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AveneAvène Tolérance Extremely Gentle Cleanser
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To cleanse without stripping
ASCEplus ExoBalm Plant-Derived Mixing Balm
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Explore La Crem rewardsA two-phase balm with rose-derived exosomes to comfort, replenish and calm sensitized-looking skin
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ASCEplus
ExoBalm Plant-Derived Mixing Balm
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$280.00 CAD
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The skincare focus
ASCEplus ExoBalm Plant-Derived Mixing Balm
A two-phase balm with rose-derived exosomes to comfort, replenish and calm sensitized-looking skin
Explore our ingredient glossaryASCEplus
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Rose-derived exosomes
Extracellular vesicles isolated from cultured Damask rose cells, kept freeze-dried until you activate the kit. Plant-derived, they help condition and comfort the skin.
Niacinamide and tranexamic acid
Two well-studied actives in the balm phase that help soften the look of redness and uneven tone while supporting the barrier.
Madecassoside and panthenol
Madecassoside, from centella asiatica, joins panthenol and allantoin to soothe skin that feels tight or reactive.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Your routine
BiophoraAdvanced Protection SPF 45
Why it fits
Biophora’s water- and sweat-resistant broad-spectrum SPF 45, for active days, sports and summer outdoors. Every morning, as the last step.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
ASCEplus ExoBalm Plant-Derived Mixing Balm
A two-phase balm with rose-derived exosomes to comfort, replenish and calm sensitized-looking skin
ASCEplus ExoBalm Plant-Derived Mixing Balm is a fresh-mix comfort treatment from ExoCoBio, the Korean biotech company behind ExoSCRT® exosome purification technology. It arrives in two parts: a 20 mg freeze-dried EXO Capsule containing rose-derived exosomes, peptides, amino acids and vitamins, and a 20 mL W-Formula nourishing balm. The two are combined just before first use, so the capsule's actives stay stable until the moment you need them.
Once mixed, the balm pairs these rose-derived extracellular vesicles with niacinamide, tranexamic acid, madecassoside, panthenol, ceramide NP and cholesterol to support the moisture barrier, soften the look of redness and leave skin feeling calm, supple and comfortable.
It is the balm we reach for when skin feels stressed, depleted or more reactive than usual, including the days following a professional skin treatment when your esthetician recommends it.
Benefits
- Comforts skin that feels sensitized, tight or reactive
- Reinforces the moisture barrier with ceramide NP, cholesterol and squalane
- Helps soften the appearance of redness and uneven tone
- Provides intensive, lasting hydration
- Supports a smoother, more resilient-looking complexion
- Leaves skin feeling soft and nourished without a heavy finish
How to use
- Activate once: Before first use, add the EXO Capsule to the W-Formula balm and mix with the enclosed spatula. Keep refrigerated (4–8°C) from then on.
- Cleanse gently: Use a non-foaming cleanser and pat the skin dry. A hydrating mist is welcome.
- Apply the balm: Smooth a thin, even layer over clean, dry skin as your moisturizing step.
- Protect by day: In the morning, finish with broad-spectrum sunscreen.
Precautions
Full Ingredient List
Capsule Phase – INCI:
Water (Aqua), Sodium Hyaluronate, Methionine, Trehalose, Rosa Damascena Callus Extracellular Vesicles, Potassium Chloride, Ascorbic Acid, Magnesium Sulfate, Mannitol, Lysine, Tryptophan, Glutathione, Histidine, Rosa Damascena Flower Water, Glutamic Acid, Serine, 1,2-Hexanediol, Butylene Glycol, Nicotinamide Adenine Dinucleotide, Biotin, Maltodextrin, Coenzyme A, Sodium Citrate, Acetyl Hexapeptide-8, Nonapeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Disodium Flavine Adenine Dinucleotide, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Citric Acid, Cyanocobalamin
Balm Phase – INCI:
Caprylic/Capric Triglyceride, Glycerin, Squalane, Niacinamide, Tranexamic Acid, Helianthus Annuus Seed Oil, Arachidyl Alcohol, Dipropylene Glycol, Dimethicone, Butyrospermum Parkii Butter, Beeswax, Behenyl Alcohol, Cetearyl Alcohol, Carbomer, Arachidyl Glucoside, Palmitic Acid, Stearic Acid, Tocopheryl Acetate, Allantoin, Panthenol, Ethylhexylglycerin, Caprylyl Glycol, Pentylene Glycol, Sodium Hyaluronate, Adenosine, Disodium EDTA, Hydrogenated Lecithin, Cholesterol, Ceramide NP, Glucose, Hydroxyphenyl Propamidobenzoic Acid, Arachidic Acid, Madecassoside, 3-O-Ethyl Ascorbic Acid, Lauric Acid
Ingredient lists may change. Always refer to the product packaging for the most current ingredient list, particularly if you have allergies or sensitivities. Contact info@loshen.ca if you need help reviewing the formula before purchasing.
Shipping & returns
For delivery and return information, view our policy.
A two-phase balm with rose-derived exosomes to comfort, replenish and calm sensitized-looking skin
ASCEplus ExoBalm Plant-Derived Mixing Balm is a fresh-mix comfort treatment from ExoCoBio, the Korean biotech company behind ExoSCRT® exosome purification technology. It arrives in two parts: a 20 mg freeze-dried EXO Capsule containing rose-derived exosomes, peptides, amino acids and vitamins, and a 20 mL W-Formula nourishing balm. The two are combined just before first use, so the capsule's actives stay stable until the moment you need them.
Once mixed, the balm pairs these rose-derived extracellular vesicles with niacinamide, tranexamic acid, madecassoside, panthenol, ceramide NP and cholesterol to support the moisture barrier, soften the look of redness and leave skin feeling calm, supple and comfortable.
It is the balm we reach for when skin feels stressed, depleted or more reactive than usual, including the days following a professional skin treatment when your esthetician recommends it.
Benefits
- Comforts skin that feels sensitized, tight or reactive
- Reinforces the moisture barrier with ceramide NP, cholesterol and squalane
- Helps soften the appearance of redness and uneven tone
- Provides intensive, lasting hydration
- Supports a smoother, more resilient-looking complexion
- Leaves skin feeling soft and nourished without a heavy finish
Best For
- Sensitive, reactive or intolerant-feeling skin
- Skin that looks red, dry or depleted
- Skin that feels fragile or thin
- Comfort care after professional treatments, when recommended by your esthetician
- Anyone who wants barrier support with a modern, fresh-mix format
The balm contains beeswax and shea butter. It is not vegan.
Why It Is Different
Most "exosome" skincare uses plant juices or extracts marketed under the exosome name. ExoBalm's capsule contains extracellular vesicles isolated from cultured Damask rose cells (listed on the label as Rosa Damascena Callus Extracellular Vesicles) and kept freeze-dried until you activate the kit.
- Rose-Derived Exosomes (Rosa Damascena Callus Extracellular Vesicles): Plant-derived vesicles that help condition and comfort the skin.
- Peptide Complex: Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Acetyl Hexapeptide-8 and Nonapeptide-1 support a smoother, more even-looking complexion.
- Niacinamide and Tranexamic Acid: Help soften the look of redness and uneven tone.
- Madecassoside, Panthenol and Allantoin: Soothe and comfort.
- Ceramide NP, Cholesterol and Squalane: Replenish the lipids of the skin barrier.
- Glutathione, Vitamin C and Vitamin B12: Provide antioxidant support.
How to Use
Before first use, add the EXO Capsule to the W-Formula balm and mix with the enclosed spatula until fully combined. Once mixed, keep the balm in the refrigerator (4–8°C) and use it within 21 days.
Apply a thin, even layer to clean, dry skin as the moisturizing step of your routine, or as directed by your esthetician after a professional treatment. During the day, finish with broad-spectrum sunscreen.
Loshen & Crem’s Recommendation
We like ExoBalm for clients whose skin is simply overwhelmed: too many actives, a change of season, a busy stretch of treatments. Keep the rest of the routine simple while you use it: a gentle non-foaming cleanser, a hydrating mist, ExoBalm, and sunscreen in the morning.
Because it is mixed fresh and must be used within 21 days once activated, plan to use it morning and evening rather than occasionally. If you are unsure whether it suits your skin, book a consultation with our team in Edmonton or virtually.
Understanding "Exosomes" in Skincare
Exosomes are tiny vesicles cells use to carry signals. In ExoBalm they are plant-derived, isolated from cultured rose cells. They are not human-derived and contain no living cells.
In a cosmetic, they are used to condition and comfort the skin and support its appearance. They are not a medical treatment and do not replace the aftercare instructions your professional gives you.
Ingredients
Capsule Phase – INCI:
Water (Aqua), Sodium Hyaluronate, Methionine, Trehalose, Rosa Damascena Callus Extracellular Vesicles, Potassium Chloride, Ascorbic Acid, Magnesium Sulfate, Mannitol, Lysine, Tryptophan, Glutathione, Histidine, Rosa Damascena Flower Water, Glutamic Acid, Serine, 1,2-Hexanediol, Butylene Glycol, Nicotinamide Adenine Dinucleotide, Biotin, Maltodextrin, Coenzyme A, Sodium Citrate, Acetyl Hexapeptide-8, Nonapeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Disodium Flavine Adenine Dinucleotide, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Citric Acid, Cyanocobalamin
Balm Phase – INCI:
Caprylic/Capric Triglyceride, Glycerin, Squalane, Niacinamide, Tranexamic Acid, Helianthus Annuus Seed Oil, Arachidyl Alcohol, Dipropylene Glycol, Dimethicone, Butyrospermum Parkii Butter, Beeswax, Behenyl Alcohol, Cetearyl Alcohol, Carbomer, Arachidyl Glucoside, Palmitic Acid, Stearic Acid, Tocopheryl Acetate, Allantoin, Panthenol, Ethylhexylglycerin, Caprylyl Glycol, Pentylene Glycol, Sodium Hyaluronate, Adenosine, Disodium EDTA, Hydrogenated Lecithin, Cholesterol, Ceramide NP, Glucose, Hydroxyphenyl Propamidobenzoic Acid, Arachidic Acid, Madecassoside, 3-O-Ethyl Ascorbic Acid, Lauric Acid
Ingredient lists may change. Always refer to the product packaging for the most current ingredient list, particularly if you have allergies or sensitivities. Contact info@loshen.ca if you need help reviewing the formula before purchasing.
Frequently Asked Questions
What is ASCEplus ExoBalm?
A two-phase comfort balm: a 20 mg freeze-dried EXO Capsule of rose-derived exosomes, peptides and vitamins that you mix into a 20 mL barrier-supporting W-Formula balm before first use.
Why does it need to be mixed?
Keeping the capsule freeze-dried protects its delicate actives until activation. Once mixed, the balm is fresh: keep it refrigerated (4–8°C) and use it within 21 days.
Are the exosomes human-derived?
No. They are plant-derived, from cultured Damask rose cells.
Is it suitable for sensitive or redness-prone skin?
It was designed for sensitized-looking skin and contains soothing and barrier-supporting ingredients. As with any new product, highly reactive skin should patch test first.
Can I use it after a professional treatment?
Only when recommended by the professional who performed your treatment, and always alongside their aftercare instructions.
Is it fragrance-free?
No added fragrance is listed. The capsule contains rose flower water.
Is it vegan?
No. The balm contains beeswax.
Does it contain retinol or exfoliating acids?
No retinoid or exfoliating AHA/BHA is listed. Citric acid appears in small amounts to adjust pH.
Can it be used during pregnancy or breastfeeding?
The balm contains tranexamic acid. Complete pregnancy safety data are not available for every finished cosmetic, so consult your healthcare provider first.
Does it provide sun protection?
No. Apply a broad-spectrum sunscreen every morning.
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your order01 · Across Canada
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Collect in Edmonton.
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Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Rose-derived exosomes
Extracellular vesicles isolated from cultured Damask rose cells, kept freeze-dried until you activate the kit. Plant-derived, they help condition and comfort the skin.
Niacinamide and tranexamic acid
Two well-studied actives in the balm phase that help soften the look of redness and uneven tone while supporting the barrier.
Madecassoside and panthenol
Madecassoside, from centella asiatica, joins panthenol and allantoin to soothe skin that feels tight or reactive.
Ceramide NP, cholesterol and squalane
Lipids naturally found in the skin barrier, with shea butter, to replenish dry, depleted skin and help limit moisture loss.
Curious about your ingredients?
Explore La Matière
A little guidance. A more considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore ASCEplus.
Find your place to begin.
Discover ASCEplus ExoBalm Plant-Derived Mixing Balm at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the ASCEplus collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.