Your routine
EsthedermIntensive Hyaluronic+ Cream
Why it fits
A smoothing face cream designed to visibly reduce the appearance of wrinkles and fine lines while supporting skin’s hydration and plumpness.
AGE PROTEOM™ Advanced Serum
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Explore La Crem rewardsA high-performance serum designed to help lastingly preserve skin’s youthfulness while supporting faster recovery and improved resilience against daily stressors.
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Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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From our boutique to your door
Shipping, on usRegular $149+ · Priority $249+ CAD
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Selected with care.
Esthederm
AGE PROTEOM™ Advanced Serum
Your ritual begins with the right choice.
Taxes calculated at checkout.
The skincare focus
AGE PROTEOM™ Advanced Serum
A high-performance serum designed to help lastingly preserve skin’s youthfulness while supporting faster recovery and improved resilience against daily stressors.
Explore our ingredient glossaryEsthederm
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Meadowfoam seed oil
A botanical emollient that helps keep skin feeling soft and supple.
Glycerin
A humectant that helps attract moisture and keep skin feeling hydrated.
Propanediol
A humectant and solvent that helps distribute ingredients and maintain a comfortable skin feel.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Explore another step in your face-care routine.
Your routine
EsthedermOsmopure Cleansing Micellar Water
Why it fits
A 3-in-1 micellar water that effortlessly removes makeup, cleanses, and tones in one calming sweep. Infused with Esthederm’s signature Cellular Water and soothing botanicals, this multitasking formula respects the skin’s natural balance while leaving it fresh, soft, and comforted. No rinsing required—just a radiant reset.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
AGE PROTEOM™ Advanced Serum
A high-performance serum designed to help lastingly preserve skin’s youthfulness while supporting faster recovery and improved resilience against daily stressors.
Powered by Esthederm’s patented Age Proteom™ biotechnology and Cellular Water, this advanced formula helps protect and strengthen the skin’s proteome — a key factor in maintaining skin quality over time. By supporting the skin’s natural self-repair mechanisms and providing broad-spectrum antioxidant protection, the serum helps skin look visibly regenerated, more resilient, and youthful. With continued use, skin appears better protected and recovers more efficiently from external aggressors.
Benefits
- Helps visibly reduce the signs of ageing over time
- Supports skin’s natural self-repair and recovery processes
- Helps protect against external stressors
- Improves overall skin quality and resilience
- Skin appears smoother, stronger, and more youthful-looking
How to use
- Unscrew the bottle; the pipette fills automatically
- Apply the amount contained in the pipette (approximately 5 drops) to the face, neck, and décolleté
- Use morning and evening
- To close, screw the lid back on until it clicks
Full Ingredient List
Aqua/Water/Eau*, Glycerin, Isononyl Isononanoate, Propanediol, Limnanthes Alba (Meadowfoam) Seed Oil, Xylose, 1,2-Hexanediol, Cellulose, Dipalmitoyl Hydroxyproline, C20-22 Alkyl Phosphate, C20-22 Alcohols, Cetearyl Alcohol, Caprylic/Capric Triglyceride, Caprylyl Glycol, Polyacrylate Crosspolymer-6, Fragrance (Parfum), Sodium Acetylated Hyaluronate, Coco-Glucoside, Xanthan Gum, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Hydroxide, Adenosine, Sodium Citrate*, Sodium Chloride*, Citric Acid*, Aminoethanesulfinic Acid*, Carnosine*, Potassium Chloride*, Sodium Bicarbonate*, Disodium Phosphate*, Tocopherol, Magnesium Sulfate*, Micrococcus Lysate, Potassium Phosphate*, Calcium Chloride*. [ES249]
*Eau Cellulaire / Cellular Water
Shipping
For delivery and return information, view our policy.
A high-performance serum designed to help lastingly preserve skin’s youthfulness while supporting faster recovery and improved resilience against daily stressors.
Powered by Esthederm’s patented Age Proteom™ biotechnology and Cellular Water, this advanced formula helps protect and strengthen the skin’s proteome — a key factor in maintaining skin quality over time. By supporting the skin’s natural self-repair mechanisms and providing broad-spectrum antioxidant protection, the serum helps skin look visibly regenerated, more resilient, and youthful. With continued use, skin appears better protected and recovers more efficiently from external aggressors.
Benefits:
- Helps visibly reduce the signs of ageing over time
- Supports skin’s natural self-repair and recovery processes
- Helps protect against external stressors
- Improves overall skin quality and resilience
- Skin appears smoother, stronger, and more youthful-looking
How to Use:
- Unscrew the bottle; the pipette fills automatically
- Apply the amount contained in the pipette (approximately 5 drops) to the face, neck, and décolleté
- Use morning and evening
- To close, screw the lid back on until it clicks
Loshen & Crem’s Recommendation:
Ideal for clients looking to support long-term skin quality and resilience rather than quick-fix results. Pair with a protective daytime cream and a barrier-supporting moisturizer at night to reinforce skin recovery and defence.
Ingredients:
Key Ingredients:
Age Proteom™ Patented Biotechnology: Helps protect and strengthen the skin’s proteome while supporting resilience and self-repair
Cellular Water: Biomimetic water that supports cellular energy, balance, and antioxidant protection
Micrococcus Lysate: Supports skin recovery from environmental stress
Carnosine: Antioxidant peptide that helps protect against oxidative stress
Full Ingredients List:
Aqua/Water/Eau*, Glycerin, Isononyl Isononanoate, Propanediol, Limnanthes Alba (Meadowfoam) Seed Oil, Xylose, 1,2-Hexanediol, Cellulose, Dipalmitoyl Hydroxyproline, C20-22 Alkyl Phosphate, C20-22 Alcohols, Cetearyl Alcohol, Caprylic/Capric Triglyceride, Caprylyl Glycol, Polyacrylate Crosspolymer-6, Fragrance (Parfum), Sodium Acetylated Hyaluronate, Coco-Glucoside, Xanthan Gum, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Hydroxide, Adenosine, Sodium Citrate*, Sodium Chloride*, Citric Acid*, Aminoethanesulfinic Acid*, Carnosine*, Potassium Chloride*, Sodium Bicarbonate*, Disodium Phosphate*, Tocopherol, Magnesium Sulfate*, Micrococcus Lysate, Potassium Phosphate*, Calcium Chloride*. [ES249]
*Eau Cellulaire / Cellular Water
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your order01 · Across Canada
A good thing, on its way.
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Meadowfoam seed oil
A botanical emollient that helps keep skin feeling soft and supple.
Glycerin
A humectant that helps attract moisture and keep skin feeling hydrated.
Propanediol
A humectant and solvent that helps distribute ingredients and maintain a comfortable skin feel.
Caprylic/capric triglyceride
An emollient that gives formulas a smooth glide and helps soften skin.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book your consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore Esthederm.
Find your place to begin.
Discover AGE PROTEOM™ Advanced Serum at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Esthederm collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.