Your routine
Biologique RechercheSérum Collagène Originel
Why it fits
The redensifying serum step for visible wrinkles alongside loss of density and plumpness. It goes after your lighter, more fluid serums and before your moisturizer.

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsSkin Instants lacking tone
A targeted structure and fullness serum for Skin Instants lacking tone. Its instant tightening effect helps facial contours look more defined, from the cheeks to the jawline and neck.
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Biologique Recherche
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$336.00 CAD
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The skincare focus
A targeted structure and fullness serum for Skin Instants lacking tone. Its instant tightening effect helps facial contours look more defined, from the cheeks to the jawline and neck.
Explore our ingredient glossaryBiologique Recherche
The ingredients behind this formula—and what they bring to your skin.
Pseudoalteromonas Ferment Extract
A marine-derived ferment extract included to help skin look firmer and smoother.
Secale Cereale (Rye) Seed Extract & Paeonia Albiflora (Peony) Root Extract
Botanical extracts included to help skin look plumper and more toned.
Tapioca Starch & Alteromonas Ferment Extract
Help create the serum's instant tightening effect on the skin's surface.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Cleanse and apply the Lotion P50 selected for your Skin Instant, then Sérum Matriciel Visage. If skin lacks bounce, use it with Sérum Collagène Originel. If skin feels dry as well as less firm, follow with Crème PTO Métamorphique; if the neck and jawline are your main concern, pair it with Crème Splendide. Finish with sunscreen in the morning. These pairings are suggestions; your routine should be personalized to your Skin Instant.
Your routine
The redensifying serum step for visible wrinkles alongside loss of density and plumpness. It goes after your lighter, more fluid serums and before your moisturizer.
Your routine
The daily structural cream step, applied after your serum. Where VG Tensil or Sérum Matriciel Visage provide the targeted serum step, PTO Métamorphique finishes the routine with firming, tautening moisturizing care focused on the facial oval, jawline and neck.
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
Over time, the face can start to look less defined: the cheeks look less full, and the jawline, jowls and neck look less firm.
Biologique Recherche Sérum Matriciel Visage is a targeted serum designed to help the face look more structured and its contours look fuller. Its instant tightening effect helps skin look more toned and visibly reduces the signs of aging across the face, cheeks, jowls, jawline and neck.
Its formula combines a marine-derived ferment, rye seed and peony root extracts, tapioca starch, sodium hyaluronate and peptides to help skin look firmer, plumper and more resilient.
We reach for Sérum Matriciel Visage when a client notices that the skin around the jawline or cheeks looks less firm than usual. It gives an immediate tightening effect without leaving the skin feeling dry. We also like it before any visible sagging, as a simple daily step to keep facial contours looking more sculpted.
Skin Instants lacking tone
Use light upward strokes over the jawline and neck, and keep going until the serum is completely absorbed.
WATER (AQUA), GLYCERIN, BUTYLENE GLYCOL, PENTYLENE GLYCOL, MANNITOL, SODIUM POLYACRYLATE, PSEUDOALTEROMONAS FERMENT EXTRACT, TAPIOCA STARCH, PHENOXYETHANOL, SORBITAN LAURATE, SECALE CEREALE (RYE) SEED EXTRACT, RHIZOBIAN GUM, SODIUM HYALURONATE, PAEONIA ALBIFLORA ROOT EXTRACT, OPUNTIA FICUS-INDICA STEM EXTRACT, ALTEROMONAS FERMENT EXTRACT, ACETYL DIPEPTIDE-1 CETYL ESTER, HYDROXYETHYLCELLULOSE, SALICYLIC ACID, CAPRYLYL GLYCOL, POLYGONUM AVICULARE EXTRACT, ACETYL TETRAPEPTIDE-2, ACETYL TETRAPEPTIDE-11, CHLORPHENESIN, ETHYLHEXYLGLYCERIN, POTASSIUM SORBATE, SODIUM BENZOATE, SODIUM HYDROXIDE.
It provides an instant tightening effect and helps the face look more structured, with fuller-looking cheeks and more defined-looking contours from the cheeks to the jawline and neck.
It is designed for Skin Instants lacking tone, including skin that looks looser than usual around the jawline or cheeks.
It gives an immediate tightening effect without leaving the skin feeling dry.
Apply all over the cleansed face, neck and décolleté using light upward strokes until the serum is completely absorbed.
Avoid contact with the eyes and mucous membranes, avoid sun exposure immediately after application and wear your daily sunscreen. Do not use on children under 3. For external use only.
Sérum Collagène Originel if skin lacks bounce, Crème PTO Métamorphique if skin also feels dry, or Crème Splendide if the neck and jawline are your main concern.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
For delivery and return information, view our policy.
Over time, the face can start to look less defined: the cheeks look less full, and the jawline, jowls and neck look less firm.
Biologique Recherche Sérum Matriciel Visage is a targeted serum designed to help the face look more structured and its contours look fuller. Its instant tightening effect helps skin look more toned and visibly reduces the signs of aging across the face, cheeks, jowls, jawline and neck.
Its formula combines a marine-derived ferment, rye seed and peony root extracts, tapioca starch, sodium hyaluronate and peptides to help skin look firmer, plumper and more resilient.
WATER (AQUA), GLYCERIN, BUTYLENE GLYCOL, PENTYLENE GLYCOL, MANNITOL, SODIUM POLYACRYLATE, PSEUDOALTEROMONAS FERMENT EXTRACT, TAPIOCA STARCH, PHENOXYETHANOL, SORBITAN LAURATE, SECALE CEREALE (RYE) SEED EXTRACT, RHIZOBIAN GUM, SODIUM HYALURONATE, PAEONIA ALBIFLORA ROOT EXTRACT, OPUNTIA FICUS-INDICA STEM EXTRACT, ALTEROMONAS FERMENT EXTRACT, ACETYL DIPEPTIDE-1 CETYL ESTER, HYDROXYETHYLCELLULOSE, SALICYLIC ACID, CAPRYLYL GLYCOL, POLYGONUM AVICULARE EXTRACT, ACETYL TETRAPEPTIDE-2, ACETYL TETRAPEPTIDE-11, CHLORPHENESIN, ETHYLHEXYLGLYCERIN, POTASSIUM SORBATE, SODIUM BENZOATE, SODIUM HYDROXIDE.
At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required.
In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern.
If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
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Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
A marine-derived ferment extract included to help skin look firmer and smoother.
Botanical extracts included to help skin look plumper and more toned.
Help create the serum's instant tightening effect on the skin's surface.
A form of hyaluronic acid that hydrates the upper layers of the epidermis.
Peptides included to help skin look firmer and more resilient.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Biologique Recherche Sérum Matriciel Visage at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Biologique Recherche collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.