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Le Mieux24 Hr. Age Defying Cream
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A Loshen & Crem bestseller for lasting moisture, barrier support and smoother, firmer-looking skin

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Explore La Crem rewardsA diamond-infused hyaluronic acid and peptide concentrate for plumper, firmer and more luminous-looking skin
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Le Mieux
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The skincare focus
A diamond-infused hyaluronic acid and peptide concentrate for plumper, firmer and more luminous-looking skin
Explore our ingredient glossaryLe Mieux
The ingredients behind this formula—and what they bring to your skin.
Hya10+ Complex
A combination of 10 hyaluronic acid forms that supports hydration, softness and visible plumpness.
Galactomyces Ferment Filtrate
Conditions the skin and supports a smooth, radiant appearance.
Niacinamide
Supports the moisture barrier while helping improve uneven-looking tone and texture.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
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Your routine
A Loshen & Crem bestseller for lasting moisture, barrier support and smoother, firmer-looking skin
Your routine
A nourishing peptide cleanser for soft, supple and comfortably clean skin
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
A diamond-infused hyaluronic acid and peptide concentrate for plumper, firmer and more luminous-looking skin
Le Mieux Oh My Glow Serum is a concentrated hydrating and brightening treatment designed for use with the Oh My Glow Activator and Le Mieux Ionized Oxygen Infuser. Its Hya10+ Complex combines 10 forms of hyaluronic acid with peptides, niacinamide, tranexamic acid and conditioning oils to support visible plumpness, firmness and a more even-looking complexion.
Ectoin, beta-glucan, panthenol, aloe and bisabolol help keep stressed or dehydrated skin feeling comfortable, while genuine diamond powder and silica create an immediate soft-focus luminosity.
The resulting glow comes from several effects: enhanced surface hydration, temporary plumping of dehydration lines, conditioning ingredients and the light-diffusing finish of diamond powder. It should not be interpreted as permanent volumizing or medical oxygenation.
Galactomyces Ferment Filtrate, Sodium Hyaluronate, Oryza Sativa (Rice) Bran Water, Hyaluronic Acid, Zinc Hydrolyzed Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Dimethylsilanol, Sodium Hyaluronate Crosspolymer, C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Ascorbyl Propyl Hyaluronate (Proprietary Formula), Niacinamide, Tranexamic Acid, Simmondsia Chinensis (Jojoba) Seed Oil, Adansonia Digitata Seed Oil, Citrullus Lanatus (Watermelon) Seed Oil, Propanediol, Aloe Barbadensis Leaf Juice, Phospholipids, Adansonia Digitata Fruit Extract, Glycerin, Palmitoyl Tripeptide-5, Ectoin, Acetyl Hexapeptide-8, Bisabolol, Sodium Carboxymethyl Beta-Glucan, Panthenol, Cetearyl Olivate, Sorbitan Olivate, Calcium Pantothenate, Sodium Ascorbyl Phosphate, Tocopheryl Acetate, Xanthan Gum, Octyldodecanol, Hydroxypropyl Guar, Sodium Phytate, Polyglyceryl-2 Stearate, Octyldodecyl Xyloside, Pyridoxine HCl, Diamond Powder, Maltodextrin, Sodium Starch Octenylsuccinate, Silica, Caprylyl Glycol, Glyceryl Stearate, Xylitylglucoside, Anhydroxylitol, Ethylhexylglycerin, Arginine, Xylitol, Allantoin, Stearyl Alcohol, Undecylenoyl Glycine, Capryloyl Glycine.
Ingredient lists may change. Always refer to the product packaging for the most current ingredient list, particularly if you have allergies or sensitivities. Contact info@loshen.ca if you need help reviewing the formula before purchasing.
For delivery and return information, view our policy.
A diamond-infused hyaluronic acid and peptide concentrate for plumper, firmer and more luminous-looking skin
Le Mieux Oh My Glow Serum is a concentrated hydrating and brightening treatment designed for use with the Oh My Glow Activator and Le Mieux Ionized Oxygen Infuser. Its Hya10+ Complex combines 10 forms of hyaluronic acid with peptides, niacinamide, tranexamic acid and conditioning oils to support visible plumpness, firmness and a more even-looking complexion.
Ectoin, beta-glucan, panthenol, aloe and bisabolol help keep stressed or dehydrated skin feeling comfortable, while genuine diamond powder and silica create an immediate soft-focus luminosity.
The resulting glow comes from several effects: enhanced surface hydration, temporary plumping of dehydration lines, conditioning ingredients and the light-diffusing finish of diamond powder. It should not be interpreted as permanent volumizing or medical oxygenation.
Oh My Glow Serum is particularly well suited to:
Persistent pigmentation, melasma, acne or ongoing redness may require a more targeted skincare plan. Oh My Glow Serum is a cosmetic treatment and should not be presented as a treatment for a medical skin condition.
Oh My Glow Serum is not a conventional facial mist or standalone hyaluronic acid serum. It is a concentrated treatment designed to be blended with the more fluid Oh My Glow Activator before being applied through the Le Mieux Ionized Oxygen Infuser.
The formula combines multi-form hydration, peptides, brightening ingredients, antioxidants, soothing ingredients and light-diffusing diamond powder in one treatment.
Use Oh My Glow Serum with Oh My Glow Activator and the Le Mieux Ionized Oxygen Infuser.
Prepare only what is required for each treatment. Do not leave a prepared mixture stored inside the mini-flask. Clean and maintain the infuser according to the device instructions.
The current Le Mieux product page provides directions for use with the Activator and Ionized Oxygen Infuser. It does not provide separate directions for applying the serum directly from the bottle.
At Loshen & Crem, we recommend Oh My Glow Serum for clients who want an intensive hydration treatment with an immediate dewy finish—particularly before an event or whenever the complexion looks tired, dehydrated or less resilient.
Always combine the serum with Oh My Glow Activator when using the Ionized Oxygen Infuser. The Activator provides the fluid base needed for mist application, while the serum contributes the more concentrated peptides, brightening ingredients, conditioning oils and diamond powder.
Two to four drops are generally sufficient. Adding substantially more may alter the consistency of the mixture or waste product without producing proportionally better results.
Apply the treatment to freshly cleansed skin, then seal in hydration with moisturizer. If discoloration is a primary concern, combine the routine with daily broad-spectrum sunscreen and a professionally selected brightening program rather than relying on this serum alone.
Sensitive skin should begin cautiously with a patch test. Do not apply to broken, freshly resurfaced or recently treated skin unless your skincare professional has approved its use.
For the official Oh My Glow treatment, the Serum and Activator are complementary products rather than substitutes for one another.
The Activator has a fluid texture suited to the infuser, while the Serum contains a more concentrated blend of peptides, oils, brightening ingredients and diamond powder.
Blending a small amount of serum into the Activator allows the formula to be freshly customized for each treatment. The serum should not be poured undiluted into the infuser unless Le Mieux provides different instructions for the specific device being used.
Diamond powder is included primarily for its optical effect. Fine mineral particles can scatter light across the skin’s surface, creating a smoother, more luminous and soft-focus appearance.
This immediate radiance should be distinguished from longer-term improvement in uneven-looking tone. Ingredients such as niacinamide, tranexamic acid and sodium ascorbyl phosphate support a more even-looking complexion with continued use, while diamond powder itself does not permanently fade pigmentation.
The Le Mieux device converts the prepared Activator and Serum mixture into a fine mist for even application.
The term “oxygen infuser” should not be interpreted as medical oxygen therapy. The public product information does not establish that the device increases oxygen levels within living skin tissue or delivers ingredients to a specific skin depth. Loshen & Crem presents it as a device-assisted fine-mist application system.
Hyaluronic acid is a humectant that attracts and holds water. When the outer layers of the skin are better hydrated, the complexion can appear smoother, softer and visibly plumper.
This effect can help diminish the look of dehydration lines, but it is temporary and should not be compared with injectable fillers or permanent facial volumizing.
Full Ingredient List:
Galactomyces Ferment Filtrate, Sodium Hyaluronate, Oryza Sativa (Rice) Bran Water, Hyaluronic Acid, Zinc Hydrolyzed Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Dimethylsilanol, Sodium Hyaluronate Crosspolymer, C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Ascorbyl Propyl Hyaluronate (Proprietary Formula), Niacinamide, Tranexamic Acid, Simmondsia Chinensis (Jojoba) Seed Oil, Adansonia Digitata Seed Oil, Citrullus Lanatus (Watermelon) Seed Oil, Propanediol, Aloe Barbadensis Leaf Juice, Phospholipids, Adansonia Digitata Fruit Extract, Glycerin, Palmitoyl Tripeptide-5, Ectoin, Acetyl Hexapeptide-8, Bisabolol, Sodium Carboxymethyl Beta-Glucan, Panthenol, Cetearyl Olivate, Sorbitan Olivate, Calcium Pantothenate, Sodium Ascorbyl Phosphate, Tocopheryl Acetate, Xanthan Gum, Octyldodecanol, Hydroxypropyl Guar, Sodium Phytate, Polyglyceryl-2 Stearate, Octyldodecyl Xyloside, Pyridoxine HCl, Diamond Powder, Maltodextrin, Sodium Starch Octenylsuccinate, Silica, Caprylyl Glycol, Glyceryl Stearate, Xylitylglucoside, Anhydroxylitol, Ethylhexylglycerin, Arginine, Xylitol, Allantoin, Stearyl Alcohol, Undecylenoyl Glycine, Capryloyl Glycine.
Ingredient lists may change. Always refer to the product packaging for the most current ingredient list, particularly if you have allergies or sensitivities. Contact info@loshen.ca if you need help reviewing the formula before purchasing.
The current official directions are specifically written for use with Oh My Glow Activator and the Le Mieux Ionized Oxygen Infuser. Clients purchasing the serum for the official treatment should have access to both products and the device.
Yes, when following the official infuser directions. The mini-flask is filled halfway with the Activator before two to four drops of the Serum are added.
The current Le Mieux product page does not provide directions for direct application. Loshen & Crem recommends using it with the Activator and Infuser as directed unless Le Mieux confirms another application method.
The Activator is the fluid base used inside the infuser. The Serum is the concentrated treatment containing peptides, brightening ingredients, botanical oils and diamond powder. They are designed to be mixed immediately before application.
Yes. Diamond Powder appears in the current ingredient list.
The intended result is a subtle, luminous and light-diffusing finish rather than a chunky glitter effect. The exact appearance can vary with the amount applied, lighting and individual skin texture.
Diamond powder provides an immediate optical glow but does not permanently fade pigmentation. Niacinamide, tranexamic acid and sodium ascorbyl phosphate are the ingredients in the formula more directly associated with improving uneven-looking tone.
The infuser creates a fine mist for application. It should not be described as medical oxygen therapy, and the public product page does not provide evidence that it raises oxygen levels inside skin tissue.
Palmitoyl tripeptide-5 is used to support firmer, smoother-looking skin, but cosmetic use should not be presented as a guarantee of new collagen production.
No. Hyaluronic acid can temporarily improve visible plumpness by supporting hydration, but the serum is not an injectable filler and does not permanently add facial volume.
The current product page does not specify a treatment frequency. Loshen & Crem recommends beginning once or twice weekly and adjusting according to skin tolerance, the rest of your routine and professional guidance.
No. After misting the freshly prepared mixture onto the skin, allow it to settle and follow with an appropriate moisturizer.
The formula contains several soothing and barrier-supporting ingredients and does not list added fragrance or essential oils. However, it is a complex formula containing multiple active ingredients. Patch test first and introduce it cautiously if your skin is highly reactive.
No fragrance, parfum or essential oils appear in the current ingredient list. This does not guarantee that every individual will tolerate the formula.
Potentially, but the formula contains jojoba, baobab and watermelon seed oils as well as other emollients. These ingredients are not automatically pore-clogging, but individual tolerance varies. Oh My Glow Serum is not an acne treatment.
Niacinamide and tranexamic acid can support a more even-looking complexion, but their concentrations are not disclosed. The serum should not be positioned as a standalone treatment for melasma or persistent pigmentation.
These products may coexist within a routine, but highly active combinations can increase sensitivity. If your skin is reactive, use acids or retinoids on alternate evenings and keep the infuser treatment focused on hydration.
Only with approval from the professional who performed the procedure. Do not apply it to broken or freshly treated skin based solely on general product directions.
The formula does not list a retinoid, but it contains tranexamic acid and several advanced cosmetic ingredients. Pregnancy and breastfeeding data for complete topical formulas are limited. Consult your physician or qualified healthcare provider before use.
Avoid misting directly into the eyes. Keep the eyes closed during facial application and use a dedicated eye product for the immediate eye contour.
The prepared mist may be applied to appropriate body areas according to the device instructions. Avoid mucous membranes, broken skin and direct inhalation of the mist.
The current retail size is 1 oz or 30 mL.
No. Prepare only what you require for the treatment and do not store leftover product inside the mini-flask. Clean the device according to its operating instructions.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
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Speak with our boutique03 · Care you can count on
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
A combination of 10 hyaluronic acid forms that supports hydration, softness and visible plumpness.
Conditions the skin and supports a smooth, radiant appearance.
Supports the moisture barrier while helping improve uneven-looking tone and texture.
Helps reduce the visible appearance of discoloration and uneven tone.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Le Mieux Oh My Glow Serum at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Le Mieux collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
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The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
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