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Creme PTO Metamorphique

Sale price$232.00 CAD

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THE FACIAL ARCHITECTURE FIRMING CREAM

Formerly known as Crème ADN Métamorphique, Biologique Recherche Crème PTO Métamorphique is the next generation of the brand’s iconic firming cream — now specifically designed around one of the most visible changes in facial structure: ptosis.

Ptosis refers to the gradual downward shift that can occur when the skin loses structural support and facial contours become softer.

You may notice it first through the:

  • Cheeks
  • Jawline
  • Facial oval
  • Lower face
  • Neck

Crème PTO Métamorphique is designed for exactly this evolution.

Its firming, restructuring and tautening formula helps restore visible tone while making the contours of the face and neck appear more defined and harmonious.

With continued use, the complexion looks firmer and better supported, while the facial oval appears visibly refined.

This is not simply a moisturizer for “mature skin.”

It is a cream for facial architecture.

Skin Instant:

Recommended for Skin Instants lacking structure and tone.

We particularly think about Crème PTO Métamorphique when skin is experiencing:

  • Loss of firmness
  • Reduced facial tone
  • Softer-looking jawline
  • Changes in the facial oval
  • Visible sagging
  • Jowl formation
  • Reduced neck definition
  • Skin that appears less structurally supported
  • Changes associated with facial ptosis
What Is Facial Ptosis?

Ptosis is the term used to describe the visible downward movement of facial tissues as structural support weakens.

Several changes can contribute.

Over time:

  • Collagen decreases
  • Elastin changes
  • Facial muscles lose some tone
  • The skin becomes less resistant to gravity
  • Facial volumes can redistribute

As a result, areas that once appeared more defined may begin to look softer.

This can show up as:

  • Jowls
  • Reduced jawline definition
  • Softer cheeks
  • A less defined facial oval
  • Changes through the neck

This is why Crème PTO Métamorphique is more interesting than simply calling it a “lifting cream.”

It is designed around the visible architecture of the face.

Clinically Evaluated Facial Ptosis

In a Biologique Recherche clinical study, Crème PTO Métamorphique was applied twice daily for 56 days.

The study included 21 participants aged 46 to 65 with visible skin laxity.

After 56 days:

Facial ptosis was reduced by 6%

The result supports the cream’s targeted role in helping facial contours appear firmer and more defined with consistent use.

Why the Jawline Changes

The jawline is one of the places clients often notice structural changes first.

When the skin and underlying support network become less resistant to downward movement, the boundary between:

face → jaw → neck

can begin to appear less distinct.

That is why simply focusing on wrinkles does not necessarily address every visible sign of skin aging.

You can have relatively smooth skin and still notice:

“My jawline isn't what it used to be.”

That is not primarily a wrinkle conversation.

It is a structure + tone + contour conversation.

And that is precisely where PTO Métamorphique belongs.

How to Use:
  1. Apply Crème PTO Métamorphique morning and evening to the face, neck and décolleté.
  2. Massage using deep, upward movements until completely absorbed.
  3. Pay particular attention to areas where loss of tone or facial definition is most noticeable, including the lower cheeks, jawline and neck.

For external use only.

Loshen & Crem’s Recommendation:

Crème PTO Métamorphique is what we think about when a client tells us:

  • “My jawline is becoming softer.”
  • “I'm noticing jowls.”
  • “My skin doesn't feel as firm as it used to.”
  • “My neck is changing.”
  • “It's not really wrinkles that bother me — it's the shape.”
  • “I used to love Crème ADN Métamorphique. What replaces it?”

That last question is easy.

This does.

PTO Métamorphique is the evolution of Crème ADN Métamorphique, but we actually think its new positioning is much clearer.

ADN Métamorphique had a broad firming story.

PTO Métamorphique tells us exactly where to look:

facial contour + skin tone + ptosis.

If the jawline and facial oval are what you notice first in the mirror, this is one of the most targeted Biologique Recherche creams we would consider.

Formerly Crème ADN Métamorphique: What Changed?

Clients who loved Crème ADN Métamorphique will recognize the philosophy, but the formula itself has evolved significantly.

The previous generation contained ingredients such as:

  • DNA
  • Hydrolyzed Collagen
  • Hydrolyzed Elastin
  • Lanolin Oil
  • Niacinamide

The current PTO Métamorphique formula takes a completely different approach with:

  • Smithsonite Extract
  • Rye Seed Extract
  • Paeonia Albiflora Root Extract
  • Helichrysum Stoechas Extract
  • Alteromonas Ferment Extract
  • Plantago Lanceolata Extract
  • Baobab Pulp Extract
  • Goji Fruit Extract
  • Grape Juice Extract

This is not a minor packaging update.

It is a genuine reformulation and repositioning around visible loss of facial support and ptosis.

Crème PTO Métamorphique vs. VG Tensil

This is probably one of the most useful comparisons.

Both focus on firmness and tone.

But one is a serum and one is the finishing cream.

VG Tensil provides targeted serum support for:

  • Loss of tone
  • Skin laxity
  • Softer facial contours
  • Reduced definition

Crème PTO Métamorphique provides the moisturizing treatment step focused on:

  • Facial ptosis
  • Firmness
  • Jawline definition
  • Facial oval
  • Neck contour

Think:

  • VG Tensil → targeted firming serum
  • PTO Métamorphique → facial architecture cream

Depending on your Skin Instant, the two can make beautiful sense together.

Crème PTO Métamorphique vs. Sérum Matriciel Visage

These two products both belong in a structure-focused routine, but their roles differ.

Sérum Matriciel Visage is an intensive facial-structure serum focused on:

  • Facial volumes
  • Tissue support
  • Contours
  • Structural appearance

Crème PTO Métamorphique provides:

  • Daily moisturizing support
  • Firmness
  • Tautening
  • Facial oval definition
  • Neck contour support

Think:

  • Matriciel Visage → targeted structural serum
  • PTO Métamorphique → daily structural cream

For clients whose primary concern is visible change in facial architecture, this is one of the most logical combinations to discuss.

Crème PTO Métamorphique vs. Platysma

This is a matter of daily treatment vs. intensive mask.

Platysma is a single-use 20-minute treatment targeted specifically to:

  • The chin
  • Jawline
  • Submental area
  • Lower facial contour

Crème PTO Métamorphique is the daily treatment for:

  • Facial ptosis
  • Loss of firmness
  • Facial oval
  • Neck contour
  • Ongoing structural support

Think:

  • Platysma → immediate lower-face treatment
  • PTO Métamorphique → everyday facial-contour cream
Is PTO Métamorphique a “Lifting Cream”?

You will often see it described that way, and visually that is certainly the goal.

But we prefer more precise language.

Crème PTO Métamorphique is officially positioned as:

  • Firming
  • Restructuring
  • Tautening

Its clinical study specifically evaluated facial ptosis.

So rather than promising that a cream physically lifts facial tissues in the same way as a procedure, we describe the result as:

firmer-looking skin + more defined facial contours + reduced visible ptosis.

That is both accurate and meaningful.

Ingredients:
  • Smithsonite Extract: A mineral-derived ingredient appearing very high in the current formula and incorporated into the cream’s protective and skin-supporting complex.
  • Secale Cereale (Rye) Seed Extract: Rye-derived botanical extract incorporated into the firming formulation.
  • Paeonia Albiflora Root Extract: White Peony Root Extract included within the targeted skin-supporting complex.
  • Helichrysum Stoechas Extract: Botanical extract incorporated into the formula’s firming and conditioning system.
  • Alteromonas Ferment Extract: Marine-derived ferment included within the restructuring formula.
  • Adansonia Digitata Pulp Extract: Baobab-derived ingredient incorporated into the current formulation.
  • Plantago Lanceolata Extract: Plantain-derived botanical ingredient included within the contour-focused formula.
  • Lycium Barbarum Fruit Extract: Goji berry extract providing botanical skin-conditioning support.
  • Vitis Vinifera Grape Juice Extract: Grape-derived ingredient incorporated into the antioxidant-supporting complex.
  • Glycerin: Helps support hydration and skin comfort.
  • Hydrogenated Lecithin: Helps condition the skin and support the lipid environment of the formula.
  • Tocopherol: Vitamin E provides antioxidant and conditioning support.
Full INCI List:

Water (Aqua), Coco-Caprylate/Caprate, Caprylic/Capric Triglyceride, C10-18 Triglycerides, Smithsonite Extract, Glycerin, C12-16 Alcohols, Methylpropanediol, Cetyl Alcohol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid, Pentaerythrityl Tetrastearate, Caprylyl Glycol, Tapioca Starch, Isomalt, Secale Cereale (Rye) Seed Extract, Maltodextrin, 1,2-Hexanediol, Propanediol, Phenylpropanol, Paeonia Albiflora Root Extract, Polysorbate 60, Sorbitan Isostearate, Tocopherol, Helichrysum Stoechas Extract, Helianthus Annuus (Sunflower) Seed Oil, Alteromonas Ferment Extract, Phenethyl Alcohol, Adansonia Digitata Pulp Extract, Lecithin, Lycium Barbarum Fruit Extract, Vitis Vinifera (Grape) Juice Extract, Benzyl Alcohol, Cinnamal, Cinnamyl Alcohol, Plantago Lanceolata Extract, Potassium Sorbate, Sodium Benzoate, Xanthan Gum.

The lists of ingredients used in Biologique Recherche products are updated regularly. Before using a Biologique Recherche product, please refer to the ingredient list on its packaging.

If you have allergies or known ingredient sensitivities, please contact us at info@loshen.ca before purchasing. Our team will be happy to help verify the most current ingredient list for you.

Questions We Get About Crème PTO Métamorphique

What is Biologique Recherche Crème PTO Métamorphique?

Crème PTO Métamorphique is a firming, restructuring and tautening facial cream designed specifically for Skin Instants lacking structure and tone.

It focuses on visible facial ptosis and helps the face and neck appear firmer and more defined.

Is Crème PTO Métamorphique the replacement for Crème ADN Métamorphique?

Yes.

Crème PTO Métamorphique is the current generation of the former Crème ADN Métamorphique.

The product has been extensively reformulated and is now positioned more specifically around facial ptosis and contour definition.

What does PTO mean?

PTO refers to the cream’s focus on ptosis, the visible downward shift that occurs as facial structural support and elasticity decrease.

What is facial ptosis?

Facial ptosis describes visible sagging or downward movement of facial tissues associated with reduced structural support.

It can contribute to jowls, softer facial contours and reduced jawline definition.

Does Crème PTO Métamorphique help jowls?

Biologique Recherche specifically connects facial ptosis with the development of jowls.

The cream is designed to improve visible firmness and contour definition and has been clinically evaluated for reduction in facial ptosis.

Does PTO Métamorphique help the jawline?

Yes.

Facial oval and neck definition are central to its current positioning, making it particularly relevant when the jawline appears softer or less defined.

Can I use Crème PTO Métamorphique on my neck?

Yes.

Biologique Recherche specifically instructs application to the face, neck and décolleté.

Does Crème PTO Métamorphique lift the neck?

It is designed to help the neck and facial contours appear firmer and more defined.

We would describe this as a cosmetic firming and tautening effect rather than permanent structural lifting.

What were the clinical results?

In a Biologique Recherche clinical study involving 21 participants aged 46 to 65 with visible skin laxity, Crème PTO Métamorphique was applied twice daily for 56 days.

Facial ptosis was reduced by 6%.

How long does PTO Métamorphique take to work?

The current clinical study assessed results after 56 days of twice-daily use.

Skin feel and hydration may be noticed sooner, but meaningful contour-focused results should be evaluated with consistent use over time.

Is Crème PTO Métamorphique only for mature skin?

Biologique Recherche does not currently recommend it according to a specific age.

It is recommended according to the Skin Instant — specifically skin lacking structure and tone.

That is the approach we prefer.

Skin does not check your birth certificate before losing firmness.

Does Crème PTO Métamorphique stimulate collagen and elastin?

Biologique Recherche explains that decreases in collagen and elastin contribute to facial ptosis.

However, the current consumer page does not make a broad direct claim that the finished cream clinically stimulates collagen, elastin and hyaluronic acid synthesis.

We therefore prefer to describe it according to its proven result:

improved visible firmness + more defined contours + reduced facial ptosis.

Is PTO Métamorphique good for wrinkles?

It may improve the overall appearance of firmer, more supported skin, but its primary current indication is loss of structure, tone and facial contour.

If wrinkles are your main concern, a more specifically wrinkle-focused cream or serum may be more appropriate.

What is the difference between PTO Métamorphique and VG Tensil?

VG Tensil is a targeted serum focused on loss of firmness and tone.

PTO Métamorphique is the daily moisturizing cream specifically positioned around facial ptosis, facial oval and neck contour.

What is the difference between PTO Métamorphique and Platysma?

Platysma is a single-use 20-minute firming mask targeted specifically to the jawline and submental area.

PTO Métamorphique is an everyday cream used morning and evening to support facial and neck contours over time.

Can I use PTO Métamorphique with Sérum Matriciel Visage?

Depending on your Skin Instant, yes.

Both belong to the broader structural and contour-focused Biologique Recherche category, with Matriciel Visage providing the serum step and PTO Métamorphique providing the cream step.

Can I use Crème PTO Métamorphique every day?

Yes.

Biologique Recherche currently recommends applying it morning and evening.

How much should I use?

Apply enough to comfortably cover the face, neck and décolleté and massage with deep upward movements until absorbed.

The current Biologique Recherche instructions do not specify that every client must use a particular “hazelnut-sized” amount.

Where can I buy authentic Biologique Recherche Crème PTO Métamorphique?

Biologique Recherche Crème PTO Métamorphique is available from Loshen & Crem online and at our Edmonton, Alberta boutique.

Our skin experts can also help determine whether PTO Métamorphique, VG Tensil, Sérum Matriciel Visage, Platysma or another Biologique Recherche firming treatment best suits your current Skin Instant.

Biologique Recherche Skin Reaction Policy

At Loshen & Crem, we highly recommend completing a consultation with one of our skin experts before introducing a new Biologique Recherche product into your routine.

In the event of a skin reaction, Biologique Recherche may require:

  • Clear photos of the reaction
  • Photos of the product and lot number
  • Proof of an online consultation with one of our skin experts

If you choose to purchase a Biologique Recherche product without a consultation and experience a reaction, we may be unable to provide a refund under the brand's policy.

If you are unsure whether Crème PTO Métamorphique is right for your Skin Instant, our team is always available to help.

Free Express Shipping with orders over $199

Available at our Edmonton Boutique

Ship to Canada only

In stock
Size:

Pickup available at Loshen & Crem

Usually ready in 24 hours

Biologique Recherche Crème PTO Métamorphique firming cream for facial ptosis jawline and neck

Creme PTO Metamorphique

50 ml

Loshen & Crem

Pickup available, usually ready in 24 hours

5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada

+17807229086
Biologique Recherche Crème PTO Métamorphique firming cream for facial ptosis jawline and neck
Creme PTO Metamorphique Sale price$232.00 CAD

A final gesture of care, a whisper of radiance.

La Touche Finale

In this short video, discover how to apply your Biologique Recherche Finishing Serum, a precious step in your ritual that elevates your skin to its most refined state.

With just a few drops, pressed gently into the skin, your complexion is left silky, luminous, and perfectly sealed.

  • 5 stars: 28 (97%)
  • 4 stars: 1 (3%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
R
Rochelle
Love it!

Deeply hydrating and instantly comforting on the skin. I started using this when my skin was feeling quite dehydrated, and I noticed a visible difference almost immediately — my skin felt restored, healthier, and much more balanced. I also love the texture; it feels luxurious and nourishing without being heavy.

K
K
Nice texture

Nice texture, hydrating, have not noticed a difference in skin laxity or “lifting” but I have not been using long enough to judge and I don’t believe a cream is a fix for a facelift- I would recommend this for it’s hydrating effects and the hope of tighter skin - it’s a buy for sure for me !!!

M
Micheline
HYDRATING

Crème douce et super hydratante J'ADORE !!!!!

O
Olga
Get It

I've been a fan of ADN version ... enjoying it so far ...

C
Catherine
New favourite

I got the old version after trying a sample - I was pleasantly surprised! It leaves the skin hydrated and nourished without a greasy finish. I can’t speak to the lifting benefits yet but my skin feels firmer.

A
Amanda
Hydrating!

I’ve loved this creme, my skin feels soft and hydrated without feeling greasy

V
Victoria
Very hydrating

I'm from Alberta and have dry sensitive acne prone skin. I struggle to find a moisturizer that doesn't break me out, doesn't irritate my skin and is hydrating enough! This one fits the bill! Finally a moisturizer that I don't have to use half the jar to not feel like a raisin!!

R
RL
A Game Changer for Radiant, Youthful Skin!

I’ve been using CREME ADN METAMORPHIQUE for a few weeks now, and I am absolutely impressed with the results! This cream has transformed the texture of my skin, leaving it smoother, firmer, and deeply hydrated. I love how lightweight it feels, yet it delivers intense moisture without being greasy. My complexion looks more radiant, and I’ve noticed a visible reduction in fine lines. It’s become a staple in my skincare routine, and I highly recommend it for anyone looking for a luxurious and effective anti-aging cream!”

L
Letisha
Very very lovely

This moisturizer is very light and yet very nourishing and soothing on the skin. It has a lovely smell and sits well under makeup. I haven’t been using it long enough to see results but love using it as a day cream. Gives a nice glow 🥰

C
Christina
Hydration!

Love love love this moisturizer! Easily absorbs and hydrates my dry skin

H
H.
Acne-Approved

ADN has the most luxurious, soft texture unlike any cream I’ve used. It melts into the skin and leaves your skin calm, glowing and nourished for the day. Love that it’s for aging skin but also repairs the barrier! And in case you needed yet another reason to use this cream, it’s incredible on adult-acne. My VISIA showed much less inflammation and breakouts when I used this paired with Osmosis stemfactor. Would purchase over and over again!

v
vanessa
Great texture

For such a hydrating cream this does not get greasy or pill-which a lot do. Love all BR but this one is especially soothing

H
Halyna

Love the texture of the cream, my skin felt plumped right after the first time I use it

B
Bella
Creme ADN Metamorphique

This is my 2nd or 3rd bottle of Creme ADN Metamorphique and I love it. It's good for summer or winter months. Leaves my skin feeling hydrated and soft - even in the morning! Highly recommend this cream!

T
Tetiana
excellent crème

excellent crème

K
Kevin
Excellent

This cream really does work wonders and I have now purchased another jar - - -Love BR products.

N
Nancy
Plumping but gentle

I have to admit that I was skeptical about this cream when I received it as a sample but enjoyed it so much that I'm about to buy the full size, really plumps and firms the face and doesn't irritate my sensitive skin prone to breakouts.

K
Kevin
It works wonders

This cream does what it says it does and it's made a Hugh difference to the lines and crows feet around my eyes. Easy to apply, goes on evenly and has a nice texture. Very impressed with the BR product line.

W
Wendy
BR did it again!

I would be repurchasing this cream again when I run out. It firms and hydrates my skin nicely.

K
Khuraman
Incredibly firming!!

I am only 34 and do not have fine lines (thank you serum elastine and the new collagene one!) but I do have my skin sagging especially around my mouth and this cream does an incredible job both firming and sort of lifting as well as acting like a moisturizer. I am a combo/normal skin and this one sinks right in and I love that it is a pearly cream and not one of their brown creams as this one adds some light and the brown creams make my face look dull. Thank you BR and Loshen for shipping it SO FAST!

L
LR
Lifting, plumping + hydrating!

I'm very impressed with the softening of lines in my forehead + the improvement in the volume of the skin under my eyes! I'm also noticing that the results from my micro current use (NuFace device) are more noticeable + last longer when I'm using this creme regularly; it's very supportive in maintaining the lifting + toning effects. Very happy to have this product in my rotation.

m
m.D.
Love it

I really like this cream, the best combination with the Elastine serum!

A
A.K.
Does it all!

I can’t believe there’s a cream that tightens and plumps my skin, while the active ingredients protect my skin from signs of aging. I received a sample size and would absolutely repurchase!

L
L
Beautiful

An exceptional firming and hydrating cream. Would definitely repurchase.

O
Olga
Perfect moisturizer

BR has such an amazing assortment, it's so hard to choose the perfect match. I'm 40+ with sensitive/reactive/combination-to-dry skin and this moisturizer is an intense anti-aging treatment providing fantastic hydration!

I
Ingrid
Great product

Fantastic service. Great product

E
Elaine
“Beautiful”

This cream absorbs beautifully into the skin leaving it feeling soft but firm as described it would. I will definitely repurchase!!!!

K
Kate
Better than the old version

Not smelly

M
MARIAM
Great all purpose creme

Love this lightweight fast absorbing effective creme. Tones and lifts and plumps. Perfect for neck and décolleté.