Your routine
BiophoraCalming Toner
Why it fits
A calming toner with witch hazel, aloe and chamomile to prepare reactive skin.
Biophora Ultimate Refining Serum
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Explore La Crem rewardsBiophora’s brightening, refining serum with niacinamide, vitamin C and peptides, for uneven tone and redness-prone skin. In the evening.
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Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Biophora
Ultimate Refining Serum
Your ritual begins with the right choice.
$126.00 CAD
Taxes calculated at checkout.
The skincare focus
Biophora Ultimate Refining Serum
Biophora’s brightening, refining serum with niacinamide, vitamin C and peptides, for uneven tone and redness-prone skin. In the evening.
Explore our ingredient glossaryBiophora
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
Niacinamide
Vitamin B3 helps brighten, even out the look of tone and calm the look of redness, while supporting the skin’s barrier.
Vitamin C
Ethyl ascorbic acid is a stable form of vitamin C that helps brighten a dull complexion and defend the skin against environmental stress.
Peptides
A blend of oligopeptides and polypeptides supports smoother, more refined-looking skin.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Your routine
BiophoraNight Protection
Why it fits
Biophora’s lightweight barrier cream that seals in hydration overnight, for dry, dehydrated or sensitized skin. The last step of your evening routine.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
Biophora Ultimate Refining Serum
Biophora’s brightening, refining serum with niacinamide, vitamin C and peptides, for uneven tone and redness-prone skin. In the evening.
The serum we suggest when skin is uneven and reactive at the same time, the client who wants brightness but turns red with most brightening products. Niacinamide, a stable vitamin C and peptides work on tone, while hops and centella calm the look of redness. Skin looks brighter, more even and more refined, and feels hydrated.
Benefits
- Brightens a dull complexion
- Helps even out the look of tone and dark spots
- Calms the look of redness
- Refines the look of skin texture
- Keeps skin hydrated and comfortable
How to use
- Start with clean skin: Cleanse and pat your skin dry.
- Tone: Sweep on your toner and let it dry.
- Apply the serum: Over a clean, dry face, every evening.
- Seal it in: Follow with your moisturizer or Night Protection.
Precautions
Full Ingredient List
Water, Hamamelis Virginiana (Witch Hazel) Extract, Niacinamide, Glycosaminoglycans, Propylene Glycol, Gluconolactone, Humulus Lupulus (Hops) Cone Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Salvia Officinalis (Sage) Leaf Extract, Equisetum Arvense Extract, Citrus Limon (Lemon) Extract, Centella Asiatica Extract, Pinus Sylvestris Bud Extract, Ethyl Ascorbic Acid, Glycerin, Hydroxypropyl Cyclodextrin – Palmitoyl Tripeptide-38, Maltodextrin, Swertia Chirata Extract, Sodium PCA, Sodium Lactate, Arginine, Aspartic Acid, PCA, Glycine, Alanine, Serine, Valine, Proline, Threonine, Isoleucine, Histidine, Phenylalanine, Allantoin, Sodium Benzoate, Lecithin, Acetyl Glutamine, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Bacillus/Folic Acid Ferment Extract, Sodium Hyaluronate, Xanthan Gum, Potassium Sorbate, Sodium Benzoate, Kappaphycus Alvarezii Extract, Caesalpinia Spinosa Fruit Extract, Carboxymethyl Betaglucan.
Shipping & returns
For delivery and return information, view our policy.
Biophora’s brightening, refining serum with niacinamide, vitamin C and peptides, for uneven tone and redness-prone skin. In the evening.
The serum we suggest when skin is uneven and reactive at the same time, the client who wants brightness but turns red with most brightening products. Niacinamide, a stable vitamin C and peptides work on tone, while hops and centella calm the look of redness. Skin looks brighter, more even and more refined, and feels hydrated.
Key ingredients
- Niacinamide: brightens and calms the look of redness
- Ethyl ascorbic acid (vitamin C): a stable antioxidant that brightens
- Peptides: for a smoother, more refined look
- Hops and centella asiatica: soothing botanicals that calm the look of redness
How to use
- Cleanse and pat your skin dry.
- Apply nightly to a clean, dry face.
- Follow with your moisturizer or Night Protection.
- Use as recommended by your esthetician.
Wear a broad-spectrum SPF during the day to protect your results. If you have a diagnosed skin condition, book a consultation with us before adding it to your routine.
Full ingredient list
Water, Hamamelis Virginiana (Witch Hazel) Extract, Niacinamide, Glycosaminoglycans, Propylene Glycol, Gluconolactone, Humulus Lupulus (Hops) Cone Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Salvia Officinalis (Sage) Leaf Extract, Equisetum Arvense Extract, Citrus Limon (Lemon) Extract, Centella Asiatica Extract, Pinus Sylvestris Bud Extract, Ethyl Ascorbic Acid, Glycerin, Hydroxypropyl Cyclodextrin – Palmitoyl Tripeptide-38, Maltodextrin, Swertia Chirata Extract, Sodium PCA, Sodium Lactate, Arginine, Aspartic Acid, PCA, Glycine, Alanine, Serine, Valine, Proline, Threonine, Isoleucine, Histidine, Phenylalanine, Allantoin, Sodium Benzoate, Lecithin, Acetyl Glutamine, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Bacillus/Folic Acid Ferment Extract, Sodium Hyaluronate, Xanthan Gum, Potassium Sorbate, Sodium Benzoate, Kappaphycus Alvarezii Extract, Caesalpinia Spinosa Fruit Extract, Carboxymethyl Betaglucan.
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your order01 · Across Canada
A good thing, on its way.
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
Niacinamide
Vitamin B3 helps brighten, even out the look of tone and calm the look of redness, while supporting the skin’s barrier.
Vitamin C
Ethyl ascorbic acid is a stable form of vitamin C that helps brighten a dull complexion and defend the skin against environmental stress.
Peptides
A blend of oligopeptides and polypeptides supports smoother, more refined-looking skin.
Hops and centella
Hops cone and centella asiatica extracts help calm the look of redness and keep reactive skin comfortable.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore Biophora.
Find your place to begin.
Discover Biophora Ultimate Refining Serum at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Biophora collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.