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Lotion P50 PIGM 400

Sale price$160.00 CAD

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BRIGHTENING + ANTI-DARK SPOT EXFOLIATING LOTION

Biologique Recherche Lotion P50 PIGM 400 is an exfoliating and brightening facial lotion designed specifically for dull-looking Skin Instants with uneven pigmentation and visible dark spots.

It combines the exfoliating philosophy of the iconic Lotion P50 with brightening and antioxidant ingredients selected to support a more even-looking complexion.

By helping remove accumulated pigmented surface cells while supporting the skin against oxidative stress, Lotion P50 PIGM 400 helps visibly reduce the appearance of dark spots, refine uneven texture and restore luminosity.

With consistent use, the complexion appears smoother, brighter and more even.

Skin Instant:

Recommended for Skin Instants that appear dull with uneven pigmentation.

Particularly suited to skin experiencing:

  • Visible dark spots
  • Uneven-looking pigmentation
  • Post-blemish discoloration
  • Sun-associated pigmentation
  • A dull or lacklustre complexion
  • Uneven skin tone
  • Surface texture that appears less refined
  • A desire for gentle, progressive exfoliation alongside a pigmentation-focused routine

Biologique Recherche currently also identifies Lotion P50 PIGM 400 as an ideal option for those beginning with Lotion P50.

Benefits:
  • Gently exfoliates accumulated surface cells
  • Helps visibly reduce the appearance of dark spots
  • Supports a more even-looking complexion
  • Improves visible radiance and luminosity
  • Helps refine uneven skin texture
  • Provides antioxidant support
  • Helps limit oxidative stress associated with visible pigmentation
  • Purifies and refreshes the complexion
  • Helps prepare the skin for the targeted serums and creams that follow
Why Do Dark Spots Form?

Melanin is the pigment responsible for giving skin its colour.

Its production is a normal and essential biological process, but different factors can cause pigmentation to become uneven or more visible in certain areas.

These can include:

  • Sun exposure
  • Previous blemishes or inflammation
  • Hormonal influences
  • Repeated environmental stress
  • Changes that occur over time

The result may appear as:

  • Brown spots
  • Uneven patches
  • Post-blemish marks
  • A complexion that looks less uniform

Pigmentation is also rarely a surface-only concern.

This is why an effective routine generally needs to address both the visible accumulation of pigmented surface cells and the processes contributing to uneven pigmentation over time.

Lotion P50 PIGM 400 does this through a combination of exfoliating acids, brightening ingredients and antioxidant support.

How Does Lotion P50 PIGM 400 Work?

There are two important parts to its approach.

1. Exfoliation

Lotion P50 PIGM 400 contains several exfoliating acids, including:

  • Lactic Acid
  • Mandelic Acid
  • Gluconolactone
  • Salicylic Acid
  • Phytic Acid
  • Citric Acid

These help encourage the removal of accumulated surface cells so skin appears smoother, clearer and more refined.

2. Pigmentation + antioxidant support

Ingredients including Niacinamide, Wasabi Root Ferment, Palmaria Palmata Extract, Vitamin C and targeted botanical extracts help support a brighter, more uniform-looking complexion while limiting oxidative stress.

The result is not simply exfoliated skin.

The goal is progressively brighter, smoother and more even-looking skin.

Visible Results

In Biologique Recherche's current use evaluation:

  • 80% of participants reported a more purified complexion
  • 70% reported more beautiful, smoother and more exfoliated-looking skin
  • 65% noticed a more even-looking complexion
How to Use:

During the first week:

  1. Moisten a cotton pad with water, then apply Lotion P50 PIGM 400 to the damp cotton pad.
  2. Gently dab over the face, neck and décolleté using upward movements.

After the first week:

Apply Lotion P50 PIGM 400 directly onto a dry cotton pad and continue using gentle upward dabbing movements.

  • Do not rub or aggressively scrub the skin.
  • Avoid the eye contour area.
  • Do not use on scratched or irritated skin.
  • Do not use during treatment with retinoic acid.
  • Avoid direct sun exposure immediately after application.
  • Do not use on children under 3 years of age.
  • For external use only.
Loshen & Crem’s Recommendation:

P50 PIGM 400 is one of the Biologique Recherche lotions we reach for when a client tells us:

  • “My skin looks dull and uneven.”
  • “Every blemish leaves a dark mark behind.”
  • “I have brown spots that seem to become more noticeable over time.”
  • “I want P50, but pigmentation is one of my biggest concerns.”
  • “I want brighter skin, but I don't want to simply exfoliate more aggressively.”

That last one matters.

Pigmentation does not need to be attacked.

And more exfoliation does not automatically create a more even complexion.

We prefer P50 PIGM 400 because it combines controlled exfoliation + pigmentation-focused ingredients + antioxidant support within one step.

The goal isn't lighter skin.

The goal is your skin tone, more even.

Lotion P50 PIGM 400 vs. Other Lotion P50 Formulas

All Lotion P50 formulas belong to the same Biologique Recherche methodology, but they are selected according to different Skin Instants.

Choose Lotion P50 PIGM 400 when your primary concerns include:

  • Uneven pigmentation
  • Dark spots
  • Dullness
  • Post-blemish discoloration
  • A desire for brightening alongside exfoliation

Other Lotion P50 formulas may be more appropriate when the priority is instead:

  • Sebum and oiliness
  • Dehydration
  • Skin lacking tone
  • Other specific Skin Instant concerns

In the simplest terms:

P50 PIGM 400 = exfoliation + dark spots + radiance

If pigmentation is the reason you're reaching for P50, this is the formula we want to discuss first.

Lotion P50 PIGM 400 vs. Sérum PIGM 400

They belong beautifully within the same pigmentation-focused routine, but they do different jobs.

Lotion P50 PIGM 400 is the exfoliating preparation step.

It focuses on:

  • Surface-cell renewal
  • Exfoliation
  • Brightness
  • Uneven pigmentation
  • Preparing the epidermis for treatment

Sérum PIGM 400 is the targeted serum step.

It is designed more specifically around:

  • Visible pigmentation marks
  • Uneven tone
  • Brightening
  • Ongoing pigmentation-focused treatment

Think:

  • Lotion P50 PIGM 400 → exfoliate + prepare + brighten
  • Sérum PIGM 400 → targeted pigmentation treatment

For Skin Instants where pigmentation is a significant concern, the two can complement one another within a personalized routine.

Lotion P50 PIGM 400 vs. Iso-Placenta

This distinction becomes especially important when the dark mark appeared after a blemish.

Choose Lotion P50 PIGM 400 when your concerns are broader:

  • Uneven pigmentation
  • Brown spots
  • Dullness
  • Post-blemish discoloration
  • Surface texture

Choose Iso-Placenta when the bigger concern is:

  • The visible aftermath of blemishes
  • Post-acne marks
  • Redness left behind after inflammation
  • Uneven skin microrelief
  • Skin restoration

Think:

  • P50 PIGM 400 → pigmentation + exfoliation
  • Iso-Placenta → post-blemish restoration + marks

They may also complement one another when post-acne pigmentation and uneven texture occur together.

Is P50 PIGM 400 a Skin-Lightening Product?

We would not describe it that way.

Biologique Recherche describes P50 PIGM 400 as a brightening and anti-dark spot lotion designed to improve uneven pigmentation.

At Loshen & Crem, our goal is not to make someone's natural skin tone lighter.

The goal is to help reduce the visible contrast created by unwanted dark spots and uneven pigmentation so the complexion appears more uniform, luminous and balanced.

Ingredients:
  • Niacinamide: Vitamin B3 helps improve visible radiance and support a more even-looking complexion.
  • Lactic Acid: An alpha-hydroxy acid that helps exfoliate accumulated surface cells and refine texture.
  • Mandelic Acid: An AHA incorporated into the formula's progressive exfoliating complex.
  • Gluconolactone: A polyhydroxy acid that provides exfoliating and skin-conditioning support.
  • Salicylic Acid & Sodium Salicylate: Salicylates included within the purifying and exfoliating formula.
  • Lactobacillus/Wasabia Japonica Root Ferment Extract: Wasabi-derived ferment incorporated into the pigmentation-focused complex.
  • Palmaria Palmata Extract: A red algae-derived botanical ingredient included within the brightening formulation.
  • Ascorbic Acid: Vitamin C provides antioxidant support and helps promote visible radiance.
  • Phytic Acid: Supports gentle exfoliation and a more even-looking complexion.
  • Hibiscus Sabdariffa Flower Extract: Botanical extract included within the current brightening formula.
  • Peach Leaf, Meadowsweet, Apple & Raspberry Extracts: Botanical ingredients incorporated into the current pigmentation-focused complex.

Full INCI List:

Water (Aqua), Glycerin, Niacinamide, Methylpropanediol, Sodium Gluconate, Lactic Acid, Maltodextrin, Sodium Lactate, Lactobacillus/Wasabia Japonica Root Ferment Extract, Magnesium Chloride, Mandelic Acid, Palmaria Palmata Extract, Prunus Persica (Peach) Leaf Extract, Spiraea Ulmaria Extract, Hibiscus Sabdariffa Flower Extract, Pyrus Malus (Apple) Fruit Extract, Rubus Idaeus (Raspberry) Fruit Extract, Phytic Acid, Citric Acid, Gluconolactone, Salicylic Acid, Ascorbic Acid, Sodium Salicylate, Vinegar (Acetum), Propylene Glycol, Magnesium Sulfate, Caprylyl Glycol, Sodium Hydroxide, Levulinic Acid, Sodium Levulinate, Sodium Benzoate, Potassium Sorbate, Sodium Bisulfite.

The lists of ingredients used in Biologique Recherche products are updated regularly. Before using a Biologique Recherche product, please refer to the ingredient list on its packaging.

If you have allergies or known ingredient sensitivities, please contact us at info@loshen.ca before purchasing. Our team will be happy to help verify the most current ingredient list for you.

Frequently Asked Questions

What is Biologique Recherche Lotion P50 PIGM 400?

Lotion P50 PIGM 400 is an exfoliating, brightening and anti-dark spot facial lotion from Biologique Recherche.

It is recommended specifically for dull-looking Skin Instants with uneven pigmentation.

What does Lotion P50 PIGM 400 do?

It combines chemical exfoliation with brightening and antioxidant ingredients to help reduce the visible appearance of dark spots, refine uneven texture and improve complexion radiance.

Is P50 PIGM 400 for hyperpigmentation?

Yes.

It is Biologique Recherche's Lotion P50 formula specifically positioned for uneven pigmentation and visible dark spots.

Does P50 PIGM 400 help dark spots?

Yes. Biologique Recherche specifically describes it as helping prevent and visibly diminish the appearance of pigmentation marks and dark spots.

Does P50 PIGM 400 help post-acne marks?

It can be particularly useful when previous blemishes have left behind visible pigmentation.

If redness, post-acne marks and skin restoration are also significant concerns, Iso-Placenta may provide complementary targeted support.

Does P50 PIGM 400 help sun spots?

Its current pigmentation-focused positioning makes it relevant to visible dark spots and uneven pigmentation.

Because UV exposure is one of the factors that can contribute to pigmentation, daily sun protection is particularly important in any routine focused on dark spots.

Does P50 PIGM 400 contain vitamin C?

Yes.

The current formula contains Ascorbic Acid, a form of Vitamin C, alongside Niacinamide and several exfoliating and botanical ingredients.

What acids are in P50 PIGM 400?

The current formula includes several exfoliating ingredients, including:

  • Lactic Acid
  • Mandelic Acid
  • Gluconolactone
  • Salicylic Acid
  • Phytic Acid
  • Citric Acid

This multi-acid approach is part of what differentiates Lotion P50 from a simple brightening toner.

Is P50 PIGM 400 good for dull skin?

Yes. Dull-looking skin is one of Biologique Recherche's primary current indications for Lotion P50 PIGM 400.

Can all skin tones use Lotion P50 PIGM 400?

The current Biologique Recherche recommendation is based on the Skin Instant and pigmentation concern, rather than the client's natural skin tone.

The goal is to improve uneven pigmentation and visible dark spots while preserving the individual's natural complexion.

Is P50 PIGM 400 good for beginners?

Biologique Recherche currently identifies Lotion P50 PIGM 400 as an ideal option for first-time Lotion P50 use when pigmentation and dullness are concerns.

We still recommend introducing it progressively according to the official first-week application method.

Why do I dilute P50 PIGM 400 during the first week?

The damp-cotton method provides a more progressive introduction to the exfoliating formula.

After the first week, Biologique Recherche recommends applying the lotion directly onto a dry cotton pad.

Should Lotion P50 PIGM 400 tingle?

Some clients may notice sensation when introducing an exfoliating lotion, but tingling is not the measure of whether the product is working.

Burning, persistent stinging, pronounced redness or discomfort should not simply be pushed through.

If your skin feels increasingly irritated, stop and contact our team so we can reassess your routine.

Can I use Lotion P50 PIGM 400 with retinol?

Biologique Recherche specifically states that Lotion P50 PIGM 400 should not be used during treatment with retinoic acid.

If you use prescription retinoids, retinol or another vitamin A treatment, contact our team so we can help determine an appropriate routine rather than layering active products without guidance.

Can I use P50 PIGM 400 around my eyes?

No.

Biologique Recherche specifically advises avoiding both the eyes and the eye contour area.

Can sensitive skin use P50 PIGM 400?

That depends on your current Skin Instant.

P50 PIGM 400 is an active multi-acid exfoliating formula. If the skin is fragile, reactive, scratched, irritated or experiencing barrier impairment, another approach may be more appropriate.

Do I need sunscreen when using P50 PIGM 400?

Yes, particularly when pigmentation is one of your concerns.

Biologique Recherche specifically advises avoiding immediate sun exposure after application, and daily sun protection is an essential part of maintaining the results of any pigmentation-focused routine.

What is the difference between Lotion P50 PIGM 400 and Sérum PIGM 400?

Lotion P50 PIGM 400 provides the exfoliating and preparation step.

Sérum PIGM 400 provides the more targeted pigmentation serum step.

The two may be combined within a personalized pigmentation-focused Biologique Recherche routine.

Is P50 PIGM 400 better than regular Lotion P50?

Not necessarily.

There is no universally “best” Lotion P50.

P50 PIGM 400 is the more targeted option when uneven pigmentation and dullness are central to the Skin Instant.

Other P50 formulas address different concerns.

Can I use P50 PIGM 400 every day?

Frequency should reflect your current Skin Instant and tolerance.

When first beginning, follow Biologique Recherche's progressive damp-cotton method for the first week rather than immediately increasing intensity.

When should I apply Lotion P50 PIGM 400?

Use after cleansing and before your Biologique Recherche serums and creams.

Allow the lotion to settle into the skin before continuing with the rest of your routine.

Where can I buy Biologique Recherche Lotion P50 PIGM 400?

Biologique Recherche Lotion P50 PIGM 400 is available from Loshen & Crem online and at our Edmonton, Alberta boutique.

Our skin experts can also help determine whether P50 PIGM 400 or another Lotion P50 formula is best suited to your current Skin Instant.

Biologique Recherche Skin Reaction Policy

At Loshen & Crem, we highly recommend completing a consultation with one of our skin experts before introducing a new Biologique Recherche product into your routine.

In the event of a skin reaction, Biologique Recherche may require:

  • Clear photos of the reaction
  • Photos of the product and lot number
  • Proof of an online consultation with one of our skin experts

If you choose to purchase a Biologique Recherche product without a consultation and experience a reaction, we may be unable to provide a refund under the brand's policy.

If you are unsure whether Lotion P50 PIGM 400 is right for your Skin Instant, our team is always available to help.

Free Express Shipping with orders over $199

Available at our Edmonton Boutique

Ship to Canada only

In stock
Size:

Pickup available at Loshen & Crem

Usually ready in 24 hours

Biologique Recherche Lotion P50 PIGM 400 exfoliating lotion for dark spots and uneven pigmentation

Lotion P50 PIGM 400

250 ml

Loshen & Crem

Pickup available, usually ready in 24 hours

5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada

+17807229086
Biologique Recherche Lotion P50 PIGM 400 exfoliating lotion for dark spots and uneven pigmentation
Lotion P50 PIGM 400 Sale price$160.00 CAD

A final gesture of care, a whisper of radiance.

La Touche Finale

In this short video, discover how to apply your Biologique Recherche Finishing Serum, a precious step in your ritual that elevates your skin to its most refined state.

With just a few drops, pressed gently into the skin, your complexion is left silky, luminous, and perfectly sealed.

  • 5 stars: 102 (96%)
  • 4 stars: 4 (4%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
S
Saghar
My favourite exfoliant

P50 PIGM 400 is very gentle on my skin but gives it a nice smooth deep glowing look.

M
Munir

Amazing shop to order feom. Arrived the next day with a thank you note. Will be my go-to shop for cosmetics from now on. Thanks so much!

K
Kate
Gentle

Very gentle exfoliating lotion. Did not irritate my skin.

A
Am
believer

i cant be without it. sadly last one expired as i didnt end using it as much and decided prob best to just keep getting small size. thankful that it comes in a smaller size!

I
Iryna

Lotion P50 PIGM 400 really helps to lighten pigmentation and even out skin tone. After a few weeks, the skin looks brighter, smoother, and more radiant. If you use it with a damp cotton pad for the first two weeks, it prevents irritation and lets the skin get used to the active acids gradually. I love the refreshed and glowing look it gives! 💫

J
Juliana
3+years in..still my #1 for brighter,clearer skin.

After 3+ years, I can confidently say this is a holy grail product. If you’re dealing with dullness, scarring, or texture issues, and want results without harsh acids, P50 PIGM 400 is worth every drop.

C
Catherine
Holy grail

I’ve used this daily for almost 5 years now and it has changed the texture of my skin. I will never be without!

B
BR
Holy grail for ten years!

The best for hyperpigmentation and glow! The best version of P50 for me. Loshen’s team is also amazing as always!

L
Lily
Still the best

I have tried other brands of toner and none is as effective as this one! I can see an obvious results with just a few days of using!

M
Madeline

Amazing product, and delivery was so fast. They even wrote me a personalized note to thank me for my order! Will definitely order from them again and have already recommended them to my coworkers.

P
Patricia
So far so good

Been using it in the evening. Skin is glowy however looking forward to more results as time goes on

K
Kr
HAD a purging period on my chin area

But oh my god. the minute it ended my skin GLOWY no texture healthy looking pigmentation gone. I AM OBSESSED !!!!!!!!!!! worth every penny

J
Jennifer

In

S
Samantha
P50 PIGM— chef’s kiss!

Best toner I’ve ever had. I will keep repurchasing.
It’s evened out my texture and I can see improvement in my hyperpigmentation since using it. Skin looks so much more radiant.
Love it.

P
Palakka678@gmail.com

LOTION P50 PIGM 400

E
Ellie
Very brightening yet gentle

I love this! Very gentle and it instantly brightens my skin. The only complaint i have is that is is a but sticky to leave on.

E
E.J.
Gentle enough for frequent use

By far the gentlest version of P50 I have tried. Brightens well but less exfoliating power

D
Devora
Perfect

Great product and fast shipping !

T
T.K.
Love this version

I feel like it smells different compared to the standard version. There is a strong smell. But this one feels more mild on the skin! I don’t use it on cheeks prone to rosacea though so if you have rosacea- consult

H
Holly
Instant effect

The brightening effect is immediate. Not irritating.

Y
Yelena
love this lotion

This lotion by far is the best one I have ever tried. It keeps my skin clean, plumped and adds nice glowing tone. I recommend everyone to give it a try.

Y
Yelena
The best lotion

This lotion by far is the best one I have ever tried. It keeps my skin clean, plumped and adds nice glowing tone. I recommend everyone to give it a try.

k
kayla
An essential

Sometimes will take for granted and put to the side in my routine, but every time I phase it back in I realize how great of a difference it does make to my skin texture

V
Virginie
Je préfère à la version originale

Cette version de la lotion de biologique recherche m'est apparue plus douce que l'orginale : ma peau était moins rouge. De plus, l'odeur était moins forte.

M
Margarita
A staple product

This is a staple in my skin routine, I do sometimes give my skin a break from it but love it so much more when I get back to it.

D
Diana
BR Lotion P50 PIGM 400

So far, so good, after using this product for 2 weeks. Skin is smooth and the product has replaced my other exfoliants for now. Can’t say that I’ve seen a difference in post-inflammatory pigmentation yet, but we shall see with continued use.

B
Bella
Can't live without it

I've used P50 for almost 10 years now. I recently ran out and for the first time ever, I gave my skin a short (2 weeks) break from P50 Pigm 400 and I realized I can't live without it. I know it's good to give your skin a break every now and then, but this is such a game changer for my skin care routine. I don't think I'll ever take a break that long again.

M
M.D.
P50 magic

I love P50. It was gamechanging when I first tried it. I take breaks from it sometimes because I seem to get immune to it. But I always come back to it to help keep me skin clear, exfoliated and bright.

K
Kelly
Pigm50

Great product, super fast shipping. I will reorder from your company again!

M
Miriam
A Must Have

I love this product.
It brightens my skin. It helps with hyperpigmentation and age spots and smoothness of my skin. My favorite of the 2. Highly recommend.

C
Carmeline
Holy Grail

I've been using Lotion Pigm 400 for years now and it's my holy grail product. It has made so much difference to my facial skin texture and pimple scars (I get dark pimple scars).

M
Marie-Christine
Very good!

Love this product! Helps so much with my hyperpigmentation.