Your routine
GlyMed PlusComfort Cream with Aloe Vera
Why it fits
A light yet deeply nourishing moisturizer designed to hydrate, soothe, and protect compromised, reactive, or sensitized skin.
GlyMed Revitalizing Essence with NAD+
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Explore La Crem rewardsExperience unmatched hydration and rejuvenation with the Revitalizing Essence with NAD+, a revolutionary essence formulated to deeply replenish moisture and restore vitality at the cellular level. Infused with NAD+, Acetyl Tetrapeptide-2, Echinacea, and Hyaluronic Acid, this transformative formula enhances your skin’s natural barrier, soothes inflammation, and prepares skin to effectively absorb subsequent treatments.
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Boutique details
Your Edmonton boutique.
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Shipping, on usRegular $149+ · Priority $249+ CAD
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GlyMed Plus
GlyMed Revitalizing Essence with NAD+
Your ritual begins with the right choice.
$70.00 CAD
Taxes calculated at checkout.
The skincare focus
GlyMed Revitalizing Essence with NAD+
Experience unmatched hydration and rejuvenation with the Revitalizing Essence with NAD+, a revolutionary essence formulated to deeply replenish moisture and restore vitality at the cellular level. Infused with NAD+, Acetyl Tetrapeptide-2, Echinacea, and Hyaluronic Acid, this transformative formula enhances your skin’s natural barrier, soothes inflammation, and prepares skin to effectively absorb subsequent treatments.
Explore our ingredient glossaryGlyMed Plus
The formula, explained.
The ingredients behind this formula—and what they bring to your skin.
NAD+ (Nicotinamide Adenine Dinucleotide)
Supports cellular energy and renewal, visibly restoring skin vitality.
Acetyl Tetrapeptide-2
Helps reinforce skin elasticity, firmness, and resilience.
Echinacea Extract
Provides calming properties, reducing redness and inflammation.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Pairs beautifully.
Explore another step in your face-care routine.
Your routine
GlyMed PlusGlyMed Mega Cream Cleanser
Why it fits
GlyMed Plus Mega Cream Cleanser is an ultra-gentle cream cleanser that effectively dissolves makeup and oil, providing a deep, yet soothing and hydrating cleanse. It is designed to be both thorough and gentle, ensuring that the skin is left clean, soft, and moisturized.
Worth knowing
The finer details.
A closer look at your skin, your routine and what goes into the formula.
GlyMed Revitalizing Essence with NAD+
Experience unmatched hydration and rejuvenation with the Revitalizing Essence with NAD+, a revolutionary essence formulated to deeply replenish moisture and restore vitality at the cellular level. Infused with NAD+, Acetyl Tetrapeptide-2, Echinacea, and Hyaluronic Acid, this transformative formula enhances your skin’s natural barrier, soothes inflammation, and prepares skin to effectively absorb subsequent treatments.
Benefits
- Deeply hydrates and replenishes moisture levels
- Boosts cellular rejuvenation and vitality
- Strengthens and restores skin’s protective barrier
- Reduces inflammation and calms reactive skin
- Evens skin tone and texture for a refreshed appearance
How to use
- After cleansing, dispense 5–10 drops onto palms.
- Gently press the essence onto face, neck, and décolleté.
- Follow with your favourite GlyMed Plus serums and moisturizer.
- Use morning and night for optimal results.
Full Ingredient List
Aqua (Water/Eau), Polysorbate 20, Pentylene Glycol, Mattodextrin, Glycerin, Propanediol, Phenoxyethanol, Fructooligosaccharides, Beta Vulgaris Root Extract, Citrullus Lanatus Fruit Extract, Lens Esculenta Fruit Extract, Pyrus Malus Fruit Extract, Oryza Sativa Extract, Potassium Lactate, Ethylhexylglycerin, Citrus Sinensis Osbeck Peel Oil Cold Pressed, Sodium Lactate, Sodium PCA, Potassium Sorbate, Sodium Benzoate, Lactic Acid, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Hydrolyzed Sodium Hyaluronate, Helianthius Annus Sprout Extract, Acetyl Tetrapeptide-2, Caprylyl Glycol, Camellia Sinensis Leaf Extract, Echinacea Purpurea Extract, Leuconostoc/Radish Root Ferment Filtrate, Paullinia Cupana Seed Extract, Chamomilla Recutita Flower Extract, Leuconostoc Ferment Filtrate, Superoxide Dismutase, Soybean Peroxidase, Tocopherol, Citric Acid, Limonene
Shipping & returns
For delivery and return information, view our policy.
Experience unmatched hydration and rejuvenation with the Revitalizing Essence with NAD+, a revolutionary essence formulated to deeply replenish moisture and restore vitality at the cellular level. Infused with NAD+, Acetyl Tetrapeptide-2, Echinacea, and Hyaluronic Acid, this transformative formula enhances your skin’s natural barrier, soothes inflammation, and prepares skin to effectively absorb subsequent treatments.
Recommended for:
- All skin types, including sensitive or reactive skin
- Dry, dehydrated, or compromised skin
- Pre- and post-treatment care
- Skin showing signs of aging, dullness, or inflammation
Benefits:
- Deeply hydrates and replenishes moisture levels
- Boosts cellular rejuvenation and vitality
- Strengthens and restores skin’s protective barrier
- Reduces inflammation and calms reactive skin
- Evens skin tone and texture for a refreshed appearance
How to use:
- After cleansing, dispense 5–10 drops onto palms.
- Gently press the essence onto face, neck, and décolleté.
- Follow with your favourite GlyMed Plus serums and moisturizer.
- Use morning and night for optimal results.
Loshen & Crem’s recommendation:
Enhance your skincare ritual by pairing the Revitalizing Essence with GlyMed Plus Age Delay Cream or Cell Protection Serum to seal in hydration and maximize rejuvenation benefits. Excellent as part of your daily routine or to soothe skin following professional treatments.
Ingredients:
- NAD+ (Nicotinamide Adenine Dinucleotide): Supports cellular energy and renewal, visibly restoring skin vitality.
- Acetyl Tetrapeptide-2: Helps reinforce skin elasticity, firmness, and resilience.
- Echinacea Extract: Provides calming properties, reducing redness and inflammation.
- Hyaluronic Acid Complex: Deeply hydrates and plumps skin for visibly smoother, younger-looking results.
Full INCI List:
Aqua (Water/Eau), Polysorbate 20, Pentylene Glycol, Mattodextrin, Glycerin, Propanediol, Phenoxyethanol, Fructooligosaccharides, Beta Vulgaris Root Extract, Citrullus Lanatus Fruit Extract, Lens Esculenta Fruit Extract, Pyrus Malus Fruit Extract, Oryza Sativa Extract, Potassium Lactate, Ethylhexylglycerin, Citrus Sinensis Osbeck Peel Oil Cold Pressed, Sodium Lactate, Sodium PCA, Potassium Sorbate, Sodium Benzoate, Lactic Acid, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Hydrolyzed Sodium Hyaluronate, Helianthius Annus Sprout Extract, Acetyl Tetrapeptide-2, Caprylyl Glycol, Camellia Sinensis Leaf Extract, Echinacea Purpurea Extract, Leuconostoc/Radish Root Ferment Filtrate, Paullinia Cupana Seed Extract, Chamomilla Recutita Flower Extract, Leuconostoc Ferment Filtrate, Superoxide Dismutase, Soybean Peroxidase, Tocopherol, Citric Acid, Limonene
The care behind your order
From our boutique.
To your door.
A few helpful details, before your next delivery.
Track your order01 · Across Canada
A good thing, on its way.
$149+Free Regular shipping
$249+Free Priority shipping
CAD · After discounts, before taxes and shipping. Conditions and product exclusions apply.
Canada & U.S. delivery details02 · Close to home
Collect in Edmonton.
Choose pickup at checkout when available. We’ll let you know when your order is ready.
Speak with our boutique03 · Care you can count on
Here after checkout, too.
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
NAD+ (Nicotinamide Adenine Dinucleotide)
Supports cellular energy and renewal, visibly restoring skin vitality.
Acetyl Tetrapeptide-2
Helps reinforce skin elasticity, firmness, and resilience.
Echinacea Extract
Provides calming properties, reducing redness and inflammation.
Hyaluronic Acid Complex
Deeply hydrates and plumps skin for visibly smoother, younger-looking results.
Curious about your ingredients?
Explore La Matière
Expert guidance. A considered routine.
Your skin.
Our attention.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book a consultation Just a product question? Ask us.Personal guidance, in Edmonton or online.
The care behind your care
A place in your routine.
A team in your corner.
From your first question to your next replenishment, there’s a real person here to help.
01 Make sense of what you already use
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our team02 Get to know your skin
Take our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting point03 Keep the conversation going
A question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Explore GlyMed Plus.
Find your place to begin.
Discover GlyMed Revitalizing Essence with NAD+ at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the GlyMed Plus collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
Care, to keep.
Your ritual, beautifully noted.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. Your reminder, with your team still in reach.