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Le Mieux24 Hr. Age Defying Cream
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A Loshen & Crem bestseller for lasting moisture, barrier support and smoother, firmer-looking skin

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Explore La Crem rewardsAn intensive overnight serum for smoother lines, stronger barrier support and deeply replenished skin
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Le Mieux
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$180.00 CAD
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The skincare focus
An intensive overnight serum for smoother lines, stronger barrier support and deeply replenished skin
Explore our ingredient glossaryLe Mieux
The ingredients behind this formula—and what they bring to your skin.
Hya10+ Complex
Supports multi-level hydration, softness and a plumper appearance.
Five Ceramides
Help strengthen the moisture barrier and protect against water loss.
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Helps soften the appearance of expression lines.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Explore another step in your face-care routine.
Your routine
A Loshen & Crem bestseller for lasting moisture, barrier support and smoother, firmer-looking skin
Your routine
A nourishing peptide cleanser for soft, supple and comfortably clean skin
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
An intensive overnight serum for smoother lines, stronger barrier support and deeply replenished skin
Le Mieux Dream Drops Overnight Corrective Serum is a peptide-rich nighttime treatment formulated to support hydration, visible renewal and barrier recovery while the skin rests. It targets expression lines, dehydration, uneven texture and loss of elasticity without relying on retinol or exfoliating acids.
The formula combines Le Mieux’s Hya10+ Complex—10 forms of hyaluronic acid—with five ceramides, cholesterol, squalane and conditioning botanical oils. This layered moisture system helps replenish essential lipids, reduce moisture loss and support a smoother, more resilient-looking complexion by morning.
A specialized neuropeptide, palmitoyl tripeptide-5, ectoin, niacinamide and bioengineered peptides complement the barrier-supporting base. Together, they help soften the appearance of lines while comforting skin affected by dryness and daily environmental stress.
Galactomyces Ferment Filtrate, Sodium Hyaluronate, Oryza Sativa (Rice) Bran Water, Hyaluronic Acid, Zinc Hydrolyzed Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Dimethylsilanol, Sodium Hyaluronate Crosspolymer, C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Ascorbyl Propyl Hyaluronate, Saccharomyces/Rice Ferment Filtrate, Aloe Barbadensis Leaf Juice, Squalane, Oligopeptide-225, Oligopeptide-223, sh-Polypeptide-123, Palmitoyl Tripeptide-5, Methyl Gluceth-20, Citrullus Lanatus (Watermelon) Seed Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Beta-Glucan, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Propanediol, Adansonia Digitata Fruit Extract, Oryza Sativa (Rice) Bran Oil, Hydrogenated Ethylhexyl Olivate, Bisabolol, Glyceryl Oleate Citrate, Ectoin, Niacinamide, Acetyl Glycyl Beta-Alanine, Ceramide NS, Ceramide EOP, Ceramide NP, Phospholipids, Octyldodecanol, Hydrogenated Olive Oil Unsaponifiables, Octyldodecyl Xyloside, Dipotassium Glycyrrhizate, Sphingomonas Ferment Extract, Tocotrienols, Ceramide AS, Ceramide AP, Panthenol, Sclerotium Gum, Hydrogenated Lecithin, Lysolecithin, Glyceryl Stearate, Xanthan Gum, Pullulan, Glycerin, Cholesterol, Tocopherol, Sodium Phytate, Sodium Citrate, Caprylyl Glycol, Ethylhexylglycerin, Undecylenoyl Glycine, Capryloyl Glycine.
Ingredient lists may change. Always refer to the product packaging for the most current ingredient list, particularly if you have allergies or sensitivities. Contact info@loshen.ca if you need help reviewing the formula before purchasing.
For delivery and return information, view our policy.
An intensive overnight serum for smoother lines, stronger barrier support and deeply replenished skin
Le Mieux Dream Drops Overnight Corrective Serum is a peptide-rich nighttime treatment formulated to support hydration, visible renewal and barrier recovery while the skin rests. It targets expression lines, dehydration, uneven texture and loss of elasticity without relying on retinol or exfoliating acids.
The formula combines Le Mieux’s Hya10+ Complex—10 forms of hyaluronic acid—with five ceramides, cholesterol, squalane and conditioning botanical oils. This layered moisture system helps replenish essential lipids, reduce moisture loss and support a smoother, more resilient-looking complexion by morning.
A specialized neuropeptide, palmitoyl tripeptide-5, ectoin, niacinamide and bioengineered peptides complement the barrier-supporting base. Together, they help soften the appearance of lines while comforting skin affected by dryness and daily environmental stress.
Dream Drops is particularly well suited to:
Dream Drops is not a treatment for eczema, rosacea or another inflammatory skin condition. Do not apply it to broken, actively inflamed or significantly irritated skin without professional guidance.
Dream Drops combines three complementary approaches to nighttime skincare: multi-form hydration, lipid barrier support and peptide-based age care.
Unlike a basic hyaluronic acid serum, it contains five ceramides, cholesterol, phospholipids, squalane and botanical oils. Unlike a traditional corrective nighttime serum, it does not rely on retinol or exfoliating acids.
Use every evening.
After cleansing and toning, apply a small amount evenly over the face, neck and décolleté. Gently press or smooth the serum into the skin until absorbed.
Avoid the eyelids, lash line and direct contact with the eyes. Use Eye Revive Firming Cream around the orbital contour.
Follow with moisturizer according to your skin’s needs. Normal or oily skin may find Dream Drops sufficiently conditioning on its own, while dry or mature skin will generally benefit from a cream applied afterward.
If your routine includes retinol or exfoliating acids, introduce Dream Drops separately and alternate the treatments initially.
Dream Drops is an especially thoughtful choice when lines appear more pronounced because the skin is dehydrated, depleted or struggling to retain moisture.
The formula does not simply add water. It combines hyaluronic acids with ceramides, cholesterol, phospholipids and emollient oils to support both hydration and the lipid structure responsible for keeping that moisture within the skin.
Pair Youth Drops with Dream Drops for a balanced day-and-night routine:
For dry or mature skin, follow Dream Drops with Bio Cell Rejuvenating Cream or 24 Hr. Age Defying Cream. Apply Midnight Balm only to particularly dry areas when a more occlusive finish is needed.
If you already use Le Mieux Retinol Serum, alternate the products rather than stacking several complex treatments during the same evening. Dream Drops works beautifully as the barrier-supporting treatment on non-retinol nights.
Dream Drops already contains the complete Hya10+ Complex. A separate hyaluronic acid serum is not essential for most clients.
These three Platinum Pro formulas share a Hya10+ and peptide foundation, but they serve different roles.
A complete routine may use Youth Drops in the morning and Dream Drops at night. Beauty Reset can be reserved for event preparation or substituted when a faster smoothing effect is desired.
Dipeptide Diaminobutyroyl Benzylamide Diacetate is a laboratory-designed peptide used in cosmetic formulas targeting expression-related lines.
It is sometimes compared with injectable neuromodulators because of its intended cosmetic role. However, a topical peptide does not work at the same depth, does not paralyze facial muscles and cannot reproduce the effect of Botox or another injectable treatment.
Its role in Dream Drops is to help soften the visible appearance of expression lines with consistent topical use.
Dream Drops contains:
Ceramides are lipids naturally present within the skin barrier. Together with cholesterol and fatty components, they help maintain moisture and protect against excessive water loss.
Dream Drops pairs all five ceramides with cholesterol, phospholipids, hydrogenated lecithin and emollient oils. This makes it more barrier-focused than a traditional water-based hyaluronic acid serum.
Ectoin is a protective molecule produced by certain microorganisms that live in stressful environmental conditions. In topical skincare, it is used for its hydrating, conditioning and environmental stress-supporting properties.
Ectoin may help improve skin comfort and reduce the visible effects associated with dryness and environmental exposure. It does not treat inflammation as a medical condition.
Dream Drops contains several peptide types:
These ingredients are not living cells, injectable growth factors or medical treatments.
Dream Drops combines 10 forms of hyaluronic acid:
These ingredients support hydration across the skin’s surface and help create a smoother, temporarily plumper appearance. They do not permanently fill wrinkles or replace lost facial volume.
Full Ingredient List:
Galactomyces Ferment Filtrate, Sodium Hyaluronate, Oryza Sativa (Rice) Bran Water, Hyaluronic Acid, Zinc Hydrolyzed Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Dimethylsilanol, Sodium Hyaluronate Crosspolymer, C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Ascorbyl Propyl Hyaluronate, Saccharomyces/Rice Ferment Filtrate, Aloe Barbadensis Leaf Juice, Squalane, Oligopeptide-225, Oligopeptide-223, sh-Polypeptide-123, Palmitoyl Tripeptide-5, Methyl Gluceth-20, Citrullus Lanatus (Watermelon) Seed Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Beta-Glucan, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Propanediol, Adansonia Digitata Fruit Extract, Oryza Sativa (Rice) Bran Oil, Hydrogenated Ethylhexyl Olivate, Bisabolol, Glyceryl Oleate Citrate, Ectoin, Niacinamide, Acetyl Glycyl Beta-Alanine, Ceramide NS, Ceramide EOP, Ceramide NP, Phospholipids, Octyldodecanol, Hydrogenated Olive Oil Unsaponifiables, Octyldodecyl Xyloside, Dipotassium Glycyrrhizate, Sphingomonas Ferment Extract, Tocotrienols, Ceramide AS, Ceramide AP, Panthenol, Sclerotium Gum, Hydrogenated Lecithin, Lysolecithin, Glyceryl Stearate, Xanthan Gum, Pullulan, Glycerin, Cholesterol, Tocopherol, Sodium Phytate, Sodium Citrate, Caprylyl Glycol, Ethylhexylglycerin, Undecylenoyl Glycine, Capryloyl Glycine.
Ingredient lists may change. Always refer to the product packaging for the most current ingredient list, particularly if you have allergies or sensitivities. Contact info@loshen.ca if you need help reviewing the formula before purchasing.
Dream Drops is a peptide, hyaluronic acid and ceramide serum formulated for nightly use. It targets dehydration, expression lines, uneven texture, loss of elasticity and visible barrier depletion.
No retinol or another retinoid appears in the published ingredient list.
It is an option for clients who want age-supportive skincare without retinol, but it does not work through the same vitamin A pathway and should not be presented as equivalent to retinol.
Yes. Le Mieux directs Dream Drops for nightly use. Highly reactive skin may begin every other evening and increase gradually.
No glycolic, lactic or salicylic acid appears in the published formula. Dream Drops supports hydration, barrier function and visible renewal without being positioned as an exfoliating treatment.
Dipeptide Diaminobutyroyl Benzylamide Diacetate is a laboratory-designed peptide intended to soften the appearance of expression-related lines.
No. It cannot reproduce the depth, strength or mechanism of an injectable neuromodulator. It is a cosmetic topical peptide that supports a smoother-looking complexion.
Its five ceramides, cholesterol, phospholipids, squalane and emollient oils support the moisture barrier and help reduce water loss. It cannot repair every cause of a clinically compromised barrier or replace medical treatment.
Yes. Its combination of hyaluronic acids, ceramides, cholesterol and oils makes it particularly appropriate for dehydrated or dry skin. Follow with moisturizer for additional nourishment.
Le Mieux lists Dream Drops for oily through dry skin. However, it contains squalane and several botanical oils, so highly congestion-prone skin should patch test and introduce it gradually.
The formula contains no added fragrance according to the published INCI and includes several comforting ingredients. Because it contains many peptides and ferments, highly reactive skin should still patch test.
Ectoin, beta-glucan, bisabolol, panthenol and dipotassium glycyrrhizate may help calm the appearance of mild redness and visible stress. Dream Drops is not a treatment for rosacea or another inflammatory skin condition.
Yes. Youth Drops is designed for morning use, while Dream Drops is designed for the evening. They create a complementary daytime and nighttime routine.
Layering both is generally unnecessary because each is a complex Hya10+ and peptide treatment. Use Beauty Reset when immediate smoothing is the priority and Dream Drops when nighttime barrier support is needed.
We recommend alternating them initially. Use Dream Drops on non-retinol evenings to support hydration and barrier comfort. Combining several complex treatments in one routine is not always better.
It may be used on separate evenings from exfoliating acids. Avoid layering the products when the skin is dry, peeling or irritated.
Once your skin tolerates Perfect Renewal well, Dream Drops may be applied afterward for hydration. Sensitive or acid-naive skin should initially use them on separate evenings.
Possibly for oily or normal skin, depending on comfort. Dry and mature skin will generally benefit from moisturizer applied afterward.
Avoid applying directly onto the eyelids or close to the lash line. Use Eye Revive Firming Cream around the orbital contour.
Dream Drops contains several laboratory-created sh-oligopeptides and sh-polypeptides that Le Mieux categorizes as growth-factor peptides. They are cosmetic signaling ingredients, not living cells or injectable treatments.
No exosomes are identified in the published ingredient list. Dream Drops should not be marketed as an exosome product.
No parfum, added fragrance or essential oils appear in the current published ingredient list. Fermented and botanical ingredients may still give the formula a natural scent.
Purging is not expected because the formula does not contain a retinoid or conventional exfoliating acid. New breakouts are more likely related to individual intolerance or the formula’s emollient ingredients.
No retinoid is listed, but pregnancy and breastfeeding safety information for specialized cosmetic peptides remains limited. Consult your physician or qualified healthcare provider before use.
Only when the treatment provider confirms that the skin is ready for regular skincare. Do not apply it to broken, actively peeling or significantly irritated skin.
Hydration, softness and surface smoothness may be noticed relatively quickly. Changes in the appearance of expression lines, texture and elasticity require consistent use. Le Mieux does not publish a finished-product clinical timeline on its public product page.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
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Speak with our boutique03 · Care you can count on
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Supports multi-level hydration, softness and a plumper appearance.
Help strengthen the moisture barrier and protect against water loss.
Helps soften the appearance of expression lines.
Complement the ceramides and support barrier resilience.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Le Mieux Dream Drops Overnight Corrective Serum at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Le Mieux collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.
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