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Le Mieux24 Hr. Age Defying Cream
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A Loshen & Crem bestseller for lasting moisture, barrier support and smoother, firmer-looking skin

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Explore La Crem rewardsA lightweight 10-form hyaluronic acid serum for plumper, smoother and deeply hydrated-looking skin
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Le Mieux
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$55.00 CAD
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The skincare focus
A lightweight 10-form hyaluronic acid serum for plumper, smoother and deeply hydrated-looking skin
Explore our ingredient glossaryLe Mieux
The ingredients behind this formula—and what they bring to your skin.
Sodium Hyaluronate
A sodium salt of hyaluronic acid that attracts moisture and supports visible plumpness.
Hyaluronic Acid
Helps hydrate the skin’s surface and soften dehydration lines.
Zinc Hydrolyzed Hyaluronate
A modified form of hyaluronic acid combined with zinc for hydrating and conditioning benefits.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
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Your routine
A Loshen & Crem bestseller for lasting moisture, barrier support and smoother, firmer-looking skin
Your routine
A nourishing peptide cleanser for soft, supple and comfortably clean skin
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
A lightweight 10-form hyaluronic acid serum for plumper, smoother and deeply hydrated-looking skin
Le Mieux Hyaluronic Serum is an award-winning hydration concentrate formulated with ten forms of hyaluronic acid to replenish moisture without a heavy or greasy finish. Its silky gel texture helps soften dehydration lines, improve visible suppleness and leave the complexion looking smoother, fresher and more luminous.
The formula combines Le Mieux’s Hya10+ Complex with galactomyces ferment filtrate, rice bran water, polyglutamic acid, panthenol and a xylitol-derived moisture complex. Antioxidant-rich green tea, ginkgo biloba and vitamin E complement the hydrating ingredients while supporting a healthier-looking complexion.
Particularly well suited to oily, combination, normal and blemish-prone skin, Hyaluronic Serum can also be used by dry skin when layered beneath a moisturizer. It is a hydration serum—not a replacement for the lipids and protective ingredients found in a complete moisturizer.
Galactomyces Ferment Filtrate, Sodium Hyaluronate, Oryza Sativa (Rice) Bran Water, Hyaluronic Acid, Zinc Hydrolyzed Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Dimethylsilanol, Sodium Hyaluronate Crosspolymer, C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Ascorbyl Propyl Hyaluronate, Tocotrienols, Ginkgo Biloba Leaf Extract, Camellia Sinensis Leaf Extract, Propanediol, Xylitylglucoside, Panthenol, Trigonella Foenum-Graecum Seed Extract, Methyl Gluceth-20, Anhydroxylitol, Xylitol, Hydroxyethylcellulose, Oryza Sativa (Rice) Bran Oil, Tocopherol, Polyglutamic Acid, Pentylene Glycol, Caprylyl Glycol, Ethylhexylglycerin.
Ingredient lists may change. Always refer to the product packaging for the most current ingredient list, particularly if you have allergies or sensitivities. Contact info@loshen.ca if you need help reviewing the formula before purchasing.
For delivery and return information, view our policy.
A lightweight 10-form hyaluronic acid serum for plumper, smoother and deeply hydrated-looking skin
Le Mieux Hyaluronic Serum is an award-winning hydration concentrate formulated with ten forms of hyaluronic acid to replenish moisture without a heavy or greasy finish. Its silky gel texture helps soften dehydration lines, improve visible suppleness and leave the complexion looking smoother, fresher and more luminous.
The formula combines Le Mieux’s Hya10+ Complex with galactomyces ferment filtrate, rice bran water, polyglutamic acid, panthenol and a xylitol-derived moisture complex. Antioxidant-rich green tea, ginkgo biloba and vitamin E complement the hydrating ingredients while supporting a healthier-looking complexion.
Particularly well suited to oily, combination, normal and blemish-prone skin, Hyaluronic Serum can also be used by dry skin when layered beneath a moisturizer. It is a hydration serum—not a replacement for the lipids and protective ingredients found in a complete moisturizer.
Hyaluronic Serum is particularly well suited to:
Dehydration can affect every skin type, including oily skin. Excess oil and insufficient water are not mutually exclusive—skin can absolutely manage to be both shiny and thirsty at the same time.
Hyaluronic Serum contains ten named forms and derivatives of hyaluronic acid rather than relying on a single form. These ingredients differ in molecular structure, size, charge and film-forming behaviour, allowing them to support hydration in complementary ways across the skin’s surface and upper layers.
The formula also combines hyaluronic acid with additional humectants and moisture-supporting ingredients rather than asking one ingredient to do all the work.
Use morning and evening.
After cleansing and toning, apply three to five drops to the face and neck. Gently press the serum into the skin until absorbed.
For best results, apply to slightly damp—not dripping wet—skin and follow with moisturizer. This gives the humectants water to bind while the moisturizer helps reduce subsequent moisture loss.
In the morning, finish with broad-spectrum sunscreen. Avoid direct contact with the eyes.
If the serum feels tacky or begins pilling beneath other products, reduce the amount and allow each layer to absorb before continuing.
This is often the first serum we recommend when someone says, “My skin is oily, so I cannot possibly be dehydrated”—while also describing tightness, flaking or makeup that suddenly looks like it has filed for separation.
Hyaluronic Serum gives the skin water-based hydration without adding a rich or occlusive texture. It is especially useful for combination, oily and blemish-prone clients who avoid moisturizer because they associate hydration with heaviness.
Apply three drops to slightly damp skin and always follow with moisturizer. This step matters even more in Alberta’s dry climate. Hyaluronic acid attracts and holds water, but it does not provide the same protective lipid layer as a cream. Used alone, it may leave very dry skin feeling tight once the water begins to evaporate.
Most clients do not need to layer Hyaluronic Serum with several other hyaluronic acid products. If your toner, treatment serum and moisturizer already contain multiple humectants, adding more is not automatically better. Choose the serum because dehydration is the concern—not because ten sounds more exciting than nine.
For oily or combination skin, choose a lightweight moisturizer. For dry or mature skin, follow with a richer cream to help seal in hydration.
All three products support hydration, but they serve different priorities.
Hyaluronic acid is a humectant—a substance that attracts and binds water. Different forms and molecular weights can behave differently within a cosmetic formula.
Larger forms primarily help create a hydrating film across the surface of the skin. Smaller or hydrolyzed forms may distribute more readily within the upper layers of the stratum corneum. Crosslinked and modified forms can offer different film-forming, adhesion or moisture-retention properties.
This does not mean that a topical hyaluronic serum travels deeply into the dermis or replaces the hyaluronic acid used in injectable fillers. The exact molecular weights and product-specific penetration data are not published on the current Le Mieux product page, so claims that the serum hydrates every “layer” of the skin would be too broad.
Its proven cosmetic role is hydration: helping the skin retain water so it appears smoother, softer and more supple.
Dehydrated skin lacks water, while dry skin lacks sufficient oil or protective lipids. A person can have one concern or both simultaneously.
Hyaluronic Serum primarily addresses dehydration by attracting and holding water. A moisturizer adds emollient and occlusive ingredients that soften the skin and slow moisture loss.
Full Ingredient List:
Galactomyces Ferment Filtrate, Sodium Hyaluronate, Oryza Sativa (Rice) Bran Water, Hyaluronic Acid, Zinc Hydrolyzed Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Dimethylsilanol, Sodium Hyaluronate Crosspolymer, C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Ascorbyl Propyl Hyaluronate, Tocotrienols, Ginkgo Biloba Leaf Extract, Camellia Sinensis Leaf Extract, Propanediol, Xylitylglucoside, Panthenol, Trigonella Foenum-Graecum Seed Extract, Methyl Gluceth-20, Anhydroxylitol, Xylitol, Hydroxyethylcellulose, Oryza Sativa (Rice) Bran Oil, Tocopherol, Polyglutamic Acid, Pentylene Glycol, Caprylyl Glycol, Ethylhexylglycerin.
Ingredient lists may change. Always refer to the product packaging for the most current ingredient list, particularly if you have allergies or sensitivities. Contact info@loshen.ca if you need help reviewing the formula before purchasing.
We recommend it for skin that feels tight, looks dull or shows fine dehydration lines. It is especially useful for oily, combination and blemish-prone clients who need water-based hydration without a rich texture.
Absolutely. Oil describes sebum production, while dehydration describes insufficient water. Oily skin may still feel tight, flaky or uncomfortable and can benefit from a lightweight hydrating serum.
Le Mieux specifically positions it for blemish-prone skin. Its lightweight texture provides hydration without relying on a heavy cream base. It is not an acne treatment and will not clear breakouts on its own.
Yes, but dry skin should follow with a moisturizer containing emollient or barrier-supportive ingredients. Hyaluronic Serum supplies hydration but may not provide enough lipid support by itself.
No. It is a hydrating serum. A moisturizer helps seal in that hydration and reduce water loss, particularly in dry climates or for dry and mature skin.
We prefer applying it to slightly damp skin. The skin should not be dripping wet, as excessive water can dilute the application and encourage pilling.
Yes. Le Mieux recommends applying three to five drops to the face and neck both morning and night.
Yes. The current published ingredient list identifies ten forms or derivatives within Le Mieux’s Hya10+ Complex.
No. The number of hyaluronic acid forms should not be interpreted as ten separate skin layers. They have different structures and cosmetic behaviours, but Le Mieux does not publish product-specific penetration data demonstrating ten distinct depths.
Smaller forms may distribute more readily within the upper stratum corneum than very large hyaluronic acid molecules. It would be inaccurate to say that a cosmetic serum penetrates deeply into the dermis without product-specific evidence.
It can visibly plump dehydration lines by increasing moisture within the skin’s outer layers. It cannot physically fill deeper wrinkles or replace lost facial volume.
No. Injectable hyaluronic acid is placed beneath the skin by a qualified medical professional to create structural volume. A topical serum hydrates the skin’s surface and upper layers.
Yes, but both products contain the Hya10+ Complex. Most clients can choose one according to their primary concern. If using both, apply Hyaluronic Serum first and TGF-β Booster second.
Yes. Hyaluronic Serum does not contain retinol or exfoliating acids and can provide supportive hydration within an active routine. If irritation is already present, pause the product causing the reaction rather than using hydration to push through it.
It may be mixed with a non-SPF foundation, but changing a makeup formula can affect coverage, wear and finish. We prefer applying Hyaluronic Serum first, allowing it to absorb and then applying foundation over properly moisturized skin.
Never mix it directly into sunscreen or an SPF foundation when you rely on that product for sun protection, as mixing may interfere with an even protective film.
Humectants attract water but do not create a complete protective lipid layer. In a very dry environment, applying hyaluronic acid without moisturizer may leave the skin feeling tight. Follow with a cream or lotion suited to your skin type.
Pilling is usually caused by using too much product, applying layers too quickly or combining incompatible textures. Reduce the amount, press rather than rub and allow each layer to settle before continuing.
No parfum, fragrance or essential oil appears in the current published ingredient list. Individual sensitivity to ferments or botanical extracts can still vary.
The fragrance-free published formula may suit many sensitive skin types. Patch test first if your skin is highly reactive, and avoid applying it to actively irritated or broken skin.
Only when approved by the professional who performed the treatment. Hyaluronic Serum is a cosmetic product and is not sterile, so it should not automatically be applied to freshly treated or compromised skin.
The current published formula does not list retinoids or exfoliating acids. However, consult your physician or qualified healthcare provider if you have concerns about introducing any product during pregnancy or breastfeeding.
The care behind your order
A few helpful details, before your next delivery.
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Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
A sodium salt of hyaluronic acid that attracts moisture and supports visible plumpness.
Helps hydrate the skin’s surface and soften dehydration lines.
A modified form of hyaluronic acid combined with zinc for hydrating and conditioning benefits.
A modified hyaluronic acid designed to adhere well to the skin’s surface.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Le Mieux Hyaluronic Serum at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Le Mieux collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
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