

Complexe Iribiol
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REBALANCING + PURIFYING SERUM
Biologique Recherche Complexe Iribiol is a targeted rebalancing serum designed for seborrheic and blemish-prone Skin Instants experiencing excess sebum, visible pores and recurring imperfections.
Its concentrated formula combines Zinc PCA, Salicylic Acid, Iris Root Extract and Red Poppy Extract to help regulate excess sebum while refining the appearance of dilated pores and uneven skin texture.
With consistent use, skin appears less oily, pores look less noticeable and the complexion feels clearer and more balanced.
Complexe Iribiol is particularly valuable when the concern is not simply an occasional blemish, but a pattern of excess oil + visible pores + recurring imperfections.
Skin Instant:
Recommended for seborrheic and blemish-prone Skin Instants.
Particularly suited to skin experiencing:
- Excess sebum
- Persistent oiliness or shine
- Recurring blemishes
- Visible or enlarged-looking pores
- Congestion
- Uneven skin texture
- A T-zone that becomes oily quickly
- Skin that feels difficult to keep balanced
Benefits:
- Helps regulate excess sebum
- Visibly reduces oiliness and shine
- Helps refine the appearance of enlarged pores
- Improves the look of uneven skin texture
- Helps reduce the appearance of skin imperfections
- Supports clearer, more balanced-looking skin
- Provides a mattifying effect
- Helps refine seborrheic and blemish-prone Skin Instants
Why Does Excess Sebum Affect Pores and Breakouts?
Sebum is not the enemy.
It is a natural mixture of lipids produced by the sebaceous glands and plays an important role in protecting and lubricating the skin.
The concern begins when too much sebum is produced.
Excess sebum can accumulate within the pores and contribute to:
- More visible pores
- Congestion
- Increased shine
- Uneven-looking texture
- An environment where imperfections may develop more easily
This is why simply trying to “dry out” oily skin is rarely the best strategy.
Complexe Iribiol is designed around regulation and balance, helping reduce excess oil while refining the visible appearance of pores and imperfections.
How to Use:
- Apply approximately 1 ml (20 drops) of Complexe Iribiol to clean skin over the face, neck and décolleté.
- Massage gently using light upward movements until completely absorbed.
- Within a Biologique Recherche routine, apply after cleansing and your appropriate Lotion P50 and before your moisturizer.
- Pay particular attention to areas where excess sebum and visible pores are most noticeable.
Avoid contact with the eyes. For external use only. Do not use on children under 3 years of age.
Loshen & Crem’s Recommendation:
Complexe Iribiol is one of the Biologique Recherche serums we reach for when someone tells us:
- “My skin gets oily again a few hours after cleansing.”
- “I constantly get little breakouts in the same areas.”
- “My pores look much larger when my skin gets oily.”
- “My T-zone never seems balanced.”
- “I need something for the breakouts I have now, not only the marks they leave behind.”
That last one is key.
Complexe Iribiol and Iso-Placenta are often discussed together, but they have very different jobs.
We think of Complexe Iribiol during the active blemish and excess-sebum stage.
Once the blemish has settled and the concern becomes the red or dark mark it left behind, our strategy often changes.
That is why Complexe Iribiol can be such an important part of a blemish-prone routine — but it doesn't need to do every job.
Complexe Iribiol vs. Iso-Placenta
This is probably the most important comparison for blemish-prone Skin Instants.
Choose Complexe Iribiol when your primary concerns are:
- Active or recurring blemishes
- Excess sebum
- Oiliness
- Congestion
- Enlarged-looking pores
- A seborrheic Skin Instant
Choose Iso-Placenta when the blemish has resolved and your primary concerns are:
- Post-blemish marks
- Redness left after imperfections
- Uneven skin microrelief
- Visible traces of previous breakouts
- Skin restoration
In the simplest terms:
- Complexe Iribiol = active blemishes + excess sebum
- Iso-Placenta = post-blemish marks + skin restoration
The two may sometimes exist within the same personalized routine because active blemishes and previous blemish marks often occur at the same time.
Complexe Iribiol vs. Sérum Dermopore
Both are sebum-regulating Biologique Recherche serums, but the priority is different.
Choose Complexe Iribiol when the main concerns include:
- Recurring blemishes
- Excess sebum
- Congestion
- Oiliness
- Visible pores alongside imperfections
Choose Sérum Dermopore when the main concern is more specifically:
- Enlarged or highly visible pores
- Excess shine
- Uneven texture
- Sebum imbalance without significant active blemishes
Think:
- Complexe Iribiol → blemishes + sebum + pores
- Dermopore → visible pores + shine + texture
If your pores bother you more than your blemishes, Dermopore may be the more targeted choice.
If active imperfections are part of the picture, Complexe Iribiol usually makes more sense.
Complexe Iribiol vs. Crème Dermopurifiante
These products are complementary rather than interchangeable.
Complexe Iribiol is the targeted serum step focused on:
- Excess sebum
- Visible pores
- Skin imperfections
- Seborrheic imbalance
Crème Dermopurifiante is the moisturizing treatment step within a routine designed for imbalanced and blemish-prone Skin Instants.
Think:
- Complexe Iribiol → targeted rebalancing serum
- Crème Dermopurifiante → purifying + balancing moisturizer
Depending on your Skin Instant, they may work beautifully together.
Ingredients:
- Zinc PCA: Helps regulate excess sebum and supports a more balanced-looking complexion.
- Salicylic Acid: A beta-hydroxy acid that helps refine the appearance of pores and uneven skin texture.
- Iris Florentina Root Extract: A botanical extract incorporated into Complexe Iribiol's targeted rebalancing formula.
- Papaver Rhoeas Petal Extract: Red poppy extract included within the serum's skin-conditioning complex.
- Propylene Glycol: Helps support hydration and ingredient delivery within the lightweight formula.
Full INCI List:
Water (Aqua), Alcohol Denat., Propylene Glycol, Zinc PCA, Salicylic Acid, Papaver Rhoeas Petal Extract, Iris Florentina Root Extract.
The lists of ingredients used in Biologique Recherche products are updated regularly. Before using a Biologique Recherche product, please refer to the ingredient list on its packaging.
If you have allergies or known ingredient sensitivities, please contact us at info@loshen.ca before purchasing. Our team will be happy to help verify the most current ingredient list for you.
Frequently Asked Questions
What is Biologique Recherche Complexe Iribiol?
Complexe Iribiol is a rebalancing, purifying and sebum-regulating facial serum from Biologique Recherche specifically recommended for seborrheic and blemish-prone Skin Instants.
It helps regulate excess sebum while reducing the appearance of enlarged pores and uneven skin texture.
Is Complexe Iribiol good for blemish-prone skin?
Yes. Biologique Recherche specifically recommends Complexe Iribiol for Skin Instants prone to seborrhea and acne.
We prefer to describe it as a targeted serum for blemish-prone Skin Instants rather than promising that a cosmetic serum can treat every form or cause of acne.
Does Complexe Iribiol contain salicylic acid?
Yes. Salicylic Acid is one of the seven ingredients in the current Complexe Iribiol formula.
It is combined with Zinc PCA, Iris Florentina Root Extract and Red Poppy Extract within the serum's targeted rebalancing formula.
Does Complexe Iribiol reduce pores?
Complexe Iribiol helps visibly reduce the appearance of dilated pores.
Pores cannot permanently “open” or “close,” but regulating excess sebum and improving surface texture can make them appear less noticeable.
Does Complexe Iribiol help oily skin?
Yes. Sebum regulation is one of its primary current indications.
Biologique Recherche specifically describes the skin as becoming visibly less oily with continued use.
Does Complexe Iribiol help blackheads and congestion?
Because excess sebum and pore congestion are closely connected, Complexe Iribiol can be relevant when congestion occurs alongside a seborrheic Skin Instant.
Your overall routine still matters, particularly your cleanser, Lotion P50 and moisturizer.
Does Complexe Iribiol help acne scars or post-acne marks?
Post-acne marks and active blemishes require different approaches.
Complexe Iribiol is primarily designed for excess sebum, blemish-prone skin and visible pores.
If the blemish has resolved and the main concern is the red or dark mark left behind, Iso-Placenta is usually the more targeted Biologique Recherche conversation.
True structural acne scars are also different from post-blemish marks and cannot simply be erased with a topical serum.
What is the difference between Complexe Iribiol and Iso-Placenta?
Complexe Iribiol focuses on active blemish-prone, seborrheic skin and excess sebum.
Iso-Placenta focuses on post-acne marks, redness, uneven skin microrelief and skin restoration after blemishes.
What is the difference between Complexe Iribiol and Dermopore?
Both help regulate sebum and improve visible pores.
Complexe Iribiol is more specifically suited when blemishes and seborrhea are part of the concern.
Dermopore is more specifically focused on dilated pores, excess shine and uneven texture.
Can I use Complexe Iribiol as a spot treatment?
Biologique Recherche's current official instructions recommend applying approximately 1 ml over the face, neck and décolleté.
Depending on your Skin Instant, your skin expert may recommend concentrating application in areas where excess sebum or imperfections are more noticeable.
Can Complexe Iribiol dry out my skin?
Complexe Iribiol contains Alcohol Denat. and Salicylic Acid, and some Skin Instants may experience increased dryness or tightness if the product is used too aggressively or combined with too many exfoliating products.
If your skin begins to feel tight or uncomfortable, we recommend having your routine reassessed rather than simply adding more active products.
Can sensitive skin use Complexe Iribiol?
It depends on the Skin Instant.
Because the formula contains Alcohol Denat. and Salicylic Acid, highly reactive or compromised skin may require a different approach.
If sensitivity is part of your concern, we recommend speaking with one of our skin experts before introducing it.
Can I use Complexe Iribiol with Lotion P50?
Yes, when appropriate for your Skin Instant.
Because both products can be active, the specific Lotion P50 version and frequency of use should be personalized rather than assuming stronger is always better.
Can I use Complexe Iribiol every day?
It may be incorporated into a daily routine depending on your Skin Instant and the rest of your regimen.
Biologique Recherche currently instructs users to apply 1 ml to cleansed skin but does not specify that every client must use it twice daily.
When should I apply Complexe Iribiol?
Apply after cleansing and your appropriate Lotion P50 and before your moisturizer.
When layering multiple serums, apply your lighter formulas first.
Who should use Biologique Recherche Complexe Iribiol?
It is particularly suited to seborrheic and blemish-prone Skin Instants experiencing excess oil, recurring imperfections and visible pores.
Where can I buy Biologique Recherche Complexe Iribiol?
Biologique Recherche Complexe Iribiol is available from Loshen & Crem online and at our Edmonton, Alberta boutique.
Our skin experts can also help determine whether Complexe Iribiol, Iso-Placenta, Dermopore or another Biologique Recherche treatment is best suited to your current Skin Instant.
Biologique Recherche Skin Reaction Policy
At Loshen & Crem, we highly recommend completing a consultation with one of our skin experts before introducing a new Biologique Recherche product into your routine.
In the event of a skin reaction, Biologique Recherche may require:
- Clear photos of the reaction
- Photos of the product and lot number
- Proof of an online consultation with one of our skin experts
If you choose to purchase a Biologique Recherche product without a consultation and experience a reaction, we may be unable to provide a refund under the brand's policy.
If you are unsure whether Complexe Iribiol is right for your Skin Instant, our team is always available to help.
Free Express Shipping with orders over $199
Available at our Edmonton Boutique
Ship to Canada only
Pickup available at Loshen & Crem
Usually ready in 24 hours

Complexe Iribiol
30 ml
Loshen & Crem
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
Returns & Refunds
At Loshen & Crem, we understand that sometimes, even the most carefully chosen product might not be "the one."
- Returns: You have 30 days from delivery to return any unopened and unused products in perfect condition—just as they arrived.
- Refunds: If your return reaches us within 30 days of purchase, you’ll have the choice between a refund or store credit (your preference, naturellement). After 30 days, store credit is your only option. Beyond 40 days, refunds and credits are no longer possible.
Final Sale Items
For transparency, certain items are final sale and not eligible for return or exchange:
- Products on sale
- Products marked “Final markdown” on our online store
- Gift cards
- Promotional kits and deluxe samples
- Limited-edition or seasonal item
Shipping Policy
At Loshen & Crem, we take delivering your skincare treasures très seriously. From Canada to the U.S., we’re here to ensure your beauty cabinet is always well-stocked.
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Free Shipping:
- Canada: Complimentary EXPRESS shipping on orders over $199 CAD (after discounts and before taxes).
- United States: Complimentary EXPRESS shipping on orders over $350 USD.
- During our annual sales, enjoy free EXPEDITED shipping for orders over $250 CAD (or $450 USD).
- For smaller indulgences, shipping is $27.95 CAD within Canada and $35 USD to the U.S.
P.S. We ship to P.O. Boxes via Canada Post—but not during strikes. C’est compliqué.
Processing Time:
We aim to dispatch your order within 2 business days, though peak sales and payment verifications may require a touch more patience.
Please note that if you make any changes with the courier after the dispatch, our carrier will charge a $32 fee. In addition, we will have to withdraw 800 points from your La Crème Points account. We appreciate your understanding.
Our processing time starts from the moment your order is successfully submitted and may take up to 2 business days to dispatch your order. However, please be aware that processing and handling time may be extended during peak sale periods. Before we can ship your order, we may need to hold your order for payment verification and confirm your details with your card issuer.
We will do our very best to minimize delays.
Shipping Rates & Delivery Times
Estimated Delivery Times (Canada):
- British Columbia & Alberta: 1–2 business days
- Manitoba & Saskatchewan: 1–2 business days
- Quebec & Ontario: 1–2 business days
- Atlantic Provinces: 1–3 business days
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United States: Delivery times vary by region:
- Zone 1: Eastern States – 3–4 business days
- Zone 2: Central States – 4–5 business days
- Zone 3: Western States – 5 business days
Remote areas may experience longer shipping times.Please Note: Shipping windows are estimates and not guarantees. Delays may occur due to weather, traffic, or additional verification processes.
Shipping Address Details
For a smooth delivery, please provide all relevant information, including buzzer codes, directional suffixes (North, South, etc.), or special instructions.
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Address Changes: Once your package has left our warehouse, address updates cannot be made. If you need to make changes before dispatch, email us at info@loshen.ca with your order details.
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Carrier Fees: Any changes made with the courier after dispatch will incur a $32 CAD fee, and the Free Express Shipping option will be deducted from your La Crème Points account.
Tracking Your Order
All shipments include tracking information, so you can follow your package from our warehouse to your door. A confirmation email with your tracking number will be sent once your order is dispatched.
Damaged or Lost Packages
- Damaged Parcels: If your order arrives damaged, please contact us at info@loshen.ca with photos and details. We’ll work to resolve the issue promptly.
- Lost or Stolen Packages: If your package is marked "delivered" but hasn’t arrived, please contact the carrier directly to file a claim.
Tips to Avoid Lost or Stolen Packages:
- Opt for a signature upon receipt (required for orders over $350 CAD).
- Have your package delivered to your workplace.
- If you’re not home on the expected delivery date, ask a neighbor to receive your package.
Unclaimed Parcels
If your package is returned to us unclaimed, we’ll issue a refund minus a $29.95 CAD return shipping fee.
Free Samples
We believe every order deserves a little extra care! Expect 1–3 complimentary samples selected by our Skincare Specialists to perfectly complement your order.
Loyalty Rewards: La Crem Points
Earn La Crème Points with every purchase and redeem them for future orders. From time to time, we also offer Free Gifts With Purchase (GWP) for select brands, but these are available only while supplies last.
At Loshen & Crem, we aim to deliver excellence at every step of your skincare journey, with care and a touch of elegance. Questions? Don’t hesitate to reach out—we’re always happy to assist!
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A final gesture of care, a whisper of radiance.
La Touche Finale
In this short video, discover how to apply your Biologique Recherche Finishing Serum, a precious step in your ritual that elevates your skin to its most refined state.
With just a few drops, pressed gently into the skin, your complexion is left silky, luminous, and perfectly sealed.






