Your routine
iS ClinicalSheald Recovery Balm
Why it fits
A rich moisturizer or targeted comfort balm.
iS Clinical Youth Serum
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Explore La Crem rewardsFine lines, texture, all skin types
A weightless peptide gel serum that instantly smooths and tightens the feel of skin, and helps it look firmer over time.
Discover the formula & ingredientsPickup in Edmonton
Usually ready in 24 hours
Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Let’s talk about your skin and what belongs in your routine.
From our boutique to your door
Shipping, on usRegular $149+ · Priority $249+ CAD
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30-day returnsUnopened products · View policy
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Selected with care.
iS Clinical
Youth Serum
Your ritual begins with the right choice.
$274.00 CAD
Taxes calculated at checkout.
The skincare focus
Instantly smoother.
A weightless peptide gel serum that instantly smooths and tightens the feel of skin, and helps it look firmer over time.
Explore our ingredient glossaryiS Clinical
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Tripeptide-1 and Tripeptide-10 Citrulline
Firmer, smoother-looking skin.
Pseudoalteromonas Ferment Extract (Extremozymes®)
Antioxidant care.
Hydrolyzed Wheat and Soy Protein
Instant smoothing feel.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Cleansing Complex, Super Serum Advance+, Youth Serum, moisturizer, sunscreen.
Your routine
iS ClinicalCleansing Complex
Why it fits
The cleansing step, before serums.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
iS Clinical Youth Serum
iS Clinical Youth Serum is a featherlight gel with an immediate smoothing effect.
Peptides, Extremozymes®, plant proteins and vitamins A, C and E help skin look firmer, smoother and more refined.
A beautiful base under makeup.
Why we love it
The instant smoothing feel makes it our favourite before an event.
Benefits
- Instantly smooths
- Firmer-looking skin
- Refines pores and texture
- Antioxidant care
- Smooth makeup base
Best for
Fine lines, texture, all skin types
Apply it before makeup on big days.
How to use
- Morning and/or evening, on clean skin.
- Smooth over face, neck and around the eyes.
- Follow with moisturizer and sunscreen.
Full Ingredient List
Water, PVP, Caffeine, Glycerin, Disodium EDTA, Hydroxyethylcellulose, Ceratonia Siliqua (Locust Bean) Gum, Hydrolyzed Casein, Pseudoalteromonas Ferment Extract, Hydrolyzed Wheat Protein, Hydrolyzed Soy Protein, Tripeptide-10 Citrulline, Tripeptide-1, Lecithin, Butylene Glycol, Xanthan Gum, Carbomer, Triethanolamine, Caprylyl Glycol, Phenoxyethanol, Ahnfeltia Concinna Extract, Beta Vulgaris (Beet) Root Extract [Extrait De Racine De Betterave], Haberlea Rhodopensis Leaf Extract, Faex (Yeast) Extract [Extrait De Levure], Acetyl Tyrosine, Proline, Hydrolyzed Vegetable Protein, Adenosine Triphosphate, Ergothioneine, Saccharide Isomerate, Hydrolyzed Wheat Protein/PVP Crosspolymer, VP/Dimethylaminoethylmethacrylate Copolymer, Phospholipids, Tocopheryl Acetate, Retinyl Palmitate, Ascorbyl Palmitate, Asiaticoside, Asiatic Acid, Madecassic Acid, 1,2-Hexanediol.
Ingredients may be updated by the manufacturer. Please refer to the product packaging for the most current ingredient list.
Shipping & returns
For delivery and return information, view our policy.
A Weightless Serum for Instantly Smoother, Firmer-Looking Skin
iS Clinical Youth Serum is a featherlight gel serum that gives skin an immediate smoothing, tightening feel while helping it look firmer over time. Peptides, Extremozymes®, plant proteins and vitamins A, C and E work together for smoother texture and a more refined look.
Benefits
- Instantly smooths and tightens the feel of skin
- Helps skin look firmer and more elastic
- Helps refine the look of pores and texture
- Antioxidant care against daily environmental stress
- Creates a smooth base under makeup
Best For
- Fine lines and loss of firmness
- Uneven texture and visible pores
- All skin types, including oily skin that wants a light formula
How to Use
- Morning and/or evening, apply a small amount to clean skin.
- Smooth over the face, neck and around the eyes.
- Follow with moisturizer, and sunscreen every morning.
Loshen & Crem’s Recommendation
Youth Serum is lovely before an event: the immediate smoothing effect makes makeup sit beautifully. It layers easily over vitamin C serums such as Super Serum Advance+.
Ingredients
- Copper Tripeptide (Tripeptide-1) and Tripeptide-10 Citrulline: Help skin look firmer and smoother.
- Extremozymes® (Pseudoalteromonas Ferment Extract): Help protect skin from daily environmental stress.
- Wheat and Soy Proteins: Give the immediate smoothing, tightening feel.
- Vitamins A, C and E: Antioxidant care.
- Caffeine: Helps skin look refreshed.
Full Ingredient List
Water, PVP, Caffeine, Glycerin, Disodium EDTA, Hydroxyethylcellulose, Ceratonia Siliqua (Locust Bean) Gum, Hydrolyzed Casein, Pseudoalteromonas Ferment Extract, Hydrolyzed Wheat Protein, Hydrolyzed Soy Protein, Tripeptide-10 Citrulline, Tripeptide-1, Lecithin, Butylene Glycol, Xanthan Gum, Carbomer, Triethanolamine, Caprylyl Glycol, Phenoxyethanol, Ahnfeltia Concinna Extract, Beta Vulgaris (Beet) Root Extract [Extrait De Racine De Betterave], Haberlea Rhodopensis Leaf Extract, Faex (Yeast) Extract [Extrait De Levure], Acetyl Tyrosine, Proline, Hydrolyzed Vegetable Protein, Adenosine Triphosphate, Ergothioneine, Saccharide Isomerate, Hydrolyzed Wheat Protein/PVP Crosspolymer, VP/Dimethylaminoethylmethacrylate Copolymer, Phospholipids, Tocopheryl Acetate, Retinyl Palmitate, Ascorbyl Palmitate, Asiaticoside, Asiatic Acid, Madecassic Acid, 1,2-Hexanediol.
Ingredients may be updated by the manufacturer. Please refer to the product packaging for the most current ingredient list.
Frequently Asked Questions
Is it an oil?
No. It is a light, water-based gel serum.
Does it contain wheat or milk proteins?
Yes. It contains hydrolyzed wheat, soy and casein (milk) proteins.
Where can I buy iS Clinical Youth Serum in Canada?
iS Clinical Youth Serum is available from Loshen & Crem online across Canada and at our Edmonton, Alberta boutique.
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your order01 · Across Canada
A good thing, on its way.
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Tripeptide-1 and Tripeptide-10 Citrulline
Firmer, smoother-looking skin.
Pseudoalteromonas Ferment Extract (Extremozymes®)
Antioxidant care.
Hydrolyzed Wheat and Soy Protein
Instant smoothing feel.
Retinyl Palmitate, Ascorbyl Palmitate and Tocopheryl Acetate
Antioxidant vitamins.
Caffeine
A refreshed look.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore iS Clinical.
Find your place to begin.
Discover iS Clinical Youth Serum at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the iS Clinical collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.