


Lotion P50 PIGM 400
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BRIGHTENING + ANTI-DARK SPOT EXFOLIATING LOTION
Biologique Recherche Lotion P50 PIGM 400 is an exfoliating and brightening facial lotion designed specifically for dull-looking Skin Instants with uneven pigmentation and visible dark spots.
It combines the exfoliating philosophy of the iconic Lotion P50 with brightening and antioxidant ingredients selected to support a more even-looking complexion.
By helping remove accumulated pigmented surface cells while supporting the skin against oxidative stress, Lotion P50 PIGM 400 helps visibly reduce the appearance of dark spots, refine uneven texture and restore luminosity.
With consistent use, the complexion appears smoother, brighter and more even.
Skin Instant:
Recommended for Skin Instants that appear dull with uneven pigmentation.
Particularly suited to skin experiencing:
- Visible dark spots
- Uneven-looking pigmentation
- Post-blemish discoloration
- Sun-associated pigmentation
- A dull or lacklustre complexion
- Uneven skin tone
- Surface texture that appears less refined
- A desire for gentle, progressive exfoliation alongside a pigmentation-focused routine
Biologique Recherche currently also identifies Lotion P50 PIGM 400 as an ideal option for those beginning with Lotion P50.
Benefits:
- Gently exfoliates accumulated surface cells
- Helps visibly reduce the appearance of dark spots
- Supports a more even-looking complexion
- Improves visible radiance and luminosity
- Helps refine uneven skin texture
- Provides antioxidant support
- Helps limit oxidative stress associated with visible pigmentation
- Purifies and refreshes the complexion
- Helps prepare the skin for the targeted serums and creams that follow
Why Do Dark Spots Form?
Melanin is the pigment responsible for giving skin its colour.
Its production is a normal and essential biological process, but different factors can cause pigmentation to become uneven or more visible in certain areas.
These can include:
- Sun exposure
- Previous blemishes or inflammation
- Hormonal influences
- Repeated environmental stress
- Changes that occur over time
The result may appear as:
- Brown spots
- Uneven patches
- Post-blemish marks
- A complexion that looks less uniform
Pigmentation is also rarely a surface-only concern.
This is why an effective routine generally needs to address both the visible accumulation of pigmented surface cells and the processes contributing to uneven pigmentation over time.
Lotion P50 PIGM 400 does this through a combination of exfoliating acids, brightening ingredients and antioxidant support.
How Does Lotion P50 PIGM 400 Work?
There are two important parts to its approach.
1. Exfoliation
Lotion P50 PIGM 400 contains several exfoliating acids, including:
- Lactic Acid
- Mandelic Acid
- Gluconolactone
- Salicylic Acid
- Phytic Acid
- Citric Acid
These help encourage the removal of accumulated surface cells so skin appears smoother, clearer and more refined.
2. Pigmentation + antioxidant support
Ingredients including Niacinamide, Wasabi Root Ferment, Palmaria Palmata Extract, Vitamin C and targeted botanical extracts help support a brighter, more uniform-looking complexion while limiting oxidative stress.
The result is not simply exfoliated skin.
The goal is progressively brighter, smoother and more even-looking skin.
Visible Results
In Biologique Recherche's current use evaluation:
- 80% of participants reported a more purified complexion
- 70% reported more beautiful, smoother and more exfoliated-looking skin
- 65% noticed a more even-looking complexion
How to Use:
During the first week:
- Moisten a cotton pad with water, then apply Lotion P50 PIGM 400 to the damp cotton pad.
- Gently dab over the face, neck and décolleté using upward movements.
After the first week:
Apply Lotion P50 PIGM 400 directly onto a dry cotton pad and continue using gentle upward dabbing movements.
- Do not rub or aggressively scrub the skin.
- Avoid the eye contour area.
- Do not use on scratched or irritated skin.
- Do not use during treatment with retinoic acid.
- Avoid direct sun exposure immediately after application.
- Do not use on children under 3 years of age.
- For external use only.
Loshen & Crem’s Recommendation:
P50 PIGM 400 is one of the Biologique Recherche lotions we reach for when a client tells us:
- “My skin looks dull and uneven.”
- “Every blemish leaves a dark mark behind.”
- “I have brown spots that seem to become more noticeable over time.”
- “I want P50, but pigmentation is one of my biggest concerns.”
- “I want brighter skin, but I don't want to simply exfoliate more aggressively.”
That last one matters.
Pigmentation does not need to be attacked.
And more exfoliation does not automatically create a more even complexion.
We prefer P50 PIGM 400 because it combines controlled exfoliation + pigmentation-focused ingredients + antioxidant support within one step.
The goal isn't lighter skin.
The goal is your skin tone, more even.
Lotion P50 PIGM 400 vs. Other Lotion P50 Formulas
All Lotion P50 formulas belong to the same Biologique Recherche methodology, but they are selected according to different Skin Instants.
Choose Lotion P50 PIGM 400 when your primary concerns include:
- Uneven pigmentation
- Dark spots
- Dullness
- Post-blemish discoloration
- A desire for brightening alongside exfoliation
Other Lotion P50 formulas may be more appropriate when the priority is instead:
- Sebum and oiliness
- Dehydration
- Skin lacking tone
- Other specific Skin Instant concerns
In the simplest terms:
P50 PIGM 400 = exfoliation + dark spots + radiance
If pigmentation is the reason you're reaching for P50, this is the formula we want to discuss first.
Lotion P50 PIGM 400 vs. Sérum PIGM 400
They belong beautifully within the same pigmentation-focused routine, but they do different jobs.
Lotion P50 PIGM 400 is the exfoliating preparation step.
It focuses on:
- Surface-cell renewal
- Exfoliation
- Brightness
- Uneven pigmentation
- Preparing the epidermis for treatment
Sérum PIGM 400 is the targeted serum step.
It is designed more specifically around:
- Visible pigmentation marks
- Uneven tone
- Brightening
- Ongoing pigmentation-focused treatment
Think:
- Lotion P50 PIGM 400 → exfoliate + prepare + brighten
- Sérum PIGM 400 → targeted pigmentation treatment
For Skin Instants where pigmentation is a significant concern, the two can complement one another within a personalized routine.
Lotion P50 PIGM 400 vs. Iso-Placenta
This distinction becomes especially important when the dark mark appeared after a blemish.
Choose Lotion P50 PIGM 400 when your concerns are broader:
- Uneven pigmentation
- Brown spots
- Dullness
- Post-blemish discoloration
- Surface texture
Choose Iso-Placenta when the bigger concern is:
- The visible aftermath of blemishes
- Post-acne marks
- Redness left behind after inflammation
- Uneven skin microrelief
- Skin restoration
Think:
- P50 PIGM 400 → pigmentation + exfoliation
- Iso-Placenta → post-blemish restoration + marks
They may also complement one another when post-acne pigmentation and uneven texture occur together.
Is P50 PIGM 400 a Skin-Lightening Product?
We would not describe it that way.
Biologique Recherche describes P50 PIGM 400 as a brightening and anti-dark spot lotion designed to improve uneven pigmentation.
At Loshen & Crem, our goal is not to make someone's natural skin tone lighter.
The goal is to help reduce the visible contrast created by unwanted dark spots and uneven pigmentation so the complexion appears more uniform, luminous and balanced.
Ingredients:
- Niacinamide: Vitamin B3 helps improve visible radiance and support a more even-looking complexion.
- Lactic Acid: An alpha-hydroxy acid that helps exfoliate accumulated surface cells and refine texture.
- Mandelic Acid: An AHA incorporated into the formula's progressive exfoliating complex.
- Gluconolactone: A polyhydroxy acid that provides exfoliating and skin-conditioning support.
- Salicylic Acid & Sodium Salicylate: Salicylates included within the purifying and exfoliating formula.
- Lactobacillus/Wasabia Japonica Root Ferment Extract: Wasabi-derived ferment incorporated into the pigmentation-focused complex.
- Palmaria Palmata Extract: A red algae-derived botanical ingredient included within the brightening formulation.
- Ascorbic Acid: Vitamin C provides antioxidant support and helps promote visible radiance.
- Phytic Acid: Supports gentle exfoliation and a more even-looking complexion.
- Hibiscus Sabdariffa Flower Extract: Botanical extract included within the current brightening formula.
- Peach Leaf, Meadowsweet, Apple & Raspberry Extracts: Botanical ingredients incorporated into the current pigmentation-focused complex.
Full INCI List:
Water (Aqua), Glycerin, Niacinamide, Methylpropanediol, Sodium Gluconate, Lactic Acid, Maltodextrin, Sodium Lactate, Lactobacillus/Wasabia Japonica Root Ferment Extract, Magnesium Chloride, Mandelic Acid, Palmaria Palmata Extract, Prunus Persica (Peach) Leaf Extract, Spiraea Ulmaria Extract, Hibiscus Sabdariffa Flower Extract, Pyrus Malus (Apple) Fruit Extract, Rubus Idaeus (Raspberry) Fruit Extract, Phytic Acid, Citric Acid, Gluconolactone, Salicylic Acid, Ascorbic Acid, Sodium Salicylate, Vinegar (Acetum), Propylene Glycol, Magnesium Sulfate, Caprylyl Glycol, Sodium Hydroxide, Levulinic Acid, Sodium Levulinate, Sodium Benzoate, Potassium Sorbate, Sodium Bisulfite.
The lists of ingredients used in Biologique Recherche products are updated regularly. Before using a Biologique Recherche product, please refer to the ingredient list on its packaging.
If you have allergies or known ingredient sensitivities, please contact us at info@loshen.ca before purchasing. Our team will be happy to help verify the most current ingredient list for you.
Frequently Asked Questions
What is Biologique Recherche Lotion P50 PIGM 400?
Lotion P50 PIGM 400 is an exfoliating, brightening and anti-dark spot facial lotion from Biologique Recherche.
It is recommended specifically for dull-looking Skin Instants with uneven pigmentation.
What does Lotion P50 PIGM 400 do?
It combines chemical exfoliation with brightening and antioxidant ingredients to help reduce the visible appearance of dark spots, refine uneven texture and improve complexion radiance.
Is P50 PIGM 400 for hyperpigmentation?
Yes.
It is Biologique Recherche's Lotion P50 formula specifically positioned for uneven pigmentation and visible dark spots.
Does P50 PIGM 400 help dark spots?
Yes. Biologique Recherche specifically describes it as helping prevent and visibly diminish the appearance of pigmentation marks and dark spots.
Does P50 PIGM 400 help post-acne marks?
It can be particularly useful when previous blemishes have left behind visible pigmentation.
If redness, post-acne marks and skin restoration are also significant concerns, Iso-Placenta may provide complementary targeted support.
Does P50 PIGM 400 help sun spots?
Its current pigmentation-focused positioning makes it relevant to visible dark spots and uneven pigmentation.
Because UV exposure is one of the factors that can contribute to pigmentation, daily sun protection is particularly important in any routine focused on dark spots.
Does P50 PIGM 400 contain vitamin C?
Yes.
The current formula contains Ascorbic Acid, a form of Vitamin C, alongside Niacinamide and several exfoliating and botanical ingredients.
What acids are in P50 PIGM 400?
The current formula includes several exfoliating ingredients, including:
- Lactic Acid
- Mandelic Acid
- Gluconolactone
- Salicylic Acid
- Phytic Acid
- Citric Acid
This multi-acid approach is part of what differentiates Lotion P50 from a simple brightening toner.
Is P50 PIGM 400 good for dull skin?
Yes. Dull-looking skin is one of Biologique Recherche's primary current indications for Lotion P50 PIGM 400.
Can all skin tones use Lotion P50 PIGM 400?
The current Biologique Recherche recommendation is based on the Skin Instant and pigmentation concern, rather than the client's natural skin tone.
The goal is to improve uneven pigmentation and visible dark spots while preserving the individual's natural complexion.
Is P50 PIGM 400 good for beginners?
Biologique Recherche currently identifies Lotion P50 PIGM 400 as an ideal option for first-time Lotion P50 use when pigmentation and dullness are concerns.
We still recommend introducing it progressively according to the official first-week application method.
Why do I dilute P50 PIGM 400 during the first week?
The damp-cotton method provides a more progressive introduction to the exfoliating formula.
After the first week, Biologique Recherche recommends applying the lotion directly onto a dry cotton pad.
Should Lotion P50 PIGM 400 tingle?
Some clients may notice sensation when introducing an exfoliating lotion, but tingling is not the measure of whether the product is working.
Burning, persistent stinging, pronounced redness or discomfort should not simply be pushed through.
If your skin feels increasingly irritated, stop and contact our team so we can reassess your routine.
Can I use Lotion P50 PIGM 400 with retinol?
Biologique Recherche specifically states that Lotion P50 PIGM 400 should not be used during treatment with retinoic acid.
If you use prescription retinoids, retinol or another vitamin A treatment, contact our team so we can help determine an appropriate routine rather than layering active products without guidance.
Can I use P50 PIGM 400 around my eyes?
No.
Biologique Recherche specifically advises avoiding both the eyes and the eye contour area.
Can sensitive skin use P50 PIGM 400?
That depends on your current Skin Instant.
P50 PIGM 400 is an active multi-acid exfoliating formula. If the skin is fragile, reactive, scratched, irritated or experiencing barrier impairment, another approach may be more appropriate.
Do I need sunscreen when using P50 PIGM 400?
Yes, particularly when pigmentation is one of your concerns.
Biologique Recherche specifically advises avoiding immediate sun exposure after application, and daily sun protection is an essential part of maintaining the results of any pigmentation-focused routine.
What is the difference between Lotion P50 PIGM 400 and Sérum PIGM 400?
Lotion P50 PIGM 400 provides the exfoliating and preparation step.
Sérum PIGM 400 provides the more targeted pigmentation serum step.
The two may be combined within a personalized pigmentation-focused Biologique Recherche routine.
Is P50 PIGM 400 better than regular Lotion P50?
Not necessarily.
There is no universally “best” Lotion P50.
P50 PIGM 400 is the more targeted option when uneven pigmentation and dullness are central to the Skin Instant.
Other P50 formulas address different concerns.
Can I use P50 PIGM 400 every day?
Frequency should reflect your current Skin Instant and tolerance.
When first beginning, follow Biologique Recherche's progressive damp-cotton method for the first week rather than immediately increasing intensity.
When should I apply Lotion P50 PIGM 400?
Use after cleansing and before your Biologique Recherche serums and creams.
Allow the lotion to settle into the skin before continuing with the rest of your routine.
Where can I buy Biologique Recherche Lotion P50 PIGM 400?
Biologique Recherche Lotion P50 PIGM 400 is available from Loshen & Crem online and at our Edmonton, Alberta boutique.
Our skin experts can also help determine whether P50 PIGM 400 or another Lotion P50 formula is best suited to your current Skin Instant.
Biologique Recherche Skin Reaction Policy
At Loshen & Crem, we highly recommend completing a consultation with one of our skin experts before introducing a new Biologique Recherche product into your routine.
In the event of a skin reaction, Biologique Recherche may require:
- Clear photos of the reaction
- Photos of the product and lot number
- Proof of an online consultation with one of our skin experts
If you choose to purchase a Biologique Recherche product without a consultation and experience a reaction, we may be unable to provide a refund under the brand's policy.
If you are unsure whether Lotion P50 PIGM 400 is right for your Skin Instant, our team is always available to help.
Free Express Shipping with orders over $199
Available at our Edmonton Boutique
Ship to Canada only
Pickup available at Loshen & Crem
Usually ready in 24 hours

Lotion P50 PIGM 400
250 ml
Loshen & Crem
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
Returns & Refunds
At Loshen & Crem, we understand that sometimes, even the most carefully chosen product might not be "the one."
- Returns: You have 30 days from delivery to return any unopened and unused products in perfect condition—just as they arrived.
- Refunds: If your return reaches us within 30 days of purchase, you’ll have the choice between a refund or store credit (your preference, naturellement). After 30 days, store credit is your only option. Beyond 40 days, refunds and credits are no longer possible.
Final Sale Items
For transparency, certain items are final sale and not eligible for return or exchange:
- Products on sale
- Products marked “Final markdown” on our online store
- Gift cards
- Promotional kits and deluxe samples
- Limited-edition or seasonal item
Shipping Policy
At Loshen & Crem, we take delivering your skincare treasures très seriously. From Canada to the U.S., we’re here to ensure your beauty cabinet is always well-stocked.
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Free Shipping:
- Canada: Complimentary EXPRESS shipping on orders over $199 CAD (after discounts and before taxes).
- United States: Complimentary EXPRESS shipping on orders over $350 USD.
- During our annual sales, enjoy free EXPEDITED shipping for orders over $250 CAD (or $450 USD).
- For smaller indulgences, shipping is $27.95 CAD within Canada and $35 USD to the U.S.
P.S. We ship to P.O. Boxes via Canada Post—but not during strikes. C’est compliqué.
Processing Time:
We aim to dispatch your order within 2 business days, though peak sales and payment verifications may require a touch more patience.
Please note that if you make any changes with the courier after the dispatch, our carrier will charge a $32 fee. In addition, we will have to withdraw 800 points from your La Crème Points account. We appreciate your understanding.
Our processing time starts from the moment your order is successfully submitted and may take up to 2 business days to dispatch your order. However, please be aware that processing and handling time may be extended during peak sale periods. Before we can ship your order, we may need to hold your order for payment verification and confirm your details with your card issuer.
We will do our very best to minimize delays.
Shipping Rates & Delivery Times
Estimated Delivery Times (Canada):
- British Columbia & Alberta: 1–2 business days
- Manitoba & Saskatchewan: 1–2 business days
- Quebec & Ontario: 1–2 business days
- Atlantic Provinces: 1–3 business days
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United States: Delivery times vary by region:
- Zone 1: Eastern States – 3–4 business days
- Zone 2: Central States – 4–5 business days
- Zone 3: Western States – 5 business days
Remote areas may experience longer shipping times.Please Note: Shipping windows are estimates and not guarantees. Delays may occur due to weather, traffic, or additional verification processes.
Shipping Address Details
For a smooth delivery, please provide all relevant information, including buzzer codes, directional suffixes (North, South, etc.), or special instructions.
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Address Changes: Once your package has left our warehouse, address updates cannot be made. If you need to make changes before dispatch, email us at info@loshen.ca with your order details.
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Carrier Fees: Any changes made with the courier after dispatch will incur a $32 CAD fee, and the Free Express Shipping option will be deducted from your La Crème Points account.
Tracking Your Order
All shipments include tracking information, so you can follow your package from our warehouse to your door. A confirmation email with your tracking number will be sent once your order is dispatched.
Damaged or Lost Packages
- Damaged Parcels: If your order arrives damaged, please contact us at info@loshen.ca with photos and details. We’ll work to resolve the issue promptly.
- Lost or Stolen Packages: If your package is marked "delivered" but hasn’t arrived, please contact the carrier directly to file a claim.
Tips to Avoid Lost or Stolen Packages:
- Opt for a signature upon receipt (required for orders over $350 CAD).
- Have your package delivered to your workplace.
- If you’re not home on the expected delivery date, ask a neighbor to receive your package.
Unclaimed Parcels
If your package is returned to us unclaimed, we’ll issue a refund minus a $29.95 CAD return shipping fee.
Free Samples
We believe every order deserves a little extra care! Expect 1–3 complimentary samples selected by our Skincare Specialists to perfectly complement your order.
Loyalty Rewards: La Crem Points
Earn La Crème Points with every purchase and redeem them for future orders. From time to time, we also offer Free Gifts With Purchase (GWP) for select brands, but these are available only while supplies last.
At Loshen & Crem, we aim to deliver excellence at every step of your skincare journey, with care and a touch of elegance. Questions? Don’t hesitate to reach out—we’re always happy to assist!
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A final gesture of care, a whisper of radiance.
La Touche Finale
In this short video, discover how to apply your Biologique Recherche Finishing Serum, a precious step in your ritual that elevates your skin to its most refined state.
With just a few drops, pressed gently into the skin, your complexion is left silky, luminous, and perfectly sealed.






