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Le Mieux24 Hr. Age Defying Cream
Why it fits
A Loshen & Crem bestseller for lasting moisture, barrier support and smoother, firmer-looking skin

Skincare Boutique & Facial Institute
Skincare Boutique & Facial Institute
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Explore La Crem rewardsA mineral and amino acid facial mist for immediate hydration and calmer, more comfortable-looking skin
Discover the formula & ingredientsPickup in Edmonton
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5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
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Le Mieux
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$18.00 CAD
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The skincare focus
A mineral and amino acid facial mist for immediate hydration and calmer, more comfortable-looking skin
Explore our ingredient glossaryLe Mieux
The ingredients behind this formula—and what they bring to your skin.
Glycine
An amino acid that helps condition and support hydrated-looking skin.
Serine
Supports moisture balance and skin softness.
Proline
An amino acid that contributes to the formula’s skin-conditioning benefits.
Ingredient imagery is illustrative. Explore the full ingredient list below.
Made to work together
Explore another step in your face-care routine.
Your routine
A Loshen & Crem bestseller for lasting moisture, barrier support and smoother, firmer-looking skin
Your routine
A nourishing peptide cleanser for soft, supple and comfortably clean skin
Worth knowing
A closer look at your skin, your routine and what goes into the formula.
A mineral and amino acid facial mist for immediate hydration and calmer, more comfortable-looking skin
Le Mieux Iso-Cell Recovery Solution is a lightweight toner mist formulated with biomimetic amino acids, mineral salts and moisture-binding ingredients to refresh skin experiencing dryness, tightness or temporary visible redness.
The water-light formula combines glycine, serine, proline, arginine and other amino acids with zinc, potassium, magnesium, calcium and copper compounds. Sodium PCA, sorbitol and glucose complement the mineral complex by helping the skin attract and maintain moisture.
Use it after cleansing, following a workout, during travel or whenever the complexion feels warm, dry or stressed. Iso-Cell Recovery Solution can help skin feel more comfortable, but it is not a treatment for rosacea, inflammatory skin conditions or sunburn.
Aqua, Glycine, Calcium Chloride, Serine, Oligopeptide-223, Copper Gluconate, Potassium Chloride, Alanine, Magnesium Aspartate, Glucose, Proline, Arginine, Magnesium Chloride, Zinc Gluconate, Lysine, Citric Acid, Sodium Citrate, Sodium Acetate, Threonine, Glutamic Acid, Sodium PCA, Sorbitol, Propanediol, Sodium Chloride, Zinc Acetate, Pentylene Glycol, Caprylyl Glycol, Ethylhexylglycerin.
Ingredient lists may change. Always refer to the product packaging for the most current ingredient list, particularly if you have allergies or sensitivities. Contact info@loshen.ca if you need help reviewing the formula before purchasing.
For delivery and return information, view our policy.
A mineral and amino acid facial mist for immediate hydration and calmer, more comfortable-looking skin
Le Mieux Iso-Cell Recovery Solution is a lightweight toner mist formulated with biomimetic amino acids, mineral salts and moisture-binding ingredients to refresh skin experiencing dryness, tightness or temporary visible redness.
The water-light formula combines glycine, serine, proline, arginine and other amino acids with zinc, potassium, magnesium, calcium and copper compounds. Sodium PCA, sorbitol and glucose complement the mineral complex by helping the skin attract and maintain moisture.
Use it after cleansing, following a workout, during travel or whenever the complexion feels warm, dry or stressed. Iso-Cell Recovery Solution can help skin feel more comfortable, but it is not a treatment for rosacea, inflammatory skin conditions or sunburn.
Iso-Cell Recovery Solution is particularly well suited to:
Although Le Mieux recommends the formula for sensitive skin, individual tolerance varies. Avoid applying it to severely burned, blistered, infected or openly wounded skin unless directed by a qualified healthcare professional.
Iso-Cell Recovery Solution is more than a water mist. Its formula combines humectants with amino acids and electrolytes commonly associated with the skin’s natural hydration environment.
The current formula also includes zinc, copper and magnesium compounds alongside Oligopeptide-223. Unlike Iso-Rose Hydrating Mist, it does not contain rose water, rose oil or other aromatic botanical ingredients, making Iso-Cell the more straightforward option for fragrance-reactive skin.
Le Mieux’s updated 5.1 oz packaging features a refined nozzle that produces a finer, more controlled mist. A 2 oz format is also available for travel or on-the-go use.
Use after cleansing, morning and evening, or throughout the day as needed.
Close the eyes and mist generously over the face, neck and décolleté. Gently press the solution into the skin with clean hands and follow with serum and moisturizer while the skin remains slightly damp.
To use as a traditional toner, spray the solution onto a cotton pad and gently sweep it over clean skin. Do not scrub.
After exercise or travel, mist over the complexion to refresh skin affected by perspiration, dry air or environmental exposure. It may also be applied over makeup by holding the bottle farther from the face and allowing the fine mist to settle naturally.
Iso-Cell Recovery Solution is one of those uncomplicated products that can make an active skincare routine feel considerably more comfortable. It is especially useful when the skin feels tight after cleansing or when exfoliating acids and retinoids have left the complexion needing more hydration.
Apply it immediately after cleansing and follow with Hyaluronic Serum while the skin is still slightly damp. Seal everything in with moisturizer—because a mist can add hydration, but it cannot replace the protective role of a cream.
Keep the 2 oz bottle in your handbag, travel kit or gym bag for easy refreshment. The larger 5.1 oz bottle is ideal for the bathroom counter and daily routines.
If the skin is persistently red, burning, swollen, blistered or painful, a facial mist is not the answer. Pause potentially irritating products and consult a dermatologist or healthcare professional when appropriate.
Iso-Cell Recovery Solution can also be misted between skincare layers, but additional applications do not replace serum, moisturizer or sunscreen.
Both Le Mieux mists provide amino acids, minerals and lightweight hydration, but their sensorial profiles and supporting ingredients differ.
Neither mist replaces a hydrating serum or moisturizer. Their role is to add a light layer of hydration, support skin comfort and prepare the complexion for the products that follow.
Full Ingredient List:
Aqua, Glycine, Calcium Chloride, Serine, Oligopeptide-223, Copper Gluconate, Potassium Chloride, Alanine, Magnesium Aspartate, Glucose, Proline, Arginine, Magnesium Chloride, Zinc Gluconate, Lysine, Citric Acid, Sodium Citrate, Sodium Acetate, Threonine, Glutamic Acid, Sodium PCA, Sorbitol, Propanediol, Sodium Chloride, Zinc Acetate, Pentylene Glycol, Caprylyl Glycol, Ethylhexylglycerin.
Ingredient lists may change. Always refer to the product packaging for the most current ingredient list, particularly if you have allergies or sensitivities. Contact info@loshen.ca if you need help reviewing the formula before purchasing.
It is both. Use it as a post-cleansing toner before serum or mist it over the skin throughout the day for lightweight hydration and refreshment.
Le Mieux recommends Iso-Cell Recovery Solution for all skin types, including sensitive skin. Its published formula contains no added fragrance, essential oils or drying alcohol. Very reactive skin should still patch test before widespread use.
No. It may help skin affected by dryness or temporary visible redness feel more comfortable, but it does not treat rosacea or another inflammatory skin condition. Those concerns should be managed with guidance from a dermatologist or qualified healthcare professional.
The fine mist may feel refreshing on warm, dry skin after sun exposure, but it is not a treatment for sunburn. Do not rely on it for blistered, severely painful or extensively burned skin, and seek medical advice when appropriate.
Yes. Mist it over the complexion after exercising to refresh skin affected by perspiration and heat. If the skin is visibly soiled or heavily perspiring, cleanse or rinse first rather than using the mist as a substitute.
Yes. The 2 oz size is particularly convenient for travel. It can help refresh skin affected by dry indoor environments or airplane cabins, although moisturizer remains necessary for preventing moisture loss.
No. Iso-Cell Recovery Solution adds water, humectants, amino acids and minerals, but it does not provide the emollient or occlusive layer of a moisturizer. Follow with serum and cream to help retain hydration.
Yes. It does not contain an exfoliating acid or retinoid and can be incorporated into an active routine to support hydration. However, it cannot prevent or reverse irritation caused by excessive exfoliation or overuse of retinoids.
Yes. Hold the bottle away from the face, close the eyes and allow the fine mist to settle without rubbing. Applying too much at once may disturb makeup.
The current published ingredient list contains no parfum, essential oils or aromatic flower waters. This makes it the more appropriate Le Mieux mist for clients avoiding fragrance.
Yes. The formula is lightweight and non-oily and contains zinc compounds that support a balanced-looking complexion. It is not an acne medication and should not be presented as a treatment for breakouts.
It may be appropriate after certain treatments, but post-procedure instructions vary considerably. Use only products approved by the professional who performed your peel, laser, microneedling or other procedure.
Use it morning and evening after cleansing or reapply throughout the day whenever the skin needs lightweight hydration. If repeated misting leaves the skin feeling tight, follow with moisturizer rather than continuing to add water alone.
The published formula does not list retinoids or exfoliating acids. However, individual health circumstances vary, so consult your physician or qualified healthcare provider if you have concerns about introducing a new product during pregnancy or breastfeeding.
It can support hydration and skin comfort after exposure to dry air, heat, travel or perspiration, but it is not a sunscreen or a substitute for protective skincare. Apply broad-spectrum sunscreen every morning.
The care behind your order
A few helpful details, before your next delivery.
Track your order01 · Across Canada
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Speak with our boutique03 · A little reassurance
Request an eligible return within 30 days. Items must be unopened, unused and in their original packaging. Final-sale exclusions apply.
Returns & order support
An amino acid that helps condition and support hydrated-looking skin.
Supports moisture balance and skin softness.
An amino acid that contributes to the formula’s skin-conditioning benefits.
Helps condition the skin and support a comfortable-looking complexion.
Additional amino acids that complement the biomimetic hydration complex.
A skin-conditioning peptide included in the current formula.
An electrolyte that supports the formula’s mineral balance.
Mineral compounds that help condition the skin.
Support a calmer, more balanced-looking complexion.
Provides mineral-based skin-conditioning support.
A component associated with the skin’s natural moisturizing factors that attracts moisture.
Humectants that help maintain softness and hydration.
Curious about your ingredients?
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A little guidance. A more considered routine.
Beautiful formulas are only part of the story. Knowing what belongs in your routine makes all the difference.
Talk through your skin, the products you already use and the questions on your mind with one of our facialists.
Book your consultation Just a product question? Ask us.The care behind your care
From your first question to your next replenishment, there’s a real person here to help.
You don’t need to start over. Bring us your current routine and we’ll help you understand where a new formula fits.
Ask our teamTake our skin questionnaire for a thoughtful starting point, then speak with us if you’d like to explore your recommendations.
Find your starting pointA question about how to use it? Unsure about your next step? You’re welcome to come back to our team for guidance.
We’re here to helpFrom our Edmonton boutique
Discover Le Mieux Iso-Cell Recovery Solution at Loshen & Crem, a skin-health boutique and facial studio in Edmonton, Alberta. Explore the Le Mieux collection online across Canada, or speak with our facialists about how this formula fits into the products you already use.
A little care, to keep.
The guidance you’ll want when you get home: how to use it, what to expect and when to check in. A little reminder, with your team still in reach.