

Progeskin Serum
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CUTANEOUS RE-NEW SERUM
Sérum Progeskin
Sérum Progeskin is a targeted firming serum created for skin beginning to show visible changes in firmness, elasticity and resilience.
Its formula focuses on two proteins associated with the skin aging process, Progerin and Klotho, helping support the skin’s natural renewal mechanisms and preserve its vitality over time.
With consistent use, the skin appears firmer, smoother and more toned, while fine lines and wrinkles look softened. It is an excellent choice when the skin feels less dense, less bouncy or simply not as resilient as it once was.
Skin Instant:
Best suited to skin showing visible signs of aging, including fine lines, wrinkles, loss of firmness, reduced elasticity or sagging.
We especially recommend Sérum Progeskin when the priority is maintaining skin quality, firmness and resilience as the skin changes over time.
Benefits:
- Regulates Progerin synthesis to promote epidermal rejuvenation
- Preserves cell longevity by stimulating Klotho protein synthesis
- Restructures the dermis for anti-aging and anti-wrinkle effects
- Improves firmness and elasticity for a more lifted, toned appearance
- Stimulates the skin’s internal regeneration process, ensuring long-term skin health
How to Use:
Apply a few drops of Progeskin Serum onto clean skin, covering the face, neck, and décolleté in gentle upward movements until fully absorbed.
Avoid contact with the eyes.
Use morning and/or evening, as part of your anti-aging routine.
Loshen & Crem’s Recommendation:
Think of Sérum Progeskin when your concern goes beyond dehydration or dullness and you are beginning to notice a real change in the skin’s firmness, bounce or definition.
This is a beautiful serum for skin that feels softer, thinner or less resilient than it once did, or for anyone wanting to be proactive about maintaining skin quality over time.
How to integrate it into a firming routine:
- If skin shows early signs of aging and needs protection → Use with Sérum A-Glyca to prevent glycation and maintain skin’s youthfulness.
- If skin lacks firmness and contour definition → Pair with Crème MSR-H Visage to enhance elasticity and sculpt facial features.
- If skin appears dull and needs revitalization → Follow with Masque Biomagic to boost radiance and refine texture.
Ingredients:
- Centaurea Cyanus Flower Extract: Known for its soothing properties, it helps improve the skin’s overall tone and texture.
- Juglans Regia (Walnut) Seed Extract: Rich in antioxidants, it protects the skin from environmental stress and supports rejuvenation.
- Juglans Regia (Walnut) Shell Extract: Helps to promote skin regeneration and preserve youthful-looking skin.
- Trifluoroacetyl Tripeptide-2: Stimulates collagen production, promoting a firmer, more toned appearance.
- Xanthan Gum: A natural gum used for its hydrating and skin-smoothing properties.
- Dextran & Disodium EDTA: Improve skin hydration and protect skin integrity from environmental damage.
Full Ingredients List:
WATER (AQUA), PROPANEDIOL, PENTYLENE GLYCOL, GLYCERIN, EMPETRUM NIGRUM FRUIT JUICE, TAPIOCA STARCH, CAESALPINIA SPINOSA FRUIT EXTRACT, SECALE CEREALE (RYE) SEED EXTRACT, HYDROLYZED LUPINE PROTEIN, KAPPAPHYCUS ALVAREZII EXTRACT, HELICHRYSUM STOECHAS EXTRACT, ALTEROMONAS FERMENT EXTRACT, SCLEROTIUM GUM, MALTODEXTRIN, PULLULAN, XANTHAN GUM, SILICA, LYSOLECITHIN, 1,2-HEXANEDIOL, CAPRYLYL GLYCOL, PHENETHYL ALCOHOL, POTASSIUM SORBATE, SODIUM HYDROXIDE.
Ingredients are subject to change at the manufacturer’s discretion. For the most complete and up-to-date list, refer to the product packaging.
📄 Biologique Recherche Skin Reaction Policy 📄
At Loshen & Crem, we highly recommend a consultation with one of our skin experts before introducing a new Biologique Recherche product into your routine. Skin is individual, and choosing the right formula for your Skin Instant is an important part of getting the best experience from the brand.
In the event of a skin reaction, Biologique Recherche requires:
- Clear photos of the reaction
- Photos of the product and lot number, located on the packaging
- Proof of an online consultation with one of our skin experts
If you choose to purchase a Biologique Recherche product without a consultation and experience a reaction, we may be unable to provide a refund under the brand’s policy.
If you are unsure whether Sérum Progeskin is right for your skin, our team is always here to help you build a routine that makes sense for you.
Complimentary shipping from $149 and priority shipping from $249
Available at our Edmonton Boutique
Ship to Canada only
Pickup available at Loshen & Crem
Usually ready in 24 hours

Progeskin Serum
30 ml
Loshen & Crem
5238 Windermere Boulevard
Edmonton AB T6W 0L9
Canada
Returns & Refunds
At Loshen & Crem, we understand that sometimes, even the most carefully chosen product might not be "the one."
- Returns: You have 30 days from delivery to return any unopened and unused products in perfect condition—just as they arrived.
- Refunds: If your return reaches us within 30 days from delivery, you’ll have the choice between a refund or store credit (your preference, naturellement). After 30 days, store credit is your only option. Beyond 40 days, refunds and credits are no longer possible.
Final Sale Items
Promotional Items: Products purchased at a discount during promotions are considered final sale and cannot be returned or exchanged.
Final Markdown Items: Items marked as Final Markdown are non-returnable, non-exchangeable, and non-refundable.
Hair Care Products, Nail Polishes, Nail Treatments & Makeup: Due to hygiene and quality control standards, all purchases in these categories are final and cannot be returned, exchanged, or refunded.
Electrical Devices : Electrical devices are final sale for change-of-mind returns — we're unable to offer returns, exchanges, or refunds if you simply change your mind. If a device arrives defective or develops a fault, please see our Warranties section below for manufacturer warranty support.
Seasonal Items: Seasonal and limited-edition items are final sale and cannot be returned, exchanged, or refunded.
Gift Cards: Gift cards are final sale and non-refundable.
Please note: Final sale means no exchanges, refunds, or credits are available.
In-Store Purchases: For products purchased at our Edmonton boutique, our return policy remains consistent. You are invited to return items directly to the store, allowing you to bypass shipping concerns. Kindly note that our opening hours may vary. For the latest information, please click Loshen & Crem Opening hours.
Final Sale on Store Credit Purchases: Any items purchased using store credit issued from a previous return will be considered final sale. These items are not eligible for further returns or exchanges.
Shipping Policy
CAD: Loshen & Crem offers regular and priority shipping on eligible Canadian orders.
- Orders under $149: 27.95 priority shipping.
- Orders of $149 or more: complimentary regular shipping.
- Orders of $249 or more: complimentary priority shipping.
Shipping thresholds are calculated after discounts and before taxes. Any applicable shipping charges will be displayed at checkout.
Alberta & British Columbia: 1–2 business days
Manitoba & Saskatchewan: 1–2 business days
Quebec & Ontario: 1–2 business days
Newfoundland & Labrador, Nova Scotia, P.E.I. & New Brunswick: 1–3 business days
USA:
Complimentary shipping is available on orders of $350 USD or more. Orders below this threshold are subject to a $35 USD shipping fee. Promotional shipping rates may apply during MistleGlow.
West Coast: 2–3 business days
Midwest: 2–3 business days
East Coast: 3–4 business days
Please note that additional processing time may apply, and deliveries to remote areas may take longer.
Note: Shipping rates are subject to change without notice. Delivery times are estimates and cannot be guaranteed, as carrier delays may occur.
We aim to dispatch your order within 2 business days, though peak sales and payment verifications may require a touch more patience.
Please note that if you make any changes with the courier after the dispatch, our carrier will charge a $32 fee. In addition, we will have to withdraw 800 points from your La Crème Points account. We appreciate your understanding.
Our processing time starts from the moment your order is successfully submitted and may take up to 2 business days to dispatch your order. However, please be aware that processing and handling time may be extended during peak sale periods. Before we can ship your order, we may need to hold your order for payment verification and confirm your details with your card issuer.
We will do our very best to minimize delays.
Shipping Rates & Delivery Times
Estimated Delivery Times (Canada):
- British Columbia & Alberta: 1–2 business days
- Manitoba & Saskatchewan: 1–2 business days
- Quebec & Ontario: 1–2 business days
- Atlantic Provinces: 1–3 business days
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United States: Delivery times vary by region:
- Zone 1: Eastern States – 3–4 business days
- Zone 2: Central States – 4–5 business days
- Zone 3: Western States – 5 business days
Remote areas may experience longer shipping times.Please Note: Shipping windows are estimates and not guarantees. Delays may occur due to weather, traffic, or additional verification processes.
Shipping Address Details
For a smooth delivery, please provide all relevant information, including buzzer codes, directional suffixes (North, South, etc.), or special instructions.
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Address Changes: Once your package has left our warehouse, address updates cannot be made. If you need to make changes before dispatch, email us at info@loshen.ca with your order details.
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Carrier Fees: Any changes made with the courier after dispatch will incur a $32 CAD fee, and the Free Express Shipping option will be deducted from your La Crème Points account.
Tracking Your Order
All shipments include tracking information, so you can follow your package from our warehouse to your door. A confirmation email with your tracking number will be sent once your order is dispatched.
Damaged or Lost Packages
- Damaged Parcels: If your order arrives damaged, please contact us at info@loshen.ca with photos and details. We’ll work to resolve the issue promptly.
- Lost or Stolen Packages: If your package is marked "delivered" but hasn’t arrived, please contact the carrier directly to file a claim.
Tips to Avoid Lost or Stolen Packages:
- Opt for a signature upon receipt (required for orders over $350 CAD).
- Have your package delivered to your workplace.
- If you’re not home on the expected delivery date, ask a neighbor to receive your package.
Unclaimed Parcels
If your package is returned to us unclaimed, we’ll issue a refund minus a $29.95 CAD return shipping fee.
Free Samples
We believe every order deserves a little extra care! Expect 1–3 complimentary samples selected by our Skincare Specialists to perfectly complement your order.
Loyalty Rewards: La Crem Points
Earn La Crème Points with every purchase and redeem them for future orders. From time to time, we also offer Free Gifts With Purchase (GWP) for select brands, but these are available only while supplies last.
At Loshen & Crem, we aim to deliver excellence at every step of your skincare journey, with care and a touch of elegance. Questions? Don’t hesitate to reach out—we’re always happy to assist!
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A final gesture of care, a whisper of radiance.
La Touche Finale
In this short video, discover how to apply your Biologique Recherche Finishing Serum, a precious step in your ritual that elevates your skin to its most refined state.
With just a few drops, pressed gently into the skin, your complexion is left silky, luminous, and perfectly sealed.






