Your routine
Skinbetter ScienceTrio Rebalancing Moisture Treatment
Why it fits
Trio Rebalancing Moisture Treatment layers over both steps to replenish hydration and keep the barrier comfortable while AlphaRet does its work.

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Explore La Crem rewardsDullness, uneven texture, fine lines
A two-step day and night duo for skin showing dullness, uneven texture and fine lines. Alto defends with a broad blend of antioxidants, and AlphaRet renews overnight for smoother, brighter-looking skin.
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The skincare focus
A two-step day and night duo for skin showing dullness, uneven texture and fine lines. Alto defends with a broad blend of antioxidants, and AlphaRet renews overnight for smoother, brighter-looking skin.
Explore our ingredient glossarySkinbetter Science
The ingredients behind this formula—and what they bring to your skin.
Chlorogenic Acids (Alto)
Green coffee polyphenols that anchor Alto's broad antioxidant blend.
Tetrahexyldecyl Ascorbate (Alto, AlphaRet)
A stable, oil-soluble vitamin C that helps brighten and defend the skin.
Superoxide Dismutase (Alto, AlphaRet)
An antioxidant enzyme that helps neutralize free radicals at the skin's surface.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Follow with a moisturizer such as Trio and a daily sunscreen. Avoid other retinoids or exfoliating acids while you introduce AlphaRet.
Your routine
Trio Rebalancing Moisture Treatment layers over both steps to replenish hydration and keep the barrier comfortable while AlphaRet does its work.
Your routine
An exfoliating foam cleanser and the first step of your routine, before serum and moisturizer.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Skinbetter Science Essentials for Signs of Aging pairs Alto Advanced Defense and Repair Serum (15 ml) with AlphaRet Overnight Cream (15 ml), with a travel pouch. It is the brand's foundational day and night ritual in one compact set.
Alto is a silky antioxidant serum with vitamins C and E, coenzyme Q10 and polyphenol-rich extracts such as açaí, turmeric, cocoa, green tea, grape seed and olive. It helps defend the skin against daily environmental stress. AlphaRet Overnight Cream combines a retinoid bonded to lactic acid with glycolic acid, peptides and ceramides to smooth the look of texture, fine lines and uneven tone, with comfort in mind.
Use Alto morning and evening, and AlphaRet in the evening. Because AlphaRet contains a retinoid and alpha hydroxy acids, introduce it gradually if your skin is sensitive and wear a daily sunscreen.
This is one of our favourite pairings for clients who want visible refinement without a long routine. Alto protects during the day, and AlphaRet does the renewing at night. Two steps, two clear roles. We like it as a first serious anti-aging routine and as a reliable foundation to build on.
Dullness, uneven texture, fine lines
Give the duo a steady eight to twelve weeks; consistency matters more than layering more actives.
Alto Advanced Defense and Repair Serum:
Aqua/Water/Eau, Butylene Glycol, Propanediol, Ethylhexyl Olivate, Cetearyl Alcohol, Chlorogenic Acids, Niacinamide, Lauryl Lactate, Dimethyl Isosorbide, Pyrroloquinoline Quinone Allyl Ester, Hydrolyzed Sodium Hyaluronate, Glycyrrhiza Glabra Root Extract / Licorice Root Extract, Tetrahexyldecyl Ascorbate, Ergothioneine, Taraxacum Officinale Rhizome / Root Extract – Dandelion Rhizome/Root Extract, Arabidopsis Thaliana Extract, Carnosine, Camellia Sinensis Leaf Extract, Vitis Vinifera Seed Extract / Grape Seed Extract, Theobroma Cacao Seed Extract / Cocoa Seed Extract, Curcuma Longa Root Extract / Turmeric Root Extract, Olea Europaea Fruit Extract / Olive Fruit Extract, Euterpe Oleracea Fruit Extract, Palmitoyl Tripeptide-1, Buddleja Officinalis Flower Extract, Coffea Arabica Seed Extract / Coffee Seed Extract, Crocus Sativus Callus Extract, Superoxide Dismutase, Ubiquinone, Plankton Extract, Micrococcus Lysate, Arginine, Zingiber Officinale Root Extract / Ginger Root Extract, Ceramide NP, Ceramide AP, Ceramide EOP, Linoleic Acid, Linolenic Acid, Ascorbic Acid, Bisabolol, Tocopherol, Tocopheryl Acetate, Cholesterol, Phytosphingosine, Jojoba Esters, Sodium PCA, Methyl Gluceth-20, Glycerin, Helianthus Annuus Seed Cera / Sunflower Seed Wax, Acacia Decurrens Flower Cera / Acacia Decurrens Flower Wax, Lecithin, Sodium Lauroyl Lactylate, Dicetyl Phosphate, Propanediol Dicaprylate / Caprate, Polyglycerin-3, Ceteth-20 Phosphate, Diisostearyl Malate, Xanthan Gum, Steareth-2, Acacia Senegal Gum, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Maltodextrin, Ricinoleth-40, Sodium Hydroxide, Citric Acid, Sodium Phytate, Ethylhexylglycerin, Phenoxyethanol, Ethylhexyl Palmitate, Alcohol, Lactic Acid, Pentylene Glycol, Sorbitan Isostearate, Tribehenin
AlphaRet Overnight Cream:
Aqua/Water/Eau, Sodium Glycolate, Glycolic Acid, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide NP, Hyaluronic Acid, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii (Shea) Butter, Allantoin Glycyrrhetinic Acid, Sodium PCA, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Tromethamine, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, Titanium Dioxide (CI 77891)
Alto Advanced Defense and Repair Serum (15 ml) and AlphaRet Overnight Cream (15 ml), with a travel pouch.
Alto first, then AlphaRet in the evening, then moisturizer if needed.
Many people do. If your skin is sensitive or new to retinoids, start every second or third evening and increase as your skin is comfortable.
Yes. AlphaRet contains alpha hydroxy acids, so wear a daily sunscreen and limit sun exposure.
AlphaRet contains a retinoid. Speak with your physician before use if you are pregnant, breastfeeding or planning a pregnancy.
For delivery and return information, view our policy.
A two-step day and night duo for skin showing dullness, uneven texture and fine lines. Alto defends with a broad blend of antioxidants, and AlphaRet renews overnight for smoother, brighter-looking skin.
Skinbetter Science Essentials for Signs of Aging pairs Alto Advanced Defense and Repair Serum (15 ml) with AlphaRet Overnight Cream (15 ml), with a travel pouch. It is the brand's foundational day and night ritual in one compact set.
Alto is a silky antioxidant serum with vitamins C and E, coenzyme Q10 and polyphenol-rich extracts such as açaí, turmeric, cocoa, green tea, grape seed and olive. It helps defend the skin against daily environmental stress. AlphaRet Overnight Cream combines a retinoid bonded to lactic acid with glycolic acid, peptides and ceramides to smooth the look of texture, fine lines and uneven tone, with comfort in mind.
Use Alto morning and evening, and AlphaRet in the evening. Because AlphaRet contains a retinoid and alpha hydroxy acids, introduce it gradually if your skin is sensitive and wear a daily sunscreen.
This is one of our favourite pairings for clients who want visible refinement without a long routine. Alto protects during the day, and AlphaRet does the renewing at night. Two steps, two clear roles. We like it as a first serious anti-aging routine and as a reliable foundation to build on.
Alto Advanced Defense and Repair Serum
Aqua/Water/Eau, Butylene Glycol, Propanediol, Ethylhexyl Olivate, Cetearyl Alcohol, Chlorogenic Acids, Niacinamide, Lauryl Lactate, Dimethyl Isosorbide, Pyrroloquinoline Quinone Allyl Ester, Hydrolyzed Sodium Hyaluronate, Glycyrrhiza Glabra Root Extract / Licorice Root Extract, Tetrahexyldecyl Ascorbate, Ergothioneine, Taraxacum Officinale Rhizome / Root Extract – Dandelion Rhizome/Root Extract, Arabidopsis Thaliana Extract, Carnosine, Camellia Sinensis Leaf Extract, Vitis Vinifera Seed Extract / Grape Seed Extract, Theobroma Cacao Seed Extract / Cocoa Seed Extract, Curcuma Longa Root Extract / Turmeric Root Extract, Olea Europaea Fruit Extract / Olive Fruit Extract, Euterpe Oleracea Fruit Extract, Palmitoyl Tripeptide-1, Buddleja Officinalis Flower Extract, Coffea Arabica Seed Extract / Coffee Seed Extract, Crocus Sativus Callus Extract, Superoxide Dismutase, Ubiquinone, Plankton Extract, Micrococcus Lysate, Arginine, Zingiber Officinale Root Extract / Ginger Root Extract, Ceramide NP, Ceramide AP, Ceramide EOP, Linoleic Acid, Linolenic Acid, Ascorbic Acid, Bisabolol, Tocopherol, Tocopheryl Acetate, Cholesterol, Phytosphingosine, Jojoba Esters, Sodium PCA, Methyl Gluceth-20, Glycerin, Helianthus Annuus Seed Cera / Sunflower Seed Wax, Acacia Decurrens Flower Cera / Acacia Decurrens Flower Wax, Lecithin, Sodium Lauroyl Lactylate, Dicetyl Phosphate, Propanediol Dicaprylate / Caprate, Polyglycerin-3, Ceteth-20 Phosphate, Diisostearyl Malate, Xanthan Gum, Steareth-2, Acacia Senegal Gum, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Maltodextrin, Ricinoleth-40, Sodium Hydroxide, Citric Acid, Sodium Phytate, Ethylhexylglycerin, Phenoxyethanol, Ethylhexyl Palmitate, Alcohol, Lactic Acid, Pentylene Glycol, Sorbitan Isostearate, Tribehenin
AlphaRet Overnight Cream
Aqua/Water/Eau, Sodium Glycolate, Glycolic Acid, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide NP, Hyaluronic Acid, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii (Shea) Butter, Allantoin Glycyrrhetinic Acid, Sodium PCA, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Tromethamine, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, Titanium Dioxide (CI 77891)
Please refer to the packaging of your product for the most up-to-date ingredient list.
Sun sensitivity: This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing and limit sun exposure while using this product and for a week afterwards.
Pregnancy and breastfeeding: This product contains a topical retinoid. If you are pregnant, breastfeeding or planning a pregnancy, speak with your physician before use.
Caution: For external use only. Avoid contact with eyes; if contact occurs, rinse thoroughly with water. If irritation persists, discontinue use and consult a physician.
Explore Skinbetter Science at Loshen & Crem, our skin-health boutique and facial studio in Edmonton. We ship across Canada, and our team is happy to help you find the right routine.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
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Speak with our boutique03 · Care you can count on
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Green coffee polyphenols that anchor Alto's broad antioxidant blend.
A stable, oil-soluble vitamin C that helps brighten and defend the skin.
An antioxidant enzyme that helps neutralize free radicals at the skin's surface.
AlphaRet technology, a retinoid bonded to lactic acid, for smoother-looking texture and softer-looking lines.
An alpha hydroxy acid that helps refine the look of rough texture.
A skin-identical lipid that helps reinforce the barrier.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Skinbetter Science Essentials for Signs of Aging at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Skinbetter Science collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
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