Exfoliating Night Cream for Blemishes, Congested Pores and Excess Oil

Dermaceutic Activabiome, formerly known as Actibiome, is an exfoliating night cream formulated for oily, combination and blemish-prone skin.

Its concentrated formula combines 7% glycolic acid and 1% salicylic acid with a 2% purifying active and a 2% microbiota regulator. Together, these ingredients help exfoliate accumulated skin cells, unclog congested-looking pores, reduce excess oil and improve the appearance of blemishes and redness.

Used in the evening, Activabiome supports the skin’s natural overnight renewal process while helping maintain a balanced skin microbiota. With consistent use, skin appears clearer, smoother and more refined.

The vegan and non-comedogenic formula is suitable for all skin types but is especially beneficial for oily, combination and acne-prone skin.

Benefits

• Helps visibly reduce blemishes and imperfections
  
• Improves the appearance of blemish-related redness
  
• Exfoliates accumulated dead skin cells
  
• Helps unclog congested-looking pores
  
• Visibly minimizes enlarged-looking pores
  
• Helps regulate the appearance of excess oil
  
• Smooths rough and uneven-looking skin texture
  
• Supports a balanced skin microbiota
  
• Promotes clearer and healthier-looking skin
  
• Works overnight to support skin renewal
  
• Non-comedogenic
  

Best For

Dermaceutic Activabiome is especially suitable for skin experiencing:

• Emerging or recurring blemishes
  
• Acne-prone skin
  
• Excess oil and visible shine
  
• Congested or clogged-looking pores
  
• Blackheads and uneven congestion
  
• Blemish-related redness
  
• Rough or uneven skin texture
  
• Combination and oily skin
  
• Skin accustomed to glycolic and salicylic acids

How It Works

Activabiome combines surface exfoliation, pore-refining action and microbiota-supporting ingredients within one overnight cream.

• Glycolic acid is an alpha hydroxy acid that helps loosen the bonds between accumulated dead skin cells. This supports more efficient exfoliation and helps improve the appearance of rough texture, dullness and visible imperfections.
• Salicylic acid is an oil-soluble beta hydroxy acid that helps work within congested-looking pores. It supports the removal of excess oil and accumulated skin cells that can contribute to blackheads and blemishes.
• The microbiota regulator provides nutrients that help support the skin’s natural microbial balance, while the marine algae-inspired purifying complex helps reduce excess oil and soothe the appearance of redness.

Together, these ingredients help refine pores, smooth uneven texture and support a clearer-looking complexion overnight.

Clinical Results

In an in vivo study evaluating Activabiome in combination with Oxybiome over 28 days:

• 100% agreed that their skin felt healthy and fresh
  
• 100% agreed that the routine visibly tightened pores and reduced imperfections and redness
  
• 100% agreed that their skin appeared clearer, smoother and free from impurities
  
• Papules were reduced by 65%

The study was conducted on 23 volunteers by an independent European research organization. These results reflect the combined Oxybiome and Activabiome routine rather than Activabiome used alone. Individual results may vary.

How to Use

1. Apply in the evening to clean, completely dry skin.
2. Distribute a small amount over the face and neck, avoiding the eye contour, eyelids, lips and mucous membranes.
3. When introducing Activabiome, begin two or three evenings per week. Gradually increase the frequency according to skin tolerance.
4. Sensitive skin may begin with application every other evening.

• Allow the cream to absorb before applying an additional moisturizer when more hydration or comfort is needed.
• Do not apply to irritated, sensitized or broken skin.
• Avoid using Activabiome in the same routine as retinol, other AHAs, BHAs, exfoliating scrubs or intensive resurfacing treatments.
• Apply a broad-spectrum SPF 50 every morning and limit unprotected sun exposure.
• Dermaceutic does not recommend Activabiome during pregnancy or breastfeeding because of its concentration of exfoliating fruit acids.

Loshen & Crem’s Recommendation

Dermaceutic Activabiome is an excellent evening treatment for clients experiencing recurring blemishes, excess oil, visible pores and uneven skin texture.

Because the formula already combines glycolic and salicylic acids, keep the rest of the evening routine simple. Avoid layering exfoliating cleansers, acid toners, scrubs or retinol on the same evening.

For a complete blemish-prone skin routine, cleanse first with Dermaceutic Oxybiome and follow with a thin layer of Activabiome. This is the combination used in Dermaceutic’s published 28-day study.

Clients experiencing dehydration alongside blemishes may layer a simple, non-comedogenic moisturizer over Activabiome or alternate it with a barrier-supporting evening routine.

Temporary mild tingling may occur when the product is first introduced. Persistent burning, redness or excessive flaking is a sign to reduce the frequency and focus on restoring the skin barrier.

Daily sunscreen is essential when using glycolic and salicylic acids.

Ingredients

• 7% Glycolic Acid: An alpha hydroxy acid that exfoliates accumulated dead skin cells and supports the skin’s natural renewal process. It helps improve the appearance of blemishes, rough texture and enlarged-looking pores.
• 1% Salicylic Acid: An oil-soluble beta hydroxy acid that helps unclog congested-looking pores, reduce excess sebum and improve the appearance of blemishes and blackheads.
• 2% Purifying Active: A biomimetic active inspired by the natural defence system of marine algae. It helps reduce excess oil and supports clearer, calmer-looking skin.
• 2% Microbiota Regulator: A blend of nutrients that helps support the skin’s natural microbiota and improve the appearance of redness and imperfections.
• Chlorella Vulgaris and Laminaria Digitata Extracts: Marine algae extracts that provide soothing, conditioning and microbiota-supporting benefits.
• Betaine: Helps maintain hydration and comfort while supporting the skin’s moisture balance.
• Glycerin: A humectant that attracts moisture to the skin and helps reduce dryness during exfoliation.

Full Ingredient List

Water (Aqua), Caprylic/Capric Triglyceride, Glycolic Acid, Propylene Glycol, Dimethicone, Glycerin, Betaine, Cetearyl Alcohol, Glyceryl Stearate, PEG-100 Stearate, Ammonia, Salicylic Acid, Zinc Sulfate, Chlorella Vulgaris Extract, Laminaria Digitata Extract, Maris Aqua (Sea Water), Saccharide Isomerate, Tetrasodium Glutamate Diacetate, Hydrolyzed Algin, Sclerotium Gum, Citronellyl Methylcrotonate, Fragrance (Parfum), Phenethyl Alcohol, Chlorphenesin, Sodium Hydroxide, O-Cymen-5-Ol.

Ingredient lists may be updated by the manufacturer. Refer to the product packaging for the most current ingredient information.

Frequently Asked Questions

What is Dermaceutic Activabiome used for?

Activabiome is an exfoliating night cream designed to improve the appearance of blemishes, clogged-looking pores, excess oil, redness and uneven skin texture.

Is Activabiome the same product as Actibiome?

Yes. Activabiome was previously called Actibiome. The current product name is Dermaceutic Activabiome.

Does Activabiome contain glycolic acid?

Yes. The current Activabiome formula contains 7% glycolic acid.

Does Activabiome contain salicylic acid?

Yes. It contains 1% salicylic acid to help address excess oil, congestion and blemish-prone skin.

Is Activabiome suitable for acne-prone skin?

Yes. It is specifically formulated for acne-prone and blemish-prone skin. The formula is also non-comedogenic.

Can Activabiome help with blackheads?

Its salicylic acid and glycolic acid help exfoliate accumulated skin cells and refine congested-looking pores, which may improve the appearance of blackheads.

Can Activabiome help with post-acne marks?

Activabiome may help improve uneven texture and the appearance of marks left behind after blemishes. More persistent brown pigmentation may benefit from a targeted pigmentation serum or cream.

How often should I use Activabiome?

Begin two or three evenings per week and gradually increase the frequency according to skin tolerance. Dermaceutic recommends applying it every other evening when the skin is sensitive.

Can Activabiome be used every night?

Yes. It is designed for regular evening use, but nightly application should only begin after the skin develops a comfortable tolerance.

Is tingling normal when using Activabiome?

Temporary mild tingling may occur because the formula contains glycolic and salicylic acids. Reduce the frequency if persistent burning, redness, discomfort or excessive flaking develops.

Can I use Activabiome with retinol?

Avoid applying Activabiome and retinol in the same evening routine. Alternating them on different nights may be appropriate for experienced users under professional guidance.

Can I use Activabiome with Foamer 15 or Mask 15?

Avoid using multiple concentrated exfoliating products in the same routine. Alternate Activabiome with Foamer 15 or Mask 15 to reduce the risk of over-exfoliation.

What cleanser should I use with Activabiome?

Dermaceutic recommends pairing Activabiome with Oxybiome Micellar Water as part of its blemish-prone skin protocol.

Is Activabiome suitable for dry skin?

Dermaceutic identifies Activabiome as suitable for all skin types, but its exfoliating formula is especially beneficial for oily, combination and blemish-prone skin. Dry skin should introduce it gradually and use additional barrier support when needed.

Can I use Activabiome around my eyes?

No. Avoid the eye contour, eyelids and the area immediately beneath the eyes.

Do I need sunscreen while using Activabiome?

Yes. Apply a broad-spectrum SPF 50 every morning. Glycolic and salicylic acids exfoliate the skin and may increase sensitivity to sun exposure.

Can Activabiome be used during pregnancy or breastfeeding?

No. Dermaceutic does not recommend Activabiome during pregnancy or breastfeeding because of its high concentration of glycolic acid.

Is Activabiome fragrance-free?

No. The current ingredient list contains fragrance.

Is Activabiome silicone-free?

No. The current formula contains dimethicone.

Is Activabiome vegan?

Yes. Dermaceutic identifies Activabiome as vegan.