Your routine
Skinbetter ScienceAlto Advanced Defense and Repair Serum
Why it fits
Alto Advanced follows LINES with broad antioxidant care for the whole face, so targeted and overall care work together.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsVisible expression lines
A targeted treatment for anyone who wants focused care for specific expression lines. Hyaluronic acid, peptides and vitamin C help hydrate and visibly smooth the forehead, crow's feet, upper lip and smile lines.
Discover the formula & ingredientsPickup in Edmonton
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Skinbetter Science
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$210.00 CAD
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The skincare focus
A targeted treatment for anyone who wants focused care for specific expression lines. Hyaluronic acid, peptides and vitamin C help hydrate and visibly smooth the forehead, crow's feet, upper lip and smile lines.
Explore our ingredient glossarySkinbetter Science
The ingredients behind this formula—and what they bring to your skin.
Sodium Hyaluronate
A form of hyaluronic acid that holds water for a plumper, smoother look.
Acetyl Hexapeptide-8
A peptide that helps soften the look of expression lines.
Tetrahexyldecyl Ascorbate
An oil-soluble vitamin C derivative that offers antioxidant support.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Apply LINES first, then Alto Advanced or Mystro, then your Trio moisturizer.
Your routine
Alto Advanced follows LINES with broad antioxidant care for the whole face, so targeted and overall care work together.
Your routine
Your daily moisturizer, applied after serums and before sunscreen.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Skinbetter Science InterFuse Intensive Treatment LINES is a targeted treatment for the look of expression lines. You apply it only where you want it: forehead, crow's feet, above the upper lip and along the smile lines.
Its InterFuse Technology is designed to help deliver hyaluronic acid into the skin's surface. Five sizes of hyaluronic acid help hold water for a plumper, smoother look. A blend of peptides, amino acids and vitamin C supports that smoothing effect.
It is the first step after cleansing, followed by the rest of your routine. A small 15 ml tube goes a long way, since you only treat the areas that matter to you.
Sometimes a routine is working well, and only a few lines need extra attention. LINES lets you focus there without changing everything else. We like it for its precision and its light, easy layering. It is a simple add-on for clients who want targeted care.
Visible expression lines
Apply it with your ring finger and a light pressing motion, following the direction of each line.
Aqua/Water, C12-15 Alkyl Benzoate, Glycerin, PEG-16 Macadamia Glycerides, Dimethicone, Acetyl Glucosamine, Alcohol Denat., Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Citrate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Glycine, Hydroxyproline, Proline, Acetyl Hexapeptide-8, Hexapeptide-48 HCl, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Sodium Acetylated Hyaluronate, Pisum Sativum (Pea) Extract, Glycine Soja (Soybean) Seed Extract, Glucosamine HCl, Ophiopogon Japonicus Root Extract, Bambusa Vulgaris Leaf/Stem Extract, Hydrolyzed Lupine Protein, Oleic Acid, Sorbitan Isostearate, C18-36 Acid Glycol Ester, PEG-7 Trimethylolpropane Coconut Ether, Sorbitan Laurate, Hexylene Glycol, Polyisobutene, C18-36 Acid Triglyceride, Carbomer, Acrylates Copolymer, Citric Acid, Caprylyl Glycol, Ethylhexylglycerin, Potassium Sorbate, Phenoxyethanol
No. It is a targeted treatment. Continue with a moisturizer suited to your skin.
Only on the areas you want to focus on, such as the forehead, crow's feet, upper lip and smile lines.
Yes, on the crow's feet area, but avoid direct contact with the eyes.
Before. Apply LINES first after cleansing, then your other serums.
Yes. It is formulated without fragrance, parabens or dyes, and it is non-comedogenic.
For delivery and return information, view our policy.
A targeted treatment for anyone who wants focused care for specific expression lines. Hyaluronic acid, peptides and vitamin C help hydrate and visibly smooth the forehead, crow's feet, upper lip and smile lines.
Skinbetter Science InterFuse Intensive Treatment LINES is a targeted treatment for the look of expression lines. You apply it only where you want it: forehead, crow's feet, above the upper lip and along the smile lines.
Its InterFuse Technology is designed to help deliver hyaluronic acid into the skin's surface. Five sizes of hyaluronic acid help hold water for a plumper, smoother look. A blend of peptides, amino acids and vitamin C supports that smoothing effect.
It is the first step after cleansing, followed by the rest of your routine. A small 15 ml tube goes a long way, since you only treat the areas that matter to you.
Sometimes a routine is working well, and only a few lines need extra attention. LINES lets you focus there without changing everything else. We like it for its precision and its light, easy layering. It is a simple add-on for clients who want targeted care.
Aqua/Water, C12-15 Alkyl Benzoate, Glycerin, PEG-16 Macadamia Glycerides, Dimethicone, Acetyl Glucosamine, Alcohol Denat., Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Citrate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Glycine, Hydroxyproline, Proline, Acetyl Hexapeptide-8, Hexapeptide-48 HCl, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Sodium Acetylated Hyaluronate, Pisum Sativum (Pea) Extract, Glycine Soja (Soybean) Seed Extract, Glucosamine HCl, Ophiopogon Japonicus Root Extract, Bambusa Vulgaris Leaf/Stem Extract, Hydrolyzed Lupine Protein, Oleic Acid, Sorbitan Isostearate, C18-36 Acid Glycol Ester, PEG-7 Trimethylolpropane Coconut Ether, Sorbitan Laurate, Hexylene Glycol, Polyisobutene, C18-36 Acid Triglyceride, Carbomer, Acrylates Copolymer, Citric Acid, Caprylyl Glycol, Ethylhexylglycerin, Potassium Sorbate, Phenoxyethanol
Please refer to the packaging of your product for the most up-to-date ingredient list.
Caution: For external use only. Avoid contact with eyes; if contact occurs, rinse thoroughly with water. If irritation persists, discontinue use and consult a physician.
Explore Skinbetter Science at Loshen & Crem, our skin-health boutique and facial studio in Edmonton. We ship across Canada, and our team is happy to help you find the right routine.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
A form of hyaluronic acid that holds water for a plumper, smoother look.
A peptide that helps soften the look of expression lines.
An oil-soluble vitamin C derivative that offers antioxidant support.
A peptide-like ingredient that helps soften the look of expression lines.
A peptide that helps skin look smoother and firmer.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Skinbetter Science InterFuse Intensive Treatment LINES at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Skinbetter Science collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.