Your routine
mesoesteticHydracream Fusion
Why it fits
Balancing, anti-pollution cleansing facial cream-oil. It provides nourishment and hydration to the skin, leaving it beautifully smooth.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsFor experienced skincare users. One of the most potent dark-spot treatments available for home use. Please speak with our team before starting.
Discover the formula & ingredientsPickup in Edmonton
Usually ready in 24 hours
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Selected with care.
mesoestetic
Your ritual begins with the right choice.
$518.00 CAD
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The skincare focus
For experienced skincare users. One of the most potent dark-spot treatments available for home use. Please speak with our team before starting.
Explore our ingredient glossarymesoestetic
The ingredients behind this formula—and what they bring to your skin.
Niacinamide
A form of vitamin B3 used in skin care to support the moisture barrier and a more even-looking complexion.
Glycerin
A humectant that helps attract moisture and keep skin feeling hydrated.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Explore another step in your face-care routine.
Your routine
Balancing, anti-pollution cleansing facial cream-oil. It provides nourishment and hydration to the skin, leaving it beautifully smooth.
Your routine
Intensive concentrate with a calming effect and high skin tolerance. It soothes sensitive and sensitized skin and visibly reduces localized redness and the look of irritation. With antioxidant and rebalancing ingredients for balanced, resilient-looking skin.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
For experienced skincare users. One of the most potent dark-spot treatments available for home use. Please speak with our team before starting.
dermamelan treatment is a home cream that visibly reduces and helps control the look of dark spots on the face. It is designed to complete the dark-spot correcting action of the dermamelan method. Continuous use visibly reduces dark spots and helps prevent their reappearance.
Call us on 780-722-9086 or email us at info@loshen.ca. Our Skin Experts will guide you to the perfect selection of this advanced cosmeceutical product.
Aqua, Glyceryl Stearate, Glycofurol, Silica, PEG-75 Stearate, PEG-8, Polyamide-5, Kojic Dipalmitate, Glycereth-26, Niacinamide, Ethoxydiglycol, C12-15 Alkyl Benzoate, Octyldodecanol, PPG-15 Stearyl Ether, 4-Butyresorcinol, Coco-Caprylate/Caprate, Glyceryl Behenate, Poloxamer 338, Glycyrrhiza Glabra Root Extract, Dihydroxychalcone Sulfonic Acid, Piper Nigrum Fruit Extract, Retinol, Hydroxydecyl Ubiquinone, Magnesium Ascorbyl Phosphate, Retinyl Palmitate, Diosmine, Ferulic Acid, Tocopheryl Acetate, Silica Dimethyl Silylate, Coconut Alkanes, PPG-12/SMDI Copolymer, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Mannitol, Phosphatidylcholine, Glycerin, Cholesterol, Sodium Hydroxide, Polysorbate 80, Xanthan Gum, BHT, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol, Sodium Metabisulfite, Methylparaben, Propylparaben, Ethylparaben, Parfum, Caramel.
Mesoestetic products are designed to deliver real, visible results on dark spots and uneven tone. These are powerful, professional-grade treatments—not your everyday skincare—and they require a tailored approach to ensure safety and effectiveness. While we respect recommendations from other professionals, please note that if you purchase Mesoestetic from Loshen & Crem without a direct recommendation from our own team, we cannot accept returns, refunds, or credits in the event of sensitivity or an allergic reaction. Our professionals take great care to assess each client’s skin needs, knowing that these active ingredients, though transformative, may not be suitable for everyone. As an authorized retailer, Loshen & Crem provides only the latest formulations to ensure you’re getting the best results possible. Thank you for trusting Loshen & Crem with your skincare journey. We’re here to support you with expertise, care, and a commitment to helping you achieve safe, beautiful results.
For delivery and return information, view our policy.
For experienced skincare users. One of the most potent dark-spot treatments available for home use. Please speak with our team before starting.
dermamelan treatment is a home cream that visibly reduces and helps control the look of dark spots on the face. It is designed to complete the dark-spot correcting action of the dermamelan method. Continuous use visibly reduces dark spots and helps prevent their reappearance.
Call us on 780-722-9086 or email us at info@loshen.ca. Our Skin Experts will guide you to the perfect selection of this advanced cosmeceutical product.
Precautions for use
Wash hands after application to avoid direct contact with eyes and mucous membranes, if necessary, rinse with plenty of water. Keep out of the reach of children.
Aqua, Glyceryl Stearate, Glycofurol, Silica, PEG-75 Stearate, PEG-8, Polyamide-5, Kojic Dipalmitate, Glycereth-26, Niacinamide, Ethoxydiglycol, C12-15 Alkyl Benzoate, Octyldodecanol, PPG-15 Stearyl Ether, 4-Butyresorcinol, Coco-Caprylate/Caprate, Glyceryl Behenate, Poloxamer 338, Glycyrrhiza Glabra Root Extract, Dihydroxychalcone Sulfonic Acid, Piper Nigrum Fruit Extract, Retinol, Hydroxydecyl Ubiquinone, Magnesium Ascorbyl Phosphate, Retinyl Palmitate, Diosmine, Ferulic Acid, Tocopheryl Acetate, Silica Dimethyl Silylate, Coconut Alkanes, PPG-12/SMDI Copolymer, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Mannitol, Phosphatidylcholine, Glycerin, Cholesterol, Sodium Hydroxide, Polysorbate 80, Xanthan Gum, BHT, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol, Sodium Metabisulfite, Methylparaben, Propylparaben, Ethylparaben, Parfum, Caramel.
Mesoestetic products are designed to deliver real, visible results on dark spots and uneven tone. These are powerful, professional-grade treatments—not your everyday skincare—and they require a tailored approach to ensure safety and effectiveness.
While we respect recommendations from other professionals, please note that if you purchase Mesoestetic from Loshen & Crem without a direct recommendation from our own team, we cannot accept returns, refunds, or credits in the event of sensitivity or an allergic reaction. Our professionals take great care to assess each client’s skin needs, knowing that these active ingredients, though transformative, may not be suitable for everyone.
As an authorized retailer, Loshen & Crem provides only the latest formulations to ensure you’re getting the best results possible.
Thank you for trusting Loshen & Crem with your skincare journey. We’re here to support you with expertise, care, and a commitment to helping you achieve safe, beautiful results.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
A form of vitamin B3 used in skin care to support the moisture barrier and a more even-looking complexion.
A humectant that helps attract moisture and keep skin feeling hydrated.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Dermamelan® Treatment at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the mesoestetic collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
Curious about…
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