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Serum A-Glyca

Sale price$230.00 CAD

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A.G.E. PROTECTION SERUM

Biologique Recherche Sérum A-Glyca is a targeted anti-glycation serum designed for skin beginning to show the first visible signs of aging.

Its formula focuses specifically on glycation — a biological process in which excess glucose can bind to structural proteins within the skin, including collagen and elastin. Over time, this process can affect the flexibility and mechanical properties of these proteins, contributing to wrinkles, reduced suppleness and visible changes in skin quality.

Sérum A-Glyca helps protect the skin against the glycation phenomenon while supporting a smoother, more supple and radiant-looking complexion.

It is particularly interesting for anyone wanting to take a more preventative approach to preserving the skin's structural quality as the first signs of aging begin to appear.

Skin Instant:

Recommended for Skin Instants showing the first visible signs of aging.

Particularly suited to skin experiencing:

  • Early fine lines and wrinkles
  • Reduced suppleness
  • Changes in skin firmness
  • A dull or tired-looking complexion
  • Skin that no longer feels as flexible as it once did
  • Early visible changes in overall skin quality
  • A desire to take a preventative approach to glycation-related skin aging
Benefits:
  • Helps protect against the glycation phenomenon
  • Helps prevent the visible effects associated with glycation
  • Supports the integrity of the skin's mechanical properties
  • Helps preserve skin suppleness
  • Helps improve the appearance of wrinkles
  • Restores visible vitality to tired-looking skin
  • Promotes a brighter, more radiant complexion
  • Supports a preventative approach to the first signs of skin aging
What Is Glycation — And Why Does It Matter for Skin?

Our bodies use glucose for energy.

When excess glucose binds to proteins within the skin, a natural chemical reaction called glycation can occur.

This process can create compounds known as Advanced Glycation End Products, or A.G.E.s.

Within the skin, glycation is particularly relevant because it can affect structural proteins such as collagen and elastin.

These proteins help give skin its:

  • Firmness
  • Flexibility
  • Suppleness
  • Structural support

When glycation affects these proteins, they can become more rigid and function less efficiently.

Over time, this may contribute to visible changes such as wrinkles, reduced suppleness and a complexion that appears less vibrant.

This is why Sérum A-Glyca is not simply another wrinkle serum.

Its focus is specifically on helping protect the skin against one biological mechanism associated with visible skin aging.

How to Use:

After cleansing, apply a few drops of Sérum A-Glyca morning and evening to the face, neck and décolleté.

Press gently into the skin using the palms of the hands until completely absorbed.

Within a Biologique Recherche routine, apply after cleansing and your appropriate Lotion P50 and before your moisturizer.

If using several serums, apply your more fluid serums first.

Avoid contact with the eyes. For external use only.

Loshen & Crem’s Recommendation:

Sérum A-Glyca is one of the more fascinating Biologique Recherche serums because it isn't simply asking, “Do you have wrinkles?”

It is looking at why skin structure changes over time.

We think about A-Glyca when a client tells us:

  • “I'm starting to see the first changes in my skin.”
  • “My skin doesn't feel as supple as it used to.”
  • “I want to be proactive instead of waiting for deeper wrinkles.”
  • “I'm noticing fine lines and changes in firmness.”
  • “I want to preserve the quality of my skin for as long as possible.”

This is where A-Glyca fits beautifully.

Rather than waiting until loss of density, firmness or wrinkles become more established, Sérum A-Glyca takes a targeted approach to one of the biological processes associated with those changes.

Think of it as structural preservation through an anti-glycation approach.

Sérum A-Glyca vs. Progeskin

Both address visible skin aging, but they focus on very different biological mechanisms.

Choose Sérum A-Glyca when the priority is:

  • Glycation
  • First signs of skin aging
  • Preserving suppleness
  • Protecting skin structural proteins
  • A preventative approach to wrinkles and loss of flexibility

Choose Progeskin when visible signs of skin aging are becoming more established and the concerns include:

  • Changes in firmness
  • Loss of tone
  • Reduced plumpness
  • Wrinkles
  • A broader change in overall skin quality

In the simplest terms:

  • A-Glyca = glycation protection + early signs of aging
  • Progeskin = broader visible aging + firmness + tone + plumpness

Depending on your Skin Instant, the two may sometimes complement one another within a professionally designed routine.

Sérum A-Glyca vs. Collagène Originel

Both are connected to collagen, but their purpose is very different.

Sérum A-Glyca focuses on helping protect structural proteins such as collagen and elastin from the effects associated with glycation.

Collagène Originel focuses more directly on visible wrinkles, loss of density, plumpness and the structural support of the skin.

Think:

  • A-Glyca → protect against glycation + preserve suppleness
  • Collagène Originel → density + structure + plumping + wrinkles

If you're beginning to notice the first visible changes in your skin, A-Glyca may be the more preventative choice.

If wrinkles are becoming more established and the skin appears thinner or less densely supported, Collagène Originel may be more targeted.

Ingredients:
  • Albizia Julibrissin Bark Extract: A botanical extract at the heart of Sérum A-Glyca's targeted anti-glycation formula.
  • Decarboxy Carnosine HCl: A carnosine-derived ingredient incorporated into the serum's A.G.E.-focused complex.
  • Glycerin: A humectant that helps maintain hydration and skin comfort.
  • Papaver Rhoeas Petal Extract: Red poppy extract included within the serum's skin-conditioning formula.
  • Butylene Glycol & Propylene Glycol: Humectant and conditioning ingredients that help support hydration and the serum's lightweight texture.

Full INCI List:

Water (Aqua), Albizia Julibrissin Bark Extract, Glycerin, Propylene Glycol, Phenoxyethanol, Decarboxy Carnosine HCl, Papaver Rhoeas Petal Extract, Butylene Glycol, Ethylhexylglycerin, Sodium Benzoate.

The lists of ingredients used in Biologique Recherche products are updated regularly. Before using a Biologique Recherche product, please refer to the ingredient list on its packaging.

If you have allergies or known ingredient sensitivities, please contact us at info@loshen.ca before purchasing. Our team will be happy to help verify the most current ingredient list for you.

Frequently Asked Questions

What is Biologique Recherche Sérum A-Glyca?

Sérum A-Glyca is an A.G.E. protection and anti-glycation facial serum from Biologique Recherche recommended for Skin Instants showing the first signs of skin aging.

It helps protect against the glycation phenomenon while supporting skin suppleness, radiance and vitality.

What is glycation in the skin?

Glycation is a natural chemical reaction in which excess glucose binds to proteins.

Within the skin, this can affect structural proteins such as collagen and elastin, making them more rigid and less able to perform their normal functions effectively.

What are Advanced Glycation End Products or A.G.E.s?

A.G.E.s are compounds produced through the glycation process.

They can bind to proteins within the skin and affect their normal mechanical properties, which is why glycation is associated with visible skin aging.

Does Sérum A-Glyca remove existing A.G.E.s?

Biologique Recherche currently describes Sérum A-Glyca as helping fight against and prevent the glycation phenomenon.

We would not describe it as literally removing all existing A.G.E.s or reversing glycation entirely. Its role is better understood as a targeted topical serum designed to help protect skin against this biological process.

Is A-Glyca only for people who eat a lot of sugar?

No.

Glycation is a biological process that can occur naturally within the body, so we would not choose Sérum A-Glyca based solely on someone's diet.

The more important question is whether its anti-glycation and preventative approach makes sense for your current Skin Instant.

Is Sérum A-Glyca an anti-wrinkle serum?

Yes. Biologique Recherche classifies A-Glyca as both anti-glycation and anti-wrinkle.

Its distinction is that it approaches visible skin aging through the specific mechanism of glycation rather than simply targeting wrinkles at the surface.

When should I start using Sérum A-Glyca?

Biologique Recherche recommends Sérum A-Glyca for Skin Instants showing the first signs of skin aging rather than prescribing it according to a specific age.

We prefer this approach because skin does not follow a birthday calendar.

What is the difference between A-Glyca and Progeskin?

A-Glyca focuses specifically on glycation and is recommended for the first signs of skin aging.

Progeskin takes a broader approach to visible aging and is designed to improve overall skin appearance, firmness, tone and plumpness.

What is the difference between A-Glyca and Collagène Originel?

A-Glyca focuses on protecting skin proteins from the glycation phenomenon.

Collagène Originel focuses more specifically on visible wrinkles, loss of density, plumping and the structural support of the skin.

Can I use A-Glyca with other Biologique Recherche serums?

Yes. Depending on your Skin Instant, A-Glyca may be layered with appropriate hydrating, firming or targeted Biologique Recherche serums.

More serum does not automatically mean better results, however. If you are unsure how to combine them, our skin experts can help simplify your routine.

Can I use Sérum A-Glyca every day?

Yes. Biologique Recherche currently recommends applying a few drops morning and evening.

When should I apply Sérum A-Glyca?

Apply it after cleansing and your appropriate Lotion P50. If using several serums, apply the most fluid serum first and follow with your moisturizer.

Who should use Sérum A-Glyca?

It is particularly suited to anyone noticing the first visible changes in skin firmness, suppleness, wrinkles or vitality and wanting to incorporate an anti-glycation approach into their routine.

Where can I buy Biologique Recherche Sérum A-Glyca?

Biologique Recherche Sérum A-Glyca is available from Loshen & Crem online and at our Edmonton, Alberta boutique.

Our skin experts can also help determine whether A-Glyca, Progeskin, Collagène Originel or another Biologique Recherche serum is best suited to your current Skin Instant.

Biologique Recherche Skin Reaction Policy

At Loshen & Crem, we highly recommend completing a consultation with one of our skin experts before introducing a new Biologique Recherche product into your routine.

In the event of a skin reaction, Biologique Recherche may require:

  • Clear photos of the reaction
  • Photos of the product and lot number
  • Proof of an online consultation with one of our skin experts

If you choose to purchase a Biologique Recherche product without a consultation and experience a reaction, we may be unable to provide a refund under the brand's policy.

If you are unsure whether Sérum A-Glyca is right for your Skin Instant, our team is always available to help.

Free Express Shipping with orders over $199

Available at our Edmonton Boutique

Ship to Canada only

Only 2 units left
Size:

Pickup available at Loshen & Crem

Usually ready in 24 hours

Serum A-Glyca | Serum - Glycation | LOSHEN & CREM

Serum A-Glyca

30 ml

Loshen & Crem

Pickup available, usually ready in 24 hours

5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada

+17807229086
Serum A-Glyca | Serum - Glycation | LOSHEN & CREM
Serum A-Glyca Sale price$230.00 CAD

A final gesture of care, a whisper of radiance.

La Touche Finale

In this short video, discover how to apply your Biologique Recherche Finishing Serum, a precious step in your ritual that elevates your skin to its most refined state.

With just a few drops, pressed gently into the skin, your complexion is left silky, luminous, and perfectly sealed.

  • 5 stars: 23 (88%)
  • 4 stars: 3 (12%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
O
Olga
Get It

Been incorporating it into my regime lately (45+)

L
Leah
Preventative

Been using this serum for two years now. Although it’s one of those that you cannot see visible result right away, just knowing that you’re doing something to your skin to prevent glycation is enough motivation to keep using it. Loshen’s customer service is outstanding too.

E
E.J.
Light weight and absorbs quickly

I use it for its anti glycation property. Very elegant texture.

H
Holly
Great product

I the anti glycation serum is very gentle to use and easy to incorporate into my skin regimen

L
L.
A staple in my regimen

I’ve been using this serum for a few years now and it does wonders for the lines on my forehead. Another amazing product from BR.

J
Jane
love it

This serum is also a real worker. I can visibly see the skin smooth out and add glow without any irritation. Also a great product for those starting anti-aging.

K
Khuraman
The best anti-aging serum!

This one beats le grand serum by far! It feels wonderful on the skin and when used consistently absolutely helps soften the lines! I also love how it goes well under any area and combines well with any serum. Cannot be without it in my routine!

K
Karina
Staple in my routine

Love this serum. It definitely helps smooth out my fine lines and makes me skin glow. You do have to use it consistently to see results. Definitely notice a difference when I don't use this serum!

J
Jessica
reduces redness

After using the product for a couple of weeks there's a noticeable reduction in redness on my skin.

J
Jenifer
SERUM A-GLYCA

Not seeing any real effects on my skin but otherwise fine. It has not caused any irritation / reaction.

A
AnnieD
A-glyca

I usually use this product in combination with elastine.

V
Vanessa
Staple product

This was the last serum I added to my already extensive BR routine. I didn’t think I needed this because i don’t consume a lot of sugar. But decided to try it since I’ve heard fantastic reviews. I’m glad I did! My skin tends to look inflamed and red when I eat things that cause inflammation. Since adding a glyca it has tremendously helped that inflamed look. I wake up with a more even complexion and my skin doesn’t look as angry regardless of what I ate. I’ve been using it 2x day as recommended and it agrees with my sensitive combo acne prone skin. Even though you think you don’t consume much sugar, it’s in everything so everyone needs this!

J
Jess
Love this

I've been using this daily for about a month and I love the results. I use this in combination with other serums. I read online that using it in upward motions helps, so that's what I do! My skin looks noticeably brighter and smoother, and less tired. Will definitely buy it again.

A
A.K.
The serum you didn’t know you needed!

I had never heard of Glycation, but now that I do, I’m so thankful for this serum! It is gentle and hydrating and my skin feels soothed when I use it.

L
Lucy
Great so far

Doesn't break me out which is always a concern. I'm in 30s without many wrinkles but trying to keep it that way!

C
C.
Amazing!!!!

Definitely a staple in my skincare regime! I’m on my second bottle now and am loving the results, skin is so dewy and soft! Serum is more of a liquid consistency but feels nice on the skin! Purchase it, you won’t regret it!!

J
Jessa
Need to be consistent

I didn’t realize that with this serum you are supposed to use everyday to see results (unlike other BR serums when you use as needed). So for that reason it gets 4 stars. I like mixing it up so it’s hard to say if i’ve seen results from this one

L
L.P.
Great for avoiding the ageing process

We all eat too much sugar now, and I didn’t realise the effects of eating too sugar on your skin. So I thought for me this would be a great purchase. I have only use one bottle of this, and I can say I’ve seen huge improvements yet. But it feels great, and it’s a serum I would defiantly buy again. It didn’t break me out, and I think with long term use the results would be amazing. So I’m excited to continue to use this.

K
Kate
Nice!

Not sticky and great for dull skin

W
Wendy
I will use the A Glyca til the end of time!

I went through 3 bottles and my skin is clear and glowy. I will never be without it.

K
Katie
Wow!

Super impressed with the result so far with this serum! Never thought I would need a anti glycation serum but definitely it makes a huge difference, I'm so happy I decided to give it a try. My skin looks way smoother and energized!

K
Kristen
Smooth & soft

Really love this serum. Wear it on my dehydrated skin all winter layered with TEWL and dermol rl

I
Ingrid

SERUM A-GLYCA

A
Asmae

A glyca

C
Cynthia
Glyca serum

love this serum.. amazing for aging skin!

M
Mady
Delivery

Everything about the package and product is great. Very satisfied