Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
Book Your AppointmentSuggestions
Tax excluded. Shipping calculated at checkout
Your ritual, rewarded. Choose your La Crem tier to estimate your points.
Estimated on eligible spend before tax, shipping and discounts. Your account confirms the final balance.
Explore La Crem rewardsAn advanced anti-wrinkle serum formulated with a powerful combination of retinoids and the patented Longevity Complex™ to help renew, smooth, and firm the skin. Featuring encapsulated retinol, retinal, and silybin in phytosomes, this silky serum helps diminish the appearance of fine lines, wrinkles, and loss of firmness while supporting a smoother, more toned complexion.
Discover the formula & ingredientsPickup in Edmonton
Usually ready in 24 hours
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
Wait for your ready-for-pickup email before visiting.
Visit the boutiqueNeed expert guidance?
Let’s talk about your skin and what belongs in your routine.
From our boutique to your door
Selected with care.
[comfort zone]
Your ritual begins with the right choice.
$152.00 CAD
Taxes calculated at checkout.
The skincare focus
An advanced anti-wrinkle serum formulated with a powerful combination of retinoids and the patented Longevity Complex™ to help renew, smooth, and firm the skin. Featuring encapsulated retinol, retinal, and silybin in phytosomes, this silky serum helps diminish the appearance of fine lines, wrinkles, and loss of firmness while supporting a smoother, more toned complexion.
Explore our ingredient glossary[comfort zone]
The ingredients behind this formula—and what they bring to your skin.
Longevity Complex™
A blend of organic superfood extracts and carnosine designed to help counteract the visible effects of environmental stress and lifestyle factors
Retinal
A high-performance retinoid that helps support skin renewal and improve the appearance of wrinkles and uneven texture
Retinol
Helps visibly smooth and refine the skin while improving firmness and elasticity
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Explore another step in your face-care routine.
Your routine
A nourishing, protective cream that comforts, strengthens, and shields sensitive skin — especially those exposed to harsh climates. Its rich, barrier-supportive texture replenishes hydration, reinforces resilience, and helps reduce feelings of tightness or discomfort. Ideal for sensitive, sensitized, dry, or redness-prone skin needing extra protection.
Your routine
An anti-pollution, hydrating, and plumping cleanser designed to gently remove makeup, SPF, impurities, and urban residue while leaving skin feeling soft, radiant, and refreshed. Enriched with the patented Longevity Complex™, this silky foaming cleanser helps support healthier-looking skin while respecting the skin barrier.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
An advanced anti-wrinkle serum formulated with a powerful combination of retinoids and the patented Longevity Complex™ to help renew, smooth, and firm the skin. Featuring encapsulated retinol, retinal, and silybin in phytosomes, this silky serum helps diminish the appearance of fine lines, wrinkles, and loss of firmness while supporting a smoother, more toned complexion.
Aqua / Water / Eau, Glycerin, Pentylene Glycol, Butyrospermum Parkii (Shea) Butter, C9-12 Alkane, Isostearyl Alcohol, Glyceryl Stearate Citrate, Crambe Abyssinica Seed Oil, Butylene Glycol Cocoate, Behenyl Alcohol, Dicaprylyl Ether, Octyldodecyl Myristate, Cellulose Acetate Butyrate, Butylene Glycol, Sorbitan Laurate, Propanediol, Lecithin, Chlorphenesin, Agar, Carnosine, Silybin, Spinacia Oleracea (Spinach) Leaf Extract, Xanthan Gum, Tricaprylin, Myrtus Communis Extract, C14-22 Alcohols, Retinol, Citric Acid, Ethylcellulose, Sodium Phytate, Retinal, Tocopherol, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Tephrosia Purpurea Seed Extract, Glycine Soja (Soybean) Oil, Sodium Benzoate, Potassium Sorbate.
For delivery and return information, view our policy.
An advanced anti-wrinkle serum formulated with a powerful combination of retinoids and the patented Longevity Complex™ to help renew, smooth, and firm the skin. Featuring encapsulated retinol, retinal, and silybin in phytosomes, this silky serum helps diminish the appearance of fine lines, wrinkles, and loss of firmness while supporting a smoother, more toned complexion.
Pair the Comfort Zone Skin Regimen /Lx Retinol Serum with the Skin Regimen /Lx Tripeptide Gel Cream and a daily SPF for a complete nighttime renewal routine focused on smoother, firmer, more radiant-looking skin.
Key Ingredients:
Aqua / Water / Eau, Glycerin, Pentylene Glycol, Butyrospermum Parkii (Shea) Butter, C9-12 Alkane, Isostearyl Alcohol, Glyceryl Stearate Citrate, Crambe Abyssinica Seed Oil, Butylene Glycol Cocoate, Behenyl Alcohol, Dicaprylyl Ether, Octyldodecyl Myristate, Cellulose Acetate Butyrate, Butylene Glycol, Sorbitan Laurate, Propanediol, Lecithin, Chlorphenesin, Agar, Carnosine, Silybin, Spinacia Oleracea (Spinach) Leaf Extract, Xanthan Gum, Tricaprylin, Myrtus Communis Extract, C14-22 Alcohols, Retinol, Citric Acid, Ethylcellulose, Sodium Phytate, Retinal, Tocopherol, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Tephrosia Purpurea Seed Extract, Glycine Soja (Soybean) Oil, Sodium Benzoate, Potassium Sorbate.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
A blend of organic superfood extracts and carnosine designed to help counteract the visible effects of environmental stress and lifestyle factors
A high-performance retinoid that helps support skin renewal and improve the appearance of wrinkles and uneven texture
Helps visibly smooth and refine the skin while improving firmness and elasticity
Milk thistle-derived active that helps support skin renewal and firmness with enhanced stability and bioavailability
Helps nourish and protect the skin
Provides antioxidant support
Helps defend against visible environmental stressors
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Skin Regimen /Lx Retinol Serum at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the [comfort zone] collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
Curious about…
Our team can help you find another option suited to your skin and routine.
Need help choosing? Ask our team.