
Biologique Recherche Lotion MC110
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An intensive exfoliating, renewing and plumping lotion used as a 10-day course. Recommended by Biologique Recherche for thin-to-normal Skin Instants with fine lines, uneven-looking texture or reduced radiance.
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Regular $149+
Priority $249+
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Prioritaire dès 249 $
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Biologique Recherche Lotion MC110
30 ml
Loshen & Crem
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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At a glance
- Step
- Intensive lotion, after cleansing
- When
- 10-day course
- Texture
- Liquid lotion, cotton-pad application
- Suits
- Thin-to-normal Skin Instants
Choose options

Product details
A closer look.
Biologique Recherche Lotion MC110 N°1 is an intensive plumping and renewing facial lotion designed to refine skin texture while visibly smoothing fine lines and wrinkles. Unlike a traditional hydrating toner, MC110 N°1 combines chemical exfoliation with a targeted plumping action. It helps remove accumulated dead surface skin, smooth irregular-looking texture and improve visible radiance, leaving the skin looking fuller, softer and more refined. Facial contours appear more defined, fine lines look plumped and the complexion appears fresher and smoother. MC110 N°1 is designed to be used as an intensive 10-day course, which makes it less of an everyday toner and more of a targeted Biologique Recherche beauty booster. It is not "another P50": Lotion P50 is part of the regular Initialization Stage, while MC110 N°1 is a short, focused course of exfoliation, renewal and visible plumping.
Why you’ll love it.
We think MC110 N°1 makes the most sense when your routine feels good but your skin seems to have reached a plateau. It is the product we think about when texture could be smoother, forehead lines are more noticeable or the complexion feels a little flat. It is a short, focused course for a more intensive exfoliating and plumping reset, not a replacement for every step of your routine. And because it is active, we don't believe stronger application creates stronger results: use it intentionally.
Pairs well with.
Ingredients, explained.
Explore the formulaFormula note 01
Lactic Acid
An alpha-hydroxy acid that helps encourage exfoliation and smoother-looking skin.
Formula note 02
Salicylic Acid
A beta-hydroxy acid incorporated into the formula's exfoliating complex.
Formula note 03
Niacinamide
Vitamin B3 helps support overall skin quality and visible radiance.
Formula note 04
Vinegar (Acetum)
A characteristic Biologique Recherche ingredient that contributes to the lotion's exfoliating and rebalancing profile.
Formula note 05
Mucor Miehei Extract
An enzymatic ingredient incorporated into the renewing formulation.
Formula note 06
Glycerin & Sodium Lactate
Help support hydration and skin comfort alongside the exfoliating ingredients.
The full formula
How to use
-
01
Use Lotion MC110 N°1 as a 10-day intensive course.
-
02
Generously saturate a cotton pad with the lotion.
-
03
Apply over the face, neck and décolleté using gentle upward dabbing movements.
-
04
Do not rub or scrub the skin aggressively.
-
05
Use cautiously around the eye contour. In case of contact with the eyes, rinse thoroughly with clean water.
-
06
Avoid direct sun exposure immediately after application.
-
07
Do not apply to scratched, irritated or compromised skin.
-
08
Do not use on children under 3 years of age.
-
09
For external use only.
Dab, don't rub: and resist adding other exfoliants during your 10-day course, because more is not automatically better.
Your routine
Cleanse
Cleanse with the Biologique Recherche milk selected for your Skin Instant.
This product
Intensive lotion
Saturate a cotton pad and dab over the face, neck and décolleté with gentle upward movements, for 10 days.
Biologique Recherche Lotion MC110Serum
If prescribed, follow with a targeted serum such as Sérum Élastine.
Biologique Recherche Sérum ÉlastineSerum
Or, if prescribed, Sérum Collagène Originel.
Biologique Recherche Sérum Collagène OriginelCream
Finish with the moisturizer selected for your Skin Instant.
In the morning
Apply a broad-spectrum sunscreen and avoid direct sun exposure right after applying MC110 N°1.
For when your skin has reached a plateau.
When to use it
After the course, your Skin Instant should be reassessed before continuing.
Dabbed on with a cotton pad, never rubbed.
Works well with
The Loshen & Crem experience
The pleasure is in the details.
Thoughtful skincare, from our Edmonton boutique to your daily ritual. Discover carefully chosen dermocosmetic brands, customized samples and the pleasure of a parcel prepared with care.
Knowledge behind the selection.
Our founder’s skincare education experience across Canada shapes how we explain ingredients, textures and the place of each product in a routine.
Samples with you in mind.
Customized samples to complement your order and introduce you to something worth discovering. A little curiosity, beautifully encouraged.
A gift to yourself.
Thoughtful preparation and finishing touches make receiving your skincare part of the pleasure.
A real boutique. A human point of view.
Loshen & Crem is a skincare boutique and facial studio in Edmonton. Our online selection carries that same considered approach.
Your questions, answered.
Is MC110 the same as Lotion P50?
No. Lotion P50 is an ongoing exfoliating and balancing step selected for your Skin Instant. MC110 N°1 is an intensive 10-day beauty booster focused on exfoliation, renewal and visible plumping.
Who is Lotion MC110 N°1 for?
Biologique Recherche currently recommends it for thin-to-normal Skin Instants. Older descriptions linking MC110 to thick skin generally refer to the historical MC110 N°2.
Can I use MC110 every day?
It is recommended as a 10-day intensive course, not as an indefinite daily toner. After the course, your Skin Instant should be reassessed before continuing.
Do I use MC110 before or after Lotion P50?
Biologique Recherche does not give one universal sequence. Because both are active exfoliating lotions, we recommend having the combination personalized.
Can sensitive skin use MC110?
It contains several exfoliating ingredients, including Lactic Acid and Salicylic Acid, so we strongly recommend professional guidance if sensitivity, redness or a compromised barrier are current concerns. Do not apply it to scratched or irritated skin.
Do I need sunscreen while using MC110?
Daily sun protection is always important, and Biologique Recherche advises avoiding direct sun exposure immediately after application.
Does it contain nuts?
Yes. The formula contains ingredients derived from walnut. If you have a nut allergy, please book a consultation with one of our estheticians before purchasing.
Skin Reaction Policy
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.

