vitamin A that accelerates cell turnover, improves skin texture, and stimulates collagen production to reduce fine lines and wrinkles.
A peptide cocktail that stimulates collagen production, firms, and strengthens the skin.
Provides intense hydration, plumping the skin and helping to retain moisture for a healthy, youthful complexion.
A stable form of vitamin A that delivers antioxidant protection and reduces dryness and flakiness in the skin.
An antioxidant that soothes the skin, brightens complexion, and protects against environmental damage.
Curious about your ingredients?
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Expert guidance. A considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover GlyMed Retinol Rejuvenation Serum at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the GlyMed Plus collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
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